scholarly journals A blast from the past!: The value of adding single slice magnetic resonance myelography sequence to magnetic resonance imaging of the spine; a flashback to the conventional myelography of the past

2014 ◽  
Vol 5 (16) ◽  
pp. 523 ◽  
Author(s):  
PV Santosh Rai ◽  
K Santosh ◽  
Shrijeet Chakraborti ◽  
Shivananda Pai ◽  
Ishwara Keerthi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
The Past ◽  
Single Slice

Multiple Sclerosis and Cognitive Impairment

2021 ◽  
pp. 39-41
Author(s):  
Cristina Valencia-Sanchez ◽  
Jonathan L. Carter
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Information Processing ◽  
Magnetic Resonance ◽  
Processing Speed ◽  
Rehabilitation Program ◽  
Resonance Imaging ◽  
The Past ◽  
Demyelinating Lesions

A 60-year-old woman with a history of multiple sclerosis was evaluated for cognitive concerns. At age 30 years she had an episode of optic neuritis, followed by an episode of bilateral lower extremity numbness at age 35 years. In the following years, she had at least 6 further multiple sclerosis relapses, the last one approximately 3 years before the current presentation. She was initially treated with interferon, but she did not tolerate it. She had been taking glatiramer acetate for the past 3 years. She had noticed progressive deterioration of her gait for the past 3 years, having to use a cane on occasions. Magnetic resonance imaging of the brain showed multiple demyelinating lesions), and magnetic resonance imaging of the cervical spine showed 1 small demyelinating lesion at C6. Vitamin B12 level and thyroid function were normal. Comprehensive neuropsychological testing showed multidomain cognitive impairment, mainly impairment of speed of information processing, spatial discrimination skills, and attention/concentration. The patient’s multiple sclerosis phenotype was consistent with secondary progressive multiple sclerosis. Her cognitive impairment profile, mainly affecting information processing speed and disinhibition suggestive of frontal dysfunction, was consistent with multiple sclerosis. The patient began a cognitive rehabilitation program, and learning and memory aids were recommended. Lifestyle changes were also recommended, including weight loss and physical exercise. She was given recommendations for sleep hygiene and began taking gabapentin for neuropathic pain and restless legs. Cognitive impairment is common in patients with multiple sclerosis. Slowed cognitive processing speed and episodic memory decline are the most common cognitive deficits in MS, with additional difficulties in executive function, verbal fluency, and visuospatial analysis.

scholarly journals Iron Oxide Nanoparticles: An Alternative for Positive Contrast in Magnetic Resonance Imaging

Inorganics ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 28 ◽  
Author(s):  
Irene Fernández-Barahona ◽  
María Muñoz-Hernando ◽  
Jesus Ruiz-Cabello ◽  
Fernando Herranz ◽  
Juan Pellico
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Positive Contrast ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
The Past ◽  
T1 Contrast

Iron oxide nanoparticles have been extensively utilised as negative (T2) contrast agents in magnetic resonance imaging. In the past few years, researchers have also exploited their application as positive (T1) contrast agents to overcome the limitation of traditional Gd3+ contrast agents. To provide T1 contrast, these particles must present certain physicochemical properties with control over the size, morphology and surface of the particles. In this review, we summarise the reported T1 iron oxide nanoparticles and critically revise their properties, synthetic protocols and application, not only in MRI but also in multimodal imaging. In addition, we briefly summarise the most important nanoparticulate Gd and Mn agents to evaluate whether T1 iron oxide nanoparticles can reach Gd/Mn contrast capabilities.

Neurogenic Stuttering: Further Corroboration of Site of Lesion

1996 ◽  
Vol 75 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Reinhardt J. Heuer ◽  
Robert Thayer Sataloff ◽  
Steven Mandel ◽  
Nancy Travers
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Past Century ◽  
Unilateral Lesion ◽  
Resonance Imaging ◽  
The Past ◽  
Magnetic Resonance Imaging Mri

Cases of neurogenic stuttering have been reported in the literature throughout the past century. Site(s) of lesion(s) have been documented usually by association of symptoms, EEG studies and occasionally by computed tomography (CT). The authors present three cases in which the site(s) of lesion(s) are documented by CT, magnetic resonance imaging (MRI) and SPECT. This study supports previous findings of neurogenic stuttering following either bilateral diffuse lesions or a unilateral lesion. In at least one case, the actual site of the lesion would have been missed without the use of SPECT testing. EEG studies were not helpful in identifying the site of the lesion.

Enhanced magnetic resonance imaging in multiple sclerosis

2000 ◽  
Vol 6 (5) ◽  
pp. 320-326 ◽  
Author(s):  
M Filippi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Tissue Loss ◽  
Resonance Imaging ◽  
The Past ◽  
Magnetic Resonance Imaging Mri ◽  
The One ◽  
The Relationship

Gadolinium-enhanced magnetic resonance imaging (MRI) is very sensitive in the detection of active lesions of multiple sclerosis (MS) and has become a valuable tool to monitor the evolution of the disease either natural or modified by treatment. In the past few years, several studies, on the one hand, have assessed several ways to increase the sensitivity of enhanced MRI to disease activity and, on the other, have investigated in vivo the nature and evolution of enhancing lesions using different non-conventional MR techniques to better define the relationship between enhancement and tissue loss in MS. The present review is a summary of these studies whose results are discussed in the context of MS clinical trial planning and monitoring.

Intralabyrinthine Schwannomas

1994 ◽  
Vol 110 (6) ◽  
pp. 517-523 ◽  
Author(s):  
Karen Jo Doyle ◽  
Derald E. Brackmann
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Incidental Findings ◽  
Clinical Presentation ◽  
Semicircular Canals ◽  
Resonance Imaging ◽  
The Past

Intraiabyrinthine schwannomas are unusual tumors of the vestibule, cochiea, semicircular canals, or some combination of these three, which in the past have been reported as incidental findings at autopsy or surgery. We summarize eight cases of intralabyrinthine schwannomas diagnosed by magnetic resonance Imaging at the House Ear Clinic during the past 3 years. We discuss the typical clinical presentation and treatment of cochlear vs. vestibular intralabyrinthine schwannomas.

Identification of Disappearing Brain Lesions With Intraoperative Magnetic Resonance Imaging Prevents Surgery

Neurosurgery ◽  
2010 ◽  
Vol 67 (4) ◽  
pp. 1061-1065 ◽  
Author(s):  
Christina S Sutherland ◽  
John JP Kelly ◽  
William Morrish ◽  
Garnette R Sutherland
Keyword(s):  
Magnetic Resonance Imaging ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Brain Lesions ◽  
Resonance Imaging ◽  
Intraoperative Magnetic Resonance Imaging ◽  
The Past ◽  
University Of Calgary ◽  
The University

Abstract BACKGROUND: Typically, neurosurgery is performed several weeks after diagnostic imaging. In the majority of cases, histopathology confirms the diagnosis of neoplasia. In a small number of cases, a different diagnosis is established or histopathology is nondiagnostic. The frequency with which these outcomes occur has not been established. OBJECTIVE: To determine the frequency and outcome of disappearing brain lesions within a group of patients undergoing surgery for suspected brain tumor. METHODS: Over the past decade, 982 patients were managed in the intraoperative magnetic resonance imaging unit at the University of Calgary, Calgary, Alberta, Canada. These patients have been prospectively evaluated. RESULTS: In 652 patients, a brain tumor was suspected. In 6 of the 652 patients, histopathology indicated a nontumor diagnosis. In 5 patients, intraoperative images, acquired after induction of anesthesia, showed complete or nearly complete resolution of the suspected tumor identified on diagnostic magnetic resonance imaging acquired 6 ± 4 (mean ± SD) weeks previously. Anesthesia was reversed, and the surgical procedure aborted. The lesions have not progressed with 6 ± 2 years of follow-up. CONCLUSION: Intraoperative magnetic resonance imaging prevented surgery on 5 patients with disappearing lesions.

Magnetic Resonance Imaging Contrast Agents and the Nuclear Pharmacist

1989 ◽  
Vol 2 (3) ◽  
pp. 191-195
Author(s):  
Jeffrey A. Clanton
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Resonance Imaging ◽  
Specific Group ◽  
The Past ◽  
Iodinated Contrast ◽  
Magnetic Resonance Imaging Contrast ◽  
Magnetic Resonance Imaging Mri ◽  
Insight Into

The nuclear pharmacist works with a very specific group of drugs. These drugs generally exhibit no toxic effects and are used almost exclusively for diagnosis. In the past these have been the radioactive drugs used in nuclear medicine and the iodinated contrast agents used in radiology. However, with the advent of magnetic resonance imaging (MRI), there is an additional class of drugs used in radiology, the magnetopharmaceuticals. These drugs are designed especially for increasing diagnostic sensitivity with MRI. This article is intended to provide topical insight into the basics of MRI and magnetopharmaceuticals.

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