scholarly journals MANAGEMENT OF HYPERTENSION - AN AYURVEDIC REVIEW

2021 ◽  
Vol 9 (10) ◽  
pp. 2465-2471
Author(s):  
Garima Yadav ◽  
Pramod Kumar Mishra ◽  
Indu Sharma ◽  
Lekha Soni
Keyword(s):  
Blood Pressure ◽  
Dietary Habits ◽  
Antihypertensive Drugs ◽  
Medical Condition ◽  
Premature Death ◽  
Cost Effective ◽  
Systemic Blood Pressure ◽  
Arterial Disease ◽  
Treatment Modalities ◽  
Human Beings

Hypertension is the most common lifestyle disorder today. Systemic arterial hypertension is that the most important modifiable risk factor for all-cause morbidity and mortality. Worldwide one of the major causes of premature death is hypertension and can lead to major health consequences, such as CHD, CHF, peripheral arterial disease, stroke, renal failure, and death. Hypertension may be a chronic and sometimes asymptomatic medical condition during which systemic blood pressure is elevated beyond normal. Fewer than half of those with hypertension are conscious of their condition and lots of others are Modern treatment modalities are effective for the management of hypertension but pose human beings to their unwanted complications on their long-term use. The conventional antihypertensive drugs have many adverse effects & are not well tolerated which led to non-compliance, switching & discontinuation of treatment. There is no direct description of HTN in Ayurveda but based on its clinical presentation and similarity between pathogenesis factors for hypertension can be correlated with Raktagata Vata and it is considered as Tridoshaja Vyadhi. Treatment for hypertension in Ayurveda on the idea of Balancing all three Doshas. So Nidan Parivarajan, proper dietary habits, Yoga, Meditation along Ayurvedic herbs can be beneficial for balancing the state of mind, maintaining as well asreducing blood pressure. The Ayurvedic drug's potency depends upon rasa, Guna, Virya, Vipaka & Prabhava. Also, Acharyas have mentioned this as Prabhava of the drug. Ayurveda has various classical formulations and single herbs like Brahmi, Pushkarmoola, Jyotishamati, Sarpagandha, Saunf, Jatamansi etc. having Hridya, Kaphahara, Vatahara, Balya, Raktaprasadana, etc. properties which are safe and cost-effective too. Keywords: High Blood Pressure, Lifestyle disorders, Raktachapa, Silent killer.

Burning issues in blood pressure control

2019 ◽  
Vol 61 (2) ◽  
pp. 24-26
Author(s):  
J. A. Ker ◽  
K. Outhoff
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Treatment Guidelines ◽  
Premature Death ◽  
Pressure Control ◽  
Arterial Disease ◽  
Elevated Blood ◽  
Optimal Blood Pressure ◽  
Peripheral Arterial ◽  
Ageing Populations

Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure (BP) is the leading cause of premature death and morbidity due to stroke and ischemic heart disease. Hypertension is also a major risk factor for heart failure, atrial fibrillation, chronic kidney disease, peripheral arterial disease and cognitive decline. This article discusses the current evidencebased treatment guidelines and pressing temporal issues in optimal blood pressure control.

A comparative study of monotherapy versus combination therapy in patients with stage-1 hypertension in terms of efficacy and cost effectiveness and to assess the medication adherence

2018 ◽  
Vol 9 (1) ◽  
pp. 147 ◽  
Author(s):  
Ritu A Mathew ◽  
Samuel Johnson ◽  
Shalumol Jose ◽  
Shampa Chakraborty ◽  
Kenneth N ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Medication Adherence ◽  
Combination Therapy ◽  
Antihypertensive Drugs ◽  
Angiotensin Receptor Blockers ◽  
Financial Burden ◽  
Cost Effective ◽  
Dual Therapy ◽  
Individual Therapy ◽  
Stage 1

Hypertension has multiple pathogenesis and majority of patients require two or more antihypertensive drugs to provide optimum control of blood pressure. The aim is to compare the effectiveness of mono therapy versus combination therapy in patients with stage-1 hypertension, to assess the medication adherence and to compare the cost incurred per day for the different therapies. Patient’s demographical details and history was recorded in a data entry form. Outcome of the treatment was measured in terms of reduction in systolic and diastolic blood pressure. Patient’s medication adherence was assessed using modified Medication Adherence Scale. Economic outcomes were measured in terms of cost of individual therapy. The data was entered into the excel sheet and statistically analysed using ANOVA. Results showed that dual therapy is the most effective in reducing the mean systolic (28.75 mm Hg) and diastolic (8.875) blood pressure with the combination of Amlodipine + Telmisartan being the most effective. Here, 66 patients (33%) were found to be adherent and 134 patients (67%) were found to be non- adherent. It was found that AMLOKIND 2.5, LOSAKIND and ATEN 50 were the most cost effective brands of drug from the classes of calcium channel blockers, angiotensin receptor blockers and beta blockers respectively. Comparison of effectiveness of various antihypertensive therapies showed that dual therapy shows maximum reduction in mean systolic BP and thus it can be prescribed more often in Stage I hypertensive patients. The poor adherence scores indicate that a multidisciplinary approach with a greater involvement of the patient is required to increase the compliance of the patient. Also cost effective drugs need to be prescribed more in order to decrease the financial burden on the patients. Keywords: Blood pressure; Monotherapy; Dual therapy; Triple therapy; Medication adherence

scholarly journals HYPERTENSION: AN AYURVEDIC PERSPECTIVE

2021 ◽  
Vol 9 (8) ◽  
pp. 1748-1753
Author(s):  
Anshika Rao
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Antihypertensive Drugs ◽  
Medical Condition ◽  
Good Health ◽  
Chronic Medical Condition ◽  
Public Health Issue ◽  
Arterial Blood ◽  
Prime Concern ◽  
The World

Hypertension (HTN) is a major public health issue worldwide, because of its high prevalence and concomitant increase in the risk of disease. In the contemporary situation Hypertension is the most critical disease in the world. If we focus on the present situation then we can see that due to rapid globalization we are facing Hypertension. Due to rapid modernization, people are leading more stressful lives. As a result, hypertension is one of the wide- spread disorders which came across in practice. Ab. India is labelled as the global capital of hypertension. Nowa- days, not only lifestyle disorders are becoming more common, but they are also affecting younger populations. Hence, the population at risk shifts from 40+ to maybe 30+ or even younger. Hypertension results from a variety of reasons like stress, obesity, genetic factors, overuse of the salts in the diet and ageing etc. As we all know, Hy- pertension is called a silent killer because it rarely exhibits symptoms before it damages the heart, brain or kidney. Though a lot of potent antihypertensive drugs are available today in modern medicine, none of them is free from untoward effects. The principal focus of Ayurveda is on maintaining good health and adopting a healthy way of life. In Ayurveda, there is no description of such a single disease that can resemble hypertension. As per Ayurve- dic principles, in case of an unknown disease, the physician should try to understand the nature of the disease through Dosha, Dushya and Samprapti; then should initiate the treatment. So, it becomes our prime concern to understand hypertension thoroughly with an Ayurvedic perspective. Hypertension (HTN or HT), also known as High blood pressure or arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is persistently elevated. Hypertension is one of the major causes of cardiovascular morbidity and mortalityworldwide. It is a global health problem affecting people of different ethnicity and ages around the world. It is an asymptomatic medical condition in which systemic arterial blood pressure is elevated beyond the normal value. Keywords: High Blood Pressure, Lifestyle disorders, Silent killer.

scholarly journals Methods of defining hypertension in electronic medical records: validation against national survey data

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Mingkai Peng ◽  
Guanmin Chen ◽  
Gilaad Kaplan ◽  
Lisa Lix ◽  
Neil Drummond ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Drug ◽  
Medical Records ◽  
Antihypertensive Drugs ◽  
Cost Effective ◽  
Drug Prescriptions ◽  
Health Improvement ◽  
Diagnosis Code ◽  
Treatment Rate ◽  
Case Definitions

ABSTRACTObjectivesElectronic medical records (EMR) can be a cost-effective source for hypertension surveillance. However, diagnosis of hypertension in EMR is commonly under-coded and warrants the needs to review blood pressure and antihypertensive drugs for hypertension case identification. To advocate for the use of EMR data for research, we developed methods for defining hypertension using diagnosis codes, blood pressure measurements and antihypertensive drug prescriptionApproachWe included all the patients actively registered in The Health Improvement Network (THIN) database, UK, on 31 December 2011. Three case definitions using diagnosis code, antihypertensive drug prescriptions and abnormal blood pressure, respectively, were used to identify hypertension patients. We compared the prevalence and treatment rate of hypertension in THIN with results from Health Survey for England (HSE) in 2011. ResultsCompared with prevalence reported by HSE (29.7%), the use of diagnosis code alone (14.0%) underestimated hypertension prevalence. The use of any of the definitions (38.4%) or the combination of antihypertensive drug prescriptions and abnormal blood pressure (38.4%) had the higher prevalence than HSE. The use of diagnosis code or two abnormal blood pressure records within a 2-year period (31.1%) had similar prevalence and treatment rate of hypertension with HSE. ConclusionsDifferent definitions should be used for different study purposes. The definition of ‘diagnosis code or two abnormal blood pressure records with a 2-year period’ could be used for hypertension surveillance in THIN.

scholarly journals Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR

1998 ◽  
Vol 275 (4) ◽  
pp. F576-F584 ◽  
Author(s):  
Fred Ivan Kvam ◽  
Jarle Ofstad ◽  
Bjarne M. Iversen
Keyword(s):  
Blood Pressure ◽  
Calcium Channel ◽  
Capillary Pressure ◽  
Enzyme Inhibitor ◽  
Antihypertensive Drugs ◽  
Pressure Control ◽  
Systemic Blood Pressure ◽  
Calcium Channel Antagonists ◽  
Glomerular Capillary ◽  
Glomerular Capillary Pressure

The relationship between systemic blood pressure and glomerular capillary pressure (Pgc) in spontaneously hypertensive rats (SHR) during treatment with antihypertensive drugs is still unclear. The effects of an angiotensin-converting enzyme inhibitor (enalapril), two calcium channel antagonists (nifedipine and verapamil), and an α1-receptor blocker (doxazosin) on renal blood flow (RBF) autoregulation, Pgc, and renal segmental resistances were therefore studied in SHR. Recordings of RBF autoregulation were done before and 30 min after intravenous infusion of the different drugs, and Pgcwas thereafter measured with the stop-flow technique. When the mean arterial pressure (MAP) was reduced to ∼120 mmHg by infusions of doxazosin or enalapril, the lower pressure limit of RBF autoregulation was reduced significantly. Nifedipine or verapamil abolished RBF autoregulation. Doxazosin did not change Pgc (43.6 ± 1.4 vs. 46.7 ± 1.5 mmHg in controls, P > 0.5), enalapril lowered (41.3 ± 0.8 mmHg, P < 0.01), and the calcium channel antagonists increased Pgc[53.7 ± 1.4 mmHg (nifedipine) and 54.8 ± 1.2 mmHg (verapamil), P < 0.01]. When MAP was reduced to ∼85 mmHg by drugs, Pgc was reduced to 43.3 ± 1.7 mmHg after nifedipine ( P > 0.2 vs. control), whereas Pgc after enalapril was 38.5 ± 0.5 mmHg ( P < 0.05 vs. control). Enalapril reduced Pgc mainly by reducing efferent resistance. During treatment with calcium channel antagonists, Pgc became strictly dependent on MAP. Monotherapy with nifedipine may increase Pgc and by this mechanism accelerate glomerulosclerosis if a strict blood pressure control is not obtained.

scholarly journals Burning issues in blood pressure control

2020 ◽  
pp. 107-109
Author(s):  
JA Ker ◽  
K Outhoff
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Treatment Guidelines ◽  
Premature Death ◽  
Pressure Control ◽  
Arterial Disease ◽  
Current Evidence ◽  
Optimal Blood Pressure ◽  
Peripheral Arterial ◽  
Ageing Populations

Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure (BP) is the leading cause of premature death and morbidity due to stroke and ischemic heart disease. Hypertension is also a major risk factor for heart failure, atrial fibrillation, chronic kidney disease, peripheral arterial disease and cognitive decline. This article discusses the current evidence-based treatment guidelines and pressing temporal issues in optimal blood pressure control.

scholarly journals PROFIL PASIEN HIPERTENSI DI POLIKLINIK GINJAL-HIPERTENSI

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marillyn M. Tamburian ◽  
Emma Sy. Moeis ◽  
Fandy Gosal
Keyword(s):  
Blood Pressure ◽  
Retrospective Study ◽  
General Hospital ◽  
Medical Records ◽  
Causes Of Death ◽  
Antihypertensive Drugs ◽  
Medical Condition ◽  
Hypertensive Patients ◽  
Hypertension Clinic ◽  
Diastolic Hypertension

Abstract : Hypertension is chrocnic medical condition which the blood pressure has elevated above 140mmHg systolic and 90 mmHg diastolic. Hypertension is one of top 10 of the causes of death worldwide. It is because hypertension affects in damaged of some organs like heart, brain, renal, retinal, ect.The purpose of this study is to give the information about profile of hypertensive patients and about antihypertensive drugs which most commonly used in Prof. Dr. R. D. Kandou General Hospital Manado.This is descriptive retrospective study. The data had been taken from medical records in Nephrology and Hypertension Clinic at Prof. Dr. R. D. Kandou General Hospital Manado.Keywords : Hypertension, Complication, Antihypertensive drugsAbstrak : Hipertensi merupakan kondisi dimana tekanan darah sistol diatas 140 mmHg dan tekanan darah diastol diatas 90 mmHg.Hipertensi menjadi salah satu penyebab kematian terbanyak didunia karena hipertensi dapat mempengaruhi kerusakan pada organ-organ target yang lain seperti organ jantung, otak, ginjal, mata dan lain-lain.Tujuan penelitian ini untuk memberikan gambaran tentang profil pasien hipertensi serta jenis obat antihipertensi yang digunakan di poliklinik ginjal-hipertensi RSUP Prof. Dr. R. D. Kandou Manado periode Oktober 2014 - Maret 2015.Penelitian ini merupakan jenis penelitian deskriptif retrospektif dengan data sekunder di poliklinik ginjal-hipertensi RSUP. Prof. Dr. R. D. Kandou Manado periode Oktober 2014 - Maret 2015. Sampel penelitian sebanyak 311 pasien.Kata Kunci : Hipertensi, Komplikasi, Obat Antihipertensi

Efficacy and safety of fixed-dose Lercanidipine-Enalapril for the treatment of hypertension

2009 ◽  
Vol 1 ◽  
pp. CMT.S2315
Author(s):  
Christos Chatzikyrkou ◽  
Hermann Haller ◽  
Jan Menne
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Drugs ◽  
Premature Death ◽  
Risk Groups ◽  
Developed Countries ◽  
Fixed Dose ◽  
Blood Pressure Targets ◽  
Cardiovascular Morbidity And Mortality ◽  
Treatment Of Hypertension ◽  
Multiple Drugs

Hypertension is the most important preventable cause of premature death in the developed countries, and the benefits of antihypertensive drugs regarding cardiovascular morbidity and mortality are well established. Nevertheless, adequate control is achieved only in the minority of patients. All official guidelines recommend blood pressure targets of 140/90 mmHg in every patient and even lower in high-risk groups, and support the use of two of more drugs as initial therapy in specific populations. Multiple drugs acting by different, but complementary, mechanisms of action are increasingly implemented in the treatment of hypertension and fixed-dose combinations are gaining popularity. Simplifying therapy is particularly important for elderly patients, who are more likely to have co-morbid conditions and to be taking multiple medications. The once-daily administration of a fixed dose enalapril/lercanidipine effectively reduces blood pressure in patients inadequately controlled by either component, is generally well tolerated and exhibits a favourable metabolic profile.

Influence of melatonin on blood pressure indicators with different severity of desynchronosis

2020 ◽  
pp. 30-40
Author(s):  
M. G. Melnik
Keyword(s):  
Blood Pressure ◽  
Circadian Rhythms ◽  
Antihypertensive Drugs ◽  
Blood Pressure Monitoring ◽  
Home Monitoring ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Pronounced Decrease ◽  
The Third ◽  
Pressure Indicators

Purpose. To study the dynamics of blood pressure (BP) indicators under the influence of exogenously administered melatonin (Melatonin-SZ, Severnaya Zvezda, Russia) with various manifestations of desynchronosis of circadian BP rhythms (arterial hypertension – AH, high normal blood pressure) to determine the scheme of their effective compensation. Material and methods. The study included 101 patients with desynchronosis of circadian rhythms of blood pressure – 52 patients with hypertension, constituting the first and second groups, and 49 individuals with high normal blood pressure, representing the third and fourth groups. Patients of the second and fourth groups received conservative therapy, patients of the first and third groups combined it with melatonin. All patients underwent measurements of office blood pressure, home monitoring of blood pressure (ABPM), electrocardiography, 24-hour blood pressure monitoring (ABPM). Results and discussion. In patients of the first and third groups, compared with the traditional treatment groups, by the end of the observation period, a significantly (p < 0.05) decrease in office systolic blood pressure (SBP) / diastolic blood pressure (DBP) was established: in the first group compared with the second – 1.11 / 1.13 times, in the third group compared to the fourth – 1.43 / 1.58 times; significantly more (p < 0.05) pronounced decrease in SBP / DBP during DMAD – by 1.08 / 1.17 and 1.58 / 1.62 times, respectively, Significantly (p < 0.05) more pronounced decrease in average daily, average daily and average nighttime SBP / DBP during ABPM – by 1.13 / 1.20, 1.11 / 1.20, 1.23 / 1.25 and 1.47 / 1.31, 1.42 / 1.19, 1.54 / 1.41 times, respectively; reliably (p < 0.05) more frequent registration of the dipper rhythm type SBP / DBP – 1.6 / 1.4 and 1.6 / 1.4 times, respectively. In addition, the dynamics of patients in the first and third groups showed a significant (p < 0.05) decrease in the mean daily and mean nighttime SBP / DBP variability (SBP in the first group by 27.3 and 41.3 %, respectively; DBP in the first group by 20.1 and 26.3 %, respectively; SBP in the third group by 13.5 and 25.2 %, respectively; DBP in the third group by 12.2 and 28.2 %, respectively). Conclusions. With various manifestations of desynchronosis of circadian rhythms of blood pressure (AH, high normal blood pressure), the prescription of melatonin (Melatonin-SZ, Severnaya Zvezda, Russia) at a dose of 3 mg per day 30–40 minutes before bedtime for a month against the background of non-drug therapy and antihypertensive drugs led to a significantly more effective decrease in blood pressure at its office measurement, DMAD, ABPM with an improvement in the circadian rhythm of blood pressure and normalization of blood pressure variability.

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