STUDY THE ISOLATION RATE AND ANTIBIOTIC RESISTANCE OF ACINETOBACTER SPP IN THE INTENSIVE CARE DEPARTMENT THANH NHAN HOSPITAL

2021 ◽  
Vol 62 (6) ◽  
Author(s):  
Nguyen Thi Loan ◽  
La Thi Huyen ◽  
Nguyen Minh Hien
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Cross Section ◽  
Isolation Rate ◽  
Intensive Care Department ◽  
Acinetobacter Spp ◽  
Hospital Acquired ◽  
High Degree ◽  
Respiratory Specimens

Objectives: To describe the isolation rate and antibiotic status of Acinetobacter ssp hospital-acquired bacteria in the intensive care unit. Methods: 1434 patient samples isolated patient samples, cultured, performed antibiogram, described cross-section. Results: 109/331 strains of Acinetobacter spp were isolated (32.9%) and mainly from respiratory specimens, catheters (76.1% and 14.7%). Acinetobacter spp has a high degree of antibiotic resistance to most of the antibiotics Ceftazidime: 91.7%, Cefepime 91.7%, gentamycine 91.7%, Amikacin 83.3%, Imipenem and Meropenem 75%, still sensitive 100 % with antibiotics Polimycin B and Colistin.

Antibiotic Resistance for Common Hospital Acquired-pneumonia Pathogens in the Intensive Care Unit of Newly Opened Hospital

2002 ◽  
Vol 52 (3) ◽  
pp. 207 ◽  
Author(s):  
Jae Hyung Lee ◽  
Sung Joon Shin ◽  
Young Chan Kim ◽  
Seung Il Oh ◽  
Mi Ok Kim ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

scholarly journals Monitoring the antibiotic resistance in the intensive care unit of a multidisciplinary hospital

2018 ◽  
Vol 10 (4) ◽  
pp. 284-297
Author(s):  
V. Yu. Zemko ◽  
V. K. Okulich ◽  
A. M. Dzyadz’ko
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Organ Transplantation ◽  
Antibacterial Therapy ◽  
Infectious Complications ◽  
Clinical Hospital ◽  
Therapy Initiation ◽  
Study Results ◽  
Acinetobacter Spp

Background. Infectious complications remain a serious post-transplant problem and make a major cause of poor outcome. Given the active development of transplant services at a regional level, the problem of infectious complications becomes increasingly important and requires monitoring of the etiological structure and level of antibiotic resistance in each hospital dealing with this problem.The purpose was to analyze the changes over time in the structure and antimicrobial resistance of the most common pathogens in various nosology, including in patients after organ transplantation, regardless gender and age.Material and methods. The study included 37,103 patients, of whom 8,091 (21.8%) were treated in the Intensive Care Unit (ICU) of the Vitebsk Regional Clinical Hospital (VRCH) for the period from 2015 to 2017; infectious complications after organ transplantation made 3%. The clinical samples were studied for bacteriology in the Republican Scientific and Practical Center "Infection in Surgery"; 20,280 clinical isolates were investigated.Results. Staphylococcus aureus (20.96%) dominated in the general structure of microorganisms cultured mainly from the wound surface in thermal burns; meanwhile, in the ICU, gram-negative microflora dominated and was presented with Acinetobacter spp. (22.75%) and Pseudomonas aeruginosa (22.74%) in the majority of cases. By 2017, there had been an increase in resistant isolates of Klebsiella spp. (22.87%) and Acinetobacter spp. (23.09%) and a reduction of P. aeruginosa (13.31%) and S. aureus (18.88%) seeding. The protocol of the antibacterial therapy initiation was set up in the ICU of Vitebsk Regional Clinical Hospital, based on the obtained results demonstrating that all S. aureus isolates were sensitive to linezolid, vancomycin and teicoplanin, while P. aeruginosa was sensitive to colistin. All isolated Acinetobacter spp. were sensitive to colistin and 80% of the isolates were sensitive to sulbactam. More than 95% of K. pneumonia isolates were sensitive to colistin and tigecycline.Conclusion. The current epidemiology is characterized by the prevalence of S. aureus (20.96%) in the overall structure of microorganisms, while Acinetobacter spp. (22.25%) and P. aeruginosa (22.74%) dominate in the ICU. Based on the microbiology study results, the protocol of antibacterial therapy initiation was established in the ICU of Vitebsk Regional Clinical Hospital. It is necessary to monitor the resistance of common microorganisms to certain antibiotics in order to develop algorithms for rational antibacterial treatment in each hospital.

scholarly journals Multi-Drug Resistant Bacteria as Aetiological Factors of Infections in a Tertiary Multidisciplinary Hospital in Poland

Antibiotics ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1232
Author(s):  
Sławomir Poletajew ◽  
Katarzyna Pawlik ◽  
Anna Bonder-Nowicka ◽  
Artur Pakuszewski ◽  
Łukasz Nyk ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Bacterial Infections ◽  
Hospitalized Patients ◽  
Common Mechanism ◽  
Resistant Bacteria ◽  
Hospital Acquired ◽  
Klebsiella Spp

Global and local initiatives were recently undertaken to reduce the burden of antibiotic resistance. The aim of the study was to describe the incidence and the aetiology of bacterial infections among hospitalized patients with special attention paid to the multidrug resistant (MDR) bacteria. This retrospective study was based on prospectively collected data from 150,529 consecutive patients hospitalized in a tertiary multidisciplinary hospital in the years 2017–2019. All consecutive microbiological tests from any biological material performed in the analyzed period were included. Microbiological screening tests (n = 10,677) were excluded. The analysis was focused on aetiological factors of bacterial infections, especially the incidence of MDR bacteria and mechanisms of antibiotic resistance. There were 58,789 microbiological tests performed in the analyzed period. The highest testing rate was noticed for intensive care unit (mean of 3.1 tests per one patient), followed by neonatal intensive care unit (2.7), internal medicine (1.9), pediatrics (1.8), and urology (1.2). Among 58,789 tests, 7690 (13.1%) were positive. MDR bacteria were responsible for 1783 infections (23.2%). The most common antibiotic resistance mechanism reported was ESBL production by Klebsiella spp. or Escherichia coli or Enterobacter spp. isolates (47.3% of all MDR cases). ESBL cases were followed by MRSA (14.7%), VRE (14.2%) and MBL producing Klebsiella spp. (5.6%). Among all infections caused by MDR bacteria, 1175 (65.9%) were diagnosed after 72 h of hospitalization (hospital-acquired infections). Apart from AmpC and ESBL producing Escherichia coli, all MDR bacteria were significantly more common in hospital-acquired infection. MDR bacteria are aetiological factors of a significant portion of infections in hospitalized patients with no remarkable change in the incidence in recent years. Production of ESBL is the most common mechanism of antibiotic resistance and should be regarded as one of the most urgent problems in clinical microbiology.

scholarly journals Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

2015 ◽  
Vol 25 (2) ◽  
pp. 47-51 ◽  
Author(s):  
Quazi Tarikul Islam ◽  
Md Mahmudur Rahman Siddiqui ◽  
Farhana Raz ◽  
Mohammad Asrafuzzaman ◽  
Md Robed Amin
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Tracheal Aspirate ◽  
College Hospital ◽  
Icu Patients ◽  
Gram Negative ◽  
Pseudomonas Spp ◽  
Medical College ◽  
Acinetobacter Spp ◽  
Klebsiella Spp

Because of importance of Hospital acquired infections (HAIs), it is critical to conduct surveillance studies to obtain the required data about the regional microorganisms and their susceptibility to antibiotics. This study to investigate antimicrobial resistance pattern among Intensive Care Unit (ICU) patients in a private medical college hospital setup. In a cross sectional study, 100 specimens from patients admitted in the ICU who had signs or symptoms of nosocomial infection were collected from 2012 - 2013. For each patient, samples of blood, urine, tracheal aspirate, sputum, wound swab, pus, and endotracheal tubes were obtained, cultured and analyzed with antibiogram. The most common primary diagnosis were aspiration pneumonia (49%) and UTI (20%) respectively. The most common locations for infection were tracheal aspirate (54%). The most frequent gram negative microorganisms derived from samples were Acinetobacter spp (29%), Klebsiella spp (26%) and Pseudomonas spp (18%). Klebsiella spp, Acinetobacter spp and Pseudomonas spp were most common resistant organisms among all. Klebsiella spp were resistant against Ceftriaxone (84.6%), Ceftazidime (82.6%), Amikacin (46.1%), Gentamicin (66.6%) and Quinolones (65-66.6%) respectively. Acinetobacter spp were resistant against Ceftriaxone (85%), Ceftazidime (88.8%), Cefotaxime (85.7%), Meropenem (79.3%),Amikacin (86.2%), Gentamicin (84.5%) and Quinolons (86.2-89.2%) respectively. Pseudomonas spp were resistant against Ceftriaxone (70.5%), Ceftazidime (66.6%), Amikacin (68.7%), Gentamicin (58.8%), Meropenem (52.9%) and Quinolones (81.2-86.6%) respectively. Meropenem was the most sensitive antibiotic against Klebsiella spp (84.6%) but Cotrimoxazole in case of Acinetobacter spp (60%) respectively. Escherichia coli were mostly isolated from urine, which was sensitive to Amikacin (73.3%) and Meropenem (86.6%) respectively. Gram-negative pathogens obtained from ICU patients in our settings show high resistance to antibiotics. Regular monitoring of the pattern of resistance of common pathogens in the ICUs is essential to up-to-date the use of rational antibiotics regiments.Bangladesh J Medicine Jul 2014; 25 (2) : 47-51

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