scholarly journals Computed tomography severity scoring of COVID 19 infected young patients: Is the second wave affecting the young lungs more than the first wave in India?

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Omair Shah ◽  
Shadab Maqsood ◽  
Tahleel Shera ◽  
Mudasir Bhat ◽  
Naseer Choh ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Severity Score ◽  
Young Patients ◽  
Severity Scoring ◽  
Number Of Patients ◽  
Severity Scores ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Second Wave

We evaluated the High Resolution Computed Tomography (HRCT) findings in young patients (< 40 years) infected with the COVID 19 virus and tried to find out any difference in the severity of lung involvement between the first and second wave of the pandemic and whether the notion of young population being more severely affected by the second wave holds true.Two-hundred (200) young patients (<40 years) with RT PCR documented COVID infections undergoing HRCT chest at our institute were included. Group A included young patients infected in the first wave (up to 28 February 2021) while Group B included patients beyond this date. Demographic and clinical data was obtained from the medical records department. HRCT scans were retrieved from the archive and were assessed by two radiologists or CT severity scoring. The mean severity scores were calculated and any statistical difference between Group A and B was sought. CT scans of four fully vaccinated patients were also evaluated.The age and gender distribution among the two groups was comparable. A greater number of patients in group B required hospital admission compared to group A (74% VS 53%). In group A, the mean severity score was 10.1±2.1 with 34 patients (34%) in mild category, 46 patients (46%) in moderate group and 20 patients (20%) in the severe group. In group B, the mean CT severity score was 12.6±2.3 with 20 patients (20%) in mild category, 42 patients (42%) in moderate group and 38 patients (38%) in the severe group.Lung involvement in young patients in the second wave is more severe requiring more hospital admissions. Vaccinated population may well have a milder form of the disease.

scholarly journals INTRAVENOUS REGIONAL ANESTHESIA (BIERS BLOCK);

2012 ◽  
Vol 19 (05) ◽  
pp. 710-714
Author(s):  
Muhammad ASGHER ◽  
ASIM GHAURI ◽  
MUHAMMAD ABDULLAH ◽  
Tariq Abassi
Keyword(s):  
Regional Anaesthesia ◽  
Military Hospital ◽  
P Value ◽  
Complete Evaluation ◽  
Intravenous Regional Anesthesia ◽  
Number Of Patients ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Intravenous Regional Anaesthesia

Objective: To compare the analgesic effects of combination of 0.5% Lidocaine plus Ketorolac in intravenous regionalanaesthesia technique with those of Lidocaine (0.5%) alone to prevent post operative pain after intravenous regional anaesthesia (Biersblock). Study design: Randomized Control Trial. Place and duration of study: The study was carried out at Department of Anaesthesiology,Intensive Care and pain management, Combined Military hospital, Rawalpindi from July 2008 to February 2009. Patients and Methods: Thestudy was conducted after complete evaluation of risk / benefit ratio to the patients. On the basis of random number method the patients weredivided into two equal groups (group A and group B). The number of patients in each group was 75. Group A was assigned Lidocaine in a dose of200mg 40ml of 0.5% solution and group B was assigned injection Ketorolac 30mg added to Lidocaine in a dose of 200mg 40ml of 0.5% solution.The patients were kept in post anaesthesia care unit for two hours and pain intensity was measured by visual analogue scale(VAS) on 15,30minutes,1hour, 1.5 and at 2 hours after the cuff deflation. The analgesic efficacy recorded on the basis of visual analog scale of two groups, wascompared using student’s t - test. p value of less than 0.05 was considered statistically significant. Results: In group A 33 males and 42 femaleswere enrolled for the study while in group B there were 38 males and 37 females. The mean age of the patients in group A was 34.31 ± 6.03years while in group B was 32.99 ± 6.08 years. Patients were also classified according to ASA classification in which 87 patients were classifiedas ASA – I and 63 patients as ASA – II. Group B which received Ketorolac in addition to Lidocaine for Bier’s block had low visual analogue scoresas compared to group A which received only Lidocaine for Bier’s block. P values obtained after the comparison of the mean VAS of two groupsat 15 minutes, 30 minutes, 1 hour, 1.5 hours and 2 hours were all less than 0.05 (0.002 for 15 minutes, 0.004 for 30 minutes, 0.001 for 1 hour,0.004 for 1.5 hours and 0.001 for 2 hours). Conclusions: Ketorolac improves the postoperative analgesia markedly when used with Lidocainein intravenous regional anaesthesia.

scholarly journals Conventional treatment versus vacuum therapy for diabetic foot ulcers treatment

2017 ◽  
Vol 5 (1) ◽  
pp. 49 ◽  
Author(s):  
Vigna Sai Potula
Keyword(s):  
Therapy Group ◽  
Vacuum Therapy ◽  
College Hospital ◽  
Medical College ◽  
Randomized Controlled ◽  
Number Of Patients ◽  
Group A ◽  
Randomized Controlled Trail ◽  
The Mean ◽  
Group B

Background: This study compares the efficacy of vacuum therapy against conventional iodine povidone dressing with respect to area and time of ulcer.Methods: This study is a randomized controlled trail which was conducted in Meenakshi Medical College hospital and research institute Enathur Kanchipuram. The number of patients selected were 50, which were divided into 2 groups, Group A which consisted of 25 and received vacuum therapy, Group B which consisted of 25 and received povidone-iodine solution.Results: This study was a 16 days study, mean area of ulcer on day 0 was 11.25 cm2 in group B, 10.89 cm2 in group A. On day 6, mean area of ulcer was 10.44 cm2 in group B, 8.98 cm2 in group A. Mean area of ulcer was 10.39 cm2 in group B, 7.66 cm2 in group A on the end of the day 16. The results show that both the groups showed decrease in the area of ulcers, but patients in group A who underwent vacuum therapy have shown greater decrease in the mean area of ulcer. The decrease in surface area of ulcer was statistically significant i.e. p=0.025. There was a greater decrease in infection in group A on 16th day compared to group A on 16th day. On day 0, 48% and 60% growth of microorganisms was observed in patients of group B and group A respectively (p=0.428). On day 16, 28% and 8% growth of microorganisms was observed in patients of group B and group A respectively (p=0.034).Conclusions: Vacuum therapy was more effective compared to conventional method of povidone-iodone solution dressing in rate of healing and time of healing.

372 ESOPHAGEAL BODY PERISTALSIS CORRELATES FOR DYSPHAGIA AND REGURGITATION: AN ASSESSMENT BASED ON BARIUM ESOPHAGRAM

2020 ◽  
Vol 33 (Supplement_1) ◽  
Author(s):  
L Giulini ◽  
D Razia ◽  
S Mittal
Keyword(s):  
Clinical Symptoms ◽  
Objective Assessment ◽  
Esophageal Peristalsis ◽  
High Resolution Manometry ◽  
Number Of Patients ◽  
Barium Esophagram ◽  
Group A ◽  
The Mean ◽  
Definition Of ◽  
Group B

Abstract   Because it offers real-time assessment, barium esophagram should be the modality of choice when studying esophageal peristalsis. However, no standard reporting method is available for BE results. Presently, peristaltic disorders are defined according to high-resolution manometry (HRM), but HRM findings do not correlate with clinical symptoms. The aim of this study was to stratify esophageal peristaltic function via standardized evaluation of BE, and to define the association between esophageal peristalsis and dysphagia and regurgitation. Methods After IRB approval, a prospectively maintained database was reviewed for patients who underwent both HRM and BE from 08/01/2016 to 12/31/2019. Patients with conditions associated with outflow impairment were excluded. BEs were re-examined in blinded fashion and assigned subjective scores (0, 1, or 2) for dilation grade (DG) and contractility grade (CG). Patients were categorized according to the sum of the DG and CG: Group A = 0, Group B = 1–2, and Group C = 3–4. Mean distal contractile integral (DCI), number of failed contractions on HRM, and number of patients with dysphagia/regurgitation in each group were analyzed and compared. Results In all, 124 patients were included. The mean DCI (mmHg*cm*s) was 2539.1 ± 1357.8 in Group A, 884.4 ± 916.9 in Group B, and 77.4 ± 192.3 in Group C (p &lt; 0.001). The mean number of failed contractions were 0.7 ± 1.3, 3.4 ± 3.4, and 8.6 ± 3.2, respectively (p &lt; 0.001). Table 1 shows the distribution of patients with dysphagia or regurgitation across groups. The proportion of patients with dysphagia in Group C was higher than in Groups A or B (OR 3.75, p = 0.02; and OR 2.58, p = 0.07, respectively). Similarly, Group C was significantly more often associated with regurgitation than in Groups A or B (OR 4.69, p = 0.009; and OR 4.42, p = 0.005). Conclusion The combined DG and CG allowed us to identify the patients with a grade of peristaltic disfunction that was significantly more associated with dysphagia or regurgitation (Group C). However, in order to achieve a clearer definition of the different peristaltic disfunction levels according to their propensity to cause dysphagia or regurgitation, a more objective assessment of both DG and CG should be provided; therefore, further studies are required.

scholarly journals Changes in the management of patients with severe acute pancreatitis

2008 ◽  
Vol 45 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Tercio De Campos ◽  
Candice Fonseca Braga ◽  
Laíse Kuryura ◽  
Denise Hebara ◽  
José Cesar Assef ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Apache Ii ◽  
Specific Approach ◽  
Severe Pancreatitis ◽  
Group A ◽  
The Mean ◽  
Fluid Collections ◽  
Group B

BACKGROUND: Severe acute pancreatitis is present in up to 25% of patients with acute pancreatitis, with considerable mortality. Changes in the management of acute pancreatitis in the last 2 decades contributed to reduce the mortality. AIM: To show the evolution in the management of severe acute pancreatitis, comparing two different approaches. METHODS: All patients with severe acute pancreatitis from 1999 to 2005 were included. We compared the results of a retrospective review from 1999 to 2002 (group A) with a prospective protocol, from 2003 to 2005 (group B). In group A severe pancreatitis was defined by the presence of systemic or local complications. In group B the Atlanta criteria were used to define severity. The variables analyzed were: age, gender, etiology, APACHE II, leukocytes, bicarbonate, fluid collections and necrosis on computed tomography, surgical treatment and mortality. RESULTS: Seventy-one patients were classified as severe, 24 in group A and 47 in group B. The mean APACHE II in groups A and B were 10.7 ± 3.5 and 9.3 ± 4.5, respectively. Necrosis was seen in 12 patients (50%) in group A and in 21 patients (44.7%) in group B. Half of the patients in group A and two (4.3%) in group B underwent to pancreatic interventions. Mortality reached 45.8% in group A and 8.5% in group B. CONCLUSION: A specific approach and a prospective protocol can change the results in the treatment of patients with severe acute pancreatitis.

scholarly journals ROLE OF IVERMECTIN, DOXYCYCLINE ALONG WITH SUPPORTIVE CARE IN TREATMENT OF COVID-19 POSITIVE CHILDREN (>9 YEAR) AND ADOLESCENT AGE GROUP A PROSPECTIVE OBSERVATIONAL STUDY FROM TERTIARY CARE CENTER OF WESTERN U.P

2021 ◽  
Vol 9 (06) ◽  
pp. 307-314
Author(s):  
Nidhi Singh ◽  
◽  
Yogesh Goel ◽  
Ritu Agarwal ◽  
◽  
...  
Keyword(s):  
Supportive Care ◽  
Tertiary Care ◽  
Group Method ◽  
Control Group ◽  
Age Group ◽  
Number Of Patients ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Mean Time

Background: In December 2019, the infection caused by 2019 novel coronavirus led to an outbreak in Wuhan, situated in the Hubei Province of China. The number of studies on children with COVID-19 is limited. We reviewed that COVID-19 does indeed affect children the same way as any other age group. Children can act as carriers of the virus and can endanger the lives of other individuals. Aim: In this Prospective study a combination of Ivermectin, Doxycycline along with supportive care was evaluated therapeutically to treat COVID-19 children (> 9 year) and adolescent age group. Method: Study was performed on pediatric COVID-19 patient who were enrolled in this study with a predefined inclusion and exclusion criteria. RT- PCR of the SERS-CoV-2 was done. The clinical features and response to treatment were noted according to protocol. Patients were divided in 2 groups.Combination of Ivermectin, Doxycycline and supportive treatment were given in one group and other group acted as control. Retesting was done between 5 to 25 days of starting medication. Result: In the study after excluding 50 patients, out of remaining 110 patients, males and females were 67 and 43 respectively, the age ranged between 9-18 years (Mean age was 10.88 ± 2.39 year). Retesting was done between 5 to 25 days of starting medication. Symptomatic improvement was noticed after 2-3 days of starting medication. Mean recovery time in Ivermectin-Doxycycline-supportive care group (Group B) was 10.28±4.72 versus 14.92±8.40 in control group. Hence, using Ivermectin along with Doxycycline reduced mean time to recovery up to 4.64 days. By analyzing the mean time to recovery in mild, moderate and severe patients in each group, it was shown that the mean time to recovery in Group B was 6.88±1.84,11.78±1.81, 21.28±1.79 days, respectively vs 8.375±1.25, 12.76±1.73, 23.16±1.47 days respectively in Group A. All patients symptomatically improved and tested negative. No death was noted in either group. Conclusion: Most of the cases of SARS-CoV-2 were mild and did not require specific treatment but combination of Ivermectin and Doxycycline along with supportive care was found to be effective in early viral clearance and helped the patients to overcome the disease early. Early improvement of symptoms and early discharge were noted in patients whom we gave combination of medicines. Over all it is a very cheap combination, save a lot of lives, and very helpful for resource-poor settings. This study has limitations as our number of patients was small.

scholarly journals Methotrexate plus narrow band ultraviolet B (NBUVB) versus methotrexate alone in the treatment of moderate to severe plaque psoriasis: A randomized clinical trial

2016 ◽  
Vol 13 (1) ◽  
pp. 12-23 ◽  
Author(s):  
Dhan Keshar Khadka ◽  
S Agrawal ◽  
T K Dhali
Keyword(s):  
Plaque Psoriasis ◽  
Negative Impact ◽  
Ultraviolet B ◽  
Plaque Type ◽  
Number Of Patients ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B

Introduction: Psoriasis is a chronic, recurring inflammatory disease affecting the skin, joints and nails that has a significant negative impact on the quality of life. Efficacy of combination of methotrexate/narrowband ultraviolet B (NBUVB) phototherapy in the treatment of psoriasis has been rarely assessed. Objectives: To compare the therapeutic efficacy of methotrexate plus NBUVB phototherapy combination vs.  methotrexate  in  the  treatment  of  moderate  to  severe  chronic  plaque  psoriasis. Material and methods: Seventy-nine patients with chronic plaque-type psoriasis (body surface area involvement >2%) were randomized to receive either methotrexate/NBUVB phototherapy (group A) or methotrexate (group B). End point of treatment was 75% reduction in Psoriasis Area and Severity Index (PASI75) Score or up to 12weeks, whichever was earlier. Patients were then followed up for a period of 12 weeks for assessment of adverse effect, DLQI and relapse.Results: Of 79 patients, 69 completed the treatment period and follow-up. PASI 75 was achieved in 35/39(89%) patients in group A and 34/40(85%) patients in group B (P=0.052). The mean number of weeks (P = 0.031), the mean cumulative dose of NBUVB (8.2±3.5J/cm2)) and the mean number of phototherapy sessions (12±3)) required to achieve PASI 75 were less in group A compared with group B. There was no significant difference in the number of patients who relapsed during the follow- up period (P = 0.68). Conclusion: Combination of methotrexate and NBUVB phototherapy provides more rapid clinical improvement compared with methotrexate monotherapy in the treatment for chronic plaque-type psoriasis.NJDVL Vol. 13, No. 1, 2015 Page: 12-23

Development of a Severity Score System for Thalassemia Syndromes

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 2225-2225
Author(s):  
Angela Vitrano ◽  
Antonella Meloni ◽  
Walter Addario Pollina ◽  
Mehran Karimi ◽  
Amal El-Beshlawy ◽  
...  
Keyword(s):  
Scoring System ◽  
Research Funding ◽  
Full Data ◽  
Data Set ◽  
Severity Scoring ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
First Diagnosis

Introduction Thalassemia Syndromes (TS) are a group of inherited haemoglobin disorders characterized by different phenotype severity falling among heterozygote state, no transfusion dependent thalassemia (NTDT) and transfusion dependent Thalassemia (TDT) (Graffeo et al, 2018; Taher & Saliba, 2017). Several factors, independently by genotype and globin chain unbalance, modulate the severity of ineffective erythropoiesis (Rivella et al, 2015). Considering the complexity of this pathophysiology, one tool to evaluate patients on an individual basis is needed. The aim of this study was to develop a severity scoring system with a view to initiate timely interventions that would prevent any further complications. Methods An International Health Repository (IHR) protocol was approved on May 25th, 2017 by the Italian Ethical Committee (EudraCT Code Numbers 2017-004457-17 and 143AOR2017). Subsequently, an International Working Group (IWG) on Thalassemia was formed and it met in Palermo, Italy, on September 15th and 16th, 2017. Indicators of phenotype severity thought to be most pertinent in defining disease severity were shared among the IWG based on their expertise as well as on expert opinion reported on literature. These data were collected and stored on IHR platform (www.sanitasicilia.eu/IWG ). In order to define the prognostic score (PS) a retrospective multicenter case-control study was carried ahead. Overall, clinical findings of 7910 patients who attended the IWG centres from 1976 to 2018 were collected (Tab. 1). The study was based on 5657 cases that developed complications and 2253 controls that didn't develop any complications. The term "patient" was used both for cases and for controls. The variables used for the scoring system development were reported in Table 2. The PS was built using a Conditional Logistic Regression Model (CLRM) (DW. Hosmer, Jr., 2013). The full data-set was split into two data-set containing Group A and Group B patients. Group A included transfused TDT and NTDT patients, while Group B included only no transfused NTDT patients. This was necessary because of the variable "age at first transfusion" was absent in no transfused patients. The two PS will refer as Score A and Score B, respectively. The Stata 12 (StataCorp, College Station, TX, USA) was used for all analyses. Results Overall, the analysis was performed on 5657 cases (2812 Females, age at follow up 34.7±12.9) with a mortality of 8.5% and 2253 controls (1136 Females, age at follow up 22.1±12.8) with a mortality of 1.9%. Table 3 shows complications and deaths in the full data set. Moreover, it even suggests, as single patient may have more than one complication and that the cardiac complications followed by the cancer and infection were the most common. Table 4 shows the statistically significant variables for the calculation of the score. The age of the patient and at first diagnosis, the mean Hb, AST, ALT and the Left Ventricular Ejection Fraction (LVEF) were the statistically significant variables at CLRM analysis, for the Group A. The formula for the Score A=1.1x(Age)+0.9x(Age at first diagnosis)+1.3x(Hb mean)+1.006x(AST)+1.02x(ALT)+ 0.9x(EF). The age of the patient, the mean Hb and the LVEF were the statistically significant variables at CLRM analysis for the Group B. The formula for the Score B= 1.05x(Age)+1.001x(Hb mean) +0.9x(EF). Finally, Table 5 shows the application of these formulas to the full data set, defining five well-distinguished prognostic categories (Very low, Low, Intermediate, High, Very high). Conclusions Following appropriate validation, we propose that the severity scoring system described here could be developed into a practical tool for widespread clinical application, not only to evaluate patient status and classify disease subgroups, but also to inform treatment decisions and monitor patient progress in response to therapy. Finally, the use of this scoring system may help to select appropriate candidate for innovative treatment. Disclosures Pepe: Chiesi Farmaceutici S.p.A., ApoPharma Inc., and Bayer: Other: No profit support. Vichinsky:bluebird bio: Consultancy, Research Funding; GBT: Consultancy, Research Funding; Pfizer: Consultancy, Research Funding; Novartis: Consultancy, Research Funding; Agios: Consultancy, Research Funding.

scholarly journals COMPARISON OF DURATION OF LABOUR BETWEEN PRIMIGRAVIDAS WITH AND WITHOUT AMNIOTOMY

1969 ◽  
Vol 3 (2) ◽  
pp. 379-382
Author(s):  
NAZIA LIAQAT ◽  
SAADIAYASMEEN ◽  
FARHAT NASIR ◽  
REHANA RAHIM.
Keyword(s):  
P Value ◽  
Stage Duration ◽  
Second Stage ◽  
Second Stage Of Labour ◽  
Number Of Patients ◽  
Group A ◽  
The Subject ◽  
The Mean ◽  
Group B ◽  
Duration Of Gestation

BACKGROUND: Amniotomy is a common and routine obstetrical procedure in many labour wards. It ismostly performed with the intention of accelerating the process of labour. The procedure is not risk free andthe results of various studies performed on the subject are diverse. The rationale of this study was to obtainconclusive evidence on the effect of amniotomy on the duration of labour and to establish protocols forlabour wards in the light of thatevidence.OBJECTIVES: To compare the duration of labour between primigravidas with and without amniotomy.METHODOLOGY: The total number of patients was 50 in each group; A and B who were subjected toamniotomy and no amniotomy respectively. Duration of First and Second stage of labour were noted andStudent T- test was applied to find the significance of difference in the duration of First and Second stages oflabour of the two groups. Data was analyzed using SPSS version 17.0.Results:: The mean ages of patients in Group A and B were 22.6+ 2.66 and 23± 2.03 years respectively (pvalue 0.647). The mean duration of gestation of Group A was 38.8+0.50 weeks and of Group B was 39.16 ±0.52 weeks (p value 0.0634). The duration of First Stage was 169+77 min in Group Aand 205+105 minutesin Group B (p value 0.2877). The Second stage duration was 78.6+45 in Group A and 72 ±32 minutes inGroup B (p value 0.6434).CONCLUSION: Amniotomy has no significant effect in shortening the duration of labour inprimigravidas.KEYWORDS: Amniotomy, Primigravidas, Labour

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

Age related volume of cadaver-prostates in Bangladesh

1970 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Rukshana Ahmed ◽  
Shamim Ara
Keyword(s):  
Prostate Gland ◽  
Age Groups ◽  
Clinical Settings ◽  
Cross Sectional ◽  
Medical College ◽  
Age Related ◽  
Group A ◽  
Key Words Prostate ◽  
The Mean ◽  
Group B

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77

Sign in / Sign up

Export Citation Format

Share Document