scholarly journals Pneumococcal sepsis associated with adrenal apoplexy in a young woman with anorexia nervosa

2013 ◽  
pp. 25-29
Author(s):  
Nicola Maria Vitola ◽  
Dante Lo Pardo ◽  
Romualdo Cirillo ◽  
Matteo De Roberto ◽  
Pier Giovanni Crocco ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Emergency Department ◽  
Anorexia Nervosa ◽  
Sudden Death ◽  
Clinical Picture ◽  
Causes Of Death ◽  
Critical Conditions ◽  
Crude Rate ◽  
Treatment Practices ◽  
Pneumococcal Sepsis

BACKGROUND A crude rate of mortality of 5% has been quoted for anorexia nervosa in recent studies. Nowadays the mechanism of death is unclear and various authors recommend that any anorexia nervosa death be reported and that, where possible, an autopsy be performed. METHODS In this work we present a case of sudden death in anorexia nervosa with unexpected autopsy findings. A 21-years-old woman with long-standing anorexia nervosa, severely underweight with a body mass index of 14.47 kg/m2, has been taken to the Emergency Department in very critical conditions. Despite the attempts of resuscitation, she died shortly afterwards. Therefore an autopsy has been requested in order to clarify the causes of death. RESULTS The clinical picture, laboratory parameters, histology and microbiological investigations were consistent with pneumococcal sepsis associated adrenal apoplexy. CONCLUSIONS The cause of death in anorexia nervosa cannot reliably be established from antemortem clinical features. All anorexia nervosa deaths should be reported together with description of necropsy. This may lead to advances in the knowledge and treatment practices.

scholarly journals Sudden death in children

2018 ◽  
Vol 146 (1-2) ◽  
pp. 55-62
Author(s):  
Aleksandra Doronjski ◽  
Milena Bjelica ◽  
Slobodan Spasojevic ◽  
Tanja Radovanovic ◽  
Jelena Culafic ◽  
...  
Keyword(s):  
Heart Failure ◽  
Emergency Department ◽  
Sudden Death ◽  
Causes Of Death ◽  
Carbon Monoxide Poisoning ◽  
Sudden Infant Death ◽  
Sudden Infant ◽  
Unexpected Death ◽  
Common Cause ◽  
Number Of Patients

Introduction/Objective. Sudden death in children may occur as a result of many diseases and accidents, while the cause often remains unknown. There are different terms in the literature that represent the causes of sudden death in children. The aim of our study was to determine the most common cause of sudden death in children admitted to the Clinic of Pediatrics. Methods. The retrospective study was conducted in the period from January 1, 1995 to December 31, 2015 and included 49 patients, aged from 10 days to 17 years, in whom death occurred in the Emergency Department and in the first 48 hours of hospitalization. Results. In 23 patients (47%) the cause of death was infection, in 10 patients (20%) heart failure, four patients (8%) died due to status epilepticus, the same number of patients (8%) died due to aspiration of a foreign body, while the rest of the patients died due to diabetic ketoacidosis (2%), rickets (2%), carbon monoxide poisoning (2%), hemolytic anemia (2%), suicide by hanging (2%), drowning (2%), sudden infant death syndrome (2%), and sudden unexpected death in epilepsy (2%). Most of the patients in our study were infants (43%). Conclusion. Our study shows that infants are at the highest risk of sudden death, while the most frequent causes of death are infections and cardiovascular diseases.

scholarly journals Hypokalemia-Induced Ventricular Tachycardia in a Patient with Anorexia Nervosa: A Case Report

2021 ◽  
Vol 7 (3) ◽  
pp. 1-4
Author(s):  
Yu-Wei Fang ◽  
Keyword(s):  
Emergency Department ◽  
Anorexia Nervosa ◽  
Ventricular Tachycardia ◽  
Case Report ◽  
Sudden Death ◽  
Sudden Change ◽  
General Weakness ◽  
Life Threatening

Sudden death is the main cause of mortality in patients with anorexia nervosa. Contribution form Life-threatening arrhythmia was highly suspected. Herein, we describe the case of a 20-year-old female who presented to the emergency department with general weakness and vertigo followed by sudden change in consciousness and syncope.

ACUTE FOREIGN BODY LARYNGO-TRACHEAL OBSTRUCTION: A CAUSE FOR SUDDEN AND UNEXPECTED DEATH IN CHILDREN

PEDIATRICS ◽  
1971 ◽  
Vol 48 (2) ◽  
pp. 281-285
Author(s):  
Felicien M. Steichen ◽  
Andrew Fellini ◽  
Arnold H. Einhorn
Keyword(s):  
Emergency Department ◽  
Foreign Body ◽  
Sudden Death ◽  
Clinical Picture ◽  
Sudden Unexpected Death ◽  
Cerebral Damage ◽  
Unexpected Death ◽  
Unexplained Death ◽  
Tracheal Obstruction ◽  
Foreign Body Obstruction

Sudden unexpected death in three well children beyond crib age due to laryngo-tracheal obstruction by a foreign body is described. The clinical picture is characterized by a paucity of clues in, very often, the absence of reliable witnesses and of any preexisting causes for sudden death. Because of this and on suspicion only, immediate laryngoscopy and bronchoscopy are indicated in all children above crib age with sudden unexpected and unexplained death, after initial respiratory and cardiac resuscitation have taken place. It is hoped that mouth to mouth breathing by the nonprofessional bystander as well as expertise with respiratory resuscitation by ambulance crews, will deliver the occasional child suffering from potentionally fatal foreign body obstruction of the airways to the emergency department before irreversible anoxic cerebral damage has occurred. Children treated in this optimal fashion may thus be given an opportunity to survive.

Anorexia Nervosa in an Elderly Woman

2001 ◽  
Vol 35 (2) ◽  
pp. 246-248 ◽  
Author(s):  
Rosalie Hill ◽  
Christopher Haslett ◽  
Shailesh Kumar
Keyword(s):  
Anorexia Nervosa ◽  
Depressive Symptoms ◽  
Electroconvulsive Therapy ◽  
Clinical Picture ◽  
Elderly Woman ◽  
Eating Behaviour ◽  
The Elderly ◽  
Aggressive Treatment ◽  
Comorbid Depression ◽  
First Onset

Objective: To demonstrate a case of anorexia nervosa in the elderly and to highlight the need for broadening of current diagnostic criteria. Clinical picture: First onset of anorexia nervosa in a 72-year-old woman following bereavement of her husband. Treatment: Nine treatments of electroconvulsive therapy. Outcome: Treatment resulted in remission of the depressive symptoms and improvement of eating behaviour. Conclusions: Anorexia nervosa does occur in the elderly and can be difficult to detect. Where comorbid depression exists it requires aggressive treatment.

Decreased Bone Density in Adolescent Girls With Anorexia Nervosa

PEDIATRICS ◽  
1990 ◽  
Vol 86 (3) ◽  
pp. 440-447 ◽  
Author(s):  
Laura K. Bachrach ◽  
David Guido ◽  
Debra Katzman ◽  
Iris F. Litt ◽  
Robert Marcus
Keyword(s):  
Bone Mineral Density ◽  
Body Mass Index ◽  
Anorexia Nervosa ◽  
Bone Density ◽  
Bone Mass ◽  
Body Mass ◽  
Bone Mineral ◽  
Whole Body ◽  
Mineral Density ◽  
Control Subjects

Osteoporosis develops in women with chronic anorexia nervosa. To determine whether bone mass is reduced in younger patients as well, bone density was studied in a group of adolescent patients with anorexia nervosa. With single- and dual-photon absorptiometry, a comparison was made of bone mineral density of midradius, lumbar spine, and whole body in 18 girls (12 to 20 years of age) with anorexia nervosa and 25 healthy control subjects of comparable age. Patients had significantly lower lumbar vertebral bone density than did control subjects (0.830 ± 0.140 vs 1.054 ± 0.139 g/cm2) and significantly lower whole body bone mass (0.700 ± 0.130 vs 0.955 ± 0.130 g/cm2). Midradius bone density was not significantly reduced. Of 18 patients, 12 had bone density greater than 2 standard deviations less than normal values for age. The diagnosis of anorexia nervosa had been made less than 1 year earlier for half of these girls. Body mass index correlated significantly with bone mass in girls who were not anorexic (P < .05, .005, and .0001 for lumbar, radius, and whole body, respectively). Bone mineral correlated significantly with body mass index in patients with anorexia nervosa as well. In addition, age at onset and duration of anorexia nervosa, but not calcium intake, activity level, or duration of amenorrhea correlated significantly with bone mineral density. It was concluded that important deficits of bone mass occur as a frequent and often early complication of anorexia nervosa in adolescence. Whole body is considerably more sensitive than midradius bone density as a measure of cortical bone loss in this illness. Low body mass index is an important predictor of this reduction in bone mass.

Childhood phenotypic manifestations of genetic risk for anorexia nervosa in the Norwegian Mother, Father and Child Cohort Study (MoBa)

2021 ◽  
Author(s):  
Ziada Ayorech ◽  
Neil Martin Davies ◽  
Hunna Watson ◽  
Zeynep Yilmaz ◽  
Martin Tesli ◽  
...  
Keyword(s):  
Mental Health ◽  
Body Mass Index ◽  
Early Childhood ◽  
Anorexia Nervosa ◽  
Cohort Study ◽  
Genetic Risk ◽  
Aggressive Behaviour ◽  
Eating Problems ◽  
Future Studies ◽  
Study Results

Anorexia nervosa (AN) polygenic liability has been associated with mental health traits, eating problems, and body mass index (BMI) in adolescence and adulthood, but little is known about its manifestations in early childhood. We explore AN polygenic score (PGS) associations with six childhood domains: BMI, eating problems, neurodevelopment, emotional problems, disruptive/aggressive behaviour, and temperament/personality in 15,205 children from the Norwegian Mother, Father and Child Cohort Study. Results did not support associations between AN PGS and developmental phenotypes in girls. For boys, we observed an association between AN PGS and higher temperamental fussiness at 6 months, (b= 0.036 [95% CI=0.010,0.061]). Our results suggest that genetic risk for AN as indexed by the PGS has few observable manifestations in key neurodevelopmental domains in the first 8 years of life. Future studies with more powerful PGS that track children longer may aid in understanding how and when genetic risk for AN manifest developmentally.

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