scholarly journals A comparative clinical study of Khanda Shunthi and Prasarni Avaleha in the Management of Ama Vata w.s.r. to Rheumatoid Arthritis

2021 ◽  
Vol 12 (4) ◽  
pp. 954-960
Author(s):  
Anu Gupta ◽  
Chinky Goyal ◽  
Amitabh Singh
Keyword(s):  
Rheumatoid Arthritis ◽  
Joint Disease ◽  
Parallel Group ◽  
Pathogenic Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Lukewarm Water

Rheumatoid Arthritis is a chronic inflammatory joint disease characterized by swollen, painful and stiff joints. Amavata is a disease of Madhyama Roga Marga as it affects Sandhis and Haridaya Marma. Though Ama and Vata are the predominant pathogenic factors but the disease represents Tridoshic vitiation. The affliction of Sandhis by Vata dosha in association with Ama reflects the equal role of both Dosha and Dushya in the causation of disease. Moreover, the chief pathogenic factors, being contradictory in nature possess difficulty in planning the line of treatment. The objectives of this randomized parallel group comparative study were to evaluate the effect of Khanda Shunthi and Prasarni Avaleha in the management of Amavata. This Study was conducted on 40 patients selected randomly from OPD and IPD of Desh Bhagat Ayurvedic Hospital and divided into 2 trial groups A and B having 20 patients in each group. Group A received Khanda Shunthi 10 gms BD and Group B received Prasarni Avaleha 10 gms BD with lukewarm water for 60 days. Results showed statistically significant difference in effect of Group A and Group B on, Pain, Swelling, Stiffness, ESR, Walking time and Grip Strength except on Fever and HB. Percent wise Khanda Shunthi is found to be more effective than Prasarni Avaleha for all assessment criteria in the management of Amavata.

Comparative Clinical study of Jatyadi Taila and Jatyadi Ghrita in the management of Dushta Vrana

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar
Keyword(s):  
Clinical Study ◽  
Burning Sensation ◽  
Normal Process ◽  
Surgical Practice ◽  
Local Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Contaminated Wound ◽  
Group B

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

scholarly journals Role of Prophylactic Antibiotics in the Management of Postoperative Endodontic Pain

2015 ◽  
Vol 16 (12) ◽  
pp. 939-943 ◽  
Author(s):  
Leena Alsomadi ◽  
Riyad Al Habahbeh
Keyword(s):  
Pain Scale ◽  
Prophylactic Antibiotics ◽  
Post Treatment ◽  
Endodontic Treatment ◽  
Significant Difference ◽  
Group A ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Group B

ABSTRACT Aim To investigate the efficacy of using antibiotics in post endodontic treatment as a method to alleviate post-treatment pain. Materials and methods After completion of endodontic treatment 129 patients were randomly divided into two groups: Group A (65 patients) received Ibuprofen 400 mg one tablet before procedure and one tablet every 8 hours for the first day, then one tablet once indicated by pain. Group B (64 patients) received the same regimen as group A in addition to amoxicillin, clavulanic acid tablets (one tablet before the procedure, and then one tablet twice daily for a total of 3 days). Intensity of pain at 8 hours interval using visual analog scale (VAS) and total number of Ibuprofen tablets used was recorded by patients. Results Peak postoperative pain occurred at 16 hours posttreatment in both groups, there was a significant difference in the pain scale between the two groups in favor for group B over group A (3.8 vs 2.1 respectively). Pain scale was significantly lower in group B at 24, 32, 40, and 48 hours post-treatment with a p-value of < 0.05. The pain scale at 56, 64 and 72 hours were also less in group B, although could not show up as statistical difference. Patients in group A used statistically significant more Ibuprofen than patients in group B (486 vs 402). Conclusion Antibiotic prescription to manage post endodontic treatment pain results in less pain with less consumption of Ibuprofens. Clinical significance Pain management in endodontics is a real challenge, nonsteroidal anti-inflammatory drugs (NSAIDS) are used effectively in many patients to alleviate post endodontic pain. Nonsteroidal anti-inflammatory drugs may have adverse reactions or may be contraindicated. Short-term use of antibiotics to alleviate pain can be of clinical benefits in these patients. How to cite this article Alsomadi L, Al Habahbeh R. Role of Prophylactic Antibiotics in the Management of Postoperative Endodontic Pain. J Contemp Dent Pract 2015;16(12):939-943.

scholarly journals A comparative clinical study to access the role of Basti and Virechana Karma followed by Rasayana in post menopausal Asthikshaya (Osteoporosis)

2020 ◽  
Vol 5 (05) ◽  
pp. 96-103
Author(s):  
Deepa S. Patil ◽  
Prashanth A.S
Keyword(s):  
Clinical Study ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Post Menopausal ◽  
Group B

Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.

The role of tolvaptan in prevention of hyponatremia in patients undergoing transurethral resection of prostate surgery- A randomized double blind study

2021 ◽  
Vol 8 (2) ◽  
pp. 321-325
Author(s):  
Dinesh Kumar Singh ◽  
B B Baj ◽  
Vipin Goyal
Keyword(s):  
Transurethral Resection ◽  
Blind Study ◽  
Transurethral Resection Of Prostate ◽  
Double Blind Study ◽  
Double Blind ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B

The aim of our study to determine the role of tolvaptan in prevention of hyponatremia in transurethral resection of prostate surgery. This is randomized double-blind study conducted in 60 ASA grade status 1 and 2 patients age group between 45-80 yrs undergoing TURP under spinal anaesthesia in urology operation theatre in Mahatma Gandhi hospital Jaipur after receiving permission from hospital ethical committee. A detailed history, complete physical examination and routine investigation were done for all patients followed by informed written consent was obtained. Patients are randomly divided into 2 groups. In group A -30 patients who received orally tab tolvaptan 15 mg and group B-30 patients who received orally tab multivitamin 2 hrs before surgery after doing electrolytes of the patients in the morning. In both groups age (in yrs), wt (in kg), ASA grade, volume of irrigating fluid (in litres), volume of prostate resected (in gm) and duration of surgery (in minutes) all demographic and surgical details data were compared. Electrolytes were compared in both groups pre and post-operatively and statistical analysis was done.There was significant difference in post-operative sodium level between the two groups (A and B). The mean level of sodium significantly reduced post-operatively in group –B (control grp). The mean level of sodium significantly increased post-operatively in group –A (tolvaptan grp). We conclude single dose of tolvaptan -15 mg found to effective in prevention of hyponatremia in patients undergoing TURP.

scholarly journals Role of Immediate Release and Delayed Release Omeprazole in Patients with Gastro Esophageal Reflux Disease

2017 ◽  
Vol 11 (2) ◽  
pp. 67-73
Author(s):  
Mahabub Rahman ◽  
Dewan Saifuddin Ahmed ◽  
Syeda Nur E Jannat ◽  
MM Shahin Ul Islam ◽  
Abu Ahmed Abdullah
Keyword(s):  
Reflux Disease ◽  
Immediate Release ◽  
Esophageal Reflux ◽  
Double Blind ◽  
Delayed Release ◽  
End Of Treatment ◽  
Significant Difference ◽  
Group A ◽  
Group B

Proton pump inhibitors are widely used for Gastro Esophageal Reflux Disease (GERD) treatment. This prospective double blind randomized cross over study was carried out in the Department of Gastroenterology, BSMMU from June 2007 to May 2008 to assess the efficacy of Immediate-release omeprazole (IR-OMEP) & Delayed-release Omeprazole (DR-OMEP) in relieving symptoms & healing of oesophagitis in GERD. All patients who fulfilled the inclusion criteria underwent upper gastrointestinal (UGI) endoscopy to be lebelled as nonerosive and erosive GERD. Among total 69 patients, 43 (62.3 %) had nonerosive and 26 (37.7 %) had erosive GERD. Patients were divided into group A (35) and group B (34) who received group A drugs (20 mg IR-OMEP bd) and group B drugs (20 mg DROMEP bd) from day 1-14 respectively. Then drugs were crossed over (group A: 20mg DR-OMEP bd; group B: 20 mg IR-OMEP bd) from day 15-28. Improvement of heartburn, regurgitation in each group were assessed in every week, during drug cross over and at the end and then compared between two groups. There was no significant difference in relieving heartburn and regurgitation between IR-OMEP and DR-OMEP either in erosive or nonerosive GERD (P>0.50). Patients with erosive GERD underwent UGI endoscopy at the end of treatment to see healing of esophagitis. Study showed significant healing of oesophagitis in group A after 4 weeks than group B (14%) (P<0.05) but there is no superiority of IR-OMEP over DR-OMEP in relieving symptoms of GERD.Faridpur Med. Coll. J. Jul 2016;11(2): 67-73

scholarly journals To assess the role of lingual flap for the removal of lower wisdom tooth.

2020 ◽  
Vol 27 (08) ◽  
pp. 1656-1663
Author(s):  
Noman Ahmed ◽  
Almas Rahoojo ◽  
Syed Zafar Abbas ◽  
Syed Ghazanfar Hassan ◽  
Zunair Memon
Keyword(s):  
Nerve Injury ◽  
Maxillofacial Surgery ◽  
Sensory Nerve ◽  
Lingual Nerve ◽  
Control Group ◽  
Wisdom Tooth ◽  
Significant Difference ◽  
Group A ◽  
Group B

Objectives: To assess the role of lingual flap in encountering lingual nerve injury during the surgical elimination of lower wisdom tooth. Study Design: Cross Sectional Case Control study. Setting: Department of Oral & Maxillofacial Surgery, Institute of Dentistry, Liaquat University of Medical & Health Sciences Jamshoro / Hyderabad. Period: January 2016 to September 2016. Material & Methods: Subjects were categorized into two categories: Group-A (lingual flap) & group-B (control group) each having 52 patients by Lottery method. In group A an envelope mucoperiosteal flap followed by lingual flap elevation carried out and in group B only envelope flap was carried out. All patients were reviewed on the first postoperative day and again 1 and 3rd week after surgery. At each postoperative visit, patient was examined for sensory nerve impairment of the lingual nerve by same observer. Results: Total 104 cases were studied, all the cases categorized among two groups 52 in each group. In group-A 34 were males and 18 were females, while in group-B 44 were male and 8 were females. There was no significant difference among both groups according to the pre-operative assessment. According to objective findings, lingual nerve paresthesia was found among 2 cases of group A on 1st visit, while no any case was found with nerve injury in group B. Out of 2 cases, one case was improved and only one had presented with complain at 2nd visit and 3rd visit, no significant difference among both groups, p-values were quite insignificant. Conclusion: It was concluded that lingual nerve injury (LNI) occurred among few cases of lingual flap group which was insignificantly higher as compare to control group, but the nature of injury was temporary.

scholarly journals A comparative clinical study between intra-caesarean and interval intra uterine copper device insertion in caesarean deliveries

2019 ◽  
Vol 8 (10) ◽  
pp. 3874
Author(s):  
Geetha Lakshmi R. ◽  
Sornam M. S. ◽  
Thenmozhi G.
Keyword(s):  
Clinical Study ◽  
Infection Rate ◽  
Family Welfare ◽  
Uterine Perforation ◽  
Expulsion Rate ◽  
Insertion Method ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Background: Health and family welfare of Indian Ministry, emphasis on postpartum IUCD insertion. Here we conducted a clinical study comparing intra-caesarean and interval CuT-380A insertion in caesarean deliveries.Methods: A systematic study with 150 patients in each group, recruited clients alternately. Group A Intra-Caesarean Cu-T insertion and Group B Interval Cu-T insertion in caesarean deliveries. Groups were followed up at 6th week and 6th month post insertion with a set of parameters. Missed strings, expulsion and infection rates were the primary outcome measures.Results: Infection rate is higher in Group A (2.3%) at 6th week, and at 6th month infection rate is higher in Group B (1.8%). Missed strings are higher in intra-caesarean than in interval insertion method both at 6th week and 6th month follow up p=0.000, hence significant. Expulsion rate is higher in Group A (2.5%) at 6th week, and at 6th month expulsion rate is higher in Group B (1.9%). There are no complications such as uterine perforation or contraceptive failures in both the groups during the study period. By analysis, there are no significant differences in infection and expulsion rates between the groups. For missed strings there is significant difference between the groups with more missed strings in intra-caesarean insertion method.Conclusions: To conclude, intra-caesarean method is equally effective as interval IUCD insertion method without added complications in caesarean deliveries, with advantage of high motivation, good compliance, safety and ease for the provider to deliver services. 

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF LAVANGADI GUTIKA AND PIPPALYADI GUTIKA IN KAPHAJA KASA

2021 ◽  
Vol 9 (10) ◽  
pp. 2347-2352
Author(s):  
Risin Sugunan ◽  
Zenica D’souza
Keyword(s):  
Clinical Study ◽  
Chronic Bronchitis ◽  
Early Management ◽  
Normal Life ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
The Subject ◽  
Group B

Kasa is one of the Pranavaha Srothodusti vikara which hinders normal life. Kaphaja Kasa is a type of Kasa with Vata and Kapha as predominant doshas and present with Prabhuta, Ghana and Bahala kapha. Kaphaja Kasa can be best compared with Chronic Bronchitis. If left untreated it leads to various conditions like Swasa, Kshaya, Chardi, Svarasaadha etc. This signifies the importance of its early management. The present study was conducted on 40 diagnosed subjects of Kaphaja Kasa who were randomly allocated into 2 groups with 20 patients each. La- vangadi gutika was taken in Group A and Pippalyadi gutika in Group B. Medicines was given for 30 days and the data was collected from the subject at baseline, 16th day, 31st day and on 46th day (follow up). The result of the study showed that there was a statistically significant difference in the assessment parameters in both the groups from baseline. However no statistically significant difference was observed between the effect of Lavangadi guti- ka and Pippalyadi gutika in the management of Kaphaja Kasa suggesting that both interventions were having a significant effect on the condition.

scholarly journals A COMPARATIVE CLINICAL STUDY OF ISHTIKA SWEDA AND NADI SWEDA ALONG WITH RASNADI GUGGULU IN THE MANAGEMENT OF VATAKANTAKA

2021 ◽  
Vol 9 (9) ◽  
pp. 2021-2028
Author(s):  
Gouri Tanksali ◽  
Uma Patil
Keyword(s):  
Clinical Study ◽  
Treatment Modalities ◽  
Treatment Methods ◽  
Calcaneal Spur ◽  
Comparative Clinical Study ◽  
Group A ◽  
High Heels ◽  
Group B

Vatakantaka is one of the Vata Vyadhi which gives pricking pain in the heels and causes discomfort in the day-to- day activities. It can be co-related with Calcaneal Spur. It is caused due to wearing high heels and walking with bare feet. Among the various treatment modalities, Abhyanga and Sweda is the best treatment for Vata vyadhi. Hence the present study brings to light the role of Swedana along with Rasnadi Guggulu in the management of Vatakantaka. To evaluate the effect of Istika sweda over Nadi Sweda along with Rasnadi guggulu in management of Vatakantaka. In the present study, 40 patients of vatakantaka were selected incidentally and placed randomly into two groups A and B, with 20 subjects in each group. Group A was treated with Istika Sweda, and Group B were treated with Nadi Sweda along with Rasanadi Guggulu as shamanoushadi for both groups. The effects of treatment provided to the subjects of both groups were significant. Both the treatment methods of Ishtika Sweda and Nadi Sweda showed equally significant effects in the subjects involved in a clinical study. Keywords: Vatakantaka, Calcaneal Spur, Ishtika sweda, Nadi sweda, Rasnadi guggulu.

scholarly journals Protective Role of Different Local Spices on Lambda Cyhalothrin Induced Nephrotoxicity in Male Mice

2021 ◽  
pp. 61-70
Author(s):  
Eme Efioanwan Orlu ◽  
Adetutu Olubunmi Obulor
Keyword(s):  
Experimental Design ◽  
Total Protein ◽  
Protective Role ◽  
Male Mice ◽  
Lambda Cyhalothrin ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Animal House

Aim: This study was aimed at evaluating the protective role of different local spices on lambda cyhalothrin induced nephrotoxicity in male mice Experimental Design: A completely randomized experimental design using standard methods for analysis. Place and Duration of Study: This study was carried out in the Animal house, Department of Animal and Environmental Biology of Rivers State University, Nkpolu-Oroworukwo Port Harcourt, Nigeria. GPS 4o47'50''N 6o58'49''E. This study lasted for 35days. Methodology: The experimental animals were separated into 6 groups (A-F) of seven mice each. Group A served as the control and Group B – F served as the test groups. At the end of the 35 day treatment period, feed was withdrawn from the mice 24 hours before termination of the experiment. Blood samples for analysis of kidney function test were collected from each mouse by ocular puncture into plain tubes. The blood was allowed to clot and centrifuged at 2500g to separate the serum from the cells. Total protein was analyzed using the spectrophotometric method of biuret, Bradford and erythrosine – b, albumin was estimated, creatinine and urea was done using enzymatic method. Vital organs were removed and weighed for organosomatic indices. Histological sections of the kidney were mounted on slides, stained with hematoxylin and eosin (H&E). Photomicrographs were generated. Results: There is no significant difference (P=0.05) between the organ weight and bodyweight in group A compared with the treatment groups. The values of Albumin, total protein, urea, creatinine and total bilirubin increased significantly in group B administered lambda cyhalothrin alone but decreased in groups administered the local spices. Histopathological analysis of the kidney shows the regular structure of the kidney architecture in group A, tubular degeneration and several vacuolations were observed in group B. However, less degeneration of the epithelial cells, regeneration of renal tubular epithelium were observed in groups C- F. Conclusion: Based on the results from liver biomarkers and histological micrographs from this study, pronounced degeneration was observed in the kidney cells exposed to lambda-cyhalothrin only. Moreover, all spices used had a regenerating ability on the kidney tubules. It is advocated therefore that consumption of this spices either singly or in combination should be encouraged especially for those exposed to insecticides poisoning

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