scholarly journals The effect of curcumin ointment on the quality of life of older adults with knee osteoarthritis: A randomized placebo clinical trial

2021 ◽  
Vol 10 (2) ◽  
pp. 79
Author(s):  
Mohsen Adib-Hajbaghery ◽  
Neda Jamali ◽  
Alireza Soleimani
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Clinical Trial ◽  
Knee Osteoarthritis

Customized Foot Insoles Have a Positive Effect on Pain, Function, and Quality of Life in Patients with Medial Knee Osteoarthritis

2013 ◽  
Vol 103 (1) ◽  
pp. 50-55 ◽  
Author(s):  
Søren Thorgaard Skou ◽  
Lea Hojgaard ◽  
Ole H. Simonsen
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Older Adults ◽  
Knee Osteoarthritis ◽  
Visual Analog Scale ◽  
Oxford Knee Score ◽  
Analog Scale ◽  
Custom Made ◽  
Arch Support

Background: Knee osteoarthritis (KOA) is a prevalent degenerative disease in older adults. Treatment strategies, including insoles, focus on reducing pain and physical disability. In medial KOA, insoles have been studied extensively with conflicting results, possibly due to heterogeneity in outcome measures and the intervention. We sought to investigate the effect of custom-made laterally wedged insoles on pain, function, and quality of life in patients with medial KOA. Methods: Fifty-one consecutive patients with medial KOA were prescribed custom-made insoles with arch support and a 5.0° to 8.7° lateral wedge. At follow-up, 42 of the 51 participants (22 men; mean age, 63 years; mean Kellgren-Lawrence, 3.4) participated. Retrospectively, participants were asked to rate the pain intensity in their affected knee before and after the intervention measured on a visual analog scale after 30 min of physical activity (primary outcome), at rest, at night, and after 50 m of walking. Additionally, they completed the Oxford Knee Score and the EQ-5D. The paired-samples t test was applied in the statistics. Results: The visual analog scale score after 30 min of physical activity was significantly reduced after the intervention (mean, 3.3 cm; 95% confidence interval, 2.1–4.5 cm; P < .001). The same significant changes were found in all of the secondary outcomes. Conclusions: There was a significant reduction in pain and improvements in function and quality of life with custom-made laterally wedged insoles with arch support in older adults with mild-to-severe medial KOA. The customization of laterally wedged insoles may be essential for the effect in medial KOA. (J Am Podiatr Med Assoc 103(1): 50–55, 2013)

scholarly journals Effects of exergames and resistance training on well-being in older adults: a randomized clinical trial

2020 ◽  
Vol 14 (3) ◽  
pp. 152-159
Author(s):  
Vandrize Meneghini ◽  
Eduardo Hauser ◽  
Camilo Luis Monteiro Lourenço ◽  
Aline Rodrigues Barbosa
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Clinical Trial ◽  
Resistance Training ◽  
Randomized Clinical Trial ◽  
General Health ◽  
Training Group ◽  
Life Assessment ◽  
Symptoms Of Depression

OBJECTIVE: To analyze the effects of an exergame-based training compared to resistance training on the quality of life and symptoms of depression in older adults. METHODS: This was a two-arm, non-blinded, randomized clinical trial. Thirty-five participants (62.09 ± 7.11 years) were randomized either on the Exergame-based Training Group (n = 17) or the Resistance Training Group (n = 18). Sessions lasted 50 to 60 minutes, three times per week, for 13 weeks. For the Exergame-based Training Group, we used games that simulate sports and adventure activities through Xbox360 Kinect™. The Resistance Training Group performed ten exercises per session for upper and lower limbs using free weights and machines, following linear periodization and individualized loads. Quality of life and symptoms of depression were assessed using the World Health Organization Quality of Life assessment - an abbreviated version (WHOQOL-BREF) and the Geriatric Depression Scale, respectively. We performed a two-way analysis of variance (p ≤ 0.05). RESULTS: Only time effects were identified for overall quality of life, general health, and symptoms of depression. After the intervention, overall quality of life score increased (3.82 ± 0.95 versus 4.18 ± 0.53, p = 0.05), whereas symptoms of depression decreased (3.35 ± 1.73 versus 2.59 ± 1.54, p = 0.02) in the Exergame-based Training Group, and the general health improved in the Resistance Training Group (3.78 ± 0.81 versus 4.11 ± 0.68, p = 0.05) compared with the baseline scores. CONCLUSION: Both training groups improved different aspects of quality of life. The Exergaming-based Training Group improved the overall perception, whereas the Resistance Training Group improved the general health-related perception. Participants in the Exergame-based Training Group also decreased the number of symptoms of depression.

scholarly journals Predictors of change in quality of life in older adults with generalized anxiety disorder

2014 ◽  
Vol 27 (7) ◽  
pp. 1207-1215 ◽  
Author(s):  
Srijana Shrestha ◽  
Melinda A. Stanley ◽  
Nancy L. Wilson ◽  
Jeffrey A. Cully ◽  
Mark E. Kunik ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Older Adults ◽  
Clinical Trial ◽  
Anxiety Disorder ◽  
Randomized Clinical Trial ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Over Time

ABSTRACTBackground:Quality of life (QOL) is lower in older adults with generalized anxiety disorder (GAD). QOL generally improves following cognitive-behavioral treatment for GAD. Little is known, however, about additional variables predicting changes in QOL in older adults with GAD. This study examined predictors of change in QOL among older participants in a randomized clinical trial of cognitive behavioral therapy (CBT) for GAD, relative to enhanced usual care (EUC).Methods:Hierarchical multilevel mixed-model analyses were used to examine inter-individual and intra-individual factors that predicted QOL over time. Predictors were categorized into treatment, personal and clinical characteristics.Results:QOL improved over time, and there was significant variability between participants in change in QOL. Controlling for treatment condition, baseline general self-efficacy, baseline social support, within-person variation in worry and depression and average levels of depression across different time points predicted changes in QOL.Conclusions:QOL has increasingly been used as an outcome measure in treatment outcome studies to focus on overall improvement in functioning. Attention to improvement in symptoms of depression and worry, along with psychosocial variables, such as social support and self-efficacy, may help improve QOL in older adults with GAD.This study was a secondary study of data from a randomized clinical trial (NCT00308724) registered with clinical.trials.gov.

scholarly journals Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study

2022 ◽  
Vol 3 ◽  
Author(s):  
Deepthi Thumuluri ◽  
Robert Lyday ◽  
Phyllis Babcock ◽  
Edward H. Ip ◽  
Robert A. Kraft ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Older Adults ◽  
Clinical Trial ◽  
Pilot Study ◽  
Social Engagement ◽  
Early Stage ◽  
Brain Network ◽  
Dance Intervention

Alzheimer's disease has profound effects on quality of life, affecting not only cognition, but mobility and opportunities for social engagement. Dance is a form of movement that may be uniquely suited to help maintain quality of life for older adults, including those with dementia, because it inherently incorporates movement, social engagement, and cognitive stimulation. Here, we describe the methods and results of the pilot study for the IMOVE trial (NCT03333837, www.clinicaltrials.gov), a clinical trial designed to use improvisational dance classes to test the effects of movement and social engagement in people with mild cognitive impairment (MCI) or early-stage dementia. The pilot study was an 8-week investigation into the feasibility and potential effects of an improvisational dance intervention on people with MCI or early-stage dementia (PWD/MCI) and their caregivers (CG). The pilot aimed to assess changes in quality of life, balance, mood, and functional brain networks in PWD/MCI and their CG. Participants were recruited as dyads (pairs) that included one PWD/MCI and one CG. Ten total dyads were enrolled in the pilot study with five dyads assigned to the usual care control group and five dyads participating in the dance intervention. The intervention arm met twice weekly for 60 min for 8 weeks. Attendance and quality of life assessed with the Quality of Life in Alzheimer's disease (QoL-AD) questionnaire were the primary outcomes. Secondary outcomes included balance, mood and brain network connectivity assessed through graph theory analysis of functional magnetic resonance imaging (fMRI). Class attendance was 96% and qualitative feedback reflected participants felt socially connected to the group. Increases in quality of life and balance were observed, but not mood. Brain imaging analysis showed increases in multiple brain network characteristics, including global efficiency and modularity. Further investigation into the positive effects of this dance intervention on both imaging and non-imaging metrics will be carried out on the full clinical trial data. Results from the trial are expected in the summer of 2022.

scholarly journals The effects on pain, physical function, and quality of life of quadriceps strengthening exercises combined with Baduanjin qigong in older adults with knee osteoarthritis: a quasi-experimental study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Fenglan Wang ◽  
Xiaoli Zhang ◽  
Xiao Tong ◽  
Min Zhang ◽  
Fengmei Xing ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Knee Osteoarthritis ◽  
Pain Intensity ◽  
Physical Function ◽  
Self Efficacy ◽  
Strengthening Exercises ◽  
Quasi Experimental

Abstract Background Exercise is recommended as a principal treatment for individuals with knee osteoarthritis (KOA). However, the best choice for an optimal exercise program able to promote long-term compliance in KOA patients is not clear. This study aims to compare the effect of combined exercise (CE: quadriceps strengthening exercises (QSE) and Baduanjin qigong training (BDJ)) versus QSE alone and BDJ alone on older adults with KOA. Methods A three-arm, quasi-experimental trial with repeated measurements was used. As a cluster randomized trial, participants from three community centers were assigned respectively to QSE group, BDJ group and CE group. We assessed pain intensity, physical function, self-efficacy, and health-related quality-of-life (HRQoL) using standardized instruments at baseline, 3 months and 6 months follow-up. Results One hundred and twenty-eight participants with KOA aged over 60 completed the study. Over the 6 months, there were significant group interaction effects on pain intensity (F = 28.888, P < 0.001), physical function (F = 26.646, P < 0.001), and self-efficacy (F = 22.359, P < 0.001), and, based on a short form-12 item health survey questionnaire (SF-12), physical component summary (F = 7.470, P < 0.001), and mental component summary (F = 10.207, P < 0.001). Overall, the CE group exhibited significantly greater improvement in all outcomes when compared to the QSE group and the BDJ group. Conclusions CE treatment is more effective than QSE and BDJ in pain relief, increasing physical function, improving self-efficacy, and raising quality-of-life in community-dwelling KOA older adults. Moreover, it promotes long-term compliance in KOA community patients. Trial registration Chinese Clinical Trails Registry number ChiCTR2000033387 (retrospectively registered). Registered 30 May 2020.

scholarly journals Ultra-Reiz Current Appears to be More Effective Modality than Interferential for People with Knee Osteoarthritis: A Randomized Block Clinical Trial

2020 ◽  
Vol 1 (2) ◽  
pp. 29-34
Author(s):  
Mahnaz Ahangari ◽  
Amin Norouzi Fashkhami ◽  
Hamid Zinalpoor ◽  
Hamed Ahangari ◽  
Mohamad Reza Minator Sajjadi
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Knee Osteoarthritis ◽  
Life Quality ◽  
P Value ◽  
Recreational Activity ◽  
Knee Oa ◽  
Interferential Current ◽  
Pain Symptoms

Introduction: Today, increased degenerative disease of the knee, which reduces the efficiency of the activity and quality of life, is one of the most common causes of many population complaints. It is important to properly plan and carry out non-invasive and non-pharmacological therapies to treat the pain and its consequences.  The question of which of methods effectively relieves pain, improve function and efficiently increases life quality led to a comparison of two methods, interferential and ultra-reiz (Träbert) currents therapy. Methods: Randomized Block clinical trial carried out at Taleghani general hospital Shahid Beheshti University of Medical Sciences from November 2017 to February 2019. The study included 104 patients of both sexes, aged 38-74 years, with knee osteoarthritis. They were selected based on exclusion and inclusion criteria. The patients were randomly assigned to two groups: A and B.  Group A, n: 52 patients, were received ultra-reiz current, and group B, n: 52 patients, were subjected to interferential current. Parameters assessment were evaluated by the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire with 5 domains:  pain, symptoms, ADL, sports/recreational activity, and quality of life. Data were collected at the 1st session and at the end of treatment (at least three times a week). The obtained results were subject to statistical analysis. Results: Data were analyzed in SPSS software by using paired and two independent sample t-test. The mean scores before and after treatment with p-value range 0.002~0.764 showed that there were differences in pain, other symptoms, ADL, sport/recreational activity, and quality of life status between ultra-reiz and IFT groups, but the results were statistically more significant in the ultra-reiz group (p < 0.0001). Conclusions: Our study showed that ultra-reiz and IFT were effective for patients with knee OA, but ultra-reiz became a more effective modality than IFT in OA patients.

scholarly journals The Effectiveness of the Stepping-On Fall Prevention Program on the Quality of Life, Fear of Fall, and Fall-Preventive Behaviors Among Community-Dwelling Older Adults: A Randomized Clinical Trial

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sakineh Gholamzadeh ◽  
Maryam Ebrahimi ◽  
Nasrin Sharifi ◽  
Masoumeh Rambod
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Clinical Trial ◽  
Fall Prevention ◽  
The Elderly ◽  
Community Dwelling ◽  
Preventive Behaviors ◽  
Significant Difference ◽  
Community Dwelling Older Adults

Background: Along with increasing population of the elderly in various countries, the incidence of falls and respective damages has also increased. Objectives: Given the numerous disagreements regarding the effectiveness of different interventions mentioned in various sources, the present study aimed to examine the effectiveness of the Stepping-On fall preventive program on the quality of life, fear of fall, and fall-preventive behaviors among community-dwelling older adults in Shiraz, Iran. Methods: This study is a single-blinded randomized interventional or clinical trial study conducted on 90 elderly people under the coverage of two large health centers during 2019 - 2020 in Shiraz, Iran. Multi-stage randomized sampling was used to select the participants who were randomly allocated to either of the intervention (n = 45) or control groups (n = 45). Data collection tools were the fall efficiency scale, fall prevention behaviors, and Lipad quality of life questionnaires. The intervention group participated in a 7-session Stepping-On program, while the control group received the same routine care. Collected data were analyzed with SPSS software version 22. Results: The findings indicated that the Stepping-On program was effective on the fear of falling scores (P = 0.008) and the quality of life of the elderly under study (P = 0.019) at follow-up time. However, there was no significant difference immediately after the intervention (P > 0.05). However, the mean score of fall-preventing behaviors increased during the course of the study and reached a significant level immediately after the study was conducted (P = 0.046) and the other two months later (P = 0.028). Conclusions: The Stepping-On program may apparently affect the study variables. Therefore, further research is suggested to confirm the effectiveness of this program so that it can be used across all healthcare centers for the elderly.

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