scholarly journals The relationship of polymorphic variants of genes GSTM1, GSTT1, GSTP1 with the risk of developing diseases (literature review)

2021 ◽  
Vol 100 (12) ◽  
pp. 1385-1390
Author(s):  
A. M. Amromina ◽  
I. A. Sitnikov ◽  
D. R. Shaikhova
Keyword(s):  
Russian Federation ◽  
Gene Polymorphisms ◽  
Glutathione Transferase ◽  
Glutathione S Transferase ◽  
Scientific Publications ◽  
Scientific Papers ◽  
Oncological Diseases ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship

Authors analyzed the relationship of the most studied polymorphisms of glutathione-S-transferase genes (GSTT1, GSTM1, GSTP1) with the risk of developing diseases in the territory of the Russian Federation. The authors analyzed domestic articles on gene polymorphisms and their association with various conditions. A systematic review of scientific papers was carried out using the following electronic databases: Cyberleninka, Electronic Library and Google Scholar, which searched for glutathione transferase (GST) gene polymorphisms from 1900 to 2020. The following keywords were used for the search: “GST polymorphism”. The search for articles was carried out in English but took into account the results obtained only in the territory of the Russian Federation. The search for scientific publications was independently checked and compared to filter out duplicate articles. The sample size, the number of loci included in the analysis, and the analyzed population (ethnic group) are essential in studying the relationship between glutathione S-transferase gene polymorphisms and the development of diseases. In general, the analysis of the articles makes it possible to reveal the association between the polymorphisms of the glutathione-S-transferase genes and the high risk of developing oncological diseases, respiratory diseases and other pathologies. This article did not consider the relationship of polymorphisms with reproductive pathologies because this topic includes a large amount of work and requires separate consideration. The least studied issue is the relationship between polymorphisms of genes for biotransformation of xenobiotics and the development of occupational diseases.

SECTANITY IN THE CONTEXT OF MANIFESTATIONS OF MODERN RELIGIOUS EXTREMISM

2020 ◽  
Author(s):  
Pavel Agapov ◽  
Kirill Stepkin
Keyword(s):  
Russian Federation ◽  
Religious Extremism ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship ◽  
Theoretical Foundations

The article considers the general theoretical foundations of the relationship of sectarianism and religious extremism in the Russian Federation. Practical examples of the role of destructive sects in modern religious extremism in the Russian Federation are given.

scholarly journals Method of Calculating the Integral Indicator for Assessing Threats to the Economic Security of the Russian Federation

2020 ◽  
pp. 56-63
Author(s):  
Alexander Vladimirovich Prokopyev
Keyword(s):  
Russian Federation ◽  
National Economy ◽  
Economic Security ◽  
Security Threats ◽  
Legal Documents ◽  
Significance Levels ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship ◽  
Integral Indicator

The paper analyzes and systematizes the basic catego-ries related with threats to the economic security of the Russian Federation, and establishes the relationship of their components in accordance with Federal regulatory legal documents. It provides an overview of the ap-proaches contained in the works of different authors in relation to the formation of the composition of threats to the economic security of the state and the assess-ment of their relevance. As a result, it is concluded that it is necessary to improve existing methods for as-sessing economic security threats for the national economy. The author’s method of calculating an inte-gral indicator for assessing threats to the economic security of the Russian Federation, based on a system of indicators grouped into clusters, is proposed. The initial approbation of the methodology was carried out on the basis of the author’s estimates of threshold val-ues and significance levels of indicators of economic security threats.

scholarly journals State Digitalzation Policy as a Factor of Sustainable Inclusive Growth and Development of Russian Regions

2020 ◽  
Vol 208 ◽  
pp. 08031
Author(s):  
Rustam Sharafutdinov ◽  
Vladislav Gerasimov ◽  
Elvir Akhmetshin ◽  
Hilary Okagbue ◽  
Asiyat Tagibova
Keyword(s):  
Russian Federation ◽  
Growth And Development ◽  
Population Based ◽  
Steady Increase ◽  
Inclusive Growth ◽  
The Social ◽  
Security Infrastructure ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship

This research paper addresses the need for digitalization of the economy in socially important areas of the Russian Federation, particularly its regions. The purpose of the study is to examine the relationship of digitalization with the processes of inclusive growth and regional development. The study identifies the main directions of the digitalization policy, its overall effectiveness, as well as those processes that make certain public goods more accessible for the population, namely: education, healthcare, security, infrastructure and their possible impact on inequality and the level of income of the population. Problems are identified in the existing national and regional digitalization policy, which is not able to ensure a steady increase in citizens’ incomes, high-quality and affordable higher education, as well as reduce the social tension of the population. Based on the foregoing, the authors offer recommendations for resolving these problems in terms of a digitalization approach and an improved digitalization policy with a view to sustainable inclusive socio-economic growth and development of the Russian Federation regions.

scholarly journals A review of the memoirs of the Governor of the Samara region Konstantin Alekseevich Titov in the journal Samara Destinies. Samara, 2019, no. 9

2021 ◽  
Vol 27 (4) ◽  
pp. 190-193
Author(s):  
S. N. Abrashkin
Keyword(s):  
Russian Federation ◽  
Personal Characteristics ◽  
Political Elite ◽  
The Political ◽  
Modern History ◽  
Political Career ◽  
History Of ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship

The review analyzes the memoirs of the first governor of the Samara region in the modern history of Russia Konstantin Alekseevich Titov. The ex-governor recorded the most important events of his political career, presented the personal characteristics of statesmen of the period of the 1990-s and early 2000-s. As a result of the study, it was found that in the memoirs of K.A.Titov, the relationship of the Samara governor with statesmen and representatives of the political elite of the Russian Federation is presented and fragmented his activities as a regional head of one of the largest regions of the Russian Federation.

scholarly journals ON FORECASTING THE INSURANCE MARKET IN RUSSIA AND IN THE ASTRAKHAN REGION

2018 ◽  
pp. 125-132
Author(s):  
Tatyana Vladimirovna Kotova ◽  
Ekaterina Vladimirovna Sokolova ◽  
Elena Vladimirovna Chernikina
Keyword(s):  
Russian Federation ◽  
Insurance Market ◽  
Insurance Companies ◽  
Positive Tendency ◽  
The Russian Federation ◽  
License Revocation ◽  
Relationship Of ◽  
High Degree ◽  
The Given ◽  
The Relationship

Insurance companies, being one of the most important links in the financial system of the country, make a significant contribution to the development of the national economy. Insufficient stability and a low level of dynamics of insurance development are conditioned by poor capitalization of insurance companies and absence of methodological complex, which would allow to create financial strategy with high degree of efficiency. In the Russian Federation today there are 236 insurance companies, of them 61 are in the Astrakhan region. Every year insurance companies cease their activity due to the license revocation. The study of the insurance market of the Astrakhan region and Russia using modern methods of scientific research, including mathematical models, made it possible to establish the relationship of insurance indicators with GDP and GRP. Studying the developing insurance market allowed to infer about the expediency of using the indicator “depth of the insurance market”. The forecast of this indicator until 2020 was based on the consensus forecast of the Ministry of Economic Development of the Russian Federation. Development of the insurance market and, consequently, the economy of the region and of the country is affected by many factors. The following indicators were considered as factors: dollar rate, price per gram of gold, MICEX index, central rate of the Central Bank of Russia, and the inflation rate. The constructed multifactorial regression model helped to establish the relationship between the volume of insurance premiums of voluntary insurance, the dollar exchange rate and the level of inflation. The given research algorithm can be used in various fields. The worked out forecast of the parameter of depth of insurance market in the Astrakhan region and Russia proved positive tendency in developing regional and Russian insurance market.

scholarly journals Category “measure” in the theory of penal law

2021 ◽  
Vol 1 (11) ◽  
pp. 28-31
Author(s):  
V.K. BAKULIN ◽  
Keyword(s):  
Russian Federation ◽  
Legal Obligation ◽  
Procedural Law ◽  
Procedure Code ◽  
Penal Law ◽  
The Subject ◽  
The Russian Federation ◽  
Definition Of ◽  
Relationship Of ◽  
The Relationship

The article analyzes the philosophical category “measure”, which due to its universality and comprehensiveness finds expression in law, since subjective law and legal obligation are always a measure of the possible or necessary behavior of the subjects of legal relations. The relationship of the category “measure” with the institutions of criminal and criminal procedural law is shown. The article examines the demonstrations of this category in the institutions of the penal law, which makes it possible to formulate the definition of a measure in the penal law and systematize the existing ones. There is revealed the need to change the subject of the penal law as a branch of law in connection with the empowerment of criminal executive inspectorates with the authority to implement measures of procedural coercion, provided for by the Criminal Procedure Code of the Russian Federation.

Problem of the Relationship of the Developed Oncological Disease with Radiation in Conditions of Production

2021 ◽  
Vol 65 (6) ◽  
pp. 76-82
Author(s):  
I. Galstyan ◽  
V. Nugis ◽  
F. Torubarov ◽  
B. Kukhta ◽  
M. Konchalovsky ◽  
...  
Keyword(s):  
Russian Federation ◽  
Oncological Disease ◽  
Foreign Countries ◽  
Radiation Induced ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship

Introduction. Compensation programs for radiation-induced diseases in some foreign countries. The data presented in UN documents. The linkage between irradiation and certain diseases in the Russian Federation. Conclusion.

scholarly journals Interaction with stakeholders as a factor in increasing the competitiveness of trans-Eurasian container rail freight transportation along transport corridors from the Far East to the western border of the Russian Federation: results of an empirical study

2020 ◽  
Vol 14 (79) ◽  
pp. 89-105
Author(s):  
N. V. Linder ◽  
◽  
M. O. Kuznetsova ◽  
Keyword(s):  
Russian Federation ◽  
Far East ◽  
The Far East ◽  
Western Border ◽  
Strategic Goals ◽  
The Russian Federation ◽  
Cargo Transportation ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

The article examines the relationship of stakeholders associated with trans-Eurasian railway containerized cargo transportation along transport corridors from the Far East to the western border of the Russian Federation (hereinafter RW CT). A stakeholder map has been generated, which allows us to identify the degree of influence of stakeholders on the achievement of strategic goals, as well as the impact of activities on the implementation of RW CT on stakeholders. Using the method of analyzing hierarchies, a hierarchy of stakeholders was established according to their importance in terms of achieving strategic goals (in particular, increasing the competitiveness of RW CT). Also, a hierarchy of goals and interests of stakeholders is defined to achieve strategic goals.

THE RELATIONSHIP OF THE ANTIBACTERIAL ACTIVITY OF A PLANT SPECIES WITH CHEMICAL COMPOUNDS OF DIFFERENT GROUPS: A STATISTICAL APPROACH

2021 ◽  
pp. 28-36
Author(s):  
Popov P.L.
Keyword(s):  
Russian Federation ◽  
Statistical Approach ◽  
Chemical Compounds ◽  
Statistical Criterion ◽  
Antibacterial Compound ◽  
The Russian Federation ◽  
Statistical Relationships ◽  
Relationship Of ◽  
The Relationship ◽  
Occurrence Of Species

The article deals with the question of the statistical attraction of chemical compounds that have an antibacterial effect and belong to various groups (terpenoids, phenols, flavonoids, quinones, alkaloids, lactones, coumarins, iridoids, xanthones) to the same types of plants. To assess the occurrence of species containing an antibacterial compound of a certain group in a set of species containing an antibacterial compound of another group (in comparison with the species of the flora of the Russian Federation outside this set), the student’s mathematical and statistical criterion was used. It is shown that in 12 combinations of groups ("terpenoids-phenols", "terpenoids-flavonoids", "terpenoids-quinones", "terpenoids-coumarins", "phenols-flavonoids". "Phenols-quinones", "phenols-coumarins", "flavonoids-coumarins", "flavonoids-iridoids", "flavonoids-xanthones", "lactones-coumarins") the occurrence of species containing an antibacterial compound related to one element of the combination is significantly increased in the set of species containing an antibacterial compound related to another element. It is noted that these statistical relationships are created by species belonging to 19 families of the flora of the Russian Federation (Iridaceae, Ranunculaceae, Chenopodyaceae, Ericaceae, Pyrolaceae, Salicaceae, Brassicaceae, Moraceae, Crassulaceae, Rosaceae, Fabaceae, Apiaceae, Valerianaceae,Viburnaceae,Rubiacae,Gentianaceae, Scrophulariaceae, Lamiaceae, Asteracaeae).

Ensuring the accelerated implementation of achievements of selection and seed-producing of potatoes in the conditions of market economy

2019 ◽  
pp. 59-65
Author(s):  
Vladimir Tulcheev ◽  
Roman Nekrasov ◽  
Sergey Zhevora ◽  
Elena Oves ◽  
Natalia Gordienko
Keyword(s):  
Market Economy ◽  
Seed Production ◽  
Russian Federation ◽  
Necessary Condition ◽  
Industrial Complex ◽  
The Russian Federation ◽  
Relationship Of ◽  
The Relationship ◽  
Seed Growing

The article provides a brief overview of the accelerated implementation of the achievements of selection and seed production in a developing market economy. The authors describe the main possible constraints to the spread of the achievements of Russian breeding and seed production using the example of the potato-food subcomplex. Thus, the authors believe that in the new competitive market conditions, the role of breeding, seed growing and accelerating innovation in the potato-food subcomplex of the agro-industrial complex of the Russian Federation is increasing, including the relationship of originators of varieties, seed-growing farms with other horizontal and vertical integrated potato-growing units, export and other structures. Resolution of contradictions between these parties is a necessary condition for successfully overcoming difficulties in the development of domestic selection and seed production.

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