Reduction of Aflatoxin –B1 in Cocoa Beans Contaminated with Aspergillus Flavus by the Essential Oil of Aframomum Danielli Using Response Surface Methodology

2011 ◽  
pp. 401-417
Author(s):  
Aroyeun Shamsideen Olusegun ◽  
◽  
Adegoke Gabriel Olanrewaju ◽  
Varga Janos ◽  
◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Response Surface ◽  
Aspergillus Flavus ◽  
Aflatoxin B1 ◽  
Cocoa Beans

Response Surface Methodology towards Optimization of Calotropis Procera Essential oil Extraction by using Supercritical CO2.

2019 ◽  
Vol 09 ◽  
Author(s):  
Hossein Zaeri ◽  
Bahareh Kamyab Moghadas ◽  
Bijan Honarvar ◽  
Ali Shokuhi Rad
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Response Surface ◽  
Extraction Time ◽  
Calotropis Procera ◽  
Retrieval Rate ◽  
The Family ◽  
Effects Of Temperature ◽  
Carbon Dioxide Co2 ◽  
Central Composite

: In this research, the extraction of essential oil from Calotropis Procera with the family name of Asclepiadaceae, by supercritical carbon dioxide (CO2) solvent has been investigated in detail, and the yield and chemical profile of the extracts achieved by this method were compared with those resulted by the conventional Hydro distillation method. To optimize the process parameters of CO2 supercritical extraction (SCE) of the Calotropis Procera, the Response Surface Methodology (RSM) with central composite design (CCD) was employed. The effects of temperature, pressure, and extraction time on the oil yield are considered for investigation. Results showed that the data were sufficiently fitted into the second-order polynomial model. The extraction conditions, including pressure, temperature, and extraction time, were studied between 150-200 bar, 40-50 ºC, and 50-100 min, respectively. The optimal conditions are achieved as the temperature of 47.19ºC, the pressure of 172.2 bar, and time of 86 minutes with the retrieval rate of 31.39%.

scholarly journals Extraction of ‘Gannanzao’ Orange Peel Essential Oil by Response Surface Methodology and its Effect on Cancer Cell Proliferation and Migration

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 499 ◽  
Author(s):  
Ke Liu ◽  
Weihui Deng ◽  
Wei Hu ◽  
Shan Cao ◽  
Balian Zhong ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Cancer Cells ◽  
Response Surface ◽  
Chloride Concentration ◽  
Orange Peel ◽  
Cell Counting ◽  
Dependent Inhibition ◽  
And Migration ◽  
Total Oil

The essential oil of ‘Gannanzao’ orange peel was extracted by hydrodistillation, and the extraction conditions were optimized by Box–Behnken response surface methodology. The components of essential oil were analyzed by GC-MS. Thirty-nine different components were detected, accounting for 99.59% of the total oil. Limonene (88.07%) was the prominent component. The optimal extraction conditions were as follows: liquid material ratio of 8.4:1 (mL/g), sodium chloride concentration of 5.3%, and distillation time of 3.5 h. The Cell Counting Kit-8 assay showed that ‘Gannanzao’ orange peel essential oil had good dose-dependent inhibition effect on the proliferation of HepG2 hepatoma cells and HCT116 colorectal cancer cells. When the concentration of the essential oil was 0.6 μL/mL or higher, the viability rate of both cancer cells became lower than 13.0%. The transwell assay indicated the essential oil can inhibit migration of both cancer cells at the concentration of 0.3 μL/mL.

Improving the stability of uricase from Aspergillus flavus by osmolytes: Use of response surface methodology for optimization of the enzyme stability

2020 ◽  
Vol 94 ◽  
pp. 86-98 ◽  
Author(s):  
Somayyeh Mirzaeinia ◽  
Mohammad Pazhang ◽  
Mehdi Imani ◽  
Nader Chaparzadeh ◽  
Ali Reza Amani-Ghadim
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Aspergillus Flavus ◽  
Enzyme Stability ◽  
The Stability

scholarly journals Application of Response Surface Methodology for the Optimization of Essential Oils from Pomelo [Citrus grandis (L.) Osbeck] Leaves using Microwave-Assisted Hydrodistillation Method

2019 ◽  
Vol 31 (8) ◽  
pp. 1639-1642 ◽  
Author(s):  
TAN PHAT DAO ◽  
THIEN HIEN TRAN ◽  
Duy Trinh Nguyen ◽  
Duy Chinh Nguyen ◽  
Dai Hai Nguyen ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Essential Oils ◽  
Response Surface ◽  
Favourable Outcome ◽  
Quadratic Model ◽  
P Value ◽  
Microwave Assisted ◽  
New Methods ◽  
Essential Oil Yield

Pomelo leaves oil has many applications regarding hair nourishment and stimulation. Recently, new methods of extracting essential oil used have been increasingly developed to replace traditional methods. In this research, maximization of essential oils yield from Citrus grandis was studied by the combination of microwave assisted hydro-distillation (MAHD) and response surface methodology (RSM). We found that the maximum essential oil yield was 0.3197 % with 91.3 % desirability corresponding to factors such as material and water ratiosof 3.04:1, extraction time at 62.76 min and microwave power of 482.17 W. ANOVA analysis for quadratic model also gives favourable outcome including the high determination coefficient (R2 = 0.9443), significant F-value and p-value of coefficients. All these values indicate that this model is significant between experimental and predicted variables.

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