scholarly journals COMPARATIVE CLINICAL STUDY OF KUMARIKA VATI AND MEFENAMIC ACID IN UDAVARTINI YONIVYAPAD (SPASMODIC DYSMENORRHEA)

2021 ◽  
Vol 9 (12) ◽  
pp. 2933-2941
Author(s):  
Rashmi Verma ◽  
Supriya M ◽  
Shobha Mattur
Keyword(s):  
Mefenamic Acid ◽  
Repeated Measures ◽  
Symptomatic Relief ◽  
Statistical Test ◽  
Common Cause ◽  
Pain Duration ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Equal Effectiveness

Menstruation is a normal physiological process when it is accompanied by pain is called Dysmenorrhea. It is one of the commonest gynaecological complaints. Dysmenorrhea is painful menstruation, which is the pratyatma lax- ana of Udavartini yoni vyapad i.e., spasmodic dysmenorrhea. It is a common cause of distress in women. Here the main reason for pain is the vitiation of vata dosha (apana vata), viloma/pratiloma gati leading to vedna yukta artava munchan and to manage this pratiloma vata, one needs to use drugs that have anulomana properties and vedna samak. Kumarika vati is used as vedana shamaka aushadha to give symptomatic relief. Hence the topic was selected for the study. Objectives: To compare the effect of Kumarika Vati with Mefenamic Acid in the man- agement of Udavartini Yonivyapad (Spasmodic Dysmenorrhea). Materials & Methods: 20 patients of Group A were treated with Kumarika Vati, a dose of 250mg BD 5 days before menstruation & 5 days during menstruation. 20 patients of Group B were treated with a Mefenamic Acid dose of 250mg BD for 3 days during menstruation. Result: The data of both groups were collected according to the objective and subjective parameters and analyzed using the most appropriate statistical test (repeated measures of ANOVA test and Mann –Whitney U test). The efficacy is statically significant within the group at P<0.001 and statistically insignificant between the group at P>0.05 among all the parameters. Interpretation and Conclusion: On comparison of Kumarika Vati with Mefenamic acid both have equal effectiveness in relieving the pain intensity, pain duration, site of pain, nature of pain and associated complaints. Keywords: Udavartini Yoni Vyapad, Dysmenorrhea, Kumarika Vati, Mefenamic Acid.

scholarly journals An Open Labelled Comparative Clinical Study to Evaluate the Effect of Go-Ghrita Tarpana and Triphala-Ghrita Tarpana on Antero-Posterior Diameter in Axial-Myopia

AYUSHDHARA ◽  
2021 ◽  
pp. 3384-3396
Author(s):  
Tarun Kumar Dwibedi ◽  
Veerayya R Hiremath ◽  
Shashikala K ◽  
Gururaj N
Keyword(s):  
Repeated Measures ◽  
Optical Glass ◽  
Optical Correction ◽  
Comparative Clinical Study ◽  
Group A ◽  
Bonferroni Test ◽  
The Difference ◽  
Group B ◽  
Equal Effectiveness ◽  
Axial Myopia

Background and Objective: Axial-myopia is characterized by blurriness of vision for distance caused by increased in A-P diameter. Usual treatment for myopia is optical correction by optical glass and contact lens. To restore distance vision, surgical intervention like, LASIK is adopted, which has complications like dry eye syndrome and astigmatism. The Ayurvedic approach of the disease mainly concentrates on treating the disease and preventing the progression of the disease. There are many hypothetical theories regarding mode of action of Tarpana on Myopia and Timira. In this study, an attempt is made to observe the effect of Tarpana on A-P diameter of eyeball and to know the difference between Tarpana by plain Go-Ghrita and Triphala Ghrita. Materials and Methods: 20 patients of Group A, were treated with Go-Ghrita Tarpana (two sittings of 7 days each, with the gap of 14 days) and in Group B, 20 patients were treated with Triphala-Ghrita Tarpana (two sittings of 7 days each, with the gap of 14 days). Results: The data of both the groups were collected according to the objective and subjective parameters and analyzed using the most appropriate statistical test (repeated measures of ANOVA, Bonferroni Test and Mann- Whitney U Test). The efficacy is statistically significant within the group at P <0.001and statistically insignificant between the groups at P >0.05 among all the parameters. Interpretation and Conclusion: On comparison of Go-Ghrita Tarpana with Triphala-Ghrita Tarpana, both have an equal effectiveness on distant vision, Optical correction and A-P diameter.

scholarly journals A Comparative Clinical Study on the Effect of Dhanyaka Kalka and Dhanyaka Avalehya with Anupana of Sharkara mixed Tandulodaka in Garbhini Chardi

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Upasana Nath ◽  
Kalpana Sharma
Keyword(s):  
Clinical Study ◽  
Large Scale ◽  
Symptomatic Relief ◽  
First Trimester ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Rice Water ◽  
Trial Drug ◽  
In Pregnancy

Garbhini Chardi (vomiting in pregnancy) is a blazing issue in obstetric enactment. About 50-60% of all pregnant females agonize from vomiting in pregnancy most apparently in first trimester. If not tackled effectively before or in time, it may affect the quality of life of pregnant woman and pregnancy consequences. Ayurvedic classics have described many formulations for management of Garbhini Chardi. In this study Dhanyaka kalka and Dhanyaka Avaleha was taken both with Anupana of Sharkara mixed Tandulodaka. Aim: To compare the effect of Dhanyaka Kalka and Dhanyaka Avaleha with Anupana of Sharkara mixed with Tandulodaka in Garbhini Chardi. Materials and Methods: Single blind clinical study with pre‑test and post‑test was designed. 60 patients complaining of Chardi in 1st trimester were randomly divided into the two groups: Group A and Group B, each comprising of 30 patients. Medicine used for Group A was Dhanyaka Kalka with Anupana of Sharkara Mixed Tandulodaka (rice, water or gruel) and medicine used for Group B was Dhanyaka Avaleha with Anupana of Sharkara mixed Tandulodaka. Those cases, which were in regular follow ups for 5 weeks were taken for clinical study. The criteria of assessment were mainly on the symptomatic relief. Intermediate follow ups were recorded at interval of two weeks. Results: In Group A, overall percentage relief in chief complains was calculated as 59.44% whereas in Group B this value was 66.5%. Conclusion: In present clinical study efficacy of Dhanyaka Avaleha has been proven beneficial in comparison to Dhanyaka Kalka. The trial drug is highly significant in the management of Garbhini Chardi. This study needs to be done on large scale and for longer duration.

Comparative Clinical study of Jatyadi Taila and Jatyadi Ghrita in the management of Dushta Vrana

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar
Keyword(s):  
Clinical Study ◽  
Burning Sensation ◽  
Normal Process ◽  
Surgical Practice ◽  
Local Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Contaminated Wound ◽  
Group B

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

Evaluation of comparative efficacy of Guda Sunthi and Manjistha Guggulu Avapeedana Nasya in Manyastambha (Cervical Spondylitis)

2019 ◽  
Vol 4 (02) ◽  
Author(s):  
Manjunath Akki ◽  
Suresh Hakkandi ◽  
Arti Panwar
Keyword(s):  
Complete Remission ◽  
Routine Activities ◽  
Household Work ◽  
Comparative Efficacy ◽  
Exclusion Criteria ◽  
Patient Complaints ◽  
The People ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Manyastambha is described under Nanatmaja Vatavyadhi. It is a condition where, the aggravated Vata get localized in the Manya Pradesha causing symptoms like Stambha and Shoola. Manyastambha can be compared with earliest symptoms of cervical spondylitis. In this condition, patient complaints of neck pain. The neck is held rigidly and neck movements may exacerbate pain. Now a day, Cervical spondylitis is very common in the people who do routine activities like travelling, household work, desk job etc. It can be seen in people as early as 25 years of age. In Manyastambha, Nasya is the main line of treatment. (i.e. Vatakaphahara Nasya). Objectives: To evaluate the comparative efficacy of Guda Sunthi Avapeedana Nasya and Manjistha Guggulu Avpeedana Nasya in Manyastambha (Cervical Spondylitis). Materials and Methods: This is a comparative clinical study conducted to assess the efficacy in Manyastambha. As per the inclusion and exclusion criteria, the patients who fulfill the criteria were randomly selected and equally divided into two groups. Group A - 15 Patients received Guda-Sunthi Avapeedana Nasya. Group B - 15 Patients received Manjistha-Guggulu Avapeedana Nasya. Results and Conclusion: In Group A, 9 patients (60%) showed complete remission and 6 patients (30%) showed marked response. In Group B, 3 patients (20%) showed complete remission, 1 patient (7%) showed marked response. 6 patients (30%) showed moderate response, 4 patients (26%) showed mild response and 1 patient (7%) showed unchanged response.

scholarly journals A Randomized Comparative Clinical Study to evaluate the effect of Bodhi Vruksha Twak Kashaya with Madhu and Guduchi Kashaya in the Management of Vatarakta with special reference to Gouty Arthritis

2020 ◽  
Vol 5 (02) ◽  
pp. 22-29
Author(s):  
K. M. Bhavana ◽  
Umesh C. ◽  
Neelakanta Sajjanar ◽  
Gopala Krishna G.
Keyword(s):  
Special Reference ◽  
Gouty Arthritis ◽  
Signs And Symptoms ◽  
Renal Diseases ◽  
Comparative Clinical Study ◽  
Evolution Of Technology ◽  
Group A ◽  
Group B ◽  
Contemporary Medicine ◽  
Potential Signal

Background: Vatarakta is a disease which is said to affect the population indulging in sedentary lifestyle. In today’s era the evolution of technology has reached a point where pretty much anything is available at the touch of a button. The lifestyle of today’s population is breeding ground for diseases like Vatarakta. Based on the causes, signs and symptoms, Vatarakta may be correlated to gouty arthritis in contemporary medicine. Gout affects about 2.1 million worldwide. Its prevalence is increasing; moreover it is a potential signal for unrecognized co-morbidities like obesity, diabetes mellitus, hypertension and renal diseases. In India the prevalence of gout is 2-6 per 1000. The purpose of this study is to explore and find out an effective, less expensive, easily available and well accepted drug with minimal or no complications for this dreadful condition. Materials and Methods: 40 patients diagnosed with Vatarakta w.s.r Gouty Arthritis were assigned randomly into 2 groups. Group A, were administered Bodhi Vruksha Twak Kashaya 50ml B.I.D with Madhu and Group B were administered Guduchi Kashaya 50ml B.I.D for a duration of 30 days. Assessment was done on day 0, day 15, day 30, and day 45. Observations and Results: In the present study Group A showed statistical significant results in all the parameters except for Sandhishotha and group B showed statistical significant result in Sandhishoola, Sandhidaha, Sparshasahaishnuta and uric acid levels. Conclusion: Overall result shows patients treated with Guduchi Kashaya showed better results than patients treated with Bodhi Vruksha Twak Kashaya with Madhu in Vatarakta with special reference to Gouty Arthritis.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF ASHTAVARGAM KASHAYA AND GANDHARVAHASTHADI KASHAYA IN THE MANAGEMENT OF KATIGRAHA w.s.r. TO LUMBAR SPONDYLOSIS

2020 ◽  
Vol 8 (8) ◽  
pp. 4036-4042
Author(s):  
Abeena Raj D P ◽  
Shripathi Acharya
Keyword(s):  
Clinical Study ◽  
Food Habits ◽  
Unhealthy Food ◽  
Lumbar Spondylosis ◽  
Moderate Improvement ◽  
Nutritional Deficit ◽  
Mild Improvement ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Katigraha is a condition in which the vitiated Vata is localizing in the Katipradesha and producing stiff-ness and pain. These symptoms are similar to Lumbar Spondylosis. The degenerative changes due to aging or trauma, changing in lifestyle & work pattern, unhealthy food habits causing nutritional deficit etc., are causing Dhatukshaya and Margavarodha. Here Ashtavarga & Gandharvahasthadi Kashayas are taken to evaluate the effect on Katigraha. Totally 40 patients of Katigraha were selected, divided in to two groups equally. Group A treated with Ashtavargamkashaya and Group B treated with Gandharvahasthadi Kashaya for 30 days. In group A, 55% patients got moderate improvement and 40% patients with mild im-provement in group B, 5%got moderate improvement and 60% got mild improvement. It is concluded that in general statistically significant results were seen in both the groups. AshtavargamKashaya showed better efficacy than Gandharvahasthadikashaya.

scholarly journals A comparative clinical study on the effect of Gudashunti Nasya and Kola Kulattadi Ruksha Sweda in Manyasthamba

2020 ◽  
Vol 5 (03) ◽  
pp. 1-6
Author(s):  
Sandeep K ◽  
Guruprasad G ◽  
Veeraj Hegde
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Severe Pain ◽  
Computer Usage ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Classical Symptom

Due to present day lifestyle, a greater number of people are inclined to desk work and computer usage leading to many disorders. Manyasthamba is one among such disorders where the stiffness of neck with severe pain is the classical symptom which hampers our day to day life. While explaining treatment of Manyasthamba our Acharyas explained Rukshasweda and Nasya Karma as main line of treatment. Here a study was done by taking Gudashunti Yoga explained in Sharangadara Samhita indicated for Nasya and Kolakulattadi Churna indicated in Vatavyadhi explained in Ashtanga Sangraha for Ruksha Churna Sweda. A comparative clinical study of 40 patients suffering from Manyastambha were selected after thorough investigation. Patients were subjected to Nasya Karma in Group A and Ruksha Sweda and Nasya Karma in Group B for 7 days. Patients were assessed based on standard parameters before and after treatment and 7 days follow up. The statistical analysis revealed that there was a significant improvement in parameters like pain and stiffness. Hence proving the efficacy in the condition.

scholarly journals A comparative clinical study to access the role of Basti and Virechana Karma followed by Rasayana in post menopausal Asthikshaya (Osteoporosis)

2020 ◽  
Vol 5 (05) ◽  
pp. 96-103
Author(s):  
Deepa S. Patil ◽  
Prashanth A.S
Keyword(s):  
Clinical Study ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Post Menopausal ◽  
Group B

Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.

scholarly journals A Comparative Clinical Study of Trikarshika Kwatha with and without Lifestyle Modification in the Management of Vatarakta with Special Reference to Hyperuricaemia

2021 ◽  
pp. 10-19
Author(s):  
Md Tanzil Ansari ◽  
Sukumar Ghosh ◽  
Shailendra Kumar Singh
Keyword(s):  
Clinical Study ◽  
Lifestyle Modification ◽  
Test Results ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
High Level ◽  
Urate Crystals

Nowadays, people are more vulnerable to metabolic disorders due to their faulty dietary and behavioural habits. One such disorder is Vatarakta which causes functional impairment due to involvement of Sandhi (joints). It is manifested by Ruk, Toda, Sparsha asahatva, Shopha, Raga, Daha and Stabdhata in Sandhi. Vatarakta can be correlated with Hyperuricaemia or Gout due to similarity in their clinical features. Hyperuricaemia is defined as abnormally high level of uric acid in blood (i.e. >6mg/dl in female and >7mg/dl in male). On the other hand, Gout is an inflammatory response to monosodium urate crystals formed secondary to hyperuricaemia. Aims and objectives: 1. To evaluate the effectiveness of Trikarshika kwatha and lifestyle modification in the management of Vatarakta. 2. To compare the effects of Trikarshika kwatha with and without lifestyle modification in the management of Vatarakta. Materials and methods: Raw herbs of the research formulation were collected after proper identification and Kwatha was prepared for oral administration. For the clinical study, total 60 patients were selected on the basis of selection criteria. Selected patients were randomly divided into two groups. (i) Group A: 30 patients were treated with Trikarshika kwatha. (ii) Group B: 30 patients were treated with Trikarshika kwatha along with Lifestyle modification. Individual patient was treated for 45 days along with follow up at the interval of every 15 days. To assess the effectiveness of treatment, scoring pattern was followed for subjective and objective parameters. They were assessed before and after treatment. The collected data were analysed statistically by using Paired t-test. Results: On the basis of all statistical data, it can be said that patients of Group B showed better results in all parameters in comparison to patients of Group A. Conclusion: Both Trikarshika kwatha and Lifestyle modification are affective but Trikarshika kwatha with Lifestyle modification is more effective than Trikarshika kwatha without Lifestyle modification in the management of Vatarakta.

scholarly journals Randomised trial of mefenamic acid versus tranexamic acid in management of menorrhagia

2017 ◽  
Vol 6 (10) ◽  
pp. 4608
Author(s):  
Madhu J. ◽  
Shylaja A. S.
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Mefenamic Acid ◽  
Randomised Trial ◽  
Menstrual Blood ◽  
Menstrual Blood Loss ◽  
Loss Assessment ◽  
Group A ◽  
Group B ◽  
To Receive

Background: The objective of the study was to compare the efficacy of mefenamic acid, a non-inflammatory drug with tranexamic acid, an antifibrinolytic drug in management of menorrhaghia.Methods: Randomised trial of women attending outpatient department of St. Philomena’s hospital, Bangalore with complaints of menorrhagia. Fifty four patients with complaints of menorrhagia were randomly assigned to receive either mefenamic acid 500 mg tid (group A- 24 patients) or tranexamic acid 1 gm TID (group B- 26 patients) from day one to day five for three consecutive menstrual cycles.Results: Reduction in menstrual blood loss as assessed by pictoral blood loss assessment chart was more in group B (50%) than in Group A (30%) (ANOVA, covariates with F=59.647, p<0.001). Difference in improvement of dysmenorrhoea was not statistically significant (p=0.640). Side effects were less in group B compared to group A (p=0.271). Post treatment Hb% significantly improved in both groups (p=0.015 in group A, p<0.001 in gr B). Acceptability was statistically similar in both groups (p>0.05).Conclusions: Both mefenamic acid and tranexamic acid were effective in management of menorrhagia. Tranexamic acid was significantly superior to mefenamic acid in terms of reduction in menstrual blood loss.

Sign in / Sign up

Export Citation Format

Share Document