scholarly journals TERAPI STIMULASI KOGNITIF UNTUK LANSIA DENGAN MILD COGNITIVE IMPAIRMENT: STUDI EKSPERIMENTAL DI PANTI WREDA

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Nathalie Sanchia ◽  
Magdalena Surjaningsih Halim
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
The Elderly ◽  
Cognitive Stimulation ◽  
Control Group ◽  
Trail Making Test ◽  
Not Given ◽  
Cognitive Stimulation Therapy ◽  
Trail Making

 COGNITIVE STIMULATION THERAPY FOR ELDERLY WITH MILD COGNITIVE IMPAIRMENT: AN EXPERIMENTAL STUDY IN NURSING HOMEABSTRACTIntroduction: Mild cognitive impairment (MCI) is a transitional stage between the elderly’s normal (expected) cognitive decline and the more serious decline caused by dementia that needs interventions. One of the non-pharmacological interventions that can be done is cognitive stimulation therapy (CST). Research has shown that CST can stabilize and/ improve cognitive function in the elderly with MCI.Aims: To find out the differences in cognitive functions in the elderly with MCI and given CST intervention and elderly with MCI not given CST intervention.Methods: This was an experimental study that included elderly aged 60 years old divided into experimental and control group, each consists of four subjects. The experimental group was given CST twice a week with a total of fifteen meetings, but not on the control group. All subjects were subjected to cognitive examinations using neuropsychological instruments before, after, and one month after CST was completed. The statistical analysis performed in this study was Mann-Whitney U Test.Results: There was a significant difference in cognitive function in the attention domain with the trail making test sub-test and the memory domain with the digit pan sub-test after the CST is finished. One month after CST is completed, there were significant differences in cognitive function, in the memory domain.Discussion: The elderly group with MCI given CST has a different cognitive function than elderly group who are not given CST.Keywords: Cognitive function, elderly, mild cognitive impairment, nursing houseABSTRAKPendahuluan: Gangguan kognitif ringan atau mild cognitive impairment (MCI) merupakan proses transisi antara penurunan kognitif normal dan demensia yang perlu diintervensi. Salah satu intervensi non-farmakologis yang dapat dilakukan adalah cognitive stimulation therapy (CST). Banyak penelitian menunjukkan bahwa CST dapat menstabilkan dan/meningkatkan fungsi kognitif pada lansia dengan MCI.Tujuan: Untuk mengetahui pengaruh intervensi CST terhadap fungsi kognitif lansia dengan MCI.Metode: Studi eksperimental pada subjek lansia usia 60 tahun yang dibagi menjadi kelompok eksperimen dan kontrol yang masing-masing terdiri dari 4 subjek. Kelompok eksperimen dilakukan CST dua kali seminggu sebanyak lima belas kali pertemuan, tidak pada kelompok kontrol. Seluruh subjek dilakukan pemeriksaan kognitif dengan menggunakan instrumen neuropsikologi sebelum, sesudah, dan satu bulan setelah CST selesai. Analisis statistik menggunakan Mann- Whitney U test.Hasil: Terdapat perbedaan fungsi kognitif yang signifikan pada domain atensi dengan subtes Trail Making Test dan domain memori dengan subtes digit span setelah CST selesai. Satu bulan setelah CST selesai, terdapat perbedaan fungsi kognitif yang signifikan pada domain memori.Diskusi: Kelompok lansia dengan MCI yang diberikan CST memiliki fungsi kognitif yang berbeda dengan kelompok lansia yang tidak diberikan CST.Kata kunci: Fungsi kognitif, gangguan kognitif ringan, lansia, panti wreda  

scholarly journals Blueberry Extracts Supplementation Improves Cognitive Function in Elderly Patients with Mild Cognitive Impairment (P14-013-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yugang Jiang ◽  
Shoudan Sun
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Elderly Patients ◽  
Natural Science ◽  
Intervention Study ◽  
The Elderly ◽  
The State ◽  
Control Group ◽  
Cognitive Aptitude

Abstract Objectives An intervention study was performed to determine if supplement containing blueberry extracts could improve cognitive function in the elderly patients with mild cognitive impairment (MCI). Methods Forty six MCI patients participated in the intervention study were paired based on their age, education level and initial the basic cognitive aptitude test (BCAT) scores and then randomly assigned to the intervention group (n = 23, which received 1.0 g/day of blueberry extracts) or blank control group (n = 23) . The endpoint was the improvement in cognitive function as evaluated by BCATs. All parameters were measured before and after the treatment period of 12 weeks. Results After 12 weeks of intervention, we observed significant improvement in their total BCAT score, space imagery efficiency, working memory and recognition memory of subjects in patients with blueberry extracts supplementation comparing to those in the control group (P = 0.006, 0.023, 0.000, 0.005, respectively). However the levels of inflammatory factors (IL-6 and TNF-α in serum) showed no significant changes after intervention. Conclusions The data indicated that blueberry has a beneficial effect on cognitive function of the elderly MCI patients, which might provide therapeutic potential for Alzheimer's disease. Funding Sources This work was supported by the State Key Program of National Natural Science Foundation of China and the State Key Program of National Natural Science Foundation of Tianjin. Supporting Tables, Images and/or Graphs

scholarly journals Effects of health education in the elderly with mild cognitive impairment

2018 ◽  
Vol 71 (suppl 2) ◽  
pp. 801-810 ◽  
Author(s):  
Francine Golghetto Casemiro ◽  
Diana Monteiro Quirino ◽  
Maria Angélica Andreotti Diniz ◽  
Rosalina Aparecida Partezani Rodrigues ◽  
Sofia Cristina Iost Pavarini ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Health Education ◽  
The Elderly ◽  
Anxiety Symptoms ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Cognitive State ◽  
Paired Samples ◽  
Education Group

ABSTRACT Objective: to analyze the effects of health education on both cognition and depressive/anxiety symptoms in the elderly with Mild Cognitive Impairment (MCI). Method: this is a randomized and controlled clinical trial. Participants (n=22) were recruited from a specialized outpatient clinic, and assigned into two groups: a Health Education Group (HEG) (n=10) and a Control Group (CG) (n=12). The participants were evaluated before and after the intervention, which was composed of classes and dynamics. The intervention consisted of 20 meetings, over a period of five months. The assessment was performed by means of the Addenbrooke’s Cognitive Examination – Revised (ACER), the Mini-Mental State Examination to access participant’s cognitive state, and the Beck’s Scale to access depressive/anxiety symptoms. A Memory Complaints Scale (EQM) was also used. The analysis was carried out using the Student’s t test for paired samples. Results: the HEG group demonstrated an improvement in attention/orientation (p= 0,026), memory (p=0.001), language (p= 0.033), and ACE-R (p= 0.003). On the other hand, the CG did not present improvement. Conclusion: the results highlight the importance of non-pharmacological interventions in older adults with MCI to reduce cognitive deficits.

scholarly journals The Effect of Chinese Square Dance Exercise on Cognitive Function in Older Women With Mild Cognitive Impairment: The Mediating Effect of Mood Status and Quality of Life

2021 ◽  
Vol 12 ◽  
Author(s):  
Jindong Chang ◽  
Wenbing Zhu ◽  
Jia Zhang ◽  
Liming Yong ◽  
Ming Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nursing Home ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Older Women ◽  
Indirect Effect ◽  
Control Group ◽  
Post Test

The present study aimed to assess the effects of square dance exercise on the cognitive function and quality of life in older women with mild cognitive impairment and to investigate the mediating role of a depressed mood and reduced quality of life in the relationship between square dance exercise and cognition. The study design was a single-blind whole-group controlled trial. A total of 136 eligible participants were divided according to their nursing home into either an experimental or control group. The nursing home grouping was determined by the drawing of lots. The Montreal Cognitive Assessment (MoCA), Quality of Life (SF-12) and Geriatric Depression Scale (GDS-15) were used to assess participants at baseline, week 9, and week 18, respectively. Generalized estimating equations (GEE) were used to compare the results at baseline with mid-test and post-test changes in cognitive function and quality of life. Maximum likelihood estimation (ML) and robust standard errors were used to perform the mediation model. The study results indicated that the experimental group (compared to the control group) had a significant improvement in cognitive function, quality of life, and mood state at baseline in the mid-test and post-test results. The results of this 18-week experiment showed that the exercise–cognition relationship was significantly mediated by a reduction in depressive symptoms (indirect effect: β = −0.375; 95% CI = −0.864 to −0.069) and an improvement in quality of life (indirect effect: β = −0.678; 95% CI = −1.222 to −0.290). This study revealed the effects of moderate-intensity square dance exercise on cognitive function and quality of life in older Chinese women with mild cognitive impairment and explored the potential mediating mechanisms. These findings can be used to inform the development of public health policies to promote brain health in older adults with mild cognitive impairment.

scholarly journals Neuropsychological Impairments and Their Cognitive Architecture in Mild Cognitive Impairment (MCI) with Lewy Bodies and MCI-Alzheimer’s Disease

2021 ◽  
pp. 1-11
Author(s):  
Joanna Ciafone ◽  
Alan Thomas ◽  
Rory Durcan ◽  
Paul C Donaghy ◽  
Calum A Hamilton ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Executive Function ◽  
Mild Cognitive Impairment ◽  
Processing Speed ◽  
Lewy Bodies ◽  
Trail Making Test ◽  
Neuropsychological Profile ◽  
Trail Making

Abstract Objective: The present study aimed to clarify the neuropsychological profile of the emergent diagnostic category of Mild Cognitive Impairment with Lewy bodies (MCI-LB) and determine whether domain-specific impairments such as in memory were related to deficits in domain-general cognitive processes (executive function or processing speed). Method: Patients (n = 83) and healthy age- and sex-matched controls (n = 34) underwent clinical and imaging assessments. Probable MCI-LB (n = 44) and MCI-Alzheimer’s disease (AD) (n = 39) were diagnosed following National Institute on Aging-Alzheimer’s Association (NIA-AA) and dementia with Lewy bodies (DLB) consortium criteria. Neuropsychological measures included cognitive and psychomotor speed, executive function, working memory, and verbal and visuospatial recall. Results: MCI-LB scored significantly lower than MCI-AD on processing speed [Trail Making Test B: p = .03, g = .45; Digit Symbol Substitution Test (DSST): p = .04, g = .47; DSST Error Check: p < .001, g = .68] and executive function [Trail Making Test Ratio (A/B): p = .04, g = .52] tasks. MCI-AD performed worse than MCI-LB on memory tasks, specifically visuospatial (Modified Taylor Complex Figure: p = .01, g = .46) and verbal (Rey Auditory Verbal Learning Test: p = .04, g = .42) delayed recall measures. Stepwise discriminant analysis correctly classified the subtype in 65.1% of MCI patients (72.7% specificity, 56.4% sensitivity). Processing speed accounted for more group-associated variance in visuospatial and verbal memory in both MCI subtypes than executive function, while no significant relationships between measures were observed in controls (all ps > .05) Conclusions: MCI-LB was characterized by executive dysfunction and slowed processing speed but did not show the visuospatial dysfunction expected, while MCI-AD displayed an amnestic profile. However, there was considerable neuropsychological profile overlap and processing speed mediated performance in both MCI subtypes.

scholarly journals Feasibility and Tolerability of a Culture-Based Virtual Reality (VR) Training Program in Patients with Mild Cognitive Impairment: A Randomized Controlled Pilot Study

2020 ◽  
Vol 17 (9) ◽  
pp. 3030 ◽  
Author(s):  
Jong-Hwan Park ◽  
Yung Liao ◽  
Du-Ri Kim ◽  
Seunghwan Song ◽  
Jun Ho Lim ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Training Program ◽  
Test Performance ◽  
Digit Span ◽  
Training Group ◽  
Control Group ◽  
Vr Training

The present study examined whether a culture-based virtual reality (VR) training program is feasible and tolerable for patients with amnestic mild cognitive impairment (aMCI), and whether it could improve cognitive function in these patients. Twenty-one outpatients with aMCI were randomized to either the VR-based training group or the control group in a 1:1 ratio. The VR-based training group participated in training for 30 min/day, two days/week, for three months (24 times). The VR-based program was designed based on Korean traditional culture and used attention, processing speed, executive function and memory conditions to stimulate cognitive function. The adherence to the culture-based VR training program was 91.55% ± 6.41% in the VR group. The only adverse events observed in the VR group were dizziness (4.2%) and fatigue (8.3%). Analysis revealed that the VR-based training group exhibited no significant differences following the three-month VR program in Korean Mini-Mental State Examination (K-MMSE) scores, working memory functions such as performance on the digit span test, or in Stroop test performance and word fluency. We conclude that although the 12-week culture-based VR training program did not improve cognitive function, our findings revealed that the culture-based VR training program was feasible and tolerable for participants with aMCI.

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