Multi-Functional Silica Nanoparticles Based on Metal Atom Clusters: From Design to Toxicological Studies

2014 ◽  
Vol 617 ◽  
pp. 179-183
Author(s):  
Tangi Aubert ◽  
Nicolas Nerambourg ◽  
Chrystelle Neaime ◽  
Francisco Cabello-Hurtado ◽  
Marie Andrée Esnault ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Metal Atom ◽  
Risk Evaluation ◽  
Human Cells ◽  
Hybrid Nanoparticles ◽  
Gold Nanocrystals ◽  
Atom Clusters ◽  
Toxicological Studies ◽  
Potential Applications

We report on the interest of luminescent and nanosized metal atom clusters for the development of functional silica nanoparticles. Furthermore, multi-functional hybrid nanoparticles have been achieved by associating these luminescent clusters with magnetic γ-Fe2O3 nanocrystals and plasmonic gold nanocrystals. In addition, as part of the risk evaluation before potential applications, the toxicity of the nanoparticles was evaluated both on plants and on human cells.

scholarly journals Time-gated luminescence bioimaging with new luminescent nanocolloids based on [Mo6I8(C2F5COO)6]2−metal atom clusters

2016 ◽  
Vol 18 (43) ◽  
pp. 30166-30173 ◽  
Author(s):  
Chrystelle Neaime ◽  
Maria Amela-Cortes ◽  
Fabien Grasset ◽  
Yann Molard ◽  
Stéphane Cordier ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Metal Atom ◽  
Atom Clusters

Functional silica nanoparticles based on metal atom clusters for time gated luminescence biotechnology applications.

scholarly journals Altered Gene Transcription in Human Cells Treated with Ludox® Silica Nanoparticles

2014 ◽  
Vol 11 (9) ◽  
pp. 8867-8890 ◽  
Author(s):  
Caterina Fede ◽  
Caterina Millino ◽  
Beniamina Pacchioni ◽  
Barbara Celegato ◽  
Chiara Compagnin ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Gene Transcription ◽  
Human Cells ◽  
Altered Gene

scholarly journals Mesoporous Silica Nanoparticles: Their Projection in Nanomedicine

2012 ◽  
Vol 2012 ◽  
pp. 1-20 ◽  
Author(s):  
María Vallet-Regí
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Surrounding Medium ◽  
Stimuli Responsive ◽  
Guest Molecules ◽  
Different Types ◽  
Potential Applications ◽  
Inorganic Nanomaterials

Mesoporous silica nanoparticles are receiving growing attention by the scientific biomedical community. Among the different types of inorganic nanomaterials, mesoporous silica nanoparticles have emerged as promising multifunctional platforms for nanomedicine. Since their introduction in the drug delivery landscape in 2001, mesoporous materials for drug delivery are receiving growing scientific interest for their potential applications in the biotechnology and nanomedicine fields. The ceramic matrix efficiently protects entrapped guest molecules against enzymatic degradation or denaturation induced by pH and temperature as no swelling or porosity changes take place as a response to variations in the surrounding medium. It is possible to load huge amounts of cargo into the mesopore voids and capping the pore entrances with different nanogates. The application of a stimulus provokes the nanocap removal and triggers the departure of the cargo. This strategy permits the design of stimuli-responsive drug delivery nanodevices.

Formation of polyoxazoline-silica nanoparticles via the surface-initiated cationic polymerization of 2-methyl-2-oxazoline

2016 ◽  
Vol 7 (32) ◽  
pp. 5157-5168 ◽  
Author(s):  
G. Bissadi ◽  
R. Weberskirch
Keyword(s):  
Silica Nanoparticles ◽  
Cationic Polymerization ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Hybrid Nanoparticles ◽  
Cationic Ring Opening Polymerization ◽  
Silica Hybrid

The fabrication of silica hybrid nanoparticles by a surface-initiated cationic ring-opening polymerization of poly(2-methyl-2-oxazoline)s has been described.

scholarly journals Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field

Materials ◽  
2019 ◽  
Vol 12 (8) ◽  
pp. 1206 ◽  
Author(s):  
Kun Nie ◽  
Xiang Yu ◽  
Navnita Kumar ◽  
Yihe Zhang
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Multilayer Films ◽  
Layer By Layer ◽  
Guest Molecules ◽  
Potential Applications ◽  
Spatio Temporal ◽  
Release Speed

A viable short FITC-peptide immobilization is the most essential step in the fabrication of multilayer films based on FITC-peptide. These functional multilayer films have potential applications in drug delivery, medical therapy, and so forth. These FITC-peptides films needed to be handled with a lot of care and precision due to their sensitive nature. In this study, a general immobilization method is reported for the purpose of stabilizing various kinds of peptides at the interfacial regions. Utilizing Mesoporous silica nanoparticles can help in the preservation of these FITC-peptides by embedding themselves into these covalently cross-linked multilayers. This basic outlook of the multilayer films is potent enough and could be reused as a positive substrate. The spatio-temporal retention property of peptides can be modulated by varying the number of capping layers. The release speed of guest molecules such as tyrosine within FITC-peptide or/and adamantane (Ad)-in short peptides could also be fine-tuned by the specific arrangements of the multilayers of mesoporous silica nanoparticles (MSNs) and hyaluronic acid- cyclodextrin (HA-CD) multilayer films.

scholarly journals Polyvinylpyrrolidone Nanofibers Encapsulating an Anhydrous Preparation of Fluorescent SiO2–Tb3+ Nanoparticles

Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 510 ◽  
Author(s):  
Jianhang Shi ◽  
Yanxin Wang ◽  
Linjun Huang ◽  
Peng Lu ◽  
Qiuyu Sun ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Optical Properties ◽  
Hybrid Nanoparticles ◽  
Hybrid Nanofibers ◽  
Transmission Electron ◽  
Potential Applications ◽  
Composition Structure ◽  
Photoluminescent Materials ◽  
Influence Of Ph

A novel anhydrous preparation of silica (SiO2)-encapsulated terbium (Tb3+) complex nanoparticles has been investigated. The SiO2-Tb3+ nanoparticles are incorporated in electrospun polyvinylpyrrolidone hybrid nanofibers. Transmission electron microscopy confirms that Tb3+ complexes are uniformly and stably encapsulated in or carried by nanosilica. The influence of pH on the fluorescence of Tb3+ complexes is discussed. The properties, composition, structure, and luminescence of the resulting SiO2–Tb3+ hybrid nanoparticles are investigated in detail. There is an increase in the fluorescence lifetime of SiO2–Tb3+ nanoparticles and SiO2–Tb3+/polyvinylpyrrolidone (PVP) hybrid nanofibers compared with the pure Tb3+ complexes. Due to the enhanced optical properties, the fluorescent hybrid nanofibers have potential applications as photonic and photoluminescent materials.

Electronic Structure and Spectra of Niobium Metal Atom Clusters

1968 ◽  
Vol 48 (2) ◽  
pp. 843-851 ◽  
Author(s):  
Robert F. Schneider ◽  
Raymond A. Mackay
Keyword(s):  
Electronic Structure ◽  
Metal Atom ◽  
Atom Clusters
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