scholarly journals Antibacterial Efficacy of Acetone Soluble Oil of Azadirachta indica on Some Bacterial Strains

2018 ◽  
Vol 09 (08) ◽  
Author(s):  
Kumari R ◽  
Dubey RC ◽  
Kumar S
Keyword(s):  
Azadirachta Indica ◽  
Antibacterial Efficacy ◽  
Bacterial Strains

scholarly journals Antibacterial efficacy of Azadirachta indica, Mimusops elengi and 2% CHX on multispecies dentinal biofilm

2015 ◽  
Vol 18 (6) ◽  
pp. 461 ◽  
Author(s):  
KunjalS Mistry ◽  
Zarna Sanghvi ◽  
Girish Parmar ◽  
Samir Shah ◽  
Kasukurthi Pushpalatha
Keyword(s):  
Azadirachta Indica ◽  
Antibacterial Efficacy ◽  
Mimusops Elengi

scholarly journals Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains

2011 ◽  
Vol 1 (6) ◽  
pp. 452-455 ◽  
Author(s):  
Abdul Viqar Khan ◽  
Qamar Uddin Ahmed ◽  
M Ramzan Mir ◽  
Indu Shukla ◽  
Athar Ali Khan
Keyword(s):  
Melia Azedarach ◽  
Antibacterial Efficacy ◽  
Bacterial Strains ◽  
Seed Extracts

scholarly journals Genetic Diversity of Endophytic Bacillus strains (101 and 201) Isolated from Native Neem (Azadirachta indica L.) Plants of West Malaysia

2021 ◽  
Author(s):  
Vithiya Yoganathan ◽  
Kartikeya Tiwari
Keyword(s):  
Bioactive Compounds ◽  
Azadirachta Indica ◽  
Research Work ◽  
Bacterial Endophytes ◽  
Bacterial Strains ◽  
Neem Tree ◽  
Control Activity ◽  
Gram Staining ◽  
Tree Construction ◽  
Staining Protocol

Background: A large number of bioactive compounds are produced by neem tree (Azadirachta indica). The association between the neem tree and endophytes is not well explored in West Malaysia. Endophytes are the organisms that live inside the medicinal plants and produce bioactive compounds of medicinal importance. The present research work has been carried out to harness significant biocontrol activity showing endophytic bacterial strains. Methods: Screening for bacterial endophytes was performed by using surface sterilisation method. Sterile explants were placed on nutrient agar plates and incubated at 37oC. Plates were observed for the presence of endophytes surrounding the explants. The bacterial endophytes were identified microscopically by Gram staining protocol and molecular characterization was performed by amplification of 16 S rRNA and sequencing. Result: Twelve endophytic bacterial strains isolated in which, only two bacterial strains were found significant in terms of bio-control activity. Therefore, these two bacterial strains were selected for further study. The 16S rRNA amplification and phylogenetic tree construction of endophytic bacterial strains (101 and 201) confirmed that these bacterial strains are closest with Bacillus cereus and Bacillus megaterium strains. 

scholarly journals COMPARATIVE ANALYSIS OF PHYTOCHEMICAL, ANTIBACTERIAL, AND ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF AZADIRACHTA INDICA LEAVES

2019 ◽  
pp. 151-154
Author(s):  
GAURAV SHARMA ◽  
ANKITA THAKUR ◽  
SOHAN LAL ◽  
ROHIT KUMAR NADDA
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate ◽  
Azadirachta Indica ◽  
Comparative Evaluation ◽  
Ethyl Acetate Extract ◽  
Radical Scavenging ◽  
Dpph Radical ◽  
Bacterial Strains ◽  
Dpph Radical Scavenging ◽  
Radical Scavenging Assay

Objective: The objective of the present study was the analysis of phytochemicals in various extracts of Azadirachta indica leaves, comparative evaluation of antibacterial activity of the various extracts of A. indica leaves against Escherichia coli and Staphylococcus aureus, and comparative evaluation of antioxidant activity in various extracts of A. indica leaves using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Methods: Various extracts were prepared by crushing the samples. Antibacterial susceptibility test, various phytochemical tests for qualitative analysis, and DPPH radical scavenging assay for antioxidant activity were performed. Results: The result suggested that alkaloids, flavonoids, and terpenoids were present in all the four extracts. Tannins were absent in the ethyl acetate extract, and phenols were only present in the ethyl acetate extract. Sterols and phlobatannins were absent in all the four extracts. Saponins were only present in the aqueous extract, and amino acids were only present in the ethyl acetate extract. The bacterial strains S. aureus and E. coli were used against the different extracts of A. indica leaves, i.e., methanol, chloroform, ethyl acetate, and aqueous. Conclusion: The results suggested that bioactive compounds found in leaves of A. indica contribute to its pharmacological activities.

scholarly journals Efficacy of Syrian Propolis Against Several Bacterial Strains

2020 ◽  
pp. 1-2
Author(s):  
Rim M Harfouch ◽  
◽  
Rawan Fead ◽  
Lubana Hammoud ◽  
◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Ethyl Acetate ◽  
Methanolic Extract ◽  
Natural Material ◽  
Klebsiella Pneumonia ◽  
Antibacterial Efficacy ◽  
Bacterial Strains ◽  
Different Strains

Propolis is a natural material that can be found in bee honey. It has many medical uses due to its antibacterial activity. In this study we aimed to estimate the antibacterial efficacy of three propolis extracts using three different solvents (Ethanol, Methanol and Ethyl Acetate). We experienced the three extracts on four different strains of bacteria (Klebsiella pneumonia, Ecoli, Pseudomonas aruginosa & Staphylococcus aureus). The results indicated that all the studied propolis extractions do not have any efficacy on Klebsiella neither on Ecoli. The methanolic extract has the greatest effect on Staphylococcus aureus as well as on Pseudomonas aruginosa in contrast of ethanolic and ethyle acetatic extracts which has no efficacy on any of the studied bacterial strains.

scholarly journals Biosynthesized Silver Nanoparticles Using an Aqueous Root Extract of Iris germanica as a Reducing Agent and Its Antibacterial Efficacy

2020 ◽  
pp. 1-10
Author(s):  
Vaghela Hiral ◽  
Shah Rahul ◽  
Vajapara Shailesh ◽  
Pathan Amanullakhan
Keyword(s):  
Silver Nanoparticles ◽  
Research Area ◽  
Reduction Reaction ◽  
Reducing Agent ◽  
Biomedical Science ◽  
Root Extract ◽  
Antibacterial Efficacy ◽  
Bacterial Strains ◽  
Iris Germanica ◽  
Aqueous Root Extract

Biosynthesized silver nanoparticles (AgNPs) are environment friendly, cost-effective, bio-compatible and expanding research area due to their potential applications in medical domain. The present study focuses on biologically synthesized of AgNPs using aqueous root extract of  Iris germanica as reducing agent as well as capping agent and examined their potential antibacterial efficacy. In reduction reaction it was observed that silver (Ag+1) ions associate in root extract and reduced in solution (Ag0) leads to formation of stable formation of spherical AgNPs. Biosynthesized AgNPs showed an effective and rapid antibacterial activity against both bacterial strain (gram+ve and gram-ve). Results exhibited that AgNPs were extremely toxic towards Bacillus subtilis and Escherichia coli pathogenic bacterial strains and can be utilized for the applications in biomedical science.

scholarly journals Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Lili He ◽  
Lijuan Zhai ◽  
Jian Sun ◽  
Jingwen Ji ◽  
Jinbo Ji ◽  
...  
Keyword(s):  
Antibacterial Activities ◽  
Multidrug Resistant ◽  
Gram Negative Bacteria ◽  
Antibacterial Efficacy ◽  
Clinical Use ◽  
Bacterial Strains ◽  
Antibiotic Drug ◽  
Clinical Interest ◽  
Derivatives Of

Background. Owing to the intrinsic stability against common β-lactamases and metallo-lactamases, monobactams gathered special attention in antibiotic drug development. However, so far, aztreonam is the only monobactam approved by FDA for clinical use. We designed new derivatives of aztreonam to enhance its antibacterial efficacy. Methods. We synthesized a series of monocyclic β-lactams by modifying mainly at the C3 position of azetidinone ring. NH2 group at C3 of azetidinone was attached to thiazole and thiadiazole which in turn was linked to nitrogenous heterocyclic rings via amidine moieties. We then investigated the in vitro antibacterial activities of synthesized compounds against ten bacterial strains of clinical interest in comparison to aztreonam and ceftazidime. Results. All compounds showed improved antibacterial activities against tested strains compared to reference drugs. Compounds 14d and 14e were most potent and showed the highest potency against all bacterial strains, with MIC values ranging from 0.25 µg/mL to 8 µg/mL, as compared to aztreonam (MIC 16 µg/mL to >64 µg/mL) and ceftazidime (MIC >64 µg/mL). These compounds (14d and 14e) may be valuable lead targets against multidrug-resistant Gram-negative bacteria.

Sign in / Sign up

Export Citation Format

Share Document