Effects of Paeonia albiflora Root Extract on Epidermal Wound Healing

2021 ◽  
Vol 55 (4) ◽  
pp. 331-337
Author(s):  
Shota Hayashi ◽  
Hiroyasu Iwahashi ◽  
Keiko Yashiki ◽  
Akinori Kiso
Keyword(s):  
Wound Healing ◽  
Root Extract

scholarly journals Evaluation of wound healing and antibacterial properties of methanolic root extract of Stephania dinklagei (Engl.) Diels

2015 ◽  
Vol 12 (6) ◽  
pp. 122
Author(s):  
Sunday Ositadimma Udegbunam ◽  
Nnabuike Prince Igbokwe ◽  
Rita Ijeoma Udegbunam ◽  
Theophilus Okafor Nnaji ◽  
Madubuike Umunna Anyanwu
Keyword(s):  
Wound Healing ◽  
Antibacterial Properties ◽  
Root Extract

scholarly journals Wound healing activity of the ethanol root extract and polyphenolic rich fraction fromPotentilla fulgens

2016 ◽  
Vol 54 (11) ◽  
pp. 2383-2393 ◽  
Author(s):  
Anindita Kundu ◽  
Arka Ghosh ◽  
Narendra K. Singh ◽  
Gireesh K. Singh ◽  
Ankit Seth ◽  
...  
Keyword(s):  
Wound Healing ◽  
Root Extract ◽  
Wound Healing Activity

Green synthesis of silver nanoparticles using Arnebia nobilis root extract and wound healing potential of its hydrogel

2014 ◽  
Vol 8 (2) ◽  
pp. 95 ◽  
Author(s):  
Seema Garg ◽  
Amrish Chandra ◽  
Avijit Mazumder ◽  
Rupa Mazumder
Keyword(s):  
Wound Healing ◽  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Root Extract

scholarly journals EVALUATION OF WOUND HEALING ACTIVITY OF ACALYPHA FRUTICOSA ROOT EXTRACT IN RATS

2016 ◽  
Vol 2 (4) ◽  
pp. 1-6
Author(s):  
Afreen Nishath ◽  
Sharavana bhava Bandaru Sheshagiri ◽  
Venkateshwarlu Eggadi
Keyword(s):  
Wound Healing ◽  
Root Extract ◽  
Wound Healing Activity

Topical Wound Healing, Antimicrobial and Antioxidant Potential of Mimosa pudica Linn root Extracted using n-Hexane Followed by Methanol, Fortified in Ointment Base

2021 ◽  
Vol 14 (3) ◽  
pp. 5472-5480
Author(s):  
Sangeeta Singh ◽  
Tanvi R Dodiya ◽  
Sudarshan Singh ◽  
Rajesh Dodiya
Keyword(s):  
Wound Healing ◽  
Ethyl Acetate ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Solvent System ◽  
Perennial Herb ◽  
Maximum Effect ◽  
Root Extract ◽  
Mimosa Pudica ◽  
Ointment Base

Mimosa pudica Linn is an ornamental perennial herb belonging to the taxonomic group of Magnoliopsida and family Leguminaceae. Besides its ornamental use, Mimosa pudica is also a popular plant among folk healers to treat several diseases including bleeding disorders such as menorrhagia, dysentry with blood, mucus and piles, and wound healing. In this study, roots of Mimosa pudica was successively extracted with hexane, ethyl acetate, and methanol to evaluate the folkloric assert of plant in view of antioxidant, antibacterial, and wound healing potential. Methanolic extract showed concentration dependent elevation in inhibition for radical scavenging assay following dpph with maximum effect of 73.43% against standard ascorbic acid equivalent to 250 µg/ml, however IC50 of extract with n-hexane and ethyl acetate exhibited relatively poor antioxidant efficacy. Minimum inhibitory concentration demonstrated higher inhibitory action in range of 1.25-0.625 mg/ml against tested gram positive Staphylococcus aureus -MTCC737, and Bacillus subtilis-MTCC110 and 2.5 mg/ml for gram negative Salmonella typhi-MTCC15442, Escherichia coli-MTCC118 micro-organism for methanolic extract compared to ethyl acetate extract, however hexane extract showed MIC > 2.5 mg/ml. Among the tested solvent system for column chromatography, fractionation with diethyl ether: methanol (1:4) demonstrated single clear spot with Rf value 0.72 for methanolic extract indicated presence of flavonoid as major phytoconstituents. The results of spectral analysis following fourier transform spectroscopy, nuclear magnetic resonance, and mass spectroscopy for purified isolated compound confirmed identity of isolated flavonoid from methanolic fraction with chemical name 7,8,3’,4’-tetrahydroxy-6-methoxy-flavone. Thus, overall results demonstrated that Mimosa pudica root extract have potential antioxidant and antimicrobial efficacy. Furthermore, the Mimosa pudica root extracted with n-hexane followed by methanol fortified in a pharmaceutical formulation ointment base demonstrated excellent wound healing efficacy compared to marketed povidone-iodine ointment. Therefore, traditional claim for the use of Mimosa pudica root as potential antioxidant, antimicrobial, and wound healer in topical drug delivery have been proven by the present study. 

Wound-Healing Potential of the Root Extract of Albizzia lebbeck

Planta Medica ◽  
2013 ◽  
Vol 79 (09) ◽  
pp. 737-743 ◽  
Author(s):  
Apurva Joshi ◽  
Nidhi Sengar ◽  
Satyendra Prasad ◽  
Raj Goel ◽  
Akanksha Singh ◽  
...  
Keyword(s):  
Wound Healing ◽  
Root Extract ◽  
Albizzia Lebbeck

scholarly journals Effect of Ficus hispida L. on normal and dexamethasone suppressed wound healing

2011 ◽  
Vol 47 (4) ◽  
pp. 855-860 ◽  
Author(s):  
Krishna Murti ◽  
Vijay Lambole ◽  
Mayank Panchal
Keyword(s):  
Wound Healing ◽  
Dead Space ◽  
Breaking Strength ◽  
Ethanolic Extract ◽  
Control Group ◽  
Albino Rats ◽  
Root Extract ◽  
Control Groups ◽  
Ficus Hispida ◽  
Wound Healing Activity

Ethanolic extract of roots of Ficus hispida was investigated in normal and dexamethasone depressed healing conditions, using incision, excision and dead space wound models in albino rats. The root extract of Ficus hispida has shown the maximum breaking strength compared to control group. The rate of epithelialization and wound contraction in excision model was better as compared to control groups. There was significant increase in granulation tissue weight and hydroxyproline content in dead space model compared to control group. The antihealing effect of dexamethasone was also reverted by the administration of ethanolic extract of Ficus hispida in all the wound models .The results indicated that the root extract of Ficus hispida has a significant wound healing activity and also promotes healing in dexamethasone depressed healing conditions.

scholarly journals Hydro-Alcoholic Root Extracts of Ziziphus abyssinica is Effective in Diabetes Nephropathy and Diabetic Wound Healing

2021 ◽  
pp. 19-29
Author(s):  
Samuel A. Akwetey ◽  
Douglas B. Aidoo ◽  
Wisdom Ahlidja ◽  
Bright B. Boafo ◽  
Joseph M. Acquah ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Nephropathy ◽  
Blood Glucose ◽  
Blood Glucose Concentration ◽  
Negative Control ◽  
Diabetic Rats ◽  
Histopathological Analysis ◽  
Root Extract ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

Background: This study evaluated the potential of Ziziphus abysinnica root extract in managing hyperglycaemia in type 2 diabetes mellitus (T2DM), diabetic wound healing and diabetic nephropathy. Methodology: Blood glucose concentrations were measured daily for 14 days after daily administrations of either Ziziphus abysinnica (30, 100, and 300 mg/kg, p.o), metformin (300 mg/kg, p.o) or normal saline as negative control before diabetes induction using a single dose of Streptozotocin (60 mg/kg, i.p) and nicotinamide (120 mg/kg, i.p). Histopathological analysis was performed on the harvested kidneys following administration with Ziziphus abysinnica in diabetic rats. The diabetic wound healing potentials of the plant was also evaluated in streptozotocin-induced diabetic rats by treating them with 15%w/w ZAE ointment. Results: Generally, the percentage of blood glucose levels analysed following administration of drugs were found to be dose-dependent. The highest dose of ZAE (300 mg/kg) had a higher percentage reduction in blood glucose concentration when compared to metformin (300 mg/kg).  The lowest dose (30 mg/kg) of ZAE administered attenuated STZ induced pathological damage and showed moderate to maximal improvement to the kidney nephrons. In contrast, the 100 mg/kg and 300 mg/kg dose ZAE demonstrated minimal pathological changes to the kidney architecture. Conclusion: Overall, our study demonstrated the antidiabetic potential of Ziziphus abysinnica, suggesting its possible therapeutic benefit in diabetic wound healing and diabetic nephropathy. 

scholarly journals Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa

2009 ◽  
Vol 03 (02) ◽  
pp. 96-99 ◽  
Author(s):  
H. Huseyin Kosger ◽  
Mustafa Ozturk ◽  
Atalay Sokmen ◽  
Eray Bulut ◽  
Sinan Ay
Keyword(s):  
Wound Healing ◽  
Therapeutic Agent ◽  
Root Extract ◽  
Full Thickness ◽  
Tissue Samples ◽  
Root Extracts ◽  
Palatal Mucosa

ABSTRACTObjectives: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa.Methods: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. Inthe experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically.Results: It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups.Conclusions: This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing. (Eur J Dent 2009;3:96-99)

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