scholarly journals GENETIC AND DIURNAL VARIATIONS IN THE SERUM PROTEIN PROFILE OF YEARLING CAPRINE MALES

2021 ◽  
Vol 6 ◽  
pp. 33-37
Author(s):  
G. N. Ogbunike ◽  
L. H. Jeyakuma ◽  
T. U. Obi
Keyword(s):  
Serum Protein ◽  
Serum Proteins ◽  
Protein Profile ◽  
West African ◽  
Diurnal Variations ◽  
Total Serum ◽  
The West ◽  
West African Dwarf ◽  
Susceptibility To Infection ◽  
Serum Protein Profile

12 GOATS comprising 4 of each of three breeds, namely West African Dwarf, Red Sokoto and crossbreds (West African Dwarf x Saanen), were bled alternately in the mornings and afternoons to evaluate their serum protein profile. The three breeds were similar in total serum proteins but not in protein profile. The crossbred goats had more albumin than the purebreds. Alpha and beta globulins occurred in equal proportions in the West African Dwarf and crossbred goats although the latter were extremely low in gamma globulins. The results imply a higher growth rate and susceptibility to infection of the crossbred goats and suggest the need for greater husbandry care by them.

scholarly journals Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Victor Farutin ◽  
Elma Kurtagic ◽  
Joël R. Pradines ◽  
Ishan Capila ◽  
Maureen D. Mayes ◽  
...  
Keyword(s):  
Gene Expression ◽  
Comparative Analysis ◽  
Systemic Sclerosis ◽  
Differential Expression ◽  
Serum Protein ◽  
Peripheral Blood ◽  
Serum Proteins ◽  
Protein Profile ◽  
Organ Level ◽  
Serum Protein Profile

Abstract Background Serum proteins can be readily assessed during routine clinical care. However, it is unclear to what extent serum proteins reflect the molecular dysregulations of peripheral blood cells (PBCs) or affected end-organs in systemic sclerosis (SSc). We conducted a multiomic comparative analysis of SSc serum profile, PBC, and skin gene expression in concurrently collected samples. Methods Global gene expression profiling was carried out in skin and PBC samples obtained from 49 SSc patients enrolled in the GENISOS observational cohort and 25 unaffected controls. Levels of 911 proteins were determined by Olink Proximity Extension Assay in concurrently collected serum samples. Results Both SSc PBC and skin transcriptomes showed a prominent type I interferon signature. The examination of SSc serum profile revealed an upregulation of proteins involved in pro-fibrotic homing and extravasation, as well as extracellular matrix components/modulators. Notably, several soluble receptor proteins such as EGFR, ERBB2, ERBB3, VEGFR2, TGFBR3, and PDGF-Rα were downregulated. Thirty-nine proteins correlated with severity of SSc skin disease. The differential expression of serum protein in SSc vs. control comparison significantly correlated with the differential expression of corresponding transcripts in skin but not in PBCs. Moreover, the differentially expressed serum proteins were significantly more connected to the Well-Associated-Proteins in the skin than PBC gene expression dataset. The assessment of the concordance of between-sample similarities revealed that the molecular profile of serum proteins and skin gene expression data were significantly concordant in patients with SSc but not in healthy controls. Conclusions SSc serum protein profile shows an upregulation of profibrotic cytokines and a downregulation of soluble EGF and other key receptors. Our multilevel comparative analysis indicates that the serum protein profile in SSc correlates more closely with molecular dysregulations of skin than PBCs and might serve as a reflection of disease severity at the end-organ level.

scholarly journals Detection of Papillary Thyroid Carcinoma With Serum Protein Profile Analysis

2008 ◽  
Vol 134 (2) ◽  
pp. 198 ◽  
Author(s):  
William H. Moretz ◽  
Christine G. Gourin ◽  
David J. Terris ◽  
Zhong-Sheng Xia ◽  
Zhongmin Liu ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Serum Protein ◽  
Profile Analysis ◽  
Protein Profile ◽  
Papillary Thyroid ◽  
Serum Protein Profile

Muscle Weight Relationship to Serum Proteins, Hemocytes, and Hepatopancreas in the Lobster, Homarus americanus

1967 ◽  
Vol 24 (11) ◽  
pp. 2339-2354 ◽  
Author(s):  
James E. Stewart ◽  
John W. Cornick ◽  
Diane M. Foley ◽  
M. F. Li ◽  
C. M. Bishop
Keyword(s):  
Serum Protein ◽  
Physiological Condition ◽  
Serum Proteins ◽  
Homarus Americanus ◽  
Total Serum Protein ◽  
Total Serum ◽  
Experimental Conditions ◽  
Muscle Weight ◽  
Beef Liver ◽  
The Relationship

Total serum protein values, hemocyte numbers, and muscle weights were determined for 216 intermolt lobsters immediately after their capture, and for 230 others held captive under a variety of dietary and environmental conditions. Average muscle values ranged from approximately 13% to the more normal 20–25% of the live animals' weight, depending upon experimental conditions. The total serum protein up to a level of 55 mg/ml was shown to be a reliable indicator of muscle weights, although the relationship was not identical for all lobster groups. It appeared to be modified chiefly by the areas from which the different groups were taken. Diet was more important than the temperatures (5 to 14 C) in affecting changes in muscle and serum protein values. Starvation caused a greater reduction (50 to 70%) in the size of the hepatopancreas than in the muscle. Histological examination of the hepatopancreatic tissue showed that the lipid content was markedly reduced upon starvation and that a degeneration of this organ was apparent for lobsters fed a beef liver and herring diet. Measurement of serum proteins would appear to be a useful technique in experiments on lobster nutrition and have value, within specified limits, for assessing the physiological condition of wild lobsters.

scholarly journals Serum Protein Profile at Remission Can Accurately Assess Therapeutic Outcomes and Survival for Serous Ovarian Cancer

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e78393 ◽  
Author(s):  
Jinhua Wang ◽  
Ashok Sharma ◽  
Sharad A. Ghamande ◽  
Stephen Bush ◽  
Daron Ferris ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Serum Protein ◽  
Protein Profile ◽  
Serous Ovarian Cancer ◽  
Therapeutic Outcomes ◽  
Serum Protein Profile

scholarly journals Serum Protein Profile Of Iraqi Hydatidosis Patients with Different Sites of Infection

2007 ◽  
Vol 4 (4) ◽  
pp. 612-616
Author(s):  
Baghdad Science Journal
Keyword(s):  
Serum Protein ◽  
Protein Profile ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Healthy Individuals ◽  
Banding Patterns ◽  
Blood Samples ◽  
Molecular Weights ◽  
Serum Protein Profile

Blood samples of One hundred and twenty patients from different hospitals in Baghdad infected with hydatidosis in different sites of the body (Liver, Lung, multiorgans and kidney) were collected for this study. On the other hand, 30 healthy individuals were included as a control group. This study was conducted to evaluate the effect of this disease on the serum protein profile of the patients using electrophoresis. The results revealed four different protein banding patterns with difference in number of bands and their molecular weights in comparison to the control group, and these differences depended on the site of infection. However the data showed a presence of the same band in all patients with different site of infection.

AB070. P042. Serum protein profile in IPMN

2018 ◽  
Vol 1 (1) ◽  
pp. AB070-AB070
Author(s):  
Hanna Seppanen ◽  
Heini Nieminen ◽  
Mayank Saraswat ◽  
Sakari Joenväärä ◽  
Ari Ristimäki ◽  
...  
Keyword(s):  
Serum Protein ◽  
Protein Profile ◽  
Serum Protein Profile
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