CLINICAL STUDY ON URINARY TRACT INFECTION WITH SPECIAL REFERENCE TO BACTERIOLOGY AND THEIR SENSITIVITY PATTERN IN A TERTIARY CARE CENTRE OF NORTH-BENGAL

2021 ◽  
pp. 44-46
Author(s):  
Achintya Narayan Ray ◽  
Sandip Saha ◽  
Smarajit Banik ◽  
Biplab Mondal ◽  
O P. Pandey
Keyword(s):  
Urinary Tract ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Resistance Pattern ◽  
Tertiary Care Centre ◽  
Study Region ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
North Bengal

Background: Urinary tract infections (UTIs) are the most common bacterial infection encountered in tertiary care settings UTI is one of the most common bacterial infections in humans and a major cause of morbidity. Its antibiotic sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difcult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. This prospec Methods: tive and observational Study was conducted on patients attending the outpatient and indoor admitted patients at North Bengal Medical College at Darjeeling district of West Bengal. From 2016 to 2018. A total 100 patients were taken who having clinical features of UTI. The study region covers the various districts of North Bengal. Template was generated in MS excel sheet and analysis was done on SPSS 20.0 software. A Results: mong 100 UTI patients, 34 (34%) were male and 66 (66%) were female. The majority of patients (30%) were 46-60 yrs of age. In the study group symptomatic presentation in order of frequency were, dysuria 85%, urgency74%, fever with chill 60%, hypogastric pain and tenderness 70%, ank pain 30%. E.coli & klebsiella were most common isolates among i.e 66% and11.% respectively. Proteus were sensitive to Netlimycine 90%, Imipenem 87%, Meropenem 79%, Amikacin 75% Gentamycin 68 %, levooxacin 82 % of patients. In the present study, females (66%) Conclusions: were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin etc. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

Spectrum and Antibiotic Resistance Pattern of Bacteria Causing Urinary Tract Infections (UTI) in a Tertiary Care Hospital

2020 ◽  
Vol 23 (1) ◽  
pp. 13-18
Author(s):  
Sadia Afroz ◽  
Zakir Hossain Habib ◽  
Syed Muhammad Baqui Billah ◽  
Hasina Akhter ◽  
Hosne Jahan ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Current Knowledge ◽  
Clinical Sample ◽  
Evaluation Studies ◽  
Tertiary Care ◽  
Resistance Pattern ◽  
Care Hospital ◽  
Tract Infections

Background: Urinary tract infection (UTI) is one of the most common bacterial infections encountered by clinicians particularly in developing countries. Current knowledge on antimicrobial resistance pattern is essential for appropriate therapy. The aim of the present study was to identify the causative organisms for UTI and to determine the antibiotic susceptibility pattern of organisms causing UTI. Method: This cross sectional study was carried out in the department of Microbiology, Sir Salimullah Medical College, Dhaka, from a period of January 2014 to December 2014. Results: Out of 2136 clinical sample of urine, 430 (20.1%) showed significant bacterial growth. Escherichia coli was the commonest urinary pathogen (76.3%), followed by Pseudomonas spp. (7.9%), Proteus spp. (7.2%), Klebsiella spp., Citrobacter spp. (1.9% each) and Staphylococcus aureus (1.6%). Isolated uropathogens showed highest resistance for Amoxycillin (86%-97%) and Cefradin (71%-100%), resistance rate for other commonly used antimicrobial agents was high; Cefixime (52%-85%), Ceftriaxone (50%-71%), Ciprofloxacin (50%-88%), Cotrimoxazole (50%-75%), Gentamicin (57%-75%) and Nitrofurantoin (43%-100%), while uropathogens were least resistant to Imipenem (0%-15%) and Amikacin (0%-29%). Conclusion: Due to high degree of resistance to commonly used antimicrobials to treat UTI, routine monitoring and evaluation studies should be conducted to update physicians’ knowledge about most effective antibiotics for treatment of UTI. Journal of Surgical Sciences (2019) Vol. 23 (1) : 13-18

scholarly journals Isolation, identification and antibiotic sensitivity pattern of Escherichia coli isolated from various clinical sample in a tertiary care hospital, Jaipur, Rajasthan, India

2020 ◽  
Vol 8 (5) ◽  
pp. 1774
Author(s):  
Bitopan Das ◽  
Mrinmoy Sarma ◽  
Rohit Kumar ◽  
Palashi Borah ◽  
Sushama Sinha ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Clinical Sample ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Resistant Bacteria ◽  
Care Hospital ◽  
Sensitivity Pattern ◽  
Tract Infections

Background: Escherichia coli is one of the most frequent causes of many bacterial infections, including Urinary Tract Infections (UTI), blood stream infections, otitis media, pneumonia, meningitis, traveler’s diarrhoea, enteric infections and systemic infections. This study was done with the aim to surveying antibiotic sensitivity pattern of isolated Escherichia coli in both sex attended in NIMS Hospital, Jaipur under the taken time period.Methods: In this cross-sectional study, 62 Escherichia coli were isolated from various clinical specimens of the patients attending both OPD and IPD. The strains were selected using the laboratory standard methods and culture-specific. The antibiotic susceptibility testing was performed using Kirby-Bauer disk diffusion method.Results: Out of total 62 isolates of Escherichia coli 26(41.93%) isolates were from male while 36(58.064%) from female patients. Maximum sensitivity were shown by Polymyxin B and Colistin i.c 100% followed by Nitrofuratonin 82.5% followed by Meropenem 79.03%, Aztreonam 72.58%, Piperacillin/ Tazobactam and Ciprofloxacin 61.30%, each Amikacin 56.45%, Imipenem 54.83%, Ofloxacin 45.16%, Cefepime 43.54%, Ceftazidime 38.71%, Gentamycin and Ceftriaxone 37.09% each, Cefotaxime 30.64%, Norfloxacin 27.5%. Maximum resistance shown against Norfloxacin 72.5%, followed by Gentamycin and Ceftriaxone 62.90%, Ceftazidime 61.30%.Conclusions: Escherichia coli infected more in urinary tract infection as compare to other sample in human, and it is common in female than male. Regular monitoring of antimicrobial susceptibility for E.coli is recommended to improve treatment. A changing trend in antibiotic sensitivity profile of the isolates need to be monitored as there is limited availability of newer drugs and the emergence of resistant bacteria far exceeds the rate of new drug development.

scholarly journals Catheter associated urinary tract infection in an acute care setting of a tertiary care centre in South India

2019 ◽  
Vol 7 (6) ◽  
pp. 2182
Author(s):  
Debadutta Mishra ◽  
Kodukula Bhaskara Rao
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Demographic Data ◽  
Tertiary Care ◽  
Resistance Pattern ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Icu Patients ◽  
Acinetobacter Species ◽  
Tract Infections

Background: Catheter associated UTI is a serious cause of morbidity and mortality in intensive care unit (ICU) patients. Hence, authors undertook the present study to know the prevalence of catheter associated urinary tract infections (CAUTI) in medical ICU patients of tertiary care centre and to know the antibiotic resistance pattern of the causative organisms.Methods: A one-year prospective study was carried out from September 2015 to August 2016. Demographic data from the catheterized patients were collected daily and scrutinized for the signs and symptoms as per CDC criteria for confirmation as CAUTI. Relevant antimicrobial resistance data of etiologic agents were also collected to ascertain the prevalent resistance pattern.Results: The overall incidence of CAUTI was 14.69 per 1000 catheterized days in the present study. Out of the 37 diagnosed CAUTI cases, 12 (32.4%) were males and 25 (67.6%) were females with maximum patients being between 40 to 60 years of age. The commonest uropathogens was Escherichia coli (n=26) followed by K. pneumoniae (n=5). Both Escherichia coli and Klebsiella pneumoniae isolates were found to be 100% resistant to cefotaxime, ceftazidime and cefuroxime. Pseudomonas aeruginosa and Acinetobacter species were least common etiological culprits and demonstrated complete resistance to all the tested antibiotics.Conclusions: In the present study the prevalence of CAUTI is much higher which needs to be rectified by continuous monitoring and training of the staff in implementation of infection control practices in a proactive manner.

scholarly journals Prevalence of urinary tract infection and sensitivity pattern amongst children less than 3 years of age with fever in a tertiary care hospital in South Karnataka

2020 ◽  
Vol 9 (5) ◽  
pp. 736
Author(s):  
Jasmine John Ponvelil ◽  
Hema Narasimhe Gowda ◽  
Savitha Mysore Ram Raj
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tertiary Care ◽  
Colony Count ◽  
Resistance Pattern ◽  
Care Hospital ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Tract Infections

Background: Antimicrobial resistance is a major concern especially in urinary tract infections in children as improperly treated urinary tract infections (UTIs) on long term can cause renal scarring in young children, which leads to long term morbidities like hypertension, chronic renal disease and pre-eclampsia. The empirical therapy for UTI varies regionally due to their varied sensitivities and resistance pattern. This study aims to facilitate policy making in empirical antibiotic therapy of pediatric patients with urinary tract infections.Methods: A cross sectional study, which included a group of 140 children’s (6 months to 3 years) with fever were included in the study. All patients with colony count >1 lakh CFU/ml or colony count >50,000 CFU/ml, with leukocyturia (>5 WBCs/HPF in centrifuged urine) or colony count >1000 CFU/ml with urinary symptoms were diagnosed to be positive for urinary tract infection.Results: The prevalence of UTI in febrile children less than 3 years in our study was 0.1%. Out of 140 patients with fever, 35 were UTI positive. E. coli was the most commonly isolated organism (60%), followed by MRSA (14.2%) and Enterococci (11.4 %). E. coli was found to be most sensitive to nitrofurantoin (85.7%), followed by gentamicin (61.9%) and norfloxacin (38%). E. coli showed high resistance to cefuroxime (76.2%) and ceftriaxone (71.4%). MRSA was found to be most sensitive to linezolid and vancomycin, and resistant to norfloxacin.Conclusions: The data shows the increased resistance of E. coli to commonly prescribed antibiotics like cefuroxime and ceftriaxone. So, this study shows the empirical treatment of UTI in our region and the importance of having antibiotic prescription policies in every region.

scholarly journals Trend of Sensitivity Pattern of Uropathogenic Escherichia coli: Five Year Experience at a Tertiary Care Hospital in Dhaka

2013 ◽  
Vol 5 (2) ◽  
pp. 103-105
Author(s):  
Most. Fahmida Begum ◽  
Abu Syed Md. Mosaddek ◽  
Kawser Perveen ◽  
Rezina Karim ◽  
Nurun Nahar Begum
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections are among the most common bacterial infections caused by pathogens with a decreasing susceptibility to several classes of antimicrobials.Objective: The purpose of the present study was to see the trend of sensitivity pattern of Escherichia coli (E. coli) isolated from the urinary tract patients.Methodology: This retrospective study was conducted at Uttara Adhunik Medical College Hospital, Dhaka from 2008 to 2012 for a period of 5(five) years. All patients were within ages 1 month to 80 years, comprising of both male and female, either out or in patients were included as study population. Urine sample was collected and Escherichia coli was isolated and identified as well as the antimicrobial susceptibility patterns was determined.Results: A total number of 16,666 urine samples were collected. No significant changes of susceptibility pattern of Escherichia coli was found to ciprofloxacin, cephradine, ceftriaxone, levofloxacin,  nalidixic  acid,  imipenem  and  meropenem;  however,  significant  change  was  detected  to amoxicillin, amoxiclav, cefixime, trimethoprim-sulfamethoxazole, amikacin, ceftazidime and mecillinam between 2008 and 2012.Conclusion: Trend of sensitivity pattern of Escherichia coli is changing to few important antibiotics.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20766J Shaheed Suhrawardy Med Coll, 2013;5(2):103-105

scholarly journals Susceptibility of Urinary Tract Bacteria to Newer Antimicrobial Drugs

2016 ◽  
Vol 4 (1) ◽  
pp. 22-24
Author(s):  
Manjula Mehta ◽  
Jyoti Sharma ◽  
Sonia Bhardwaj
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Specific Treatment ◽  
Resistance Pattern ◽  
Antimicrobial Drugs ◽  
Economic Implications ◽  
E Coli ◽  
Tract Infections

Urinary tract infections (UTIs) are among the commonest types of bacterial infections. The antibiotic treatment for UTIs is associated with important medical and economic implications. Many different microorganisms can cause UTIs though the most common pathogens are E. coli and members of family Enterobacteriaceae. The knowledge of etiology and antibiotic resistance pattern of the organisms causing urinary tract infection is essential. The present study was undertaken to evaluate trends of antibiotic susceptibility of commonly isolated uropathogens using newer antimicrobial agents, prulifloxacin, fosfomycin (FOM) and doripenem. We conclude that maintaining a record of culture results and the antibiogram may help clinicians to determine the empirical and/or specific treatment based on the antibiogram of the isolate for better therapeutic outcome.

scholarly journals Urinary tract infections and antibiotic susceptibility among the patients attending B & D hospital of Lalitpur, Nepal

2016 ◽  
Vol 7 (5) ◽  
pp. 47-51 ◽  
Author(s):  
Yadav Prasad Joshi ◽  
Shreejeet Shrestha ◽  
Russell Kabir ◽  
Anita Thapa ◽  
Parbati Upreti ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Susceptibility ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Cross Sectional Study ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Cross Sectional ◽  
Tract Infections

Background:Urinary tract infection is the most common bacterial infections in humans and serious health problem in many parts of the world. It has become more complicated in treatment due to different pathogens and increasing resistant to antimicrobial agents. This study aims to investigate the prevalence of urinary tract infection and antibiotic susceptibility patterns of pathogens among the patients attending in B & B hospital Nepal.Materials and Methods:A hospital based cross sectional study was conducted in between April 2010 to March 2011. Urine samples were collected from clinically suspected patients and tested bacteriologically using standard procedures. Antimicrobial susceptibility test was performed for isolated pathogen using the Kirby-Bauer disk diffusion method according to Clinical and Laboratory Standards Institute guidelines.Results:Out of 1260 examined specimens 25.24 % were positive and majority 61.64% were females.  The most common pathogens isolated were Escherichia coli (66.67%), Enterococcus (7.55%) and Staphylococcus (6.60 %). The drug resistant among the positive cases were reported. The highest resistant of positive cases was found with Cefexime (87.88%) and Enterococcus with Ampicillin (66.67%) and Staphyllococcus with Cloxacillin (66.67%). The highest susceptibility was for Vancomycin and Ampicillin i.e. 33.33% in each.Conclusion:The findings showed that E. coli isolates were the predominant pathogen and the presence of bacterial isolates with very high resistance to the commonly prescribed drugs. As drug resistance among bacterial pathogens is an evolving process and serious issue. Therefore, routine surveillance and monitoring studies should be conducted to provide physicians knowledge on the updated and most effective empirical treatment of UTIs. Asian Journal of Medical Sciences Vol.7(5) 2016 47-51

Urinary tract infection

2017 ◽  
Author(s):  
Magnus Grabe ◽  
Björn Wullt
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Antimicrobial Agents ◽  
Antibiotic Sensitivity ◽  
Resistance Pattern ◽  
Sensitivity Testing ◽  
Efficient Treatment ◽  
Treatment Regimens ◽  
Recommended Treatment ◽  
Tract Infections

Infections of the urinary tract are among the most frequent infections encountered in the community and hospital environments. They range from harmless self-curing cystitis to severe pyelonephritis with life-threatening sepsis. Urinary tract infections are often recurrent. Host defence is crucial to control the infection but can also be deleterious in terms of scar formation. Early diagnosis, determination of severity, evaluation of possible risk factors, and assumption of possible pathogen are essential aspects to initiate efficient treatment. Urine culture with antibiotic sensitivity testing is the most important tool to confirm a suspected clinical diagnosis and direct treatment. Patients with urological disease are particularly susceptible to urinary tract infections, and healthcare-associated urinary infections are observed in approximately 10% of hospitalized urological patients. In view of the worsening resistance pattern of common urinary pathogens against available antimicrobial agents, it is important to comply with recommended treatment regimens.

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