Technologies in Bilayer Tablet Manufacturing: A Review

Author(s):  
Mayuri B. Patil ◽  
Priyanka M. Salve ◽  
Shital V. Sonawane ◽  
Avish D. Maru ◽  
Jayshree S. Bhadane ◽  
...  

Bilayer tablet is a recent time for the successful development of controlled release formulation along with various quality to provide a way of the successful drug delivery system. Over the past 30 years stated that the cost and complications involved in marketing new drug entities have increased, with consequent recognition of therapeutic advantages of controlled drug delivery, greater attention has been concentration on development of sustained or controlled release drug delivery systems. Bilayer tablet it is used in the different aspect for anti-inflammatory and analgesic. Bilayer tablet incidental release of two drugs in combination, separate two incompatible substance and also for sustained release tablet in which one layer is immediate release as initial dose and second layer is maintenance dose. Bilayer tablet is enhancing beneficial technology to control the shortcoming of the single layered tablet. There is various application used in the bilayer tablets.

Materials ◽  
2018 ◽  
Vol 11 (2) ◽  
pp. 281 ◽  
Author(s):  
Yong Xie ◽  
Xinxin Ma ◽  
Xujie Liu ◽  
Qingming Long ◽  
Yu Wang ◽  
...  

Author(s):  
Sreeja C Nair ◽  
Karthika Ramesh ◽  
Krishnapriya M ◽  
Asha Paul

ABSTRACTObjective: The objective behind our study is that a mucoadhesive rectal hydrogel chitosan sodium alginate carbamazepine (CBZ) microspheres forthe purpose of controlled release for the treatment of epilepsy to avoid the possible side effects.Methods: The study was conducted to formulate controlled release chitosan sodium alginate CBZ microspheres with the dispersion of CBZ into thenatural polymers chitosan and sodium alginate forming microspheres conducting along with their evaluation studies.Results: The formulated microspheres were subjected to various evaluation parameters, and all the physical parameters examined are within theacceptable limits. Further, the optimized microsphere formulation (CM5) was characterized. Hence, the developed optimized microsphere formulation(CM5) seems to be a viable substitute to conventional drug delivery system for the effective management of epilepsy.Conclusion: The prepared formulation also provides a desired CBZ loaded sodium alginate microspheres with the controlled release drug delivery.Keywords: Carbamazepine, Sodium alginate microspheres, Particle size.


2020 ◽  
Vol 113 (5) ◽  
pp. 2061-2068
Author(s):  
Jia-Wei Tay ◽  
Dong-Hwan Choe ◽  
Ashok Mulchandani ◽  
Michael K Rust

Abstract Here, we review the literature on the development and application of hydrogel compounds for insect pest management. Researchers have used hydrogel compounds for the past few decades to achieve the controlled release of various contact insecticides, but in recent years, hydrogel compounds have also been used to absorb and deliver targeted concentrations of toxicants within a liquid bait to manage insect pests. The highly absorbent hydrogel acts as a controlled-release formulation that keeps the liquid bait available and palatable to the target pests. This review discusses the use of various types of hydrogel compounds in pest management based on different environmental settings (e.g., agricultural, urban, and natural areas), pest systems (e.g., different taxa), and modes of insecticide delivery (e.g., spray vs bait). Due to their unique physicochemical properties, hydrogel compounds have great potential to be developed into new and efficacious pest management strategies with minimal environmental impact. We will also discuss the future research and development of hydrogels in this review.


Author(s):  
JINGYI CHEN ◽  
TENGJIAO WANG ◽  
DANIEL MEEKER ◽  
MARK SMELTZER

2018 ◽  
Vol 340 ◽  
pp. 2-8 ◽  
Author(s):  
Juan L. Paris ◽  
Christophoros Mannaris ◽  
M. Victoria Cabañas ◽  
Robert Carlisle ◽  
Miguel Manzano ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document