Acute intermittent porphyria: a nursing case study

1995 ◽  
Vol 15 (6) ◽  
pp. 35-39
Author(s):  
SS Resor ◽  
PG Beare
Keyword(s):  
Nursing Care ◽  
Complex Disease ◽  
Acute Intermittent Porphyria ◽  
Signs And Symptoms ◽  
Genetic Transmission ◽  
Life Saving

Nursing care for a patient with AIP can be challenging. AIP is a complex disease with various signs and symptoms and is often misdiagnosed. Recognition of the signs and symptoms of AIP could be life-saving. Ways to avoid exacerbations, as well as counseling regarding possible genetic transmission, are important aspects of the nursing care of individuals with AIP.

Sternal wound infection: a case study of a devastating postoperative complication

1998 ◽  
Vol 18 (1) ◽  
pp. 31-35 ◽  
Author(s):  
LC Hussey ◽  
B Leeper
Keyword(s):  
Risk Factors ◽  
Antibiotic Therapy ◽  
Wound Infection ◽  
Postoperative Complication ◽  
Nursing Care ◽  
Signs And Symptoms ◽  
Sternal Wound Infection ◽  
Telemetry Unit ◽  
Discharge Teaching

Patients with a sternal wound infection are often admitted to the ICU or to a telemetry unit. The case of MW is extreme; most patients with a sternal wound infection can be successfully treated with antibiotic therapy and debridement. However, this case illustrates what devastating effects a sternal wound infection can have and the importance of nursing care and prevention. Nurses have a key role in minimizing the severity of sternal wound infection by being aware of the risk factors and providing thorough discharge teaching to patients so that signs and symptoms are reported early.

Identification of Antineoplastic Targets with Systems Approaches, Using Resveratrol as an In-Depth Case Study

2017 ◽  
Vol 23 (32) ◽  
pp. 4773-4793 ◽  
Author(s):  
Nivedita Singh ◽  
Sherry Freiesleben ◽  
Olaf Wolkenhauer ◽  
Yogeshwer Shukla ◽  
Shailendra K. Gupta
Keyword(s):  
Drug Target ◽  
Complex Disease ◽  
Biological Targets ◽  
Systems Approaches ◽  
Anticancer Mechanism ◽  
Genetic And Environmental Factors ◽  
Key Steps ◽  
Network Approaches ◽  
Novel Drug

The identification and validation of novel drug–target combinations are key steps in the drug discovery processes. Cancer is a complex disease that involves several genetic and environmental factors. High-throughput omics technologies are now widely available, however the integration of multi-omics data to identify viable anticancer drug-target combinations, that allow for a better clinical outcome when considering the efficacy-toxicity spectrum, is challenging. This review article provides an overview of systems approaches which help to integrate a broad spectrum of technologies and data. We focus on network approaches and investigate anticancer mechanism and biological targets of resveratrol using reverse pharmacophore mapping as an in-depth case study. The results of this case study demonstrate the use of systems approaches for a better understanding of the behavior of small molecule inhibitors in receptor binding sites. The presented network analysis approach helps in formulating hypotheses and provides mechanistic insights of resveratrol in neoplastic transformations.

scholarly journals Application of Levine’s Model in Nursing Care of Patient with Diabetic Foot: A Case Study

2020 ◽  
Vol 4 (1) ◽  
pp. 6
Author(s):  
Ida Ayu Agung Laksmi ◽  
Heri Kristianto ◽  
Tony Suharsono
Keyword(s):  
Nursing Care ◽  
Diabetic Foot ◽  
Single Case ◽  
Hemodynamic Instability ◽  
Design Data ◽  
Tissue Integrity ◽  
Damage Tissue ◽  
Conservation Problem ◽  
Conservation Model

Diabetic foot is such a life threatening condition for people with Diabetes Mellitus which it can be result in hemodynamic instability and loss of consciousness. In order to improve quality of nursing care in patient with diabetic foot, nurses should apply a nursing model approach. Levine conservation theoretical model is one of comprehensive model theory that can be applied in patients with critical diabetic foot in Emergency Department (ED). This case study describes a nursing care using Levine's Conservation Model to care for a patient with diabetic foot.  This study was a case study with a single case design. Data were collected using physical assessment, written communications with the patient, interviews patient family members, and observing the patient during intensive care in the ED of Lawang General Hospital on December 21th, 2015. Levine's Conservation Model used as the nursing guideline successfully identified patient issues including ineffective breathing pattern as a major priority of energy conservation problem and damage tissue integrity as a problem of structural conservation. Both of conservation problem were caused by patient's personal integrity conservation maladaptive that caused by ineffective therapeutic regimen management. Levine’s conservation model is useful to investigate nursing problem and applicable to solve the emergency condition of damage tissue integrity in patients with diabetic foot. Index Terms— diabetic foot, nursing care, levine’s conservation model.

scholarly journals Biochemical and hematological analysis in acute intermittent porphyria (AIP): a case report

2013 ◽  
Vol 85 (3) ◽  
pp. 1207-1214 ◽  
Author(s):  
ANNA R.R. DOS SANTOS ◽  
RAFAELA R. DE ALBUQUERQUE ◽  
MARIA J.R. DORIQUI ◽  
GRACIOMAR C. COSTA ◽  
ANA PAULA S.A. DOS SANTOS
Keyword(s):  
Biochemical Parameters ◽  
Contraceptive Use ◽  
Aminolevulinic Acid ◽  
Neuropsychiatric Symptoms ◽  
Acute Intermittent Porphyria ◽  
Signs And Symptoms ◽  
Acute Porphyria ◽  
Reactive Protein ◽  
Hematological Analysis ◽  
Hematological And Biochemical Parameters

Acute intermittent porphyria is the most common acute porphyria caused by a decrease in hepatic porphobilinogen deaminase activity, resulting in an accumulation of delta-aminolevulinic acid and porphobilinogen. This disease shows nonspecific signs and symptoms that can be confused with other diseases, thereby making the diagnosis difficult. We report a case of acute intermittent porphyria, reviewing clinical and laboratory aspects, highlighting the hematological and biochemical parameters during and after the crisis. A female patient, aged 28 years, suffered two crises, both presenting gastrointestinal disorders. The second presented neuropsychiatric symptoms. The analysis of hematological and biochemical parameters during the second crisis showed anemia, leukocytosis, hyponatremia, mild hypokalemia, uremia and elevated C-reactive protein. The initial treatment included glucose infusion, a diet rich in carbohydrates and interruption of porphyrinogenic drugs. Subsequently, treatment was maintained with oral contraceptive use. According to the observed data, signs and symptoms of gastrointestinal, neurological and psychiatric disorders, associated with laboratory results presented in this paper can be applied to screen acute porphyria, contributing to early diagnosis.

Penerapan Activity Daily Living (ADL) Makan Terhadap Tingkat Kemandirian Pada Pasien Skizofrenia Dengan Defisit Perawatan Diri Makan

2021 ◽  
Vol 1 ◽  
pp. 1542-1552
Author(s):  
Intan Cahyani ◽  
Ramadhan Putra Satria ◽  
Puji Suhiro
Keyword(s):  
Nursing Care ◽  
Daily Living ◽  
Self Care ◽  
Descriptive Study ◽  
Narrative Form ◽  
Case Study Approach ◽  
Study Approach ◽  
The Third ◽  
Care Deficit

AbstractFeeding self-care deficit is a person's inability to perform eating activities according to the proper way of eating. Activity Daily Living (ADL) therapy is one of the therapies claimed to be able to increase the patient's independence in improving how to eat. To apply Activity Daily Living (ADL) in patients with feeding self-care deficit to increase self-feeding independence. The research was a descriptive study with a case study approach conducted in the working area of Puskesmas Dukuhwaru, Tegal Regency. It was carried out on 15-17 February 2021. Data were obtained through interviews, observation and physical examination and presented in narrative form. After performed the intervention for 3 days, the results showed an increase in self-feeding independence in both subjects. It described at the third day of the research. Patients with nursing problems of feeding self-care deficit are recommended to provide ADL to increase the patient's independence. Keywords: Activity Daily Living (ADL); Feeding Self-Care Deficit; Mental Nursing Care AbstrakDefisit Perawatan Diri Makan merupakan ketidakmampuan seseorang dalam melakukan aktivitas makan sesuai tata cara makan yang benar. Terapi Activity Daily Living (ADL) menjadi salah satu terapi yang diyakini mampu meningkatkan kemandirian pasien dalam meningkatkan cara makan. Dapat menerapkan terapi Activity Daily Living (ADL) pada pasien defisit perawatan diri makan untuk meningkatkan kemandirian makan. Peneliti ini merupakan penelitian deskriptif dengan pendekatan studi kasus, lokasi studi kasus di Wilayah Puskesmas Dukuh waru Kabupaten Tegal dilakukan tanggal 15-17 Februari 2021, data diperoleh melalui wawancara, observasi dan pemeriksaan fisik. data disajikan dalam bentuk naratif. Setelah dilakukan intervensi selama 3 hari didapatkan hasil adanya peningkatkan makan pada kedua subjek penelitian yaitu dari ketergantungan makan pada awal pengkajian menjadi setelah selesai makan pada hari ketiga penelitian. Pasien dengan masalah keperawatan defisit perawatan diri makan dianjurkan untuk memberikan terapi Activity Daily Living (ADL) untuk meningkatkan kemandirian pasien dalam meningkatkan kemandirian.Kata Kunci: Activity Daily Living (ADL); Asuhan Keperawatan Jiwa; Defisit Perawatan Diri Makan

scholarly journals Esophageal Perforation with Unilateral Fluidothorax Caused by Nasogastric Tube

2016 ◽  
Vol 2016 ◽  
pp. 1-2
Author(s):  
Lukas P. Mileder ◽  
Martin Müller ◽  
Friedrich Reiterer ◽  
Alexander Pilhatsch ◽  
Barbara Gürtl-Lackner ◽  
...  
Keyword(s):  
Nasogastric Tube ◽  
Esophageal Perforation ◽  
Signs And Symptoms ◽  
Feeding Tube ◽  
Tube Placement ◽  
Nasogastric Feeding ◽  
Medical Interventions ◽  
Life Saving ◽  
Diagnostic Approaches ◽  
Nasogastric Tube Placement

Preterm infants are highly susceptible to injuries following necessary and often life-saving medical interventions. Esophageal perforation is a rare, yet serious complication that can be caused by aerodigestive tract suction, endotracheal intubation, or nasogastric tube placement. We present the case of a neonate born at 23 weeks plus three days of gestation with chest radiography showing malposition of the nasogastric feeding tube and massive right-sided effusion of Iopamidol in the pleural cavity due to esophageal perforation. In addition, the article summarizes common signs and symptoms associated with esophageal perforation in infants and discusses diagnostic approaches.

scholarly journals Care and management of bisphosphonate-associated osteonecrosis of jaw in patient with pathological fracture of mandible: case study

2019 ◽  
Vol 3 (23) ◽  
pp. 34-36
Author(s):  
M. V. Kirpichnikov ◽  
V. V. Podolsky ◽  
E. N. Yarygina ◽  
A. S. Serbin ◽  
K. A. Aleshanov
Keyword(s):  
Pathological Fracture ◽  
Signs And Symptoms ◽  
Osteonecrosis Of Jaw ◽  
Intravenous Bisphosphonates

This is a case study of patient with bisphosphonate associated osteonecrosis of the mandible after an extraction of teeth 4.6 and 4.7 complicated with pathological fracture while receiving intravenous bisphosphonates is discussed. The patients presenting signs and symptoms are reviewed. Bisphosphonates induced osteonecrosis definition and are reviewed management.

scholarly journals EFFECT OF PERINEAL REPAIR AND MUSHAKADI TAILA MATRABASTI IN MANAGEMENT OF RECTAL PROLAPSE (GUDABHARMSA): A CASE STUDY

2020 ◽  
Vol 8 (8) ◽  
pp. 4267-4270
Author(s):  
Sapna Maheshwari ◽  
Harshit Shah ◽  
Pragnesh Patel
Keyword(s):  
Rectal Prolapse ◽  
Signs And Symptoms ◽  
Cost Effective ◽  
Complete Rectal Prolapse ◽  
Full Thickness ◽  
Perineal Repair ◽  
Chief Complaints ◽  
Surgical Options ◽  
External Rectal Prolapse

Rectal prolapse can present in a variety of forms and is associated with a range of symptoms including pain, incomplete evacuation, bloody and/or mucous rectal discharge, and fecal incontinence or constipa-tion. Complete external rectal prolapse is characterized by a circumferential, full-thickness protrusion of the rectum through the anus, which may be intermittent or may be incarcerated and poses a risk of strangu-lation. There are multiple surgical options to treat rectal prolapse, and thus care should be taken to under-stand each patient’s symptoms, bowel habits, anatomy, and pre-operative expectations. We propose an al-gorithm based on available outcomes data in the literature, an understanding of ano-rectal physiology, and expert opinion that can serve as a guide to determining the rectal prolapse operation that will achieve the best possible postoperative outcomes for individual patients. Mushakadi Taila Matrabasti will be given in Sushrut Samhita as a treatment1 with perineal repair. So, it is really needed to find a safe, easier, less com-plicating, cost effective and fruitful approach for the management of disease through Ayurveda. A 62year old male patient came to the hospital with chief complaints of protrusion of mass from the anus with mu-cous discharge, constipation since last 5 years. He was diagnosed as complete rectal prolapse. Considering the signs and symptoms of rectal prolapse, the treatment of rectal prolapsed was planned with perineal re-pair and Mushakadi Taila Matarabasti as per mentioned in the treatment of Gudabhransha by Aacharya Sushruta.

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