scholarly journals Nanocrystalline silver gel versus conventional silver sulfadiazine cream as topical dressing for second-degree burn wound: A clinicopathological comparison

2018 ◽  
Vol 26 (1) ◽  
pp. 29 ◽  
Author(s):  
Gouranga Dutta ◽  
Nandini Das ◽  
Abhishek Adhya ◽  
Kinkar Munian ◽  
BijayKumar Majumdar
Keyword(s):  
Silver Sulfadiazine ◽  
Burn Wound ◽  
Degree Burn ◽  
Second Degree

scholarly journals A comparative study of the efficacy of nanocrystalline silver gel and silver sulfadiazine cream on the healing of second degree burn wound

2020 ◽  
Vol 7 (12) ◽  
pp. 4076
Author(s):  
Bikash Maiti ◽  
Sabyasachi Bakshi
Keyword(s):  
Healing Time ◽  
Silver Sulfadiazine ◽  
Tissue Type ◽  
Necrotic Tissue ◽  
Burn Wound ◽  
Chi Square ◽  
After Effects ◽  
Nano Crystalline ◽  
Degree Burn ◽  
Second Degree

Background: The final aim of burn management is to prevent infection, to promote early epithelialization as well as healing of wound and betterment of functional and asthetic after effects. The present study aimed to compare the effect of nano crystalline silver gel and silver sulfadiazine cream on the healing of second-degree burn wounds.Methods: After matching the inclusion and exclusion criteriaburn wounds of patients were divided into two parts (sides); one part was dressed with silver sulfadiazine cream and the other one was dressed with nano crystalline silver gel. The wound dressing was changed everyday after washing the wound with normal saline. Wound parameters were measured on the ninth day and twenth day of dressing, using clinical assessment and photographic tool. The obtained data were statistically analyzed using the Chi-square test.Results: In our study, most patients were noted to have increased epithelization, increased granulation tissue, decreased inflammation, decreased wound infection as well as decreased slough following dressing with both nanocrystalline silver gel and silver sulfadiazine cream but there were more in numbers of patients dressing with nanocrystalline silver gel.Conclusions: The effect of nanocrystalline silver gel on the reduction of the healing time and necrotic tissue amount and increasing the granulation, epithelialization, and necrotic tissue type was greater. Considering the above findings nanocrystalline silver gel is more recommended to be used for burn wounds.

673 Effect of Subcutaneous Topical Ozone Therapy on Second Degree Burn Wounds in Rats: An Experimental Study

2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S193-S193
Author(s):  
Emre Karakaya ◽  
Aydincan Akdur ◽  
H Ebru ◽  
Ayvazoglu Soy ◽  
Alev Ok Atilgan ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Silver Sulfadiazine ◽  
Male Rats ◽  
Control Group ◽  
Ozone Therapy ◽  
Burn Wounds ◽  
Degree Burn ◽  
Significant Difference ◽  
Second Degree

Abstract Introduction Burn is one of the most severe traumas that causes coagulative destruction of the skin. The use of various products that accelerate wound healing in patients with burn may affect the patient’s survival and reduce the complications that may be seen. In the present study we aimed effects of subcutaneous ozone injection on second degree burn wound. Methods A total of 72 Sprague-Dawley male rats included in the study were divided randomly into three groups (control group (CG), silver sulfadiazine group (SG), ozone group (OG)) and each group was divided randomly two subgroups (as sacrificed on d7 and on d14).A deep second degree scald burns were created on the lower back. In CG subcutaneous 0.9% serum saline was injected daily into the burn area. In SG, burns were dressed with silver sulfadiazine daily and in OG subcutaneous ozone was injected daily into the burn area. Tissue hydroxyproline level measurement and histopathological evaluation were done. Results When the groups were compared in terms of weight change, no significant difference was found on the 7th and 14th days. In the evaluation made in terms of tissue hydroxyproline, tissue hydroxyproline level in OG was found to be significantly higher on both the 7th and 14th days (p < 0.001). In histopathological evaluations, it was determined that wound healing in OG was significantly higher than in the other groups. Conclusions According to the results, subcutaneous ozone therapy is more effective than silver sulphadiazine in the healing process of second-degree burn wounds and it can be safely used in the treatment of burn wounds.

Wound Healing Activity of Avocado Peel Ointment against Second Degree Burn Wound

2021 ◽  
Author(s):  
Ma I Yang ◽  
Ermi Girsang ◽  
Ali Napiah Nasution ◽  
Chrismis Novalinda Ginting
Keyword(s):  
Wound Healing ◽  
Burn Wound ◽  
Degree Burn ◽  
Wound Healing Activity ◽  
Second Degree

Regenerated silk fibroin-based dressing modified with carnosine-bentonite nanosheets accelerates healing of second-degree burn wound

2020 ◽  
Vol 74 (10) ◽  
pp. 3243-3257
Author(s):  
Pegah Azimzadeh Asiabi ◽  
Ali Ramazani ◽  
Mehdi Khoobi ◽  
Mohsen Amin ◽  
Marzieh Shakoori ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Burn Wound ◽  
Degree Burn ◽  
Regenerated Silk Fibroin ◽  
Second Degree

scholarly journals ALOE VERA VS. SILVER SULFADIAZINE FOR TREATING SECOND-DEGREE BURN WOUNDS: EVIDENCE-BASED CASE REPORT

2019 ◽  
pp. 146-148
Author(s):  
CLARA MENNA ◽  
NABILLA CALISTA ◽  
LEORCA AURINO ◽  
ADISTI DWIJAYANTI
Keyword(s):  
Clinical Trials ◽  
Risk Reduction ◽  
Randomized Clinical Trials ◽  
Aloe Vera ◽  
Silver Sulfadiazine ◽  
Number Needed To Treat ◽  
Burn Wounds ◽  
The Third ◽  
Degree Burn ◽  
Second Degree

Objective: Current treatment for second-degree burn wounds, including silver sulfadiazine (SSD) application, may cause side effects such as delayed and incomplete wound healing, leaving a scar. Traditional plants empirically used for burn wounds, such as Aloe vera, seem to be a promising option with good safety profiles. Methods: We therefore compared Aloe vera to SSD for second-degree burn wounds based on a review of clinical trials obtained by an organized search through the Cochrane, PubMed, and DynaMed databases. Three randomized clinical trials studies were selected, two of which were critically appraised. The third study, with a different outcome assessment, was analyzed separately. Results: Two studies showed that Aloe vera was more effective in treating second-degree burn wounds than SSD 1% with an absolute risk reduction of 0.2, relative risk reduction of 0.83–1.0, and number needed to treat five patients. The Aloe vera group showed faster healing, earlier epithelialization, and earlier pain alleviation. The third study combined Aloe vera with other herbs, which showed better healing ability and restored skin hydration than those with SSD. Conclusion: Each of the three articles stated that Aloe vera was more effective than SSD for treating second-degree burn wounds. Nevertheless, each of the studies lacked methodology and comprehensive data reporting.

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