scholarly journals Knowledge, Attitude and Behavior of Women toward Abnormal Menstrual Bleeding and Its Impact on Quality of Life

2015 ◽  
Vol 7 (1) ◽  
pp. 5-9
Author(s):  
Harpreet Kaur ◽  
Sushmita Sharma ◽  
SPS Goraya
Keyword(s):  
Quality Of Life ◽  
Treatment Strategies ◽  
Abnormal Uterine Bleeding ◽  
Menstrual Bleeding ◽  
Treatment Modalities ◽  
Patient’S Satisfaction ◽  
Abnormal Bleeding ◽  
And Behavior ◽  
The Impact

ABSTRACT Abnormal menstrual bleeding (AMB) is a common gynecological complaint. It may have serious repercussions on women's quality of life. Most of the studies on abnormal menstrual bleeding focus on the quantity of blood loss with little emphasis on the effect, it has on the quality of women's life. Recent research in the area of abnormal menstrual bleeding has recognized the importance of the ‘patient experience’ as an outcome that should be measured. So, it is very important to know about women's perception about the problem so that the healthcare professional can provide them appropriate care. The present study was undertaken to assess effect of AMB on various aspects of women's life and to assess their knowledge toward causes and management of AMB and its health impacts. Though majority of women know about abnormal bleeding as something serious, but still they lack in depth understanding of its consequences and various treatment modalities available. Significance for public research The article gives us valuable inputs regarding patient's viewpoint about abnormal uterine bleeding. Knowing the patients perceptions, their attitude toward abnormal menstrual bleeding and various social factors affecting it may be very helpful for the health professionals and researchers in knowing the impact of abnormal bleeding on quality of life and hence selecting the treatment strategies that will improve patient's satisfaction. How to cite this article Kaur H, Sharma S, Goraya SPS. Knowledge, Attitude and Behavior of Women toward Abnormal Menstrual Bleeding and Its Impact on Quality of Life. J South Asian Feder Obst Gynae 2015;7(1):5-9.

Bipolar Disorders and Their Clinical Management, Part II: Diagnosis, Differential Diagnosis, and Treatment

2019 ◽  
Author(s):  
Bernadette DeMuri-Maletic ◽  
Vladimir Maletic
Keyword(s):  
Quality Of Life ◽  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Bipolar Disorders ◽  
Psychosocial Interventions ◽  
Diagnosis And Treatment ◽  
Treatment Quality ◽  
Treatment Modalities ◽  
The Impact

Bipolar disorder is a biologically and phenotypically diverse disorder and its diagnosis and treatment provides a significant challenge to even the most seasoned clinician. We provide an update on the diagnosis and differential diagnosis of bipolar disorder, reflecting recent changes in DSM-5. Our review provides a succinct summary of the treatment literature, encompassing pharmacologic and psychosocial interventions for bipolar depression, mania/hypomania, mixed states, and prevention of disease recurrence. We provide a brief critical review of emerging treatment modalities, including those used in treatment resistance. Challenges involved in maintaining adherence are further discussed. Additionally, we review common treatment adverse effects and provide recommendations for proper side effect monitoring. There is evidence of significant functional impairment in patients with bipolar disorder and we conclude with a discussion of the impact of impairment on prognosis and quality of life. This review contains 4 figures, 8 tables, and 45 references. Key Words: bipolar disorders, differential diagnosis, maintenance pharmacotherapy, prognosis, psychosocial interventions, treatment, quality of life

A Citizen's View of the Impact of Crime

1969 ◽  
Vol 15 (3) ◽  
pp. 323-332
Author(s):  
Julia D. Stuart
Keyword(s):  
Quality Of Life ◽  
Criminal Behavior ◽  
Fear Of Crime ◽  
The United States ◽  
Point Of View ◽  
Corrosive Effect ◽  
And Behavior ◽  
Direct Encounter ◽  
The Impact

What is the impact of crime on the average individual in this country? What is the impact of the fear of crime on the quality of life in the United States? These questions are addressed in this article not from the point of view of an expert, or of an official in the criminal justice system, or of a victim of crime, but from that of an average person whose experience has included no direct encounter with crime of any kind. Those who have been victims of crime and those affected even indirectly by criminal behavior will react, naturally, with predictable concern; crime also has discernible effects on the attitudes and behavior of people generally, and this impact in turn has a corrosive effect on the quality of life in America.

scholarly journals SAT-427 Quality of Life Following Treatment for Graves’ Disease: A Comparison of Radioactive Iodine Ablation and Surgery

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Christopher W Rowe ◽  
Nicholas D Blefari ◽  
Natalie Rutherford ◽  
Cino Bendinelli ◽  
Chris O’Neill
Keyword(s):  
Quality Of Life ◽  
Family Relationships ◽  
Radioactive Iodine ◽  
Physical Symptom ◽  
Treatment Modalities ◽  
Graves Disease ◽  
Tertiary Institution ◽  
Cross Sectional ◽  
The Impact

Abstract Introduction: Quality of Life (QoL) is reduced in patients with Graves’ disease, however the impact of treatment modality is unclear, with conflicting evidence from recent studies (1–3). We hypothesized that surgery would have a greater impact than radioiodine on QoL in Graves’ disease, especially with regard to the physical-symptom subdomain. Methods: Patients treated with thyroid surgery for benign disease (n=425) or radioactive iodine for hyperthyroidism (n=1637) at a single tertiary institution between 2000 and 2017 were invited to complete a validated thyroid-specific QoL instrument (City of Hope), reporting scores 0–10, where higher scores are associated with greater QoL. Responses were received from 307 patients, of whom 114 (37%) had Graves’ disease, treated with total thyroidectomy (n=23) or doses of 15mCi (550MBq) radioiodine (n=91, including 19 patients receiving 2 or more doses). The results of patients with Graves’ disease are reported here. Medians [interquartile ranges] are compared with the Mann-Whitney test (alpha 0.05). Results: 85% of respondents were female, with no difference in gender between groups (p=0.11). Thyroidectomy patients were more likely to be younger (36 [31–49] vs 50 [39–59] years, p=0.004); and have a shorter duration between treatment and survey (5.9 [2.4–9.6] vs 7.6 [4.9–11.6] years, p=0.04). No overall QoL deficit was seen in patients treated with surgery compared to radioiodine (6.8 [5.2–7.3] vs 7.0 [5.8–8.1], p=0.08). However, patients treated with surgery reported reduce QoL in psychological (6.6 [4.7–7.5] vs 7.0 [5.9–8.2] p=0.05) and social (7.9 [6.4 – 8.9] vs 8.9 [7.4–9.8] p=0.01) subdomains compared to radioiodine-only treated patients. Within the social subdomain, the QoL detriment was driven by lower scores relating to questions regarding impact on personal and family relationships, support, and isolation (p<0.001), and not by impact on activities of daily living or employment concerns. Interestingly, there was no between group difference in the physical symptom subdomain (p=0.16). QoL differences between treatment modalities were preserved when patients receiving multiple doses of radioiodine were excluded. Discussion In this non-randomised cross-sectional study from a tertiary-hospital population in Australia, a QoL deficit was demonstrable in subdomain scores for patients with Graves’ disease treated with surgery compared to radioiodine, although the overall result was not significantly different. Better understanding of patient experiences is required to guide treatment strategies and appropriately counsel patients. References (1) Torring et al. Thyroid. 2019;29(3):322–31. (2) Abraham-Nordling et al. Thyroid. 2005;15(11):1279–86. (3) Ljunggren et al. Thyroid. 1998;8(8):653–9.

scholarly journals Evidence-Based Minireview: Abnormal uterine bleeding in users of rivaroxaban and apixaban

Hematology ◽  
2020 ◽  
Vol 2020 (1) ◽  
pp. 538-541
Author(s):  
Amanda E. Jacobson-Kelly ◽  
Bethany T. Samuelson Bannow
Keyword(s):  
Quality Of Life ◽  
Observational Studies ◽  
Oral Anticoagulants ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Evidence Based ◽  
Substantial Impact ◽  
Menstruating Women ◽  
The Impact

Abstract Up to two-thirds of menstruating women experience abnormal uterine bleeding (AUB) when treated with oral anticoagulants. However, the true prevalence of AUB for specific agents remains uncertain, as many of these episodes, while interfering significantly with quality of life and overall health, are not captured by definitions of major bleeding (MB) or clinically relevant nonmajor bleeding (CRNMB) used in clinical trials. A 2017 systematic review determined that women taking rivaroxaban, but not edoxaban or apixaban, had a twofold higher risk of AUB than women taking warfarin. Since then, new data have become available from extension trials, cancer-associated venous thromboembolism trials, pediatric trials, and a few observational studies specifically examining AUB as an outcome. Reported rates of uterine CRNMB were low (around 1%) and similar for rivaroxaban and apixaban in all these studies, and no episodes of uterine bleeding meeting MB criteria were reported. Rates of AUB not meeting MB or CRNMB criteria were much higher, affecting up to 50% of women on rivaroxaban. Only 1 such study included women on apixaban, and no AUB was reported. In pediatric trials, 19% of girls experienced menorrhagia when treated with rivaroxaban. In conclusion, rates of uterine MB and CRNMB were low in all studies, but rates of other types of AUB not meeting these criteria ranged from 15.8% to 50%. We conclude that AUB is underreported due to the limitations of MB/CRNMB criteria despite its substantial impact on quality of life. We urge future investigators to include broader definitions of AUB to better capture the impact of this outcome in menstruating women treated with oral anticoagulants.

Bipolar Disorders and Their Clinical Management, Part II: Diagnosis, Differential Diagnosis, and Treatment

2019 ◽  
Author(s):  
Bernadette DeMuri-Maletic ◽  
Vladimir Maletic
Keyword(s):  
Quality Of Life ◽  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Bipolar Disorders ◽  
Psychosocial Interventions ◽  
Diagnosis And Treatment ◽  
Treatment Quality ◽  
Treatment Modalities ◽  
The Impact

Bipolar disorder is a biologically and phenotypically diverse disorder and its diagnosis and treatment provides a significant challenge to even the most seasoned clinician. We provide an update on the diagnosis and differential diagnosis of bipolar disorder, reflecting recent changes in DSM-5. Our review provides a succinct summary of the treatment literature, encompassing pharmacologic and psychosocial interventions for bipolar depression, mania/hypomania, mixed states, and prevention of disease recurrence. We provide a brief critical review of emerging treatment modalities, including those used in treatment resistance. Challenges involved in maintaining adherence are further discussed. Additionally, we review common treatment adverse effects and provide recommendations for proper side effect monitoring. There is evidence of significant functional impairment in patients with bipolar disorder and we conclude with a discussion of the impact of impairment on prognosis and quality of life. This review contains 7 tables and 45 references. Key Words: bipolar disorders, differential diagnosis, maintenance pharmacotherapy, prognosis, psychosocial interventions, treatment, quality of life

scholarly journals Neuropsychological assessment and quality of life in patients with refractory temporal lobe epilepsy related to hippocampal sclerosis

2006 ◽  
Vol 12 (4) ◽  
pp. 201-206 ◽  
Author(s):  
Marcele Araujo Silva Mantoan ◽  
Tatiana Indelicato da Silva ◽  
Neide Barreira Alonso ◽  
Maria Helena da Silva Noffs ◽  
Carolina Mattos Marques ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Neuropsychological Assessment ◽  
Hippocampal Sclerosis ◽  
Complex Partial Seizures ◽  
Cognitive Difficulties ◽  
And Behavior ◽  
The Impact

INTRODUCTION: Epilepsy is a disorder that results in abnormal activity in a group of neurons that may have significant impact on the normal cognitive processes and behavior. Temporal lobe epilepsy (TLE) is the most frequent form of partial epilepsy in adults, and hippocampal sclerosis (HS) the most common neuropathologic finding in patients with medically refractory TLE. Patients with TLE often present cognitive difficulties that may be determined by the effects of epileptic discharges and side of the lesion. And its consequence is that patients have poor effects on quality of life (QOL). PURPOSE: We report the relationship between neuropsychological assessment and QOL under the hypotheses that patients with worst results in neuropsychological assessment have poorer QOL assessed by the QOLIE-31. RESULTS: Regarding seizure frequency, 23 (46%) had had 1-5, 20 (40%) 6-10 and 7 (14%) more than 10 seizures/month. In relation to seizure types, 5 (10%) had had auras, 37 (74%) complex partial seizures and 8 (16%) partial evolving to generalized tonic-clonic seizures (GTCS). Neuropsychological evaluation had a positive correlation with QOLIE-31 domains. QOL evaluations had the worst scores in QOLIE-31 were in Cognitive Function (45.0) and Social Function (46.0). The best was Overall QOL (62.0). CONCLUSION: People with epilepsy have great impact on their QOL not only because of daily seizures but because of the impact seizures cause in their cognitive functions. TLE is an example of how refractory epilepsy can exterminate any possibilities of work, study and live in a society that discriminates someone with epilepsy who also presents cognitive decline.

Introduction: The Impact of Continuous Levodopa Infusion in the Treatment of Parkinson's Disease

CNS Spectrums ◽  
2008 ◽  
Vol 13 (S7) ◽  
pp. 3-3 ◽  
Author(s):  
Erik Wolters
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Treatment Strategies ◽  
Resting Tremor ◽  
Endogenous Dopamine ◽  
Dopamine Signaling ◽  
The Impact ◽  
Dopaminergic Stimulation

Parkinson's disease was first described in 1817 by James Parkinson. Based on his observation of only six individuals, Parkinson accurately described the resting tremor and festinate gait, bradykinesia, and postural instability associated with the disease today. Parkinson's disease primarily affects people >50 years of age and causes progressive neurological degeneration, physical disability, and worsening quality of life.Consequently, most currently available drugs aim to restore striatal dopamine signaling. This can be best reached by increasing the supply of dopamine with oral levodopa (L-dopa), but also by stimulating dopamine receptors directly using dopamine agonists, or by inhibiting the reuptake of endogenous dopamine. Unfortunately, mainly due to the short half-life of L-dopa and the erratic absorption of oral L-dopa (causing pulsatile dopaminergic stimulation) these treatment strategies become increasingly ineffective in the course of this disease, and motor complications may further reduce the quality of life in these patients.

scholarly journals Overlooked Long-Term Complications of Colorectal Surgery

2019 ◽  
Vol 32 (03) ◽  
pp. 204-211 ◽  
Author(s):  
Matthew Giglia ◽  
Sharon Stein
Keyword(s):  
Quality Of Life ◽  
Colorectal Surgery ◽  
Treatment Strategies ◽  
Autonomic Nerve ◽  
Complication Rates ◽  
Low Anterior Resection Syndrome ◽  
Colon And Rectum ◽  
Surgical Field ◽  
The Impact

AbstractWhile colorectal surgery has been documented to have some of the highest complication rates in the surgical field, some of the more common, functional complications are often overlooked in the literature and in discussion with patients. Urinary, sexual, and defecatory dysfunction are common after colorectal surgery, especially after pelvic dissections, and may severely impact the postoperative quality of life for patients. These complications include urinary retention, erectile dysfunction, retrograde ejaculation, dyspareunia, infertility, and low anterior resection syndrome. The majority is rooted in autonomic nerve damage, both sympathetic and parasympathetic, that occurs during mobilization and resection of the sigmoid colon and rectum. While not all of these postoperative complications are preventable, treatment strategies have been developed to ameliorate the impact on quality of life. Given the high incidence and direct effect on patients, clinicians should be familiar with the etiology, prevention, and treatment strategies of these complications to provide the highest quality of care.

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