scholarly journals AYURVEDIC MANAGEMENT OF SECONDARY INFERTILITY DUE TO POLYCYSTIC OVARIAN SYNDROME AND TUBAL BLOCK: A CASE STUDY

2021 ◽  
pp. 72-75
Author(s):  
Rineesha K.P ◽  
Asha. S.T
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Semen Analysis ◽  
Local Treatment ◽  
Secondary Infertility ◽  
Management Protocol ◽  
Tubal Blockage ◽  
History Of ◽  
Tubal Factor ◽  
Ayurvedic Treatment ◽  
Ovarian Syndrome

Secondary infertility is defined as the inability of a couple to conceive who had at least one prior conception. Ovarian factor and tubal factor are the most frequent causes of secondary infertility in woman. Polycystic Ovarian Syndrome is a common endocrinological disorder and it is characterized by menstrual irregularities and anovulation. It can be correlated with Nashtartava in Ayurveda. Tubal factor infertility occurs when an obstruction in fallopian tube and it can be correlated with Sanga srotodushti of Artavavaha srotas or Beejavaha srotas. A 36 year old female presented with a complaint of secondary infertility a diagnosed case of Polycystic Ovarian Syndrome and tubal block with a history of neonatal death due to preterm delivery at 24 week gestation and husband aged 38 year with normal semen analysis. The present case was treated on Ayurvedic management protocol including shodhana, samana therapies and uttaravasti. Treatment was started with Deepana - Pachana medicines. Then Udwarthanam, Virechanam, Mathra vasti and Uttaravasti were done which removes the srotorodha and helps in proper formation of each dhatu. Uttaravasti is the most effective local treatment in gynaecological disorders. Uttaravasti with hot potency medicine is very effective in treating tubal blockage. The outcome of the treatment resulted in twin pregnancy and delivered two female babies. So the present case signifies the fruitful outcome of Ayurvedic treatment in the field of infertility.    Keywords:  Secondary infertility, Polycystic Ovarian Syndrome, Tubal block, Nashtartava, Artavavaha srotas, Uttaravasti

Association between depression risk and polycystic ovarian syndrome in young women: a retrospective nationwide population-based cohort study (1998–2013)

2019 ◽  
Vol 34 (9) ◽  
pp. 1830-1837 ◽  
Author(s):  
Tomor Harnod ◽  
Weishan Chen ◽  
Jen-Hung Wang ◽  
Shinn-Zong Lin ◽  
Dah-Ching Ding
Keyword(s):  
Clinical Trial ◽  
Cohort Study ◽  
Polycystic Ovarian Syndrome ◽  
Population Based ◽  
Aged Patients ◽  
Depression Risk ◽  
Increased Risk ◽  
History Of ◽  
Competing Interest ◽  
Ovarian Syndrome

Abstract STUDY QUESTION Is polycystic ovarian syndrome (PCOS) in women associated with the increasing incidence of depression in an East Asian population? SUMMARY ANSWER Younger PCOS patients (aged 15–29 years), but not middle-aged patients, have an increased risk of depression in Taiwan. WHAT IS KNOWN ALREADY During reproductive age, 6–10% of women have PCOS. Among them, ~40% experience depression, mostly at young ages. STUDY DESIGN, SIZE, DURATION This is a retrospective population-based cohort study analysing depression risk in Taiwanese women using data from a nationwide database containing 1998–2013 data of nearly 1 million people. PARTICIPANTS/MATERIALS, SETTING, METHODS We included 15- to 50-year-old women newly diagnosed with PCOS during 1998–2013 from the Taiwan National Health Insurance Research Database as the PCOS cohort (n = 7684) and then randomly matched them 4 : 1 by sex, age and index year with women without PCOS as the comparison cohort (n = 30 736). We used multivariable Cox proportional hazard regression analysis to determine the association between PCOS and depression risk [hazard ratio (HR) with 95% confidence interval (CI)]. MAIN RESULTS AND THE ROLE OF CHANCE The incidence of depression was higher in the PCOS group than in the comparison group (6.67 vs. 4.82 per 1000 person-years; adjusted HR = 1.28, 95% CI = 1.12–1.46). PCOS patients aged 15–29 years had a significantly higher depression risk (adjusted HR = 1.39, 95% CI = 1.18–1.65); no such significant association was noted among patients aged 30–39 years and 40–50 years. LIMITATIONS, REASONS FOR CAUTION A history of malignancy, which may increase depression, could not be obtained for our study patients. Moreover, we could not obtain a family history of depression, a relevant risk factor for depression. Finally, the database has no records of body mass index, which may influence depression outcome. WIDER IMPLICATIONS OF THE FINDINGS In Taiwan, younger PCOS patients (15–29 years), but not the middle-aged patients, have an increased risk of depression. Our findings provide vital information to patients, clinicians, the Taiwan Government and other developing Asian countries to improve the PCOS treatment strategies in the future. Routine screening for depression in PCOS patients may be implemented into the health practice. STUDY FUNDING/COMPETING INTEREST(S) This study was supported in part by the Taiwan Ministry of Health and Welfare Clinical Trial Center (MOHW108-TDU-B-212-133 004), China Medical University Hospital, Academia Sinica Stroke Biosignature Project (BM10701010021), MOST Clinical Trial Consortium for Stroke (MOST 107-2321-B-039 -004-), Tseng-Lien Lin Foundation, Taichung, Taiwan and Katsuzo and Kiyo Aoshima Memorial Funds, Japan. No competing interest existed. TRIAL REGISTRATION NUMBER N/A.

Association of thrombophilia and polycystic ovarian syndrome in women with history of recurrent pregnancy loss

2012 ◽  
Vol 28 (8) ◽  
pp. 590-593 ◽  
Author(s):  
Ashraf Moini ◽  
Shahin Tadayon ◽  
Afsaneh Tehranian ◽  
Ladan Mohammadi Yeganeh ◽  
Mohammad Reza Akhoond ◽  
...  
Keyword(s):  
Pregnancy Loss ◽  
Polycystic Ovarian Syndrome ◽  
Recurrent Pregnancy Loss ◽  
History Of ◽  
Ovarian Syndrome

scholarly journals Severe Adolescent Menorrhagia due to Cervical Fibroid

2010 ◽  
Vol 2 (1) ◽  
pp. 65-66
Author(s):  
Tejshree Singh ◽  
Abha Majumdar
Keyword(s):  
Sexual Activity ◽  
Rare Case ◽  
Polycystic Ovarian Syndrome ◽  
Pelvic Examination ◽  
Blood Tests ◽  
History Of ◽  
Local Examination ◽  
Secretory Endometrium ◽  
Ovarian Syndrome ◽  
Cervical Polyp

ABSTRACT A rare case of severe menorrhagia in a young girl with polycystic ovarian syndrome (PCOS) is presented. On thorough investigations (blood tests and ultrasound) nothing substantial came up, hence ultimately pelvic examination under anesthesia was undertaken, which uncovered a cervical polyp 2.5 × 2.5 × 1.5 cm size, with a intracervical broad base, presenting at the external os but not protruding into the vagina. The growth was electrocauterized at its base, resected and a thorough curettage was done. Histopathology revealed a myomatous polyp and secretory endometrium. Though always a dilemma, in adolescent menorrhagia, a pelvic examination may be lifesaving in certain cases, if diagnosis is unclear. The importance of doing a thorough local examination in spite of absent history of sexual activity is highlighted by the following case.

scholarly journals Polycystic ovarian syndrome: rs1799752 polymorphism of ACE gene

2018 ◽  
Vol 64 (11) ◽  
pp. 1017-1022
Author(s):  
Mariangela Torreglosa Ruiz Cintra ◽  
Marly Aparecida Spadotto Balarin ◽  
Sarah Cristina Sato Vaz Tanaka ◽  
Vanessa Iorrana Mota da Silva ◽  
Alessandra Bernadete Trovó de Marqui ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Descriptive Analysis ◽  
Univariate Analysis ◽  
Control Group ◽  
Genotypic Frequency ◽  
Significance Level ◽  
Ace Gene ◽  
History Of ◽  
Study Population ◽  
Ovarian Syndrome

SUMMARY PURPOSE: To investigate the contribution of the deletion polymorphism and insertion (rs1799752) of the angiotensin converting enzyme (ACE) gene in the aetiology of Polycystic Ovarian Syndrome (PCOS). METHODOLOGY: 97 women diagnosed with PCOS who received care at the Gynaecology and Obstetrics clinic of the Hospital das Clínicas of UFTM, participated in this study. The control group consisted of 94 women. All participants were submitted to the collection of 10 mL of whole blood and the genomic DNA was obtained by the saline extraction method. The genotyping of the samples was performed by means of the Polymerase Chain Reaction (PCR). The statistics analyses were performed by descriptive analysis, univariate analysis and logistic regression model. The results were presented in odds ratio (OR) and confidence interval of 95% (CI-95%), with a significance level of 5% (p≤0.05). RESULTS: There were no statistical differences between patients and controls for the genotypic (χ2 = 1.52, p = 0.47) and allelic frequencies (χ2 = 0.21, p = 0.76). The distribution of the genotypic frequency is not in HWE for patients (χ2 = 18.80, p <0.05) and for controls (χ2 = 6.85, p <0.05). In relation to the risk factors for the syndrome, the history of familial PCOS is more frequent between women with the syndrome. CONCLUSION: In the study population, there was no association between I/D polymorphism of the ACE gene and PCOS.

scholarly journals Polycystic ovarian syndrome among adolescent and young women: a hospital based observational study in a tertiary care teaching Hospital

2020 ◽  
Vol 9 (3) ◽  
pp. 1097
Author(s):  
Arpita Jain ◽  
Swati Garg ◽  
Urvashi Sharma
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Serum Insulin ◽  
Tertiary Care ◽  
Early Screening ◽  
Serum Lh ◽  
Epidemic Area ◽  
Pcos Group ◽  
History Of ◽  
Sugar Levels ◽  
Ovarian Syndrome

Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorder among women of fertile age. The incidence of PCOS as claimed by various observer ranges from 2.2% to as high as 26%. India is considered as an emerging epidemic area for PCOS and limited studies are done. Hence aim of this study is to find the prevalence of PCOS and determine the associated determining factors in adolescent girls.Methods: All the girls aged 15-24 years were approached and after undergoing detailed history, examination and investigations were further diagnosed as PCOS. The study subjects were then classified into two group: the PCOS and non-PCOS group and compared to determine significant differences as per the Rotterdam criteria.Results: The prevalence of PCOS was 7.5%, 18.68% and 11.18% as per NIH, Rotterdam and AES criteria respectively. BMI more than 30, waist circumference > 80 cm, hyperandrogenic manifestations, menstrual irregularity (oligomenorrhea) and family history of PCOS and DM showed statistically significant association with PCOS. Serum LH, LH/FSH ratio, S. Testosterones, serum insulin and HOMA-IR had significant association with PCOS. No significant association of Fasting blood sugar levels and deranged lipid profile was found with PCOS.Conclusions: PCOS is an emerging disorder during adolescents and hence awareness creation, early screening in order to inculcate early life style modifications and prevent metabolic and reproductive complications of this disease.

scholarly journals FREQUENCY OF GENERALIZED ANXIETY DISORDERS IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME

2021 ◽  
Vol 71 (4) ◽  
pp. 1455-59
Author(s):  
Rabia Asghar ◽  
Usama Bin Zubair ◽  
Syed Azhar Ali ◽  
Ayaz Muhammad Khan ◽  
Aneel Shafi ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Generalized Anxiety Disorder ◽  
Psychiatric Illness ◽  
Polycystic Ovarian Syndrome ◽  
Education Level ◽  
Generalized Anxiety ◽  
Generalized Anxiety Disorders ◽  
History Of ◽  
Ovarian Syndrome

Objective: To determine the factors associated with generalized anxiety disorders in patients presenting with polycystic ovarian syndrome. Study Design: Cross-sectional study. Place and Duration of Study: Gynecology and Psychiatric outpatient department of Pakistan Institute of Medical Sciences, SZABMU, Islamabad, from Jan to Jul 2016. Methodology: Patients presenting with polycystic ovarian syndrome were enrolled. Patients were selected from the gynaecological and Medicine department. Patient’s history was taken and diagnosis of generalized anxiety disorder was made utilising Generalized Anxiety Disorder-7. Patients having diabetes mellitus, hypertension, Cushing’s syndrome, hypoglycaemia, co-morbid psychiatric illnesses, history of psychiatric illness in past and family history of psychiatric illness were excluded from the study. Results: Among 105 patients with polycystic ovarian syndrome, 79 (75%) patients had no generalized anxiety disorders while, 26 (25%) had generalized anxiety disorders. 2 out of 12 (16.6%) patients of age range of 15-20 year had generalized anxiety disorders, 9 out of 63 14.2% patients having age 21-30 years had generalized anxiety disorders and 15 out of 30 (50%) patients having age 31-40 years age had generalized anxiety disorders. Chi-square test revealed age, education level and socioeconomic status has a significant association with presence of generalized anxiety disorder among patients of polycystic ovarian disorder (with p-value <0.05). Conclusion: Generalized anxiety disorder was common in patients with polycystic ovarian syndrome. Age, low education level and low socioeconomic status had a significant relationship with generalized anxiety disorder in polycystic ovarian syndrome patients.

Association Of Acne Vulgaris With Polycystic Ovarian Syndrome In Patients Visiting UOL Teaching Hospital

2021 ◽  
Vol 15 (6) ◽  
pp. 1299-1301
Author(s):  
A. Malik ◽  
S. A H. Kazmi
Keyword(s):  
Teaching Hospital ◽  
Polycystic Ovarian Syndrome ◽  
Acne Vulgaris ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Study Population ◽  
Ovarian Syndrome

Background: Polycystic syndrome (PCOS) is the most common endocrine disorder in the world affecting 8% of women. The main characters of PCOS are enlarged ovaries, chronic ovulation, menstrual cycles disturbance, androgen overdose, and insulin resistance leading to acne, hirsutism, and reproductive problems. Acne is a quite common dermatological condition in daily practice. Aim: To determine the association of acne vulgaris with polycystic ovarian syndrome in patients visiting the University of Lahore Teaching Hospital. Study design: Descriptive cross-sectional study. Place and duration of study: Dermatology Outpatient Department, University of Lahore Teaching Hospital Lahore from March 2019 to March 2020. Methodology: It was a descriptive cross-sectional study from March 2019 to March 2020 conducted at the Dermatology Out-patient Department, University of Lahore Teaching Hospital. All patients between the ages of 18 and 40, with acne vulgaris were included in the study. After obtaining informed consent, 101 women with acne vulgaris in I-IV (Indian stages), between the ages of 18-40 years, presented in the Department of Dermatology, University of Lahore Teaching Hospital, from March 2019 to March 2020, were selected for the study. Pregnant females, lactating mothers, and women on hormonal treatment (oral contraceptives or injections) were excluded from the study. A history of acne, oligomenorrhea, hirsutism, seborrhea, alopecia, acanthosis nigricans infertility, obesity and amenorrhea were taken. Weight and height were measured to calculate BMI. Data were collected in a special statistically tool and analyzed using SPSS-25. Results: A total of 101 women were examined having acne vulgaris issue. A total of 101 female were assessed and having history of acne vulgaris. Out of this, 33 were 18–23 years old, while 24 (23.4%) have ages 24–28 years. There were 18 (17.8%) patients who have 29–33 years old. while 38–40 years were 10 (9.9%) years old. Irregular menstrualcycle was reported 34.6% of the study population. As Perth WHO criteria, only 17% of the participants had BMI in normal weight range. The proportion of women, who were overweight and obese were 50.4% and 32.6% in the study population. Conclusion: Acne vulgaris has been identified as a serious skin disease found in all age groups. PCOS is more common among women with acne and obesity is a major risk factor for PCOS.

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