scholarly journals The Effects of Cigarette Smoking on Serum Carboxyhemoglobin and Calcium Levels in Apparently Healthy Male Smokers in Benin City, Nigeria

2022 ◽  
Vol 15 (01) ◽  
pp. 26-35
Author(s):  
Grace Umahi-Ottah ◽  
Babatunde Ishola Gabriel Adejumo ◽  
Elvis Osamede Godwins ◽  
Uchechukwu Dimkpa ◽  
Simon Uzor ◽  
...  
2018 ◽  
Vol 13 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Mehboba Ferdous ◽  
Sultana Ferdousi

Background: Cigarette smoking is associated with various forms of acute cardiac events such as myocardial infarction and ventricular fibrillation etc.Objective: To observe immediate impact of cigarette smoking on power spectral measures of heart rate variability (HRV) in current apparently healthy male regular cigarette smokers.Methods: This study was carried out on 120 apparently healthy male current regular cigarette smoker aged 20-55 years. To watch the intense impacts, data were recorded 5 and 30 min after completing a full stick of cigarette. Power spectral measures of HRV were recorded by a RMS digital polyrite D. Statistical analysis was done by paired sample t test.Results: LF power, LF nu & LF/HF ratio were significantly increased and HF power & HF nu were significantly decreased from their corresponding baseline value just 5 minutes after smoking and returned close to their baseline value after 30 minutes of smoking.Conclusion: The result of the study concludes that acceleration of sympathetic activity with simultaneous withdrawn of cardiovascular vagal adjustment happens quickly in the wake of smoking a cigarette.J Bangladesh Soc Physiol. 2018, June; 13(1): 8-12


2015 ◽  
Vol 9 (2) ◽  
pp. 59-64 ◽  
Author(s):  
Mehboba Ferdous ◽  
Sultana Ferdousi

Background:Cigarette smoking induced increased sympathetic activity is one of the major independent risk factor for cardiac morbidity and mortality. Objective:To assess acute effects of smoking on neuro cardiovascular regulation by analysis of time domain measures of HRV in current regular healthy male cigarette smoker. Methods:This comparative analytical study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from July 2011 to June 2012. 120 apparently healthy male current regular cigarette smoker aged 20-55 years were participated in the study group. Age and BMI matched 70 apparently healthy male non smoker subjects were studied as control. To observe the acute effects data were recorded 5 and 30 min after finishing a cigarette. Time domain measures of HRV were recorded by a RMS digital polyrite D. Statistical analysis was done by independent sample t test and paired sample t test. Results: Resting pulse rate, SBP, DBP, mean heart rate were significantly higher (p<0.001) and mean R-R interval, SDNN, RMSSD and total power were significantly lower (p<0.001) in all smokers in comparison to those of healthy control.In addition, all time domain parameters were significantly decreased from their corresponding baseline value just 5 minutes after smoking and returned close to their baseline value after 30 minutes of smoking but it remained significantly lower than control value. Conclusion: The result of this study concludes that cigarette smoking had acute effect on cardiac autonomic function causing depressed vagal activity and overbalance of sympathetic function. DOI: http://dx.doi.org/10.3329/jbsp.v9i2.22798 Bangladesh Soc Physiol. 2014, December; 9(2): 59-64


Author(s):  
Analike Rosemary Adamma ◽  
Emekwue Loveth ◽  
Ogbodo Emmanuel Chukwuemeka ◽  
Ezeugwunne Ifeoma Priscilla ◽  
Onoh Joy Obioma ◽  
...  

The use of Cannabis sativa is on the increase worldwide especially among adolescents and youths. This study investigated the effect of cannabis smoking on renal functions in young and apparently healthy male students of Nnamdi Azikiwe University, Nnewi campus, Anambra state, Nigeria. A total of 60 male (40 cannabis smokers and 20 controls) subjects participated in this study. A well-structured questionnaire was used to obtain the demographic data and anthropometric of subjects. Thereafter, 5mls of fasting blood sample was collected from the subjects into plain container for the estimation of biochemical parameters (creatinine, urea, uric acid, electrolytes). Renal parameters were estimated using standard methods. Data obtained were statistically analyzed using paired student t-test and pearson r correlation. Result showed that the mean serum levels of urea, creatinine, K+, Na+, Cl-, ionized calcium, total calcium, total carbon dioxide, anion gap, and pH were not significantly different in both smokers and control subjects(p>0.05). However, there was significantly higher mean serum level of uric acid (2.42 ± 38.54 vs 1.92 ± 41.61; p<0.05) and total calcium (16.0 ± 0.30 vs 10.24 ± 0.18; p<0.05) in smokers compared with control subjects. Again, BMI was significantly higher in smokers compared with non-smokers (23.96 ± 3.15; p<0.05 Vs 21.95 ± 2.17; p<0.05). Therefore, cannabis use had no deleterious effect on the kidneys, but the significantly higher uric acid levels in the smokers may provide some anti-oxidant protection. However, further studies are necessary to further unravel the full potentials of cannabis use.


2012 ◽  
Vol 2 (3) ◽  
pp. 181-184 ◽  
Author(s):  
Rashmi Narayanrao Gitte

Objective: Cigarette smoking is one of the major lifestyle factors influencing the health of human beings. Fibrinogen is the major plasma protein coagulation factor. Higher plasma fibrinogen concentrations are associated with cardiovascular diseases. Material & Methods: One hundred twenty healthy male smokers and one hundred twenty healthy male non-smokers among hospital employees and people from surrounding areas of Narayana Medical College, Nellore (India) were studied. The platelet count was done using Beckman Coulter Automatic Analyzer; AcT 5diffCP.Assay for plasma fibrinogen was performed using turbido-metric immunoassay. Results: The mean plasma fibrinogen concentration for smokers is 3.78 gms/L and for non-smokers 3.02 gms/L. The mean platelet count for smokers is 257325 per mm3 and for non-smokers 215483.3 per mm3. The difference between mean plasma fibrinogen and platelet count of smokers and non-smokers was statistically significant (p<0.0001). Conclusion: Thus we concluded that in smokers plasma fibrinogen concentration and platelet count increase significantly. Regular monitoring of these two parameters in smokers is advised DOI: http://dx.doi.org/10.3126/ajms.v2i3.4261 Asian Journal of Medical Sciences 2 (2011) 181-184  


1970 ◽  
Vol 2 ◽  
pp. 49-53 ◽  
Author(s):  
Mohammed Montasir Islam ◽  
Md Ruhul Amin ◽  
Shameema Begum ◽  
Dilruba Akther ◽  
Abedur Rahman

The present study was carried out to observe the changes in total count in WBC in cigarette smokers. The study population consisted of 105 adult male smokers and non-smokers, aged 20~40 years, from different socio-economic classes. Among them, 30 apparently healthy non-smokers were taken as control. 75 apparently healthy smokers, who had the history of smoking of one or more cigarette per day, regularly for at least last one year, were taken as the study group. Smokers were again subdivided into three categories according to the number of cigarettes they consumed per day. For statistical analysis unpaired ‘t' test was used for comparison. Mean ± SD of Total count of WBC in non smokers and smokers were 7501.66 ± 929.4 /mm3 and 9171.3 ± 1037.7/mm3 respectively. Smokers had significantly (P<0.001) higher WBC counts than non-smokers. In addition, WBC count was found increased with intensity of smoking. The smokers who were smoking e 20 cigarettes per day had the higher total WBC count than those who were smoking lesser. The findings of the present study suggest that cigarette smoking may cause increased the total count of WBC, which may predict high risk for some fatal diseases. Key words: Cigarette Smoking; White Blood Cell; Adult Male DOI:10.3329/jbsp.v2i0.985 J Bangladesh Soc Physiol. 2007 Dec;(2): 49-53


2020 ◽  
Vol 48 ◽  
pp. 101928 ◽  
Author(s):  
Erika Cosset ◽  
Tieng Vannary ◽  
Frédérique Sloan-Béna ◽  
Stefania Gimelli ◽  
Eric Gerstel ◽  
...  

1979 ◽  
Author(s):  
F.C. Chao ◽  
J.L. Tullis ◽  
C.A. Alper ◽  
J. E. Silbert

Normal plasma contains nonsedlmentable platelet factor-3 (NS-PF3) activity, thought to be caused by circulating platelet membrane fragments. Stypven time (ST), an assay for PF-3 activity, of plasma prepared by differential centrifugation and by filtration through 0.22 μ Millipore filters were Investigated. The average ST for platelet-rich plasma (PRP), low-spin platelet-poor plasma (LSPPP), medium-spin PPP (MSPPP), high-spin PPP (HSPPP) and filtered PPP (FPPP) was 28.0, 40.4, 43.4, 61.7 and 65.5 sec, respectively (27 determinations). Filtration of plasma did not affect factor V and X activities. Material eluted from filters after filtration of plasma consisted of membrane vesicles with high PF-3 activity. ST were then measured in plasma preparations obtained from smoking (S) (>15 cigarettes/day) and nonsmoking (NS) healthy male individuals, ages (A) between 45-64. Data obtained were grouped according to age and smoking habits (Gr. I, 9 S, A 45-64; Gr. II, 14 NS, A 45-54; Gr. III, 7 S, A 55-64; Gr. IV, 14 S, A 55-64) and subjected to two-way analysis variance employing the BMDP2V program. Significant shortening of ST was noted in LSPPP (p<0.02) and MSPPP (p<0.02) in smoking groups which, however, showed no significant differences in PRP (p>0.8), HSPPP (p>0.06) and FPPP (p>0.4). Results suggest smoking individuals exhibit significantly higher NS-PF3 activity in plasma.


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