scholarly journals Features of distal lesion of the peripheral nerves in the upper extremities in vibration disease due to local vibration

2020 ◽  
Vol 99 (7) ◽  
pp. 699-703
Author(s):  
Anastasia V. Yamshchikova ◽  
Arnold N. Fleishman ◽  
Margarita O. Gidayatova ◽  
Alla A. Kungurova
Keyword(s):  
Peripheral Nerves ◽  
Prolonged Exposure ◽  
Main Group ◽  
Upper Extremities ◽  
Control Group ◽  
Local Vibration ◽  
Cross Sectional ◽  
Vibration Disease ◽  
Ultrasound Study ◽  
Functional Features

Introduction. The relevance of the study is dictated by the difficulties of differential diagnosis of neural lesions of the upper extremities in vibration disease induced by local vibration. The most frequent involvement of the distal nerves of the upper extremities can be due to both a polyneuropathic diffuse disturbance without compression and a compression tunnel lesion. Taken into account the different approaches to the treatment of these conditions, there is a need to study the features of distal nerve damage in the case of vibration damage.Aim of the study was to investigate the macrostructural and functional features of distal lesions of the peripheral nerves of the upper extremities in vibration disease patients.Material and methods. 57 men aged 40-60 years were examined at the clinic of the Research Institute for Complex Problems of Hygiene and Occupational Diseases in Novokuznetsk, 30 patients with a proven diagnosis of vibration disease were included in the main group, 27 cases who had never worked in contact with industrial vibration were included in the control group. An electroneuromyographic and ultrasound study of the median and ulnar nerve were performed in all cases.Results. A significant increase in the distal latency of the median nerves and a decrease in the speed of sensory conduction along the nerves of the upper extremities in the main group were revealed. According to the ultrasound examination of the nerves, there was no statistical difference in the nerve cross-sectional area at the level of the wrist in the main and control groups. The frequency of compression lesions of the median nerve in the carpal canal in the main group accounted for 16%.Conclusions. With prolonged exposure to local vibration, a distal polyneuropathic diffuse lesion of the nerves of the upper extremities often develops. A combination of vibration disease due to local vibration and carpal tunnel syndrome occurs in 16% of cases.

Antioxidant status of blood in patients with vibration disease

2019 ◽  
pp. 978-982 ◽  
Author(s):  
N. N. Malyutina ◽  
A. F. Bolotova ◽  
R. B. Eremeev ◽  
A. Zh. Gilmanov ◽  
D. Yu. Sosnin
Keyword(s):  
Antioxidant Activity ◽  
Blood Serum ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Main Group ◽  
Biologically Active ◽  
Antioxidant Systems ◽  
Control Group ◽  
Vibration Disease ◽  
Total Antioxidant

Introduction. The overwhelming number of publications contains only data on the content of individual antioxidants, but not on the overall antioxidant activity of the blood in patients with vibration disease.The aim of the study was to determine the total antioxidant activity of blood serum in patients with vibration disease.Materials and methods. Th e main group consisted of 30 people diagnosed with “Vibration disease” of 1 degree (n=21) and 2 degrees (n=9). Th e control group consisted of 30 clinically healthy men, comparable in age with the main group (p=0.66). Th e total activity of antioxidant systems of blood plasma was evaluated photometrically using the test system “Total antioxidant status-Novo” (“Vector-best”, Russia).Results. The indicator of the total antioxidant status (TAS) was 1,038±0.232 mmol/l in the examined main group, against 1,456±0.225 mmol/l in the examined control group (p<0.000001). Th e coefficient of variation (CV) in patients with vibration disease was 22.35%, 1.45 times higher than in the control group (15.45%). In the main group there was a positive correlation between age and TAS (R=0.525), in the control group there was no such relationship (R=0.095). Th e degree of decrease depended on the severity of vibration disease.Conclusions. 1. The development of vibration disease is accompanied by a decrease in the antioxidant status of blood serum. 2. Th e degree of decrease in the antioxidant status of blood serum correlates with the severity of vibration disease. 3. Reduction of TAS can serve as a pathogenetic justification of the need to include drugs and/or biologically active additives with antioxidant activity in therapy

Formation of pathology of internal organs in miners with vibration disease

2020 ◽  
pp. 399-403
Author(s):  
O. Yu. Korotenko ◽  
N. I. Panev ◽  
Yu. S. Korchagina ◽  
R. N. Panev ◽  
I. P. Danilov
Keyword(s):  
Cardiovascular System ◽  
Kidney Diseases ◽  
Coal Industry ◽  
Control Group ◽  
Internal Organs ◽  
Local Vibration ◽  
Vibration Disease ◽  
Long Time ◽  
Somatic Diseases ◽  
Medical Examinations

Introduction. Adverse working conditions can contribute to the development of not only occupational pathology, but also diseases with complex multifactorial etiology, such as hypertension, coronary heart disease, disorders of the musculoskeletal system, chronic non-specifi c respiratory diseases, as well as the formation of combined pathology, which worsens the course of these diseases and leads to the development of complications.The aim of the study is to study the manifestations of somatic pathology in coal industry workers with vibration disease.Materials and methods. We examined 144 coal mine workers with vibration disease caused by local vibration, and 161 control group miners who have been working in contact with local vibration for a long time (15 years or more) and do not have professional pathology.It was found that employees of coal mines with vibration disease more often (70,8%) than workers of the control group (27,3%) (p<0,001), there is a pathology of internal organs: diseases of the cardiovascular system (mainly arterial hypertension), diseases of the digestive system (functional disorders of the biliary tract and non-alcoholic fatt y liver disease), kidney diseases (mainly chronic pyelonephritis), as well as a combination of these diseases. With a more severe course of vibration disease (II degree), pathology of internal organs is more common (81.2%) than in patients with vibration disease of I degree (46.5%) (p<0.001). Conclusions. In miners with vibration disease, more oft en than in the control group, there is a pathology of internal organs: the cardiovascular system, digestive organs, kidneys, as well as a combination of several somatic diseases. In individuals with grade II vibration disease, internal organ pathology is more common than in patients with grade I vibration disease. Th e results obtained should be considered when developing treatment and rehabilitation measures for medical examinations and conducting preventive medical examinations of coal industry workers. 

Postural disorders in patients with vibration disease

2019 ◽  
pp. 314-318
Author(s):  
Larisa S. Vasileva ◽  
Natalya V. Slivnitsyna ◽  
Oleg L. Lakhman
Keyword(s):  
Center Of Pressure ◽  
Statistical Significance ◽  
Statistical Processing ◽  
Control Group ◽  
Combined Effects ◽  
Local Vibration ◽  
Vibration Disease ◽  
Eyes Closed ◽  
Significant Difference ◽  
Postural Disorders

Introduction. Vibration disease (VD) is one of the leading occupational diseases. One of the manifestations of this disease when exposed to general vibration may be a violation of balance.The aim of the study is to identify the imbalance and the causes of their occurrence in patients with vibration disease.Materials and methods. 3 groups of patients were examined. The first group consisted of 50 patients diagnosed with VD associated with combined exposure to local and general vibration (age 48.7±3.1 years); the second group consisted of 50 patients diagnosed with VD associated with exposure to local vibration (age 48.9+2.8 years); the control group consisted of 50 relatively healthy men not in contact with vibration (age 49.1+2.5 years). Survey on electronic stabilometer ST–150 (Biomera, Russia). Patients performed the Romberg test standing barefoot vertically on a stabilometric platform with a “European” stop position. Statistical processing of the results was carried out using the software package “Statistica 10.0” (StatSof, USA, 2011). Methods of descriptive statistics included estimation of median, lower and upper quartiles. The statistical significance of the differences was determined using the nonparametric Wilkinson method. Differences were considered statistically significant at p<0.05.Results. In the analysis of the obtained stabilometric parameters found that in the first group of patients marked imbalance.Moreover, in comparison with the second group and the control group in the phase with eyes closed, patients are more difficult to maintain a given posture, which increases the length of statokinesigram (p=0.02 and p=0.005), increasing the speed of movement of the center of pressure (p=0.03 and p=0.004) and the square of the deviation of the center of pressure (p=0.03 and p=0.004). When closing the eyes, patients put more effort to maintain balance, which affects the rate of mechanical work (p=0.001 and p=0.001). When comparing the second group with the control group, no statistically significant difference was found in the main stabilometric indicators.Conclusions: In the group of patients with VD associated with the combined effects of local and general vibration, marked (64%) and moderate (36%) postural disorders, especially in the phase of closed eyes. In the group of patients with VS associated with local vibration exposure and in the control group, imbalance was detected in 10% and 6%, respectively. The leading role in the occurrence of postural disorders in patients with VD, associated with the combined effects of local and general vibration, plays the formation of a focus of stagnant excitation in the centers of vibration sensitivity. In the future, the pulse can spread to nearby centers of pain, temperature sensitivity and proprioception, which contributes to the emergence of lower limb polyneuropathy and impaired stability in patients with vibration disease.

Vibration disease: erectile dysfunction as a comorbidity problem

2020 ◽  
pp. 36-43
Author(s):  
S. Babanov ◽  
N. Tatarovskay
Keyword(s):  
Erectile Dysfunction ◽  
Questionnaire Survey ◽  
Erectile Function ◽  
Control Group ◽  
Local Vibration ◽  
Vibration Disease ◽  
Male Patients ◽  
And Control ◽  
The Impact ◽  
Second Degree

The article presents data (based on a questionnaire survey) on the impact of vibration disease from the action of local and General vibration on the erectile function of men. The main changes in the parameters of erectile function (frequency, need, etc.) are described in the case of first and second-degree vibrational disease caused by local vibration, and in the case of first-and second-degree vibrational disease caused by General vibration based on data from a questionnaire survey of male patients and control group.

scholarly journals CHARACTERISTICS OF DISTURBANCES IN NEUROPHYSIOLOGICAL AND PSYCHO-EMOTIONAL STATUS OF PATIENTS WITH VIBRATION DISEASE IN THE POSTEXPOSURE PERIOD

2016 ◽  
Vol 1 (6) ◽  
pp. 98-102
Author(s):  
Лахман ◽  
Oleg Lakhman ◽  
Катаманова ◽  
Elena Katamanova ◽  
Кулешова ◽  
...  
Keyword(s):  
Exposure Period ◽  
Control Group ◽  
Bioelectrical Activity ◽  
Length Of Service ◽  
Local Vibration ◽  
Afferent Pathways ◽  
Post Exposure ◽  
Vibration Disease ◽  
Upper And Lower Extremities ◽  
The Mean

The article presents the results of the studies of the central and peripheral nervous systems, psychoemotional status of patients with vibration disease associated with exposure to the local vibration in the post-exposure period. The stud-ies were performed in patients with vibration disease (n=18) who do not work in the contact with the local vibration at present. The mean age of the patients was 50.7±5.4years, the mean length of service in the contact with local vibration –17.9±2.8years, the mean post-exposure period – 5.2±2.2years. 30male persons having no contact with industrial hazard were comprised the control group. Electroencephalography, electroneuromyography, recording of somatosensory evoked potentials were carried out and patients’ personality peculiarities were studied. The changes of the brain bioelectrical activity, disorders of the autonomic and afferent regulation of the cerebral level, dysfunc-tion in diencephalic structures, disorders of the subcortical and cortical structures of the central afferent pathways; demyelization of the peripheral nerves of the upper and lower extremities were set in patients with vibration disease in the post-exposure period. Psychological studies have shown that patients with vibration disease in the post-exposure period preserve such psychological peculiarities as neuroticism manifested with inner tension, nervousness and chronic feeling of discomfort; depressive tendencies being a sign of the existing distress, and anxious-hypochondriac features in the structure of personality traits. All of the above result in formation of stable uncompensated clinical conditions observed in patients with vibration disease caused by local vibration exposure, even after the termination of harmful production factors.

scholarly journals AB0667 ACHILLES PAIN PERSISTENCE IN PATIENTS AFFECTED BY SPONDYLOARTHRITIS: ULTRASONOGRAPHIC AND BIOMECHANICAL STUDY.

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1628.2-1629
Author(s):  
A. Batticciotto ◽  
S. Olivieri ◽  
R. Talotta ◽  
A. Cappelli ◽  
A. Preda ◽  
...  
Keyword(s):  
Functional Disability ◽  
Power Doppler ◽  
Biomechanical Study ◽  
Ankle Dorsiflexion ◽  
Control Group ◽  
Cross Sectional ◽  
Ultrasound Study ◽  
Number Of Patients ◽  
Biomechanical Evaluation ◽  
The Mean

Background:Enthesis anatomy and biomechanics have a key role in Spondyloarthritis (SpA) pathogenesis (1) but few data are available about the influence of structural and biomechanical changes of Achilles tendon (AT) on persisting pain in longstanding SpA patients.Objectives:To correlate AT pain in longstanding SpA patients with ultrasonographic detectable disorders and biomechanical abnormalities.Methods:We performed a monocentric cross-sectional analysis including 35 consecutive patients affected by SpA (13 with Psoriatic Arthritis, 9 with Enteropathic SpA, 6 with Ankylosing Spondylitis and 7 with Undifferentiated SpA) under treatment with anti- TNF agents. A rheumatologic clinical and clinimetric evaluation (AT VAS pain, BASDAI, BASFI, HAQ), an ultrasound study of AT according to the Madrid Sonographic Enthesis Index (MASEI) score and a podiatrist biomechanical evaluation [Foot posture index (FPI), degree of ankle dorsiflexion with the knee extended and flexed] were performed.Results:Study population (13 F; 22 M; mean age 54.9 ±13.9 years; mean disease duration 9.5 ± 5.0 years; mean BMI 25.8 ±4.4) showed a mean AT VAS pain of 3.4 ± 2.2, a mean HAQ of 0.6 ± 0.6, a mean BASDAI of 3.3 ±2.1 and a mean BASFI of 2.2 ±1.9. At the ultrasonographic evaluation 47% (33/70) of the AT entheses analysed presented a dishomogeneous echostructure, 31% (22/70) structural thickness, 53% (37/70) calcifications, 10% (7/70) erosions, 44% (31/70) a retrocalcanear bursitis. A power Doppler positivity was found only in 0.07% (5/70) of the AT.At the biomechanical evaluation 50% (35/70) of the feet showed a FPI score between 0 and + 5 (neutral foot), 46% (32/70) a FPI score between +6 and +9 (slight foot pronation) and 6% (4/70) a FPI score between -1 and -4 (slight foot supination).The mean degree of ankle dorsiflexion with extended knee was 8.4 ± 3.9 with the 61% (43/70) of the patients with a maximum dorsiflexion < 10° of whom 46% (20/43) do not recover after the knee flexion.We found a between the mean degree of left ankle dorsiflexion with extended/flexed knee both with ultrasound-revealed left AT enthesis calcifications (p=0.014/0.037) and with left AT enthesis thickness (p=0.049/0.035), and a significant association between the mean degree of right ankle dorsiflexion and extended/flexed knee and ultrasound-revealed right AT calcifications (p=0.008/0.012). Moreover, we noticed an inverse correlation between the mean overall degree of ankle dorsiflexion with extended/flexed knee and the BASFI values (p=0.007/0.004). AT VAS pain was statistically related with Achilles PDUS signal persistence (p=0.048) but not with US signs of chronic entesopathy or biomechanical alterations [calcification (p=0.39), erosions (p=0.74)]. The limits of the study were the low number of patients recruited and the lack of a control group.Conclusion:In this monocentric study on a cohort of SpA patients, we demonstrated a statistically significant correlation between ankle–subtalar joint complex biomechanics alterations, ultrasonographic signs of chronic enthesopathy and clinimetric index of functional disability. Residual Achilles pain seems to be related to US signs of active enthesitis.References:[1]The enthesis organ concept and its relevance to the spondyloarthropathies. Benjamin, M and McGonagle, D. s.l.: Adv Exp Med Biol, 2009, Vol. 649.[2]The Synovio-entheseal Complex and Its Role in Tendon and Capsular Associated Inflammation. McGonagle, E D, Aydin, SZ and Tan, AL. 0, s.l.: J Rheumatol Suppl, 2012, Vol. 89Disclosure of Interests:None declared

scholarly journals The Possibility of Correcting Anxiety Symptoms in Cardiac Patients in Primary Care Settings: Results of the Therapeutic Part of a Russian Multicenter Study COMETA

Kardiologiia ◽  
2019 ◽  
Vol 59 (9) ◽  
pp. 29-39
Author(s):  
N. V. Pogosova ◽  
Y. M. Yufereva ◽  
A. K. Ausheva ◽  
A. A. Kursakov ◽  
A. A. Arutyunov ◽  
...  
Keyword(s):  
Depression Scale ◽  
Main Group ◽  
Anxiety Symptoms ◽  
Psychological Status ◽  
Control Group ◽  
Anxiety State ◽  
Control Groups ◽  
Cross Sectional ◽  
Psychoemotional Stress ◽  
And Control

Purpose: to assess efficacy of correction of anxiety states by anxiolytic drug fabomotizole in ambulatory patients with arterial hypertension (AH) and / or ischemic heart disease (IHD).Materials and methods. In the framework of multicenter cross-sectional study with participation of patients aged ≥55 years with verified AH / IHD we conducted the therapeutic part of the COMETA program in which we included patients with comorbid anxiety state (≥11 points on the Hospital Anxiety and Depression Scale Anxiety [HADS-A] and clinically expressed anxiety state) without clinically expressed depressive symptoms (<11 points on the HADS-Depression). Participants were randomized into main and control groups. Patients in the main group in addition to therapy prescribed because of AH / IHD were given a recommendation to take fabomotizole (10 mg thrice a day), patients of control group received standard therapy. Efficacy of therapy was evaluated by HADS and visual analog scale after 6 and 12 weeks of observation.Results. We included 182 and 104 in the main and control groups, respectively. Most patients in main and control groups had AH (97.3 and 95.2 %, respectively, about one third had IHD (36.8 and 30.8 %, respectively). Social-demographic, clinical characteristics, and recommended for AH / IHD treatment of participants of both groups were similar. Portion of patients with complete reduction of anxiety symptoms (<8 points on HADS-A) was significantly higher already after 6 weeks of fabomotizole therapy (37.9 and 19.2 %, respectively, p<0.001). Analogous picture was noted by the end of observation (66.9 and 32 %, respectively; p<0.001). Mean estimate of chronic psychoemotional stress in the main group decreased by 25 % after 6 weeks (from 6.45±2.20 to 5.05±1.96 points; р<0.001) and by 40 % after 12 weeks (from 6.45±2.20 to 3.98±1.99 points; р<0.001). In the control group it also decreased but degree of lowering was 2 times less than in the main group (11.1 % vs. 25 % after 6 weeks, р=0.016; and 20 % vs. 40 % after 12 weeks, р<0.001, respectively).Conclusion. The use of fabomotizole by patients with AH / IHD provided improvement of psychological status (reduction of anxiety symptoms and lowering of the level of chronic psychoemotional stress).

scholarly journals MALE REPRODUCTIVE FUNCTION IN CONCURRENT VIBRATION DISEASE AND ARTERIAL HYPERTENSION

2019 ◽  
Vol 4 (1) ◽  
pp. 32-36
Author(s):  
Sergey A. Babanov ◽  
Rimma A. Baraeva
Keyword(s):  
Erectile Dysfunction ◽  
Arterial Hypertension ◽  
Erectile Function ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Control Group ◽  
Androgen Deficiency ◽  
Local Vibration ◽  
Body Vibration ◽  
Vibration Disease

Objectives - to study the severity of androgen deficiency and erectile dysfunction in patients with vibration disease and in its combination with arterial hypertension. Material and methods. 145 male patients with various forms of vibration disease were thoroughly examined. The following groups were defined - I stage and II stage vibration disease induced by local vibration; II stage, induced by local vibration with concurrent arterial hypertension; I and II stage vibration disease induced by whole body vibration; II stage vibration disease induced by whole body vibration with concurrent arterial hypertension. The control group included 30 patients. Evaluation of erectile function in men with vibration disease and its combination with arterial hypertension was carried out using the scale of severity of erectile dysfunction (International Index of Erectile Function, IIEF-5). The questionnaire for detection of androgen deficiency (Dedov II, Kalinchenko SYu, 2006) and the AMS (aging males' symptoms) questionnaire assisted in revealing the symptoms of aging in men. Results. According to the IIEF-5 questionnaire results the erectile dysfunction was defined in patients with vibration disease, most pronounced in II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension. AMS-questionnaire presented the most expressed signs of androgen deficiency in patients with II stage of vibration disease induced by whole body vibration and in vibration disease of any etiology with concurrent arterial hypertension (p

scholarly journals THE STATE OF THE CENTRAL AND PERIPHERAL CONDUCTIVE STRUCTURES IN PATIENTS WITH VIBRATION DISEASE

2019 ◽  
Vol 98 (10) ◽  
pp. 1085-1090
Author(s):  
Dina V. Rusanova ◽  
O. L. Lakhman
Keyword(s):  
Peripheral Nerves ◽  
Lower Extremities ◽  
The State ◽  
Combined Effect ◽  
Control Group ◽  
Thalamic Nuclei ◽  
Afferent Pathways ◽  
Professional Activities ◽  
Vibration Disease ◽  
Group 1

Introduction. The defeat of motor and sensory conductive structures, which ultimately leads to the development of demyelination processes and, as a consequence, the formation of polyneuropathic syndrome is natural under the influence of industrial vibrations. Exposure to vibration, along with other harmful working conditions, can potentiate the development of metabolic syndrome, which can lead to the development of diabetes, which is one of the most common causes of damage to the peripheral nervous system. Based on the above, it seems relevant to give a comprehensive assessment of the state of peripheral nerves and afferent conductive structures in workers exposed in their professional activities combined effect of local and general vibration, and patients with vibration disease, burdened with diabetes. Material and methods. 114 people were examined in clinical conditions. The observed cases included 50 with vibration disease (WB) associated with exposure to local and General vibration (group 1), the second group - 29 people with WB, burdened with type 2 diabetes. The control group (group 3) consisted of 35 conditionally healthy men, representative age (52.0±6.4 years) without contact with harmful factors of production. Results. In patients of group 1, changes were observed in increasing the time of postsynaptic activation of the posterior horns of the spinal cord and activation of neurons of the somatosensory zone of the cerebral cortex. In patients of group 2, changes in the state of the central afferent pathways were more pronounced, shown in increasing the time of the excitation wave from the cervical thickening to the thalamic nuclei, as well as violations in the state of the conductive structures in the thalamic region. Analysis of the peripheral nerves in group 1 patients revealed changes in demyelinating lesions of the motor and sensory components of the tibial nerve and changes in the speed indices of the nerves of the upper extremities. The examined 2 groups had similar disorders, there was a statistically significant decrease in the speed of sensory axons of the lower extremities. conclusion. It was found that the combined effect of vibration and diabetes mellitus leads to aggravation of the demyelination processes of both sensory and motor axons of peripheral nerves in patients. There is a statistically significant decrease in the amplitude of the M-response on the lower extremities.

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