Research Progress of N-Alkylation of Alcohol and Amine by "Hydrogen Reaction"
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Amine compounds are widely found in natural products, pharmaceuticals and fine chemical products. Therefore, it is of great significance to develop methods for synthesizing amine compounds. Therefore, in recent years, a new method of synthesizing amines has been developed, namely "hydrogen borrowing reaction". This article reviews the alkylation of primary alcohols and amines, the cyclization of amino alcohols to form N-heterocyclic compounds, the reaction of diols and amines to form N-heterocyclic compounds, the reaction of alcohols and sulfonamides, and the reaction of alcohols and amines containing N heteroatoms , Alcohol and ammonia gas and ammonia to produce amine by hydrogen reaction research progress.
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1954 ◽
Vol 2
(4)
◽
pp. 655-667
2021 ◽
Vol 2021
◽
pp. 1-11
2021 ◽
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