A Wireless Power-Free Pressure Sensor for Real-Time In Vivo Gastrointestinal Pressure Monitoring

2014 ◽  
Vol 609-610 ◽  
pp. 993-996
Author(s):  
Qiang Shi ◽  
De Yong Chen ◽  
Jun Bo Wang ◽  
Kai Kai Bao ◽  
Li Juan Liu

A wireless and power-free pressure sensor system capable of real time in vivo gastrointestinal pressure monitoring has been developed. This system contains a sensor unit and a detection unit. Based on mutual inductance detection mechanism, the sensor is featured with simple device structure and therefore low cost. The packaged sensor unit was tested. Results obtained from experiment demonstrated that this sensor has a sensitivity of 0.2115 kHz / kPa within a pressure range-10~30 kPa. The in vivo testing result not only indicates a period of 2 contractions per minute peristalsis of rabbit stomach but also validates the feasibility of this real time wireless gastrointestinal pressure monitoring system.

Sensors ◽  
2020 ◽  
Vol 20 (16) ◽  
pp. 4591 ◽  
Author(s):  
Pablo Blázquez-Carmona ◽  
Manuel Sanchez-Raya ◽  
Juan Mora-Macías ◽  
Juan Antonio Gómez-Galán ◽  
Jaime Domínguez ◽  
...  

For the monitoring of bone regeneration processes, the instrumentation of the fixation is an increasingly common technique to indirectly measure the evolution of bone formation instead of ex vivo measurements or traditional in vivo techniques, such as X-ray or visual review. A versatile instrumented external fixator capable of adapting to multiple bone regeneration processes was designed, as well as a wireless acquisition system for the data collection. The design and implementation of the overall architecture of such a system is described in this work, including the hardware, firmware, and mechanical components. The measurements are conditioned and subsequently sent to a PC via wireless communication to be in vivo displayed and analyzed using a developed real-time monitoring application. Moreover, a model for the in vivo estimation of the bone callus stiffness from collected data was defined. This model was validated in vitro using elastic springs, reporting promising results with respect to previous equipment, with average errors and uncertainties below 6.7% and 14.04%. The devices were also validated in vivo performing a bone lengthening treatment on a sheep metatarsus. The resulting system allowed the in vivo mechanical characterization of the bone callus during experimentation, providing a low-cost, simple, and highly reliable solution.


2009 ◽  
Vol 17 (25) ◽  
pp. 22735 ◽  
Author(s):  
V. Raimondi ◽  
G. Agati ◽  
G. Cecchi ◽  
I. Gomoiu ◽  
D. Lognoli ◽  
...  
Keyword(s):  
Low Cost ◽  

2012 ◽  
Vol 30 (1) ◽  
pp. 80 ◽  
Author(s):  
Su Jin Kim ◽  
Dong Sup Lee ◽  
Jong Chan Kim ◽  
Ho Young Lee ◽  
Bumkyoo Choi ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Qiufang Wang ◽  
Yumei Shen

This paper combines flexible pressure sensing technology, wireless sensor network, and cloud platform technology to design and manufacture a medical miniature pressure sensor and its supporting system. The problem of noninvasive monitoring of the syndrome encountered in the clinic is used for real-time monitoring and auxiliary diagnosis of the disease. Different from the current clinical use of “puncture” to measure intrafascial pressure, this system focuses on the noninvasive monitoring of compartment syndrome, using medical tape to paste a flexible microsensing unit on the injured area. The flexible sensor unit can measure the pressure here in real time and then can know the pressure in the fascia chamber. The flexible pressure sensor unit combines with the subsequent flexible circuit to send the measured data to the data in real time through wireless communication. The data aggregation node transmits the collected data to the upper computer through serial communication, and the upper computer software processes and stores the data and uploads it to the cloud server. In this experiment, it was observed that the concentrations of Ca and P showed the same fluctuating trend. With the gradual progress of the stretch, the concentrations of Ca and P increased with the increase in time, reaching approximately at the end of the extension. The peak value indicates that the osteoclast activity is enhanced at this time, the bone matrix is largely destroyed, and the Ca and P in the matrix are released into the serum in a large amount, thereby increasing the serum concentration. After the distraction ceases, it enters the healing period of the callus. At this time, the concentrations of Ca and P decrease with the increase in time and gradually reach a stable level, indicating that the osteoblast activity is enhanced at this time, the bone matrix begins to rebuild, and the Ca and P gradually increase. The deposited bone matrix gradually forms new bone and finally reaches a balance. Since the speed of extension in each experimental group is inconsistent, the time required to reach the same extension length is also inconsistent, so that the peak time is also inconsistent. After plotting the stress difference ( △ F ) before and after stretching against time and speed, it is found that the relationship is linear. However, these two variables affect △ F at the same time, so they cannot be isolated. Based on this, this subject uses multiple regression equations to fit the three relationships of stress difference ( △ F ), time, and speed. In the process of distraction osteogenesis, with each distraction, the bone stress presents a trend from high to low. And as the stretch progresses, the measured stress value increases linearly at the same time point every day.


2017 ◽  
Vol 17 (22) ◽  
pp. 7394-7404 ◽  
Author(s):  
Kun Ho Kim ◽  
Jeong Oen Lee ◽  
Juan Du ◽  
David Sretavan ◽  
Hyuck Choo

NANO ◽  
2019 ◽  
Vol 14 (07) ◽  
pp. 1950081 ◽  
Author(s):  
Wendan Jia ◽  
Qiang Zhang ◽  
Yongqiang Cheng ◽  
Dong Zhao ◽  
Yan Liu ◽  
...  

Flexible pressure sensors based on piezoresistive induction have recently become a research hotspot due to the simple device structure, low energy consumption, easy readout mechanism and excellent performance. For practical applications, flexible pressure sensors with both high sensitivity and low-cost mass production are highly desirable. Herein, this paper presents a high-sensitivity piezoresistive pressure sensor based on a micro-structured elastic electrode, which is low cost and can be mass-produced by a simple method of sandpaper molding. The micro-structure of the electrode surface under external pressure causes a change in the effective contact area and the distance between the electrodes, which exhibits great pressure sensitivity. The test results show that the surface structure is twice as sensitive as the planar structure under low pressure conditions. This is because of the special morphology of silver nanowires (AgNWs), which exhibits the tip of nanostructures on the surface and realizes the quantum tunneling mechanism. The sensor has high sensitivity for transmitting signals in real time and it can also be used to detect various contact actions. The low cost mass production and high sensitivity of flexible pressure sensors pave the way for electronic skin, wearable healthcare monitors and contact inspection applications.


Biosensors ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 157
Author(s):  
Daniela Vieira ◽  
Francis McEachern ◽  
Romina Filippelli ◽  
Evan Dimentberg ◽  
Edward J Harvey ◽  
...  

A variety of brain disorders such as neural injury, brain dysfunction, vascular malformation, and neurodegenerative diseases are associated with abnormal levels of oxygen. Current methods to directly monitor tissue oxygenation in the brain are expensive and invasive, suffering from a lack of accuracy. Electrochemical detection has been used as an invasiveness and cost-effectiveness method, minimizing pain, discomfort, and injury to the patient. In this work, we developed a minimally invasive needle-sensor with a high surface area to monitor O2 levels in the brain using acupuncture needles. The approach was to directly etch the iron from stainless steel acupuncture needles via a controlled pitting corrosion process, obtaining a high microporous surface area. In order to increase the conductivity and selectivity, we designed and applied for the first time a low-cost coating process using non-toxic chemicals to deposit high surface area carbon nanoparticle, catalytically active laccase, and biocompatible polypyrrole. The physicochemical properties of the materials were characterized as well as their efficacy and viability as probes for the electrochemical detection of PO2. Our modified needles exhibited efficient electrocatalysis and high selectivity toward O2, with excellent repeatability. We well engineered a small diagnostic tool to monitor PO2, minimally invasive, able to monitor real-time O2 in vivo complex environments.


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