Clinical features, demography, and predictors of outcomes of SARS-CoV-2 infection at a tertiary care hospital in India: A cohort study

Objective: To find out characteristics and clinical features of children presenting with acute myocarditis at a tertiary care hospital. Study Design: Observational Study. Setting: Department of Pediatrics, Sughra Shafi Medical Complex, Sahara Medical College, Narowal, Pakistan. Period: February 2020 to February 2021. Material & Methods: A total of 71 children aged 1 month to 15 years admitted with acute myocarditis were enrolled. Acute myocarditis was labeled as short history of illness in otherwise healthy child, echocardiography evident of left ventricular dysfunctioning, cardiac biomarkers showing cardiac damage as well as electrocardiography showing acute myocarditis. Age was represented as mean and standard deviation whereas qualitative variables like gender, area of residence and clinical features were shown as frequency and percentages. Results: Out of a total of 71 children, there were 38 (53.5%) were male. Median age was recorded to be 16.6 months. Majority of the cases, 42 (59.2%) belonged to rural areas of residence. Tachycardia was the commonest clinical feature noted in 65 (91.5%) children, irritability was seen in 50 (70.4%), tachypnea in 48 (67.6%) while poor feeding was noted 44 (62.0%) children. Hepatomegaly was noted in 39 (54.9%) children. Hypotension was recorded in 35 (49.3%) children. Conclusion: Male predominance was seen among children presenting with acute myocarditis. Tachycardia, irritability, tachypnea and poor feeding were the commonest clinical features observed.

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Clinico-microbiological profile and outcomes of nosocomial sepsis in an Indian tertiary care hospital – a prospective cohort study

Pathogens and Global Health ◽

10.1179/2047773215y.0000000026 ◽

2015 ◽

Vol 109 (5) ◽

pp. 228-235 ◽

Cited By ~ 5

Author(s):

Kavitha Saravu ◽

Madhura Prasad ◽

Vandana Kalwaje Eshwara ◽

Chiranjay Mukhopadhyay

Keyword(s):

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Microbiological Profile ◽

Nosocomial Sepsis

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Factors Associated to Prevalence and Incidence of Carbapenem-Resistant Enterobacteriaceae Fecal Carriage: A Cohort Study in a Mexican Tertiary Care Hospital

PLoS ONE ◽

10.1371/journal.pone.0139883 ◽

2015 ◽

Vol 10 (10) ◽

pp. e0139883 ◽

Cited By ~ 36

Author(s):

Pedro Torres-Gonzalez ◽

Miguel Enrique Cervera-Hernandez ◽

María Dolores Niembro-Ortega ◽

Francisco Leal-Vega ◽

Luis Pablo Cruz-Hervert ◽

...

Keyword(s):

Cohort Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Factors Associated ◽

Carbapenem Resistant ◽

Fecal Carriage ◽

Carbapenem Resistant Enterobacteriaceae

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Clinical Features, Outcomes, and Risk Factors of Bloodstream Infections due to Stenotrophomonas maltophilia in a Tertiary-Care Hospital of China: A Retrospective Analysis

BioMed Research International ◽

10.1155/2019/4931501 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7

Author(s):

Yibing Chen ◽

Jijiang Suo ◽

Mingmei Du ◽

Liangan Chen ◽

Yunxi Liu ◽

...

Keyword(s):

Risk Factors ◽

Septic Shock ◽

Drug Resistance ◽

Clinical Features ◽

Stenotrophomonas Maltophilia ◽

Pathogenic Bacteria ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

T Tube

Background. Stenotrophomonas maltophilia bacteremia (SMB) is the most perilous situation as compared to other types of S. maltophilia infection. The present study aimed to investigate the clinical features, distribution, drug resistance, and predictors of survival of SMB in a tertiary-care hospital of China. Methods. SMB that occurred in a tertiary-care hospital in Beijing, China, within 9 years (2010–2018) was investigated in a retrospective study. Demographics, incidence, commodities, drug resistance, mortality, as well as antibiotics administration were summarized according to the electronic medical records. The risk factors for survival were analyzed by Chi-square test, Kaplan–Meier curve and Cox regression. Results. A total of 76 episodes of SMB were analyzed. The overall incidence of SMB fluctuated from 3.4 to 15.4 episodes per 1000 admissions over 9 years. Malignancy was the most common comorbidity. High in vitro sensitivity was observed to minocycline (96.1%), levofloxacin (81.6%), and trimethoprim-sulfamethoxazole (89.5%). Central venous catheter (CVC) (p=0.004), mechanical ventilation (MV) (p=0.006), hemodialysis (p=0.024), and septic shock (p=0.016) were significantly different between survival and death group. The 30-day mortality was 34.2% within 30 days after confirmation of blood culture. Factors such as hemodialysis (OR 0.287, 95% CI: 0.084–0.977, p=0.046), T-tube (OR 0.160, 95% CI: 0.029–0.881, p=0.035), and septic shock (OR 0.234, 95% CI: 0.076–0.719, p=0.011) were associated with survival. Conclusions. S. maltophilia is the major nosocomial blood stream infectious pathogenic bacteria. Trimethoprim-sulfamethoxazole and minocycline are optimal antibiotics for the treatment of SMB. T-tube, hemodialysis, and septic shock were the risk factors associated with survival of SMB patients.

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Evolution of trauma management at a tertiary care hospital: A cohort study

International Journal of Surgery ◽

10.1016/j.ijsu.2010.09.009 ◽

2011 ◽

Vol 9 (1) ◽

pp. 75-78 ◽

Cited By ~ 6

Author(s):

Shahryar Noordin ◽

Salim Allana ◽

Tashfeen Ahmad ◽

Ata-ul-Aleem Bhatti ◽

Hasnain Zafar ◽

...

Keyword(s):

Cohort Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Trauma Management

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Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases ◽

10.1016/j.jctube.2020.100175 ◽

2020 ◽

Vol 20 ◽

pp. 100175

Author(s):

J.A. Tornheim ◽

E. Intini ◽

A. Gupta ◽

Z.F. Udwadia

Keyword(s):

Clinical Features ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Multidrug Resistant ◽

Care Hospital ◽

Tuberculosis Patients ◽

Linezolid Resistance ◽

Resistant Tuberculosis ◽

Multidrug Resistant Tuberculosis

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Single assessment of delirium severity during postacute intensive care of chronically critically ill patients and its associated factors: post hoc analysis of a prospective cohort study in Germany

BMJ Open ◽

10.1136/bmjopen-2019-035733 ◽

2020 ◽

Vol 10 (10) ◽

pp. e035733

Author(s):

Gloria-Beatrice Wintermann ◽

Kerstin Weidner ◽

Bernhard Strauss ◽

Jenny Rosendahl

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Intensive Care ◽

Critical Illness ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Chronically Critically Ill ◽

Post Hoc

ObjectivesTo assess the delirium severity (DS), its risk factors and association with adverse patient outcomes in chronically critically ill (CCI) patients.DesignA prospective cohort study.SettingA tertiary care hospital with postacute intensive care units (ICUs) in Germany.ParticipantsN=267 CCI patients with critical illness polyneuropathy and/or critical illness myopathy, aged 18–75 years, who had undergone elective tracheotomy for weaning failure.InterventionsNone.MeasuresPrimary outcomes: DS was assessed using the Confusion Assessment Method for the Intensive Care Unit-7 delirium severity score, within 4 weeks (t1) after the transfer to a tertiary care hospital. In post hoc analyses, univariate linear regressions were employed, examining the relationship of DS with clinical, sociodemographic and psychological variables. Secondary outcomes: additionally, correlations of DS with fatigue (using the Multidimensional Fatigue Inventory-20), quality of life (using the Euro-Quality of Life) and institutionalisation/mortality at 3 (t2) and 6 (t3) months follow-up were computed.ResultsOf the N=267 patients analysed, 9.4% showed severe or most severe delirium symptoms. 4.1% had a full-syndromal delirium. DS was significantly associated with the severity of illness (p=0.016, 95% CI −0.1 to −0.3), number of medical comorbidities (p<0.001, 95% CI .1 to .3) and sepsis (p<0.001, 95% CI .3 to 1.0). Patients with a higher DS at postacute ICU (t1), showed a higher mental fatigue at t2 (p=0.008, 95% CI .13 to .37) and an increased risk for institutionalisation/mortality (p=0.043, 95% CI 1.1 to 28.9/p=0.015, 95% CI 1.5 to 43.2).ConclusionsIllness severity is positively associated with DS during postacute care in CCI patients. An adequate management of delirium is essential in order to mitigate functional and cognitive long-term sequelae following ICU.Trial registration numberDRKS00003386.

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