Histopathological characteristics of breast carcinomas at the Olabisi Onabanjo University Teaching Hospital, Sagamu Ogun State, Nigeria

Author(s):  
A A Banjo ◽  
O Musa ◽  
A O Tade ◽  
BA Ayoade ◽  
A O Daramola ◽  
...  
2020 ◽  
Vol 3 (1) ◽  
pp. 67-72
Author(s):  
Olufemi Adebawojo ◽  
Adebayo Akadri ◽  
John Imaralu

Objective: To determine the prevalence and outcome of hypertensive disorder of pregnancy in Babcock University Teaching Hospital, Ilishan-Remo, Ogun State Nigeria Method: This was a retrospective descriptive study of all documented cases of hypertensive disorder of pregnancy between the 1st of June 2012 and 31st May, 2017. Information such as age, parity, booking status, level of education, blood pressure at presentation, urinalysis at presentation, gestational age at presentation, and delivery, mode of delivery, baby’s birth weight was extracted from patients’ case files. Result: There were 1,118 deliveries during the study period out of which 55 (4.9%) patients had hypertensive disorders in pregnancy. The mean age was 31.5years ±48.1 and mean parity, 1.2± 1.1.  The mean systolic and diastolic blood pressures were 180.4 ± 1.88mmHg and 105.1± 1.5mmHg, respectively. Thirty-four (75.5%) of the women had preeclampsia/ eclampsia, while 7 (15.5%) had gestational hypertension. Most women were delivered preterm (22 patients, 48.7%).  The majority of them (33, 73.3%) were delivered by cesarean section, out of which 2 (4.4%) were elective cesarean section and 31 patients (68.8%) were emergency cesarean section. The case fatality rate was 1.8%. Conclusion: Pre-eclampsia was the most prevalent t hypertensive disorder of pregnancy.  It was more prevalent among primigravidae patients and the most common complication was preterm delivery. Strengthening antenatal care services will enable early identification of cases. Prompt referral of cases for specialist care will help in reducing the adverse outcomes associated with the condition.


2021 ◽  
Vol 07 (02) ◽  
pp. 076-081
Author(s):  
Daniel Ayodele Sanni ◽  
Abiodun Olaniyi Popoola ◽  
Nasiru Akanmu Ibrahim ◽  
Foluso Oyeropo Omodele ◽  
Festus Edobor Emiogun ◽  
...  

AbstractBreast carcinoma is a disease of utmost concern to the individual, family, and society at large. The current trend in the management of breast carcinoma also involves hormonal therapy. Consequently, the hormone expression of the tumor in the individual involved must be known if he or she is to benefit from such therapy. This is a prospective study of estrogen and progesterone receptors as well as Her-2/neu overexpression in all breast carcinomas seen at the Lagos State University Teaching Hospital, Ikeja, Nigeria, between April, 1, 2016, and September, 30, 2018. The total number of cases analyzed during the period under study was 107, comprising 105 women and 2 men with an age range of 26 to 88 years and a mean age of 52 ± 13 years. The tumors fell into histologic grade II (71.0%) and grade III (29.0%). They expressed ER, PR, and Her-2/neu positivity in 42.1%, 33.6%, and 30.8% of the cases, respectively. Triple-negative breast cancer was 35.5%. Male breast cancers presented as invasive ductal carcinoma and exhibit similar staining pattern as the female breast cancer. In conclusion, this study shows that breast carcinomas occurred predominantly in females of younger age and present with tumors, most of which were of high grade and exhibit triple negativity. This observation is relevant to any therapeutic decisions and management of these patients. Improvement in breast carcinoma screening programs so that the disease can be detected early is also advocated.


2021 ◽  
Vol 4 (1) ◽  
pp. 38-44
Author(s):  
John Ogunkoya ◽  
Akolade Idowu ◽  
Charles John Elikwu ◽  
Titus Oyedele ◽  
Akindele Ladele ◽  
...  

Coronavirus infection became a global pandemic in March 2020. The number of hospitalized cases in Nigeria and Ogun State has been on a steady increase with a concomitant rise in Mortality. This necessitates a coordinated and a more systemic approach in the management of this deadly disease. As a result of the potential effects of the disease on the socio-economic development of Ogun State, the state government granted Babcock University Teaching Hospital, Ilishan-Remo the permission to diagnose, admit and manage cases in line with Nigeria Centre for Disease Control (NCDC)/World Health Organization (WHO) guidelines. This led to the establishment of a molecular laboratory and a COVID-19 task force to oversee the treatment of confirmed cases of COVID-19 disease. This protocol is developed to serve as a template for the diagnosis, admission, treatment of cases of COVID-19 diseases presenting for care in the hospital and to prevent the spread of the disease among healthcare workers within the hospital environment.


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