The Effects of Ramadan Fasting on Certain Biochemical Parameters in Normal Subjects and in Type II Diabetic Patients

1994 ◽  
Vol 14 (2) ◽  
pp. 139-141 ◽  
Author(s):  
Abdel Fattah A. Al-Hader ◽  
Niazy A. Abu-Farsakh ◽  
Said Y. Khatib ◽  
Zuheir A. Hasan
2006 ◽  
Vol 110 (4) ◽  
pp. 467-473 ◽  
Author(s):  
Per Lav Madsen ◽  
Michaela Scheuermann Freestone ◽  
Stefan Neubauer ◽  
Keith Channon ◽  
Kieran Clarke

A low [Hb] (Hb concentration) is out-balanced by peripheral vasodilation via mechanisms that are incompletely understood. Peripheral vasodilation is influenced by NO (nitric oxide) released from vascular endothelium in response to increased vessel wall shear stress, and absorption by Hb is the main mechanism by which the bioactivity of NO is disarmed. Thus we propose that graded NO absorption is the mechanism through which a low [Hb] is related to peripheral vasodilation. In the present study, we examined the relationship between [Hb] and FMD (flow-mediated vasodilation; 5 min of cuff ischaemia) of the radial and brachial arteries in 33 normal subjects and in 13 patients with Type II diabetes, known to have impaired NO-mediated vasodilation. The smaller radial artery provided the more sensitive test, as it had a 2-fold larger FMD than the brachial artery (22±18% compared with 9±18% respectively, in normal subjects; means±S.D., P<0.05). FMD of the radial artery had a negative correlation with [Hb] (r2=−0.66, P<0.05; n=27). In subjects with [Hb] below and above the median of 14.1 g/dl, the radial artery FMD was 30±22% compared with 13±12% respectively (P<0.05). In diabetic patients, FMD was lower and a co-variation with [Hb] could not be established. Thus, in normal subjects, NO-mediated endothelium-related vasodilation at least partly out-balanced the ‘added burden’ of a low [Hb] during post-ischaemic reperfusion.


1991 ◽  
Vol 11 (2-3) ◽  
pp. 261-264 ◽  
Author(s):  
Riad A. Sulimani ◽  
Mohammed Laajam ◽  
Omar Al-Attas ◽  
Funsho O. Famuyiwa ◽  
Sami Bashi ◽  
...  

2014 ◽  
Vol 11 (2) ◽  
pp. 317-330
Author(s):  
Baghdad Science Journal

This study included effect of polyherbs mixture treatment of diabetic patients type II for two months. The polyherbs mixture contains Nigella sativa seeds, Boswellia carterri gum, Citrus aurantifolia fruits, Elettaria cardamomum fruits. Also this study included estimation of some biochemical parameters in the serum Diabetes Mellitus (D.M.) patients-type II and knowing the relationship of these parameters with this disease. The parameters are glucose, cholesterol ,High density , Low density lipoproteins( HDL-C, LDL-C) respectively , Triglycerides TG, urea, total protein , albumin , Alkaline phosphatase ALP,Transaminase GOT, GPT enzymes . Take (77) samples of diabetic patients serum type II which included (47) samples for group one: herbs + chemical treatment (drugs), (30) samples for group two: herbs only which were compared with (30) samples from health person as control group. From this study, the results shows that is an increase in the value of the following parameters such as glucose, cholesterol, LDL-C, TG, urea, and enzyme ALP, GOT and GPT in blood before the treatment of patients with herbs and decreasing of these values after treatment with herbs for both one & two months , but an increasing was noticed when the treatment of these patients was stopped. At the same time, the results shows a decrease in HDL-C, total protein, albumin values before treatment with herbs of these patients and an increasing after treatment but decreasing was noticed at stopping of the treatment. On the other hands, these results observed the level of cholesterol for second group of patients after treatment with polyherbs for first and second month return to normal level and LDL-C level of the two groups of patients and increasing of these levels after stopped the treatment for one month to a value approximately to the value before treatment of these patients. Also observed the levels of total protein, albumin reached to normal levels of these parameters for the second group of patients treatment at second month.


2019 ◽  
Vol 150 (6) ◽  
pp. 546 ◽  
Author(s):  
Seval Kul ◽  
Neriman Aydın ◽  
Gülendam Karadağ ◽  
Suzan Tabur ◽  
Mustafa Araz

Author(s):  
Dr. Agnihotri Bhattacharyya ◽  
Dr. Kaushik Kar

Introduction: The diagnostic parameters of diabetes in obese and non obese individuals might not be always same because the physiological basis of developing diabetes in them is not similar. Objectives: The present study has been done to assess any significant difference in the Clinical and Biochemical parameters of diabetes like Glycosylated Haemoglobin (HbA1C), Fasting and Post prandial Blood Sugar (FBS and PPBS) among obese and non obese Type II Diabetes patients. Methodology: The present study was undertaken in the Medicine Outdoor of Calcutta National Medical College during June to August 2018 among 100 Type II Diabetes Mellitus patients of both sexes and aged 18 or above prior to an informed consent. Any significant difference in the Clinical and Biochemical parameters of diabetes among different groups of Diabetic patients as per BMI and waist circumference was assessed. Data was analyzed by standard statistical software like SPSS version 20 with proportion and percentage and using parametric and non-parametric tests like Chi-squares and ANNOVA. Result: The study reveals that 30% of the study population has BMI 25-29.99 kg/m2, 9% has 30-34.99 kg/m2 and 3% have BMI between 35-39.99 kg/m2 and 83.67% of Males and 96.07% of females have increased Waist Circumference Complications like Diabetic Nephropathy, Retinopathy, Neuropathy and Foot ulcer etc was found in 61% of the study population. There is significant difference in mean values of Glycosylated Haemoglobin, fasting blood sugar and post prandial blood sugar in the different groups of BMI. 32.78% of patients with complications of Diabetes Mellitus have BMI>24.99 and this association is statistically significant. Conclusion: The present study has found significant difference of the mean values of diagnostic parameters of diabetes in different groups according to Body Mass Index.  However the study was performed with the population who were already on treatment for some duration, so there can be a variation of findings in the present study from other studies done in different settings like primary care hospitals or with patients at onset of diabetes. Key words: Diabetes, Glycosylated Haemoglobin, Fasting blood sugar, Post prandial blood sugar


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