scholarly journals RECURRENT ABDOMINAL PAIN

2006 ◽  
Vol 13 (04) ◽  
pp. 563-571
Author(s):  
MUHAMMAD TARIQ NADEEM ◽  
MAZHAR ABBAS ◽  
TAQI HASSAN ◽  
Shahid Masood
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Recurrent Abdominal Pain ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Endoscopic Findings ◽  
Group A ◽  
H Pylori ◽  
Group B

Objective: To assess the association between the Helicobacter Pylori (H.pylori) infection andrecurrent abdominal pain (RAP) by documenting the frequency of Helicobacter pylori infection in children aged 5 to 15years in our setup. Design: A comparative study. Place and Duration of Study: The study was conducted in pediatricunit Military Hospital Rawalpindi over one year period from 1st Apr 200 to 31st Mar 2002. Subject and Methods: Wedivided the patients into two groups; group A or the study group and the group B or the control group. In group A, atotal of 87 Children aged 5 to 15 years presenting with RAP in which no underlying cause was found on initialassessment underwent upper gastrointestinal tract (GIT) endoscopic examination. In group B (control) we included 68children in whom upper GIT endoscopy was done for any reason other than the RAP. In both the groups thegastroduodenal biopsy samples were sent for culture and histological examination for the diagnosis of H. pyloriinfection. The signs and symptoms of these patients were analyzed in detail. Results: In group A, out of 87 patientswho were endoscoped there were 44 female and 43 male. 54(62%) were found positive and 33(38%) were foundnegative for H.pylori on histopathology and culture examination of biopsy samples. In the control group (B) thefrequency of H.pylori infection was 35% (24 of 68) which was significantly lower than the study group (p-value .001).The frequency of H.pylori increased significantly with advancement in age (p-value .003) and lowering of thesocioeconomic status (p-value.002). The commonest endoscopic finding was antral gastritis (31 of 87; 35.6%). Antralnodularity was observed in 8(26%) out of 36 cases of antral gastritis and in 23(74%) cases there was antral erythemawithout nodularity. The remaining endoscopic findings were pan-gastritis (14 of 87;16%), duodenal ulcer (10 of87;11.5%), duodenitis (4 of 87;4.6%) and gastric ulcer (2 of 87;2.3%). The less frequent findings were gastric andduodenal erosions and esophagitis (about 1% each).Their was no abnormal finding in 22(25.3%) cases. Childrenpredominantly (52%) had the symptoms characteristics of ulcer-like dyspepsia. Recurrent epigastric pain wassignificantly more common in the H.pylori positive than the H. pylori negative children (44 of 87 vs 16 of 33 [p-value.001]). There was no difference for other symptom characteristics when comparing infected with non-infected children.Conclusion: The frequency of H.pylori infection is high in children with recurrent abdominal pain and there is a high degree of association between recurrent abdominal pain, endoscopic findings (chronic gastritis, duodenitis, gastric andduodenal ulcer) and the H. pylori infection.

scholarly journals Association between Helicobacter Pylori and Hyperemesis Gravidarum

2017 ◽  
Vol 8 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Nilofar Yasmin ◽  
Kohinoor Begum ◽  
Santosh Kumar Saha ◽  
Kamrun Naher ◽  
Dilip Kumar Ghosh ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Hyperemesis Gravidarum ◽  
Control Group ◽  
P Value ◽  
Igg Antibody ◽  
College Hospital ◽  
Group A ◽  
H Pylori ◽  
Group B ◽  
In Pregnancy

Background: Hyperemesis gravidarum (HG) is the severe form of the nausea & vomiting in pregnancy and is associated with weight loss, ketonemia ,ketonuria ,electrolyte imbalances and profound volume depletion. Increased accumulation of fluid caused by elevated steroid hormones in pregnancy, a shift in pH and change of pH in the gastrointestinal tract could result in the manifestation of subclinical Helicobacter pylori (H. Pylori) infection. We therefore examined whether seropositivity for IgG antibodies to H. Pylori may be related to hyperemesis graviderum.Objective: To determine the association of H-pylori infection in hyperemesis graviderum patients.Methodology: A cross sectional study was conducted in the department of obstetrics and gynaecology, Dhaka medical college hospital from January 2007 to December 2008. Total 82 pregnant patients, 40 were hyperemesis gravidarum patients (Cases, group A) and 42 were normal pregnancy without hyperemesis graviderum (Control, group B) for admission and attending for routine ANC in OPD were selected. Purposive sampling method was followed as per inclusion and exclusion criteria. Evaluation of the patients was based on history, physical examination and investigation. Serum IgG antibody response to H.pylori antigen by ELISA were measured from every patients and analysed for its association with HG.Results: Most of the patients of this study were primi gravida, Group-A was 72.5% and Group-B was 66.7%. Maximum number of women in both the groups belonged to lower socio-economic status (Group-A was 85% and Group-B was (76%). Previous H/O hyperemesis gravidarum in the Group-A was 52.5% and Group-B was 07 % (p<.01), that is statistically highly significant. Antibody to Helicobactor pylori in serum was positive in Group-A 47.5%, and Group-B 19%. The difference was statistically significant. (p value-0.006).Conclusion: According to the findings of our study, H.pylori infection would seem to be an important associated factor in the exacerbation of HG, but it does not seem to be the only cause of the disease.J Shaheed Suhrawardy Med Coll, June 2016, Vol.8(1); 13-16

scholarly journals The Association between Helicobacter Pylori Infection and Abdominal Pain in Children Aged 2-10 Years

2016 ◽  
Vol 5 (1) ◽  
pp. 19-24
Author(s):  
Dariush Zohoori ◽  
Omid Sadeghi Ardakani
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Demographic Data ◽  
Positive Association ◽  
Recurrent Abdominal Pain ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Case Group ◽  
The Mean ◽  
H Pylori

Background: Helicobacter pylori (H. Pylori) is a common infection in children, especially in the developing countries. The infection is usually asymptomatic but it may cause gastrointestinal diseases. In children, the symptoms include abdominal pain, vomiting and anemia. Recurrent abdominal pain (RAP) is a common cause of children’s referral. But, whether H. Pylori causes RAP in children has to be scrutinized to prevent further complications by proper diagnosis and treatment. However, there is still controversy in the literature regarding this issue. Therefore, we aimed to assess the association between H. Pylori and RAP in children. Materials and Methods: In this case-control study, the children with RAP aged 2-10 years who referred to a private pediatric clinic in Marvdasht, Iran, were compared to other children without RAP, during 2015. The sample size was calculated to be 70 for each case and the control group. The patients were visited by a gastro-enterologist who recorded the demographic data of all the patients and the findings of stool test for H. Pylori. To assess the association of RAP with H. Pylori, the odds ratio was calculated. The statistical analysis was performed using SPSS 20.0 software. The P-values less than 0.05 were considered as statistically significant. Results: The mean age of the participants was 7.35±3.11 (with a range of 2-10). In the case group, 41/70 and 69/70 of the control group were girls. H. Pylori was found positive in 37 cases (52.9%) of the case group and 11 (15.7%) in the control group (P<0.001, OR=6.01, 95% CI=2.71-13.34). Logistic regression with adjustment for age indicated that there was a positive association between positive H. Pylori and abdominal pain (OR=16.69, 95% CI=4.71-59.18). This model also showed that by adjusting the H. Pylori test result, age was also positively associated with abdominal pain (OR=0.27, 95% CI=0.18-0.45). A T-test also indicated that the mean titer of H. Pylori was significantly higher in case group (1.42±1.29) than the control group (0.86±1.52) (P=0.020). Conclusion: There was a statistically significant correlation between H. Pylori and RAP. [GMJ. 2016;5(1):19-24]

scholarly journals Comparison between the Outcome of Tunica Vaginalis Blanket Wrap and Non-wrap Procedures in Urethroplasty

2015 ◽  
Vol 3 (1) ◽  
pp. 30-36
Author(s):  
Mohammad Minhajuddin Sajid ◽  
Md Shahid Karim
Keyword(s):  
Ventral Surface ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Paediatric Surgery ◽  
Tunica Vaginalis ◽  
Total Period ◽  
Rate Of Development ◽  
Group A ◽  
Group B

Background: Hypospadias is a developmental anomaly characterized by a urethral meatus that opens onto the ventral surface of the penis, proximal to the end of glans. Fistulas are the most common complication following hypospadias repairs. This study was carried out to see that application of vascularized Tunica Vaginalis Blanket Wrap (TVBW) in urethroplasty reduces fistula rate in hypospadias repair. Objectives: To study the efficacy of Tunica vaginalis blanket wrap to prevent urethrocutaneous (UC) fistula in urethroplasty for hypospadias repair.Methods:Study Design : Prospective comparative studyPlace of Study :Department of Paediatric surgery, Dhaka Shishu Hospital (DSH), Dhaka.Period of Study :April, 2003 to October, 2004 for a total period of 19 months.The study of population : Twenty (20) admitted patients of hypospadias were selected. Patients were grouped into group A and group B on the basis of lottery method. Group A included 10 cases, who were subjected to repair of hypospadias with the application TVBW. Group B included 10 cases, who were subjected to repair of hypospadias without TVBW.Statistical Analysis : Chi-square test (X2 test) were applied. p value <0.01 was taken as significant.Ethical aspect : Research protocol was accepted by DSH. Written consent were taken from parents.Result: Occurrence of post operated UC fistula found significantly higher in non TVBW. Discussion: In our patients for group A (study group), TVBW was used in urethroplasty while urethroplasty for group B (control group) was carried out without TVBW. UC fistula was present in 1 patient (10%) in group A post operatively and in 5 patients (50%) in group B postoperatively and subsequently 2 more patients developed fistula during follow up period. In control group 7 patient (70%) developed UC fistula out of 10 patients (n=10) despite of using periurethral flap of tissue as second layer over the neourethra. In our study, the rate of development of UC fistula is much less (only 10%) in study group. So the result is significant as evidenced by p value which is less than <0.01.This study demonstrates that use of tunica vaginalis as a blanket wrap as second layer over the neourethra reduces the rate of development of UC fistula.Conclusion: TVBW is recommended for urethroplasty to decrease the postoperative UC fistula.J. Paediatr. Surg. Bangladesh 3(1): 30-36, 2012 (January)

Helicobacter Pylori Infection in Sjögren’s Syndrome: Co-incidence or Causality?

2019 ◽  
Vol 15 (3) ◽  
pp. 238-241
Author(s):  
Massoud Saghafi ◽  
Nafiseh Abdolahi ◽  
Reza Orang ◽  
Mohammad Reza Hatef ◽  
Mohammad Hadi Molseghi
Keyword(s):  
Helicobacter Pylori ◽  
Serum Level ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Control Group ◽  
P Value ◽  
H Pylori ◽  
Sjögren‘S Syndrome

Background and Aim: Lymphoid cell infiltration and destruction of exocrine glands, specifically lacrimal and salivary glands are characteristics of Sjogren’s syndrome (SS). An etiological role has been proposed for Helicobacter pylori (H. pylori), interacting in the clinical course and complications of SS (including gastric cancer and lymphoma). The aim of this study was to identify the probable correlation between H. pylori infection and Sjogren’s syndrome (SS). Methods: In this case-control study, ELISA method was used to determine serum level of IgA and IgM anti H. pylori antibody in 43 subjects with SS according to the international criteria and 95 healthy subjects as control. SPSS-17 was used to analyze data with t-test. P value <.05 were considered significant. Results: Serum level of IgM (34.9% vs. 10.5%, p-value= 0.001) and IgA (67.4% vs. 46.3% p value= 0.021) anti H. pylori antibody were significantly higher in SS patients compared to the control group. There was a positive correlation between age and H. pylori infection (r=0.2, Pvalue= 0.05). Conclusion: Patients with SS had a higher prevalence of H. pylori infection compared to the normal population. Eradication of H. pylori is recommended particularly in older patients with SS.

Moxifloxacin Based Triple Therapy as Alternative to Standard Therapy in Helicobacter Pylori Eradication.

2020 ◽  
Vol 18 ◽  
Author(s):  
Mohammed Hussien Ahmed ◽  
Sherief Abd-Elsalam ◽  
Aya Mohammed Mahrous
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Therapy Group ◽  
Low Cost ◽  
High Rate ◽  
Helicobacter Pylori Eradication ◽  
Treatment Regimens ◽  
Group A ◽  
H Pylori ◽  
Group B

Introduction: Helicobacter pylori eradication remains a problematic issue. We are in an urgent need for finding a treatment regimen that achieves eradication at a low cost and less side effect. Recent published results showing a high rate of resistance and with clarithromycin-based treatment regimens. The aim of the study was to compare moxifloxacin therapy and classic clarithromycin triple therapy in H. pylori eradication. Methods: This was a pilot study that enrolled 60 patients with helicobacter pylori associated gastritis. Diagnosis was done by assessment of H. pylori Ag in the stool. The patients were randomly assigned to receive either moxifloxacin based therapy (Group A), or clarithromycin based therapy (Group B) for two weeks. We stopped the treatment for another two weeks then reevaluation for cure was done. Results: 90 % of patients had negative H. pylori Ag in the stool after 2 weeks of stoppage of the treatment in group A versus 66.7 % in Group B. None of the patients in both groups had major side effects. Conclusion: Moxifloxacin-based therapy showed higher eradication power and less resistance when compared to clarithromycin triple therapy.

Does laryngopharyngeal reflux affect healing and recovery after tonsillectomy?

2007 ◽  
Vol 122 (6) ◽  
pp. 603-608 ◽  
Author(s):  
S Elwany ◽  
Y A Nour ◽  
E A Magdy
Keyword(s):  
Wound Healing ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Control Group ◽  
Study Group ◽  
Pain Scores ◽  
Blinded Study ◽  
Group A ◽  
Group B ◽  
Control Group Group

AbstractIntroduction:Laryngopharyngeal reflux is increasingly being implicated in several otolaryngological disorders.Aims:To study a potential correlation between pre-operative laryngopharyngeal reflux and wound healing and recovery after tonsillectomy, based on subjective and objective findings.Materials and methods:A prospective, blinded study was undertaken, including 60 patients scheduled for tonsillectomy, divided into two equal groups: a study group (group A) with pre-operative laryngopharyngeal reflux documented using ambulatory 24-hour pH monitoring; and a control group (group B) without laryngopharyngeal reflux.Results:Group A had significantly higher pain scores on the seventh and 14th post-operative days (p = 0.022 and p = 0.000, respectively) and took a significantly longer time to return to normal eating (p = 0.013), compared with group B. Group A also showed significantly slower healing on the seventh and 14th post-operative days, as estimated by assessing the grade of post-operative slough formation (p = 0.016 and p = 0.029, respectively). A significant correlation between the number of pharyngeal reflux episodes and the degree of post-operative slough was also found.Conclusions:Laryngopharyngeal reflux can significantly decrease wound healing following tonsillectomy. Therefore, pre-operative recognition and management of this condition is desirable in order to eliminate its negative post-operative effect.

scholarly journals Effect of acupuncture TENS versus conventional TENS on post cesarean section incision pain

2018 ◽  
Vol 7 (9) ◽  
pp. 3738
Author(s):  
Priti A. Mehendale ◽  
Mayur T. Revadkar
Keyword(s):  
Pain Intensity ◽  
Rating Scale ◽  
Control Group ◽  
P Value ◽  
Random Allocation ◽  
Lower Segment Caesarean Section ◽  
Post Operative Pain ◽  
Group A ◽  
Group B ◽  
Pain Rating Scale

Background: There is evidence regarding beneficial use of Transcutaneous Electrical Nerve Stimulation (TENS) on post Lower Segment Caesarean Section (LSCS) incision pain. However, efficacy of different types of TENS following C section pain has not yet been explored adequately.Methods: 96 women who had recently undergone LSCS were included for the study. The subjects were in the age group of 20 to 40 years (25.84±3.96); having pain intensity 4 or more on Numerical Pain Rating Scale (NPRS). They were divided into three groups by random allocation method; namely Group A: Acupuncture (Low/Motor) TENS, Group B: Conventional (High/Sensory) TENS and Group C: Control group. Group A and B received specific type of TENS twice a day for 15 minutes. Control group C did not receive any TENS intervention. All subjects received standard post-operative medications and physiotherapy. Pain intensity was recorded on NPRS pre and post intervention.Results: Both Acupuncture TENS and Conventional TENS significantly decreased post-operative pain intensity as compared to control group (p value <0.0001).Conclusions: Both, acupuncture and conventional TENS are equally effective in reducing post LSCS incision pain at a strong and non-painful intensity.

scholarly journals Effects of Aqueous Extract of Basella alba L. leaves on Blood Cell Count in Rats

2019 ◽  
Vol 22 (1) ◽  
pp. 73-78
Author(s):  
Farhana Sabrin ◽  
AF Mohammed Shafiqul Alam ◽  
Muhammad Rashedul Islam ◽  
Md Elias Al Mamun ◽  
Jakir Ahmed Chowdhury
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Aqueous Extract ◽  
Control Group ◽  
P Value ◽  
Blood Cell Count ◽  
Basella Alba ◽  
Group A ◽  
Group B ◽  
Group D

The effect of aqueous extract of Basella alba (puishak) leaves on blood cell count of rats was studied. Forty rats of both sexes weighing between 100-150 gm were used. The rats were divided into four groups (7 rats in each group), with group A as the control group and experimental groups were denoted as B, C and D. With all aseptic precautions, aqueous extract of Basella alba (Puishak) leaves was administered into the three different doses (For group B: 60 mg/kg bw, group C: 80 mg/kg bw and group D: 100 mg/kg bw). Control group A also received distilled water as a placebo at the dose of 10 mg/kg bw for 14 days. At day 15, blood samples were collected and sent for haematological analysis. Data analysis of blood count profile of 28 rats revealed that there is an increased number of RBC, WBC and platelet count in experimental groups than in control group. ANOVA test revealed that increased blood cell counts following administration of aqueous leaves extract of keeves of B. alba were statistically significant (p value for each case was .0001<.05) than control group. Paired samples t test was performed to compare between baseline hematological parameters and parameters after 14 days of intervention. Then comparison between Group A & Group B, between Group A & Group C and between Group A & Group D were done. In all cases, probability (p) value < 0.05 was considered as statistically significant.This it is clearly evident that aqueous extract of B.alba has positive stimulant effect on blood cells count of rats. Moreover, it was found that increment of doses also increases the cell count that is positively correlated with the hypothesis. Bangladesh Pharmaceutical Journal 22(1): 73-78, 2019

scholarly journals Helicobacter pylori associated with breastfeeding, nutritional status and recurrent abdominal pain in healthy Nigerian children

2014 ◽  
Vol 8 (04) ◽  
pp. 448-453 ◽  
Author(s):  
Idowu O Senbanjo ◽  
Kazeem A Oshikoya ◽  
Olisamedua F Njokanma
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Nutritional Status ◽  
Recurrent Abdominal Pain ◽  
University Teaching ◽  
Breastfeeding Duration ◽  
Pediatric Care ◽  
Enzyme Linked Immunosorbent Assay ◽  
Healthy Children ◽  
H Pylori

Introduction: There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a group of apparently healthy children and adolescents in Lagos, Nigeria. Methodology: This was a prospective hospital-based study conducted at the Lagos State University Teaching Hospital that involved 118 children who came to the hospital for routine pediatric care. Seroprevalence status of the children was determined by measuring immunoglobulin G antibodies against H. pylori using enzyme-linked immunosorbent assay (ELISA). Results: Seventy-five (63.6%) children were seropositive for H. pylori. The prevalence of H. pylori infection increased significantly from 40.4% in children less than five years of age to 85.1% at six to ten years of age (χ2 = 20.9, p < 0.001). H. pylori infection was associated with low social class (OR = 3.24; 95% CI = 1.20-8.23, p = 0.016) and with RAP (OR = 3.47; 95% CI = 1.55-7.79, p = 0.002), but no association was observed with exclusive breastfeeding, duration of breastfeeding, and under-nutrition. Conclusions: The prevalence of H. pylori infection is high, particularly among children from low socioeconomic backgrounds in Lagos, Nigeria. It is associated with RAP. The effect of this infection on children’s health requires further studies.

scholarly journals Efficacy of Tamsulosin and Alfuzosin in Management of Distal Ureteral Stones

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 10-13
Author(s):  
Bimochan Piya ◽  
Abhishek Bhattarai
Keyword(s):  
Urinary Tract ◽  
Side Effects ◽  
Diclofenac Sodium ◽  
Study Groups ◽  
Ureteral Stones ◽  
Control Group ◽  
P Value ◽  
Expulsion Rate ◽  
Group A ◽  
Group B

Introduction: Urinary tract calculi are the most frequent condition in urology clinics worldwide. The overall prevalence is about 5 % and lower urinary tract stones account for 70% among them. Medical expulsive therapy has been used to treat distal ureteric stone as it reduces symptoms and facilitates stone expulsion. The aim of this study is to evaluate and compare the efficacy of tamsulosin and alfuzosin as medical therapy in ureteric stones. Materials and Methods: A total of 87 patients with distal ureteral stones of size ≤10 mm were randomly divided into 3 groups. Group A patients (n-30) received 0.4 mg of tamsulosin daily, group B patients (n-29) received 10 mg of alfuzosin daily and group C patients (n-28) received 75 mg of diclofenac sodium. Patients in all groups received diclofenac sodium for one week and then as required. Follow-up was done on a weekly basis for 4 weeks. The stone expulsion rate, time for stone expulsion, and side-effects were recorded in each group. Results: The mean stone size (5.66, 5.79, 5.67) mm and age (29.1, 30.31, 29.4) were comparable in each group. The stone expulsion rate was 83.3%, 79.3%, and 50% in groups A, B, and C respectively.  It showed that both the study groups (Group A and Group B) were effective than the control group (p-value 0.006 and 0.02 respectively) but there was no difference between tamsulosin and alfuzosin (p-value 0.69). The duration of stone expulsion was 11.5 days, 11.8 days, and 17.3 days for Group A, B, and C respectively. The drugs related side effects reported by patients were mild and transient. Conclusion:  The use of tamsulosin and alfuzosin for the medical treatment of ureteric stones proved to be safe and effective and neither did have any significant benefits over the other.

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