scholarly journals Unresected pediatric myoepithelial carcinomas treated with alternating chemotherapy cycles with adjuvant radiotherapy

2015 ◽  
Vol 01 (02) ◽  
pp. 109-111
Author(s):  
Michael Dorbad ◽  
Peter Lim ◽  
Jeffrey Taylor

ABSTRACTMyoepithelial carcinomas of soft tissue origin are rare tumors in the pediatric population. Due to the rarity of this malignancy, very few cases have been reported in the literature, and a consensus on treatment has not been established. Most myoepithelial carcinomas of soft tissue present in the extremities and are treated with surgical excision followed by adjuvant radiotherapy. We report 2 cases of pediatric myoepithelial carcinoma presenting with vertebral involvement making complete surgical removal impossible. These patients underwent chemotherapy and adjuvant radiotherapy as the main treatment for their primary tumors.

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Samuel H. Cho ◽  
Timothy Fritz ◽  
Lynn J. Cronin ◽  
Stephen D. Cohle

Cardiac fibromas are benign primary tumors composed of connective tissue and fibroblasts. These uncommon tumors are primarily found in the pediatric population, and their prevalence among the adult population is exceedingly rare. We report a case of an adult with nonspecific symptoms, who was subsequently found to have a solitary mass located in the left ventricle. This case highlights an unusual finding in an adult who through various imaging modalities, surgical excision, and immunohistological analysis was found to have a cardiac fibroma.


Author(s):  
Megha Narayan ◽  
Rajat Kumar Singh ◽  
Aparna Singh ◽  
Siddharth Anand ◽  
Sulekha Sulekha

AbstractTraumatic injuries to maxillary anterior teeth while playing are common in children and adolescents. Sequelae of such trauma include broken, lost, aspirated, and swallowed tooth. At times, the broken tooth fragments get embedded in the adjoining soft tissue and frequently get neglected during diagnosis. The present case report discusses the case of a 13-year-old adolescent who had broken tooth fragment emerged in the lower lip and its surgical excision to prevent detrimental reactions and scarring.


Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 67
Author(s):  
Mario F. Scaglioni ◽  
Matteo Meroni ◽  
Elmar Fritsche ◽  
Bruno Fuchs

Background and Objectives: The definitive treatment of soft tissue sarcomas (STS) requires a radical surgical removal of the tumor, which often leads to large soft tissue defects. When they are located in the limbs, significant damage to the lymphatic pathways is not uncommon. In the present article, we present different techniques aimed at both reconstructing the defect and restoring sufficient lymph drainage, thus preventing short- and long-term lymphatic complications. Materials and Methods: Between 2018 and 2020, 10 patients presenting a soft tissue defect with lymphatic impairment received a locoregional reconstruction by means of either pedicled or free SCIP flap. Seven patients required a second flap to reach a good dead space obliteration. In six cases, we performed an interpositional flap, namely a soft tissue transfer with lymphatic tissue preservation, and in four cases a lymphatic flow-through flap. In all cases, the cause of the defect was STS surgical excision. The average age was 60.5 years old (ranging 39–84), seven patients were females and six were males. Results: All the patients were successfully treated. In two cases, minor post-operative complications were encountered (infected seroma), which were conservatively managed. No secondary procedures were required. The average follow-up was 8.9 months (ranging 7–12 months). No signs of lymphedema were reported during this time. In all cases, complete range of motion (ROM) and a good cosmetic result were achieved. Conclusions: A reconstructive procedure that aims not only to restore the missing volume, but also the lymphatic drainage might successfully reduce the rate of postoperative complications. Both lymphatic interpositional flaps and lymphatic flow-through flaps could be effective, and the right choice must be done according to each patient’s needs.


2008 ◽  
Vol 9 (3) ◽  
pp. 135-141 ◽  
Author(s):  
Miguel Jaimes ◽  
Jose Muñante ◽  
Jaime Giuseppe Rodrizuez-Chessa ◽  
Sergio Olate ◽  
Jose Ricardo de Albergaria-Barbosa ◽  
...  

Abstract Aim The purpose of this report is to present a case of surgical and prosthetic treatment of a woman with inflammatory fibrous hyperplasia (IFH) and her evaluation during a six month period. Background IFH is a benign pathology, prevalent in female patients, and principally associated with ill-fitting prosthetic devices in need of adjustment. It is common for patients to require surgical removal of the hyperplastic tissue and fabrication of a new prosthesis. Case Report A 55-year-old female with a history of smoking presented with a chief complaint of missing the scheduled adjustment of her maxillary complete denture and the presence of moveable tissue under the denture. Surgical excision of the hyperplastic tissue followed with fixation of the prosthesis for six months to guide the healing of the soft tissue and to reshape the contours of the maxillary supporting tissues. Summary Surgical removal of hyperplasic soft tissue is a routine procedure, and the fixation of the prosthesis for the support of tissue during healing improves intraoral conditions for the fabrication of a new prosthesis in the future. Citation Jaimes M, Muñante J, Rodriguez-Chessa JG, Olate S, de Albergaria-Barbosa JR, Mazzonetto R, Klüppel LE. Inflammatory Fibrous Hyperplasia Treated with a Modified Vestibuloplasty: A Case Report. J Contemp Dent Pract 2008 March; (9)3:135-141.


2019 ◽  
pp. 30-34
Author(s):  
Asish Kumar Barui ◽  
Abhisek Chowdhury ◽  
T. K. Giri ◽  
S Mukharjee

Brief Background Fabrication of any dental prosthesis over a compromised residual alveolar ridge is really a challenge for prosthodontists. Fibrous or flabby ridge and highly resorbed residual alveolar ridge are two clinical situations that require special considerations during construction of any prosthesis. Mobile soft tissue and flattened alveolar ridge significantly compromise denture stability and support. There are different treatment modalities to manage these clinical conditions like surgical excision of soft tissue, ridge augmentation, modification in impression technique, etc. Materials and Methods This case report is about an old completely edentulous male patient who reported with a complaint of difficulty in chewing with his present denture. Discussion Prosthodontic management of a patient with compromised residual alveolar ridges needs special consideration . Selection of treatment modality depends on patients general health ,clinical condition of residual alveolar ridges , financial capacity and skill of the clinician A modification from conventional impression procedure was used to record maxillary flabby anterior ridge and neutral zone concept was applied for teeth arrangement to improve denture stability in atrophied lower alveolar ridge. Summary and Conclusions Surgical removal of soft tissue and implant supported prosthesis may not be possible in all situations. In that case a conservative approach using modified impression technique, neutral zone concept provides the basic triad of a successful denture prosthesis that is retention, stability and support. Key Words Flabby tissue, Window technique, Resorbed ridge, Neutral zone.


2020 ◽  
Vol 63 (6) ◽  
Author(s):  
Camilla de Laurentis ◽  
Julius Höhne ◽  
Claudio Cavallo ◽  
Francesco Restelli ◽  
Jacopo Falco ◽  
...  

Author(s):  
Filippo Boriani ◽  
Edoardo Raposio ◽  
Costantino Errani

: Musculoskeletal tumors of the hand are a rare entity and are divided into skeletal and soft tissue tumors. Either category comprises benign and malignant or even intermediate tumors. Basic radiology allows an optimal resolution of bone and related soft tissue areas, ultrasound and more sophisticated radiologic tools such as scintigraphy, CT and MRI allow a more accurate evaluation of tumor extent. Enchondroma is the most common benign tumor affecting bone, whereas chondrosarcoma is the most commonly represented malignant neoplasm localized to hand bones. In the soft tissues ganglions are the most common benign tumors and epithelioid sarcoma is the most frequently represented malignant tumor targeting hand soft tissues. The knowledge regarding diagnostic and therapeutic management of these tumors is often deriving from small case series, retrospective studies or even case reports. Evidences from prospective studies or controlled trials are limited and for this lack of clear and supported evidences data from the medical literature on the topic are controversial, in terms of demographics, clinical presentation, diagnosis prognosis and therapy.The correct recognition of the specific subtype and extension of the tumor through first line and second line radiology is essential for the surgeon, in order to effectively direct the therapeutic decisions.


2021 ◽  
Vol 11 (13) ◽  
pp. 5819
Author(s):  
Gianluca Botticelli ◽  
Marco Severino ◽  
Gianmaria Fabrizio Ferrazzano ◽  
Pedro Vittorini Velasquez ◽  
Carlo Franceschini ◽  
...  

Oral mucocele is a benign cystic exophytic lesion affecting the minor salivary gland and is especially present in pediatric patients (3% under 14 years). It is characterized by an extravasation or retention of fluid or mucus in the submucosal tissue of the minor salivary glands. Several surgical techniques have been proposed over the years, including the excision of the mucocele by using the injection of a hydrocolloid impression material in the light of the cyst to prevent the collapse of the cystic wall and solidify the lesion, resulting in a better cleavage plan. The combined clinical approach between the combination of Shira’s technique and the surgical excision of the cystic lesion results in a conservative surgical removal of the lesion. Here, we reported the removal of a labial mucocele in a 14-year-old male patient, using the injection of a hydrocolloid impression material. At a 12 months follow up, the patient showed complete healing of the surgical site, showing a pinkish lip lining mucosa without scarring or recurrence of the primary lesion. The combined therapeutic approach between Shira’s technique and surgical excision allows a safe and predictable excision of the labial mucocele, minimizing the risk of recurrence.


Author(s):  
Flávia Sprenger ◽  
Sofia Tokars Kluppel ◽  
Valmir Vicente Filho ◽  
Ana Carolina Staats ◽  
Raul Alberto Anselmi Junior ◽  
...  

Abstract Background The term fibromatosis refers to a spectrum of soft tissue tumors resulting from the unbridled proliferation of fibroblasts, with high infiltrative power. It is a rare neoplasm, with an incidence of about 3 cases per million. Most common sites include the abdominal wall and cavity, chest wall, scapular area, and the limbs, rarely affecting the axilla. Imaging plays a major role in surgical planning and clinical follow-up. Differential diagnosis with other soft tissue tumors may be arduous, but a correct evaluation is fundamental. Case presentation A 33-year-old case is reported for the evaluation of a palpable hardened and immobile left axillary nodule. The ultrasound reveals a solid, elongated, heterogeneous, poorly delimited, infiltrative lesion observed in the left axillary hollow, with no detectable flow in the color Doppler mode. At magnetic resonance imaging, the same elongated and expansive lesion was better defined, revealing its irregular contours, alternating areas of hypo- and hyperintense on T2, heterogeneous enhancement, and no signs of signal decay on in- and out-of-phase sequences. Due to its growth and local invasion potential, surgical excision was performed. The microscopic analysis showed long and uniform spindle cell fascicles, with clear cytoplasm and wavy nuclei, arranged in different directions, included in collagen stroma. Immunohistochemistry was positive for nuclear beta-catenin, confirming the diagnosis of fibromatosis. Conclusion Imaging methods reflect the heterogeneous nature of the lesion. This study demonstrates the importance of using a multidisciplinary approach in addition to imaging tests and histopathological study for better diagnosis and therapeutic planning. The high infiltrative power always must be reminded of, since it affects young patients and diagnosis delay can lead to mutilating surgeries.


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