scholarly journals Utilidad diagnóstica de la relación plaquetas/linfocitos en embarazadas con preeclampsia

2021 ◽  
Vol 81 (01) ◽  
pp. 5-12
Author(s):  
Eduardo Reyna-Villasmil ◽  
◽  
Jorly Mejía-Montilla ◽  
Nadia Reyna-Villasmil ◽  
Duly Torres-Cepeda ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Predictive Value ◽  
Control Group ◽  
Study Group ◽  
Diagnostic Efficacy ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio ◽  
A Value ◽  
Group A ◽  
Group B

Objective: To establish the diagnostic utility of the platelet-lymphocyte ratio in pregnant women with preeclampsia. Methods: A case-control study was carried out at the Hospital Central “Dr. Urquinaona” Maracaibo, Venezuela. A total of 180 pregnant women were selected. Ninety preeclamptic women were included as the study group (group A) and a control group selected for their age and body mass index similar to the study group, which consisted of 90 healthy normotensive pregnant women (group B). The general characteristics, platelet-lymphocyte ratio values and diagnostic efficacy were determined. Results: Group A patients presented lower platelet and lymphocyte values compared to group B patients (p <0.001). However, no statistically significant differences were found in platelet-lymphocyte ratio between group A patients (115.2 ± 32.7) and group B patients (122.3 ± 23.8; p = 0, 0971). A cut-off value of the platelets-lymphocyte ratio of 117 presented a value below the curve of 0.57, the sensitivity of 47.8%, the specificity of 50.0%, the positive predictive value of 48.9%, and the negative predictive value of 52.2%, with a diagnostic accuracy of 48.9%. Conclusion: Platelet-lymphocyte ratio is not a useful tool in the diagnosis of preeclampsia, since patients with the syndrome present similar values to normotensive pregnant women. Keywords: Platelet-lymphocyte ratio, Preeclampsia, Diagnosis, Pregnancy.

Serum Hemoglobin Level in Preeclampsia

2021 ◽  
Vol 8 (1) ◽  
pp. 39-43
Author(s):  
Selina Akhtar ◽  
Umme Hafsa Any ◽  
Sonia Fahmi
Keyword(s):  
Pregnant Women ◽  
Hemoglobin Level ◽  
Fetal Mortality ◽  
Control Group ◽  
Study Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Group A ◽  
Group B

Background: Pre-eclampsia is the major cause of maternal and fetal mortality and morbidity. It affects approximately 5-8% of pregnant women. Objectives: The study was undertaken to find an association between Hemoglobin and preeclampsia. Methodology: This cross-sectional study was carried out in the Department of Physiology at Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh from July 2009 to June 2010. For this, 60 pregnant women of preeclampsia, age ranged from 18 to 39 years, more than 20th weeks of pregnancy were included in the study (group B). They were further divided into group B1 consisting of 30 mild preeclamptic women and group B2 consisting of 30 severe preeclamptic women. For comparison age and gestational period matched 30 normotensive pregnant women control (group A) were also studied. Both control (group A) and preeclamptic women were selected from Obstetric and Gynae in and out patient Department of BSMMU and Dhaka Medical College Hospital. Maternal hemoglobin concentration was measured by standard laboratory techniques. Result: In this study, hemoglobin levels were significantly higher in study (group B) than those of control (group A). Again Hemoglobin levels were higher in group B2 than B1, but not significant (P>0.05). Hemoglobin level was positively correlated with systolic and diastolic blood pressure but it was statistically non-significant (P>0.05). Conclusion: The study concluded that serum hemoglobin level is associated with preeclampsia. Journal of Current and Advance Medical Research, January 2021;8(1):39-43]

Does laryngopharyngeal reflux affect healing and recovery after tonsillectomy?

2007 ◽  
Vol 122 (6) ◽  
pp. 603-608 ◽  
Author(s):  
S Elwany ◽  
Y A Nour ◽  
E A Magdy
Keyword(s):  
Wound Healing ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Control Group ◽  
Study Group ◽  
Pain Scores ◽  
Blinded Study ◽  
Group A ◽  
Group B ◽  
Control Group Group

AbstractIntroduction:Laryngopharyngeal reflux is increasingly being implicated in several otolaryngological disorders.Aims:To study a potential correlation between pre-operative laryngopharyngeal reflux and wound healing and recovery after tonsillectomy, based on subjective and objective findings.Materials and methods:A prospective, blinded study was undertaken, including 60 patients scheduled for tonsillectomy, divided into two equal groups: a study group (group A) with pre-operative laryngopharyngeal reflux documented using ambulatory 24-hour pH monitoring; and a control group (group B) without laryngopharyngeal reflux.Results:Group A had significantly higher pain scores on the seventh and 14th post-operative days (p = 0.022 and p = 0.000, respectively) and took a significantly longer time to return to normal eating (p = 0.013), compared with group B. Group A also showed significantly slower healing on the seventh and 14th post-operative days, as estimated by assessing the grade of post-operative slough formation (p = 0.016 and p = 0.029, respectively). A significant correlation between the number of pharyngeal reflux episodes and the degree of post-operative slough was also found.Conclusions:Laryngopharyngeal reflux can significantly decrease wound healing following tonsillectomy. Therefore, pre-operative recognition and management of this condition is desirable in order to eliminate its negative post-operative effect.

scholarly journals Distribution of thyroid peroxidase positivity and its effects on thyroid function in normal pregnant women during 1st trimester in Dhaka city

2014 ◽  
Vol 4 (1) ◽  
pp. 15-20
Author(s):  
Ohida Sultanaa ◽  
Nasim Jahan ◽  
Nayma Sultana ◽  
Farzana Mahmudad ◽  
Tazdik G Chowdhurye
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
First Trimester ◽  
Normal Pregnancy ◽  
Control Group ◽  
Thyroid Peroxidase ◽  
Study Group ◽  
Cross Sectional ◽  
Total Study Population ◽  
Group B

Objective: To measure the distribution of TPO-Ab positivity and to observe the effect of thyroid peroxidase positivity on thyroid function during first trimester in normal pregnancy. Method: A cross sectional among 120 subjects were taken in this study and divided into control and study groups. Control group (Group A) consisted of 60 healthy non pregnant women age ranged between 20 to 35 years. Study group (Group B) consisted of 60 normal pregnant women of same age range. Group B was further subdivided into group B1 and group B2according to the level of TPO-Ab. Group B1 consisted of TPO-Ab positive pregnant women and group B2 consisted of TPO- Ab negative pregnant women. Control group was selected from personal contacts and study group from Out Patient Department (OPD) of Obstetrics and Gynecology of Sir Salimullah Medical College and Mitford Hospital. For assessment of thyroid function, serum free thyroxine (FT4), thyroid stimulating hormone (TSH) were measured. Serum FT4, TSH were measured by Enzyme link immunosorbant (ELISA) method. Again, serum TPO-Ab of total study population and hCG of all the pregnant women were measured. Serum TPO-Ab by Micro particle Enzyme Immunoassay (MEIA) method and hCG was estimated by ELISA. Statistical analysis was done by SPSS version 17. Results: In this study, serum FT4 and was significantly (P<0.001) higher and TSH level was significantly (P<0.001) lower in normal pregnant women during 1st trimester in comparison to those of non pregnant women. Again, 18% of pregnant women showed TPO-Ab positivity. However, serum FT4 level was significantly (P<0.001) lower whereas, TSH level was significantly (p<0.001) higher in TPO-Ab positive pregnant women in comparison to those of TPO-Ab negative pregnant women. Conclusion: TPO-Ab positivity increases during 1st trimester of normal pregnancy which decreases the hyper functional state of thyroid hormones. So, thyroid screening should be done routinely during pregnancy. DOI: http://dx.doi.org/10.3329/updcj.v4i1.21160 Update Dent. Coll. j: 2014; 4 (1): 15-20

scholarly journals Effect of transcutaneous electrical nerve stimulation with stretching and exercises in restless leg syndrome among pregnant women

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
S Jenifer Augustina ◽  
MG Kaviya ◽  
D Indrani
Keyword(s):  
Pregnant Women ◽  
Nerve Stimulation ◽  
Transcutaneous Electrical Nerve Stimulation ◽  
Functional Disability ◽  
Control Group ◽  
Motor Disorder ◽  
Restless Leg Syndrome ◽  
Electrical Nerve Stimulation ◽  
Group A ◽  
Group B

Background: Restless legs syndrome also known as Willis-Ekbom disease is a sensor motor disorder composed of an urge to move with or without associated discomfort that occurs with inactivity and improves with movement. The symptoms occur in leg muscles like calves and thighs. The feet and arms also affected and it causes the functional disability in pregnant women. Sleep disorder is typically the biggest complication of this condition. Unpleasant sensations are deep in the legs. Sensations appear during periods of rest or inactivity particularly in the evening and at night and relived by movement. Prevalence of RLS among pregnant women ranged from 10 to 34%. Aim: The aim of the study is to prove the effect of Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching and Exercises in restless leg syndrome among pregnant women. Objectives: To determine and prove the effectiveness of TENS with stretching to relive pain and improve the functional ability in restless leg syndrome among pregnant women. Materials and Methods: A Quasi-experimental study was conducted on 30 subjects using convenient sampling technique based on inclusion and exclusion criteria. Subjects were allotted into 2 groups i.e., Group A with 15 subjects and Group B with 15 subjects using odd even method of sampling. Experimental group will be treated with TENS and Stretching. Control group will be treated with exercises and massage. Result: Statistical Analysis of Post test for pain and functional performance revealed that patients who received Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching in Group A showed marked improvement compared to patients who received Massage and Exercises in Group B. Conclusion: From the result of the study it concluded that Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching is more effective than massage and exercises in subjects with restless leg syndrome among pregnant women.

scholarly journals Duration of Postoperative Hyperlactatemia Has Predictive Value in Recurrent Fistula After Major Definitive Surgery for Intestinal Fistula

2021 ◽  
Author(s):  
Weiliang Tian ◽  
Shikun Luo ◽  
Xin Xu ◽  
Zheng Yao ◽  
Risheng Zhao
Keyword(s):  
High Risk ◽  
Predictive Value ◽  
Cutoff Point ◽  
Intestinal Fistula ◽  
Recurrent Fistula ◽  
A Value ◽  
Group A ◽  
Definitive Surgery ◽  
Group B

Abstract Purpose The present study aimed to identify the predictive value of duration of postoperative hyperlactatemia in screening patients at high risk of recurrent fistula after major definitive surgery(DS) for intestinal fistula. Methods If the initial postoperative lactate(IPL)> 2 mmol/L, DS was defined as major definitive surgery. The 315 enrolled patients with major DS were divided into group A (2 mmol/L<IPL≤ 4 mmol/L), group B (mmol/L<IPL≤ 6 mmol/L), and group C (IPL>6 mmol/L). The characteristics of patients were collected, and the duration of postoperative hyperlactatemia was analyzed. According to the occurrence of recurrent fistula (RF), patients were further divided into RF group A, and Non-RF group A; RF group B, and Non-RF group B; and RF group C, and Non-RF group C. Results The duration of postoperative hyperlactatemia was comparable between the RF group A and the Non-RF group A [12 (IQR:12-24) vs 24 (IQR:12-24), p=0.387]. However, the duration of hyperlactatemia was associated with RF in group B (adjusted OR= 1.061; 95%CI: 1.029-1.094; p<0.001) and group C (adjusted OR=1.059; 95%CI: 1.012-1.129; p=0.017). In group B, the cutoff point of duration of 42 hours had the optimal predictive value (area under ROC=0.791, sensitivity=0.717, specificity =0.794, p<0.001). In group C, the cutoff point of duration of 54 hours had the optimal predictive value (area under ROC=0.781, sensitivity=0.730, specificity =0.804, p<0.001). Conclusion The duration of postoperative hyperlactatemia has a value in predicting RF in patients with an IPL of more than 4 mmol/L after major definitive surgery for intestinal fistula.

scholarly journals Application Value of Coagulation Function Test in Prognosis of Patients with Cardiovascular and Cerebrovascular Diseases

2021 ◽  
Vol 9 (4) ◽  
pp. 89
Author(s):  
Jing Luo
Keyword(s):  
Cerebrovascular Diseases ◽  
Good Prognosis ◽  
Control Group ◽  
Study Group ◽  
Test Results ◽  
Coagulation Function ◽  
Significant Difference ◽  
Function Test ◽  
Group A ◽  
Group B

<p><span lang="EN-US">Objective: to explore the application value of coagulation function test in the prognosis of patients with cardiovascular and cerebrovascular diseases. Methods: from December 2018 to December 2019, 100 patients with cardiovascular and cerebrovascular diseases were randomly selected as the study group. According to the follow-up results of patients, they were divided into study group A (good prognosis, n = 64) and study group B (disability or death, n = 36) 100 subjects served as the control group. The test results of coagulation function of the two groups were analyzed retrospectively. The test results of the study group before and after treatment were compared with those of the control group, and the test results of the study group A and study group B after treatment were compared. Results: the coagulation function of the study group after treatment was significantly improved compared with that before treatment (P &lt; 0.05), and there was a significant difference between the two groups before treatment (P &lt; 0.05), and there was no difference after treatment (P &gt; 0.05); after treatment, the coagulation function of study group A and study B was significantly different (P &lt; 0.05). Conclusion: coagulation function test has a certain application value for the prognosis of patients with cardiovascular and cerebrovascular diseases, and can be used as an index to judge the patient’s condition and treatment effect, which has good application value in clinical practice.</span></p>

Relationship of Serum Lactate Dehydrogenase (LDH) Level with Severity of Preeclampsia

2016 ◽  
Vol 25 (Number 1) ◽  
pp. 8-14
Author(s):  
R Afroz ◽  
Q S Akhter ◽  
H Sadia ◽  
S Sultana ◽  
F Farid
Keyword(s):  
Lactate Dehydrogenase ◽  
Pregnant Women ◽  
Serum Lactate ◽  
High Serum ◽  
Serum Lactate Dehydrogenase ◽  
Study Group ◽  
Medical College ◽  
Group A ◽  
Severity Of The Disease ◽  
Group B

Preeclampsia is a pregnancy specific disease and associated with multisystem complications. This crosssectional study was carried out in the Department of Physiology, Dhaka Medical College (DMC), Dhakafrom January'14 to December'14 to assess the relationship between serum lactate dehydrogenase (LDH) levelwith the severity of the disease in preeclampsia. For this purpose, a total number of 105 pregnant women atthird trimester (28-40 weeks) with age ranging from 18 to 35 years were selected from DMC Hospital,Dhaka. Among them, 70 pregnant women with preeclampsia were selected as study group (Group B) which wasfurther subdivided as mild preeclamptic women (Group B1) and severe preeclamptic women (Group B2)consisting of 35 subjects in each subgroup. Age matched 35 healthy pregnant women were considered ascontrol group (Group A) for comparison. Serum LDH level was estimated by continuous spectrophotometricmethod. In this study, serum LDH level showed positive correlation with progressive rise of blood pressure inthe study group. The frequency of symptoms and complications of preeclampsia were more in patients with LDH>600 U/L compared with those who had lower levels. The present study showed that high serum LDH levelpositively correlates with the severity of the disease in patients of preeclampsia.

scholarly journals The Effect of Coconut Oil pulling on Streptococcus mutans Count in Saliva in Comparison with Chlorhexidine Mouthwash

2016 ◽  
Vol 17 (1) ◽  
pp. 38-41 ◽  
Author(s):  
Roshni LNU ◽  
Mamta Kaushik ◽  
Pallavi Reddy ◽  
Pooja Udameshi ◽  
Neha Mehra ◽  
...  
Keyword(s):  
Streptococcus Mutans ◽  
Coconut Oil ◽  
Preventive Therapy ◽  
Controlled Study ◽  
Control Group ◽  
Study Group ◽  
Distilled Water ◽  
Group A ◽  
Group B

ABSTRACT Objectives Oil pulling is an age-old practice that has gained modern popularity in promoting oral and systemic health. The scientific verification for this practice is insufficient. Thus, this study evaluated the effect of coconut oil pulling on the count of Streptococcus mutans in saliva and to compare its efficacy with that of Chlorhexidine mouthwash: in vivo. The null hypothesis was that coconut oil pulling has no effect on the bacterial count in saliva. Materials and methods A randomized controlled study was planned and 60 subjects were selected. The subjects were divided into three groups, Group A: Study Group: Oil pulling, Group B: Study Group: Chlorhexidine, and Group C: Control Group: Distilled water. Group A subjects rinsed mouth with 10 ml of coconut oil for 10 minutes. Group B subjects rinsed mouth with 5 ml Chlorhexidine mouthwash for 1 minute and Group C with 5 ml distilled water for 1 minute in the morning before brushing. Saliva samples were collected and cultured on 1st day and after 2 weeks from all subjects. Colonies were counted to compare the efficacy of coconut oil and Chlorhexidine with distilled water. Results Statistically significant reduction in S. mutans count was seen in both the coconut oil pulling and Chlorhexidine group. Conclusion Oil pulling can be explored as a safe and effective alternative to Chlorhexidine. Clinical significance Edible oil-pulling therapy is natural, safe and has no side effects. Hence, it can be considered as a preventive therapy at home to maintain oral hygiene. How to cite this article Kaushik M, Reddy P, Roshni, Udameshi P, Mehra N, Marwaha A. The Effect of Coconut Oil pulling on Streptococcus mutans Count in Saliva in Comparison with Chlorhexidine Mouthwash. J Contemp Dent Pract 2016;17(1):38-41.

scholarly journals Study of Plasma Metanephrine Level As Biochemical Parameter in Pregnant Women with Preeclampsia

2014 ◽  
Vol 11 (2) ◽  
pp. 371-377
Author(s):  
Baghdad Science Journal
Keyword(s):  
Pregnant Women ◽  
Fetal Death ◽  
Protein S ◽  
Biochemical Parameter ◽  
Mean Value ◽  
Control Group ◽  
Protein Ratio ◽  
Gestation Age ◽  
Group A ◽  
Group B

Pregnancy- including hypertension(PIH), also known as preeclampsia, is one of the major causes of maternal and fetal death. This study was carried out on 30 pregnant women with preeclampsia and 30 healthy pregnant women as control ranging in age mean ±SD (28.84±3.55) years , BMI (76.80±9.78) Kg/m2 and gestation age(30.82±0.75)week. The aim of this research was studied the plasma Metanephrine level and other biochemical parameters such as Hemoglobin(Hb), serum Protein, S. Albumin, Globulin, Albumin/Globulin ratio (Alb/Glu. ratio), S.Glutamate Pyruvate aminotransferase (GPT), S.Glutamate Oxaloacetate aminotransferase(GOT). The obtained results have been compared with 30 healthy pregnant women as control group. The result showed that there was significant increase in mean value of Hb in group A(pregnant women with preeclampsia) when compared to group B(healthy pregnant women). The present study showed no significant changes was observed in the level of S. Protein, globulin, Alb./Glu. ratio, GPT and GOT as compared to control group. While Albumin showed a significant decrease in group A(pregnant women with preeclampsia) when compared with group B(healthy pregnant women) and significant increase in the levels of metanephrine, metanephrine/protein ratio, metanephrine/Alb ratio in group A (pregnant women with preeclampsia) to group B(healthy pregnant women).The present study conclude that the increase in the levels of metanephrine, metanephrine/protein ratio, metanephrine/Alb ratio in pregnant women with preeclampsia may be used as a marker to evaluate the development of disease. The current study recommend to take more case and measurement metanephrine in plasma and urine.

scholarly journals RECURRENT ABDOMINAL PAIN

2006 ◽  
Vol 13 (04) ◽  
pp. 563-571
Author(s):  
MUHAMMAD TARIQ NADEEM ◽  
MAZHAR ABBAS ◽  
TAQI HASSAN ◽  
Shahid Masood
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Recurrent Abdominal Pain ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Endoscopic Findings ◽  
Group A ◽  
H Pylori ◽  
Group B

Objective: To assess the association between the Helicobacter Pylori (H.pylori) infection andrecurrent abdominal pain (RAP) by documenting the frequency of Helicobacter pylori infection in children aged 5 to 15years in our setup. Design: A comparative study. Place and Duration of Study: The study was conducted in pediatricunit Military Hospital Rawalpindi over one year period from 1st Apr 200 to 31st Mar 2002. Subject and Methods: Wedivided the patients into two groups; group A or the study group and the group B or the control group. In group A, atotal of 87 Children aged 5 to 15 years presenting with RAP in which no underlying cause was found on initialassessment underwent upper gastrointestinal tract (GIT) endoscopic examination. In group B (control) we included 68children in whom upper GIT endoscopy was done for any reason other than the RAP. In both the groups thegastroduodenal biopsy samples were sent for culture and histological examination for the diagnosis of H. pyloriinfection. The signs and symptoms of these patients were analyzed in detail. Results: In group A, out of 87 patientswho were endoscoped there were 44 female and 43 male. 54(62%) were found positive and 33(38%) were foundnegative for H.pylori on histopathology and culture examination of biopsy samples. In the control group (B) thefrequency of H.pylori infection was 35% (24 of 68) which was significantly lower than the study group (p-value .001).The frequency of H.pylori increased significantly with advancement in age (p-value .003) and lowering of thesocioeconomic status (p-value.002). The commonest endoscopic finding was antral gastritis (31 of 87; 35.6%). Antralnodularity was observed in 8(26%) out of 36 cases of antral gastritis and in 23(74%) cases there was antral erythemawithout nodularity. The remaining endoscopic findings were pan-gastritis (14 of 87;16%), duodenal ulcer (10 of87;11.5%), duodenitis (4 of 87;4.6%) and gastric ulcer (2 of 87;2.3%). The less frequent findings were gastric andduodenal erosions and esophagitis (about 1% each).Their was no abnormal finding in 22(25.3%) cases. Childrenpredominantly (52%) had the symptoms characteristics of ulcer-like dyspepsia. Recurrent epigastric pain wassignificantly more common in the H.pylori positive than the H. pylori negative children (44 of 87 vs 16 of 33 [p-value.001]). There was no difference for other symptom characteristics when comparing infected with non-infected children.Conclusion: The frequency of H.pylori infection is high in children with recurrent abdominal pain and there is a high degree of association between recurrent abdominal pain, endoscopic findings (chronic gastritis, duodenitis, gastric andduodenal ulcer) and the H. pylori infection.

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