scholarly journals A clinical and demographic profile of the cleft lip and palate in Sub-Himalayan India: A hospital-based study

2012 ◽  
Vol 45 (01) ◽  
pp. 115-120 ◽  
Author(s):  
Jyoti Dvivedi ◽  
Sanjay Dvivedi
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Health Workers ◽  
Tertiary Care ◽  
Case Series ◽  
Care Hospital ◽  
Low Socioeconomic ◽  
The Status ◽  
Baseline Information ◽  
History Of

ABSTRACT Objectives: To study the cleft lip and cleft palate in the poverty stricken Sub-Himalayan Garhwal region of India, being a commonly seen congenital abnormality and scarcity of studies about the demography of cleft in this region. Design: A prospective cohort observational case series was performed on 4657 cleft patients at a Tertiary care Hospital in Dehradun, India, over a period of 5 years. Outcome measures: The authors investigated the differences between age and sex with cleft status and family history of clefts, birth order, religion, socioeconomic status, parent literacy, source of information for treatment, haematological investigations showing the status of infection and coagulation in such children and satisfaction after treatment. Results: Seventy-two percent parents of cleft lip patients were illiterate, and only 8% were graduates, the majority of patients were from the low socioeconomic class. The siblings of 1.1% of the cleft patients had similar deformity. Anemia was seen in 83.16% cases which was commonly microcytic hypochromic type and eosinophilia was seen in 25.50% of cases. In the coagulation profile, International Nationalized Ratio was found to be raised in 52.12%. Almost 95% of the families were fully satisfied by the treatment and results. Conclusion: This study will provide baseline information on the status of these less privileged cleft patients in this mountainous region for future reference to health workers.

Morphological Presentation of Orofacial Clefts: An Epidemiological Study of 5004 Patients in a Tertiary Care Hospital of Central India

2021 ◽  
pp. 105566562110577
Author(s):  
Jaideep Singh Chauhan ◽  
Sarwpriya Sharma
Keyword(s):  
Cleft Palate ◽  
Epidemiological Study ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tertiary Care ◽  
Central India ◽  
Care Hospital ◽  
Orofacial Clefts ◽  
Chi Square ◽  
The Right

Objective: To analyse the morphological presentation of orofacial clefts, gender, syndromes and systemic anomalies associated with them. Design: This was an epidemiological study performed in the patients who were registered for cleft lip and palate surgeries in our centre. The data was evaluated both retrospectively as well as prospectively. Patients/ Participants: The patients registered from November 2006 to April 2021 were studied. Out of 5276 patients, data of 5004 cases were analysed, rest 272 patients were excluded due to lack of information. Statistical analysis and Chi square test were applied. Results: Cleft deformities were more common in males than females. Cleft lip with palate was the commonest phenotype (52.2%). It was followed by isolated cleft lip (22.9%), isolated cleft palate (22.1%), rare clefts (1.62%) and syndromic clefts (1.18%). Unilateral variants were more frequent than bilateral. In unilateral, left side was more common than the right side. Among bilateral, most of the cases had premaxillary protrusion. In the present study, 3.46% of all the patients had associated anomalies affecting their other organs. Less common cleft phenotypes like microform cleft lip and submucous cleft palate ± bifid uvula showed frequency of 0.62% and 0.64% respectively. Conclusion: Thorough examination of cleft deformity should be done as it may appear as an isolated deformity or part of a syndrome and have associated systemic anomalies. This may help us to deliver comprehensive care to the patients and can prevent potential operative complications.

Otolaryngology Service Usage in Children With Cleft Palate

2018 ◽  
Vol 55 (5) ◽  
pp. 743-746 ◽  
Author(s):  
Kenneth R. Whittemore ◽  
Jenna M. Dargie ◽  
Briana K. Dornan ◽  
Brian Boudreau
Keyword(s):  
Cleft Palate ◽  
Cleft Lip And Palate ◽  
Tertiary Care ◽  
Case Series ◽  
Upper Airway ◽  
Care Hospital ◽  
Tympanostomy Tube ◽  
Increased Risk ◽  
Tympanostomy Tubes ◽  
Clinic Visits

Objectives: To determine the usage of otolaryngology services by children with cleft palate at a pediatric tertiary care facility. Design: Retrospective case series. Setting: Specialty clinic at a pediatric tertiary care hospital. Patients: Children born between January 1, 1999, and December 31, 2002, with the diagnosis of cleft palate or cleft lip and palate. A total of 41 female and 48 male patients were included. Main Outcome Measures: Total number of otolaryngology clinic visits and total number of otolaryngologic surgeries (tympanostomy tube placements and other otologic or upper airway procedures). Results: In the first 5 years of life, these children utilized an average of 8.2 otolaryngology clinic visits (SD = 5.0; range: 1-22) and underwent 3.3 tympanostomy tube surgeries (SD = 2.0; range: 0-10). Seventy-three had their first tube placed at the time of palate repair, and 4 at the time of lip repair. Fifty-one (57.3%) required other otologic or upper airway procedures, including tonsillectomy and/or adenoidectomy (27 children), removal of tympanostomy tubes (24 children), tympanomastoidectomy (3 children), and tympanoplasty (14 children). Of the children who underwent other procedures, they underwent a mean of 1.67 (SD = 0.84; range: 1-4) surgeries. Conclusions: Children with cleft palate are at increased risk for eustachian tube dysfunction, frequently utilize otolaryngology care, and typically receive multiple sets of tympanostomy tubes. This study found that children with cleft palate receive on average of approximately 3 sets of tympanostomy tubes, and the majority required another otologic or upper airway surgery.

Pattern of Cleft Lip and Palate in Hospital-Based Population in Saudi Arabia: Retrospective Study

2008 ◽  
Vol 45 (6) ◽  
pp. 592-596 ◽  
Author(s):  
Aziza Aljohar ◽  
Kandasamy Ravichandran ◽  
Shazia Subhani
Keyword(s):  
Saudi Arabia ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tertiary Care ◽  
Positive Family History ◽  
Care Hospital ◽  
Associated Anomalies ◽  
Cleft Lip Palate ◽  
Isolated Cleft Palate

Objective: To report the patterns of cleft lip and/or cleft palate in Saudi Arabia from data collected at a tertiary care hospital. Design and Setting: King Faisal Specialist Hospital and Research Center, Riyadh. Patients: All the cleft lip and/or cleft palate patients registered in the Cleft Lip/Palate and Craniofacial Anomalies Registry from June 1999 to December 2005. Results: Retrospectively, 807 cases of cleft lip and/or palate were registered. There were 451 boys and 356 girls. Cleft lip and palate was more common (387) than isolated cleft palate (294) and isolated cleft lip (122). Boys predominated in cleft lip and palate and cleft lip; whereas, girls predominated in isolated cleft palate, with boy to girl ratios of 1.6:1, 1.2:1, and 0.9:1 for cleft lip and/or palate, isolated cleft lip, and isolated cleft palate, respectively. The Riyadh region had more cases (32.0%) than the Asir (15.6%) and Eastern (14.6%) regions. Parents of 439 individuals had consanguineous marriages. A positive family history of cleft was seen in 224 cases. Of 238 cases with associated anomalies, 91 had congenital heart disease. Of the children with isolated cleft palate, 40.5% had associated anomalies, whereas only 23.0% of the children with isolated cleft lip or cleft lip and palate had associated malformations. Conclusion: The pattern of cleft observed in this study does not differ significantly from those reported in the literature for Arab populations.

scholarly journals Rhino Orbital Cerebral Mucormycosis in settings of Covid-19 infection: A Case Series of Thirteen Patients

2022 ◽  
Author(s):  
Rajesh Verma ◽  
Rajarshi Chakraborty ◽  
Keerthiraj DB ◽  
Kingzang Wangda ◽  
Veerendra Verma ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Public Awareness ◽  
Tertiary Care ◽  
Case Series ◽  
Care Hospital ◽  
Imaging Features ◽  
Initial State ◽  
Northern India ◽  
History Of

Abstract Background Rhino-Orbital-Cerebral Mucormycosis (ROCM) is an important infectious disease encountered in huge number in this recent post-covid 19 era. An alteration in defence immune system during covid-19 illness, in the presence of uncontrolled hyperglycaemia has led to the new epidemic of ROCM especially in developing nations like India. Method This case series of thirteen patients illustrates the various clinical presentation, laboratorical parameters, imaging features and outcome of patients of ROCM admitted in a tertiary care hospital in Northern India. Result In our case series, a total of 13 newly diagnosed cases of Rhino-Orbital-Cerebral Mucormycosis were studied. History of covid-19 illness was observed in 7 cases (53.8%), use of steroid during Covid-19 illness was seen in 5 cases (38.5%), oxygen therapy was given in 4 cases (30.8%). Co-morbid state in the form of diabetes mellitus was present in 12 cases (92.3%) with mean duration 16.69 months with an important finding of 6 cases (46.2%) having new-onset diabetes; hypertension in present in 3 cases (23.1%). Magnetic resonance imaging of paranasal sinuses showed involvement of multiple sinuses in all the 13 cases(100%), including maxillary and ethmoidal sinuses, with frontal in 12 cases (92.3%), sphenoidal in 11 cases (84.6%), symmetric in 9 cases (69.2%), mastoiditis in 4 cases (30.8%), maxillary space involvement in 4 cases (30.8%), palatal involvement in 1 case (7.7%). Multi-speciality approach treatment was given in the liposomal amphotericin B therapy in all the patients along with thorough endo-nasal debridement done in all cases, transcutaneous retrobulbar amphotericin B in 6 cases (46.2%) with exenteration done in 7 patients (53.9%). At 3 months of follow-up, there was substantial clinical improvement in all the cases. Conclusion There should be definite emphasis on high suspicion of mucor clinically for early diagnosis and aggressive management at initial state of diagnosis for better outcome. The need for sustained proper glycemic control during covid 19 era along with judicious use of steroid and public awareness for early symptoms and manifestations of mucor can curb the magnitude of such potentially opportunistic epidemic to a substantial rate. The longer the infection remains undetected, the greater the devastation ROCM can impose, of which blindness is an important hazard.

scholarly journals Determination of Risk Factors for Pre–Eclampsia in aTertiary Hospital of Bangladesh

2017 ◽  
Vol 16 (1) ◽  
pp. 29-32
Author(s):  
Sabina Yeasmin ◽  
M Jalal Uddin
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Early Stage ◽  
Past History ◽  
Tertiary Care ◽  
Care Hospital ◽  
Socioeconomic Condition ◽  
Low Socioeconomic ◽  
History Of

Background: Pre-eclampsia is an idiopathic disorder of pregnancy characterized by proteinuric hypertention and still one of the important causes of maternal and fetal mortality.The identification of its predisposing factors before and during early stage of pregnancy will help in reducing the mortality.Objective:The objective of the present study is to determine the risk factors for pre-eclampsia among pregnant women in a tertiary level hospital.Methods: This study was conducted in the Department of Obstetrics and Gynaecology of a tertiary care hospital in Chittagong, Bangladesh, from January to June 2015.A total number of 50 pregnant women with pre-eclampsia who admitted in this hospital were selected as study group.This was hospital based descriptive study.Results: Most of the partcipants were within 21-30 years of age group and mean age 24.06 ± 3.71.The factors that were found to be significant predictors of risk for development of PE were primigravida, low socioeconomic condition,family history of PE & hypertension, past history of PE and hypertention, past history of diabetes mellitus was also associated with development of PE.Chatt Maa Shi Hosp Med Coll J; Vol.16 (1); Jan 2017; Page 29-32

Sutureless Skin Closure for Cleft Lip Repair

2006 ◽  
Vol 43 (6) ◽  
pp. 656-658 ◽  
Author(s):  
V. Mourougayan
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Skin Closure ◽  
Care Hospital ◽  
Age Group ◽  
Absorbable Sutures ◽  
Cleft Lip Repair

Objective: To study the quality of scars following the use of butyl cyanoacrylate to close the skin during cleft lip repair. Design: Nonrandomized prospective study. Setting: Tertiary care hospital. Patients: Patients (n = 104) with cleft lip and palate in combination of various degrees of cleft with the age group ranging from 3 months to 5 years. Interventions: Use of butyl cyanoacrylate to close the skin during cleft lip repair after inserting dermal stitches with delayed absorbable sutures. Results: None of the 104 patients required revision of the vertical scar, which was excellent in nature. No patients had complications such as wound infection, dehiscence, nasal obstruction, or eyelid adhesion. Conclusions: Quality of the scar following the closure of skin of cleft lip repair using butyl cyanoacrylate was considered excellent.

scholarly journals Prevalence of Dental Anomalies in the Patient with Cleft Lip and Palate Visiting a Tertiary Care Hospital

2020 ◽  
Vol 58 (228) ◽  
Author(s):  
Leeza Pradhan ◽  
Pramila Shakya ◽  
Swosti Thapa ◽  
Kiran Kishor Nakarmi ◽  
Anjana Maharjan ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Lateral Incisor ◽  
Care Hospital ◽  
Dental Anomalies ◽  
Cross Sectional ◽  
Institutional Review

Introduction: Dental anomaly is one of the major problems in a child born with cleft lip and palate. These anomalies have deleterious effects on the dentition leading to aesthetic problems, impairment of mastication andimproper phonation. The aim of our study was to find out the prevalence of dental anomalies in patient with cleft lip and/or palate radiographically. Methods: A descriptive cross-sectional study was conducted from the 208 radiographs, collected by the convenience samplingtechnique with cleft lip and/or palate in Department of Burns, Plastic and Reconstructive Surgery, Nepal Cleft and Burn Centre, Kirtipur Hospital from January 2017 to July 2019.Ethical clearance for the study was obtained from Institutional Review Committee. Demographic data were collected and radiographs were evaluated for possible dental anomalies. Data obtained were entered and analysed in Statistical Package for Social Sciences version 23. Results: Dental anomalies were highly prevalent among cleft lip and palate patients with at least one anomaly present in 188 (90.4%) of patients with male 120 (57.4%) presenting more anomalies than female 88 (42.6%) population. The most common anomaly was dental agenesis 161 (77.9%). The prevalence of positional anomaly, morphological anomaly and supernumerary teeth were found to be 54 (26%), 33 (15.9%) and 20 (10%) respectively. Lateral incisor showed the highest incidence of agenesis among all other missing teeth 223 (65.2%). Conclusions: The prevalence of dental anomalies among patients with cleft lip and/or palate was found to be high. Tooth agenesis was the most common anomaly observed in the study with lateral incisor having the highest incidence of agenesis.

scholarly journals Is hormonal contraceptive risk for congenital malformation?

2019 ◽  
Vol 6 (4) ◽  
pp. 1784
Author(s):  
Prabhuswami Hiremath ◽  
R. P. Patange ◽  
J. A. Salunkhe ◽  
Vaishali R. Mohite ◽  
Prakash Naregal
Keyword(s):  
Congenital Malformation ◽  
Birth Control ◽  
Cleft Lip ◽  
Chromosomal Abnormalities ◽  
Care Center ◽  
Tertiary Care ◽  
Hormonal Contraceptives ◽  
Care Hospital ◽  
History Of ◽  
Birth Control Pills

Background: Little research is conducted in the safety of emergency contraceptives so the potential for developmental toxicity has not been evaluated.Methods: This hospital based descriptive study was conducted at tertiary care center, Krishna Hospital. Mothers who are diagnosed to have congenital birth defected fetus through antenatal examinations, delivered baby with diagnoses of congenital malformation, congenital malformed admitted neonates at Tertiary care hospital or came for reference services were assessed from September 2016 to August 2017.Results: The prevalence with number of birth, it is 1.4% and calculating with number of neonates admitted its prevalence rate is 5.3%. Overall in the hospital the prevalence noted is 0.2%. 283 mothers were diagnosed to have congenital malformation baby, among these, 264 (93.3%) mothers not had any history of birth control pills use and only 19 (6.7%) mothers stated that they used the birth control pills. Those used birth control pills in those 4 babies (1.4%) born with nervous system defects, 3 babies (1.1%) had cleft lip and cleft palate, and 2 (0.7%) babies had digestive system, musculoskeletal system and chromosomal abnormalities. Association between congenital malformation and history of Use of birth control pills shows strong association.Conclusions: The problem of conclusively proving a small increase in the incidence of rare abnormalities is very formidable. This may be due in part to the fact that the anomalies associated with hormonal contraceptives may occur primarily in those children who are predisposed genetically.

scholarly journals Frequency of maternal & perinatal mortality and maternal morbidity among obstetrical patients referred with history of unattended pregnancy.

2021 ◽  
Vol 28 (01) ◽  
pp. 80-85
Author(s):  
Amber Khawaja ◽  
Fiza Ali Khan ◽  
Asifa Abdul Jabbar ◽  
Naeem Akhter Khokhar ◽  
Saima Farook ◽  
...  
Keyword(s):  
Maternal Mortality ◽  
Perinatal Mortality ◽  
Gestational Age ◽  
Maternal Morbidity ◽  
Tertiary Care ◽  
Case Series ◽  
Antenatal Visit ◽  
Care Hospital ◽  
Case Series Study ◽  
History Of

Objective: To determine the frequency of fetomaternal morbidity and mortality among obstetric patients referred to tertiary care hospital with history of no antenatal visit. Study Design: Descriptive Case Series Study. Setting: Gambat Institute of Medical Sciences, Sindh Province. Period: June 2018 to December 2018. Material & Methods: About 175 pregnant females aged 18-35 years, having alive singleton pregnancy, gestational age >20-40 week without any history of obtaining antenatal care facility were included and followed-up till delivery and outcome were noted. Results: Mean age of females was 27.49 ± 4.46 years (18-35). Mean gestational age was 34.03 ± 4.07 weeks. About two third women (63%) were referred from rural areas. Maternal mortality rate was 12.6% while perinatal mortality was about 21.7%. Frequency of maternal morbidity of recorded as 34.9% case of hemorrhage, 36.6% case of anemia, 12.6% case of dystocia, 29.7% case of pre-eclampsia, 23.4% case of eclampsia & 19.4% case of sepsis. Maternal age was significant effect modifier for the frequency of pre-eclampsia, sepsis and maternal mortality (p<0.05). Conclusion: Maternal and perinatal morbidity & mortality are very high among women who have not attended the antenatal check-up. The major causes are haemorrhage, anaemia, pre-eclampsia/ eclampsia, dystocia and sepsis.

Prevalence of Stunting in Syrian Refugee Children With Cleft Lip and/or Cleft Palate in Time of Crisis: A Call for Intervention

2020 ◽  
Vol 57 (10) ◽  
pp. 1166-1170
Author(s):  
Bachar F. Chaya ◽  
Rawad Chalhoub ◽  
Rola Jaafar ◽  
Nour Nahhas ◽  
Ghassan Abu-Sittah
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Cleft Lip ◽  
Tertiary Care ◽  
Refugee Children ◽  
Care Hospital ◽  
Low Socioeconomic ◽  
Stunted Growth ◽  
Syrian Refugee ◽  
Medical Chart Review

Objective: Our study aims to compare the prevalence of stunted growth in Syrian refugee children with cleft lip and/or palate (CL±CP) to other children with CL±CP of similar socioeconomic status. Design: A retrospective medical chart review. Setting: Center for Cleft and Craniofacial Surgery at a tertiary care hospital in Lebanon in the period between January 2013 and May 2019. Patients, Participants: One hundred three Syrian refugee children and 70 Lebanese children <18 years of low socioeconomic status who have CL, CP, or both. Interventions: These patients underwent cleft repair surgeries at our center. Main Outcome Measure(s): Stunted growth measured by calculating the height-for-age z-score (HAZ). Results: Using a confidence interval of 95%, the prevalence of stunting is significantly higher among Syrian refugees ( P < .003). The prevalence of stunting and age of presentation were positively correlated ( P < .02). There was no difference in stunting between patients with CP and CL ( P < .746). There was no difference in stunting between genders. Conclusions: The majority of Syrian refugee patients with CL±CP fall on the malnourished side of the nutritional spectrum as reflected by the high percentage of stunting as well as a mean of −1 for the HAZ.

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