Relationship of selenium consumption and the improvement of cognitive performance in humans and animals: a systematic review
Introduction: The aging process is characterized by morphological, physiological, biochemical and psychological changes that depend on the lifestyle. This process is the result of the accumulation of molecular and cellular damage throughout life, leading to a gradual decrease in physical and mental capacity, and greater chances of the development of pathologies such as the decline in cognitive function. Studies show that adequate consumption of foods containing selenium (Se) acts to inhibit the production of free radicals, reducing the damage caused by oxidative stress. Therefore, the aim of this study was to investigate the relationship between selenium consumption and the maintenance of cognitive function. Methods:A systematic review of scientific articles was carried out to analyze the relationship between Se consumption and cognitive function in the elderly. The identification of the articles was carried out in the electronic databases Pubmed, MEDLINE and LILACS, by two independent researchers. In all databases, the search was performed using the Results: The search resulted in 270 studies, however, applying the inclusion and exclusion criteria, eight articles were selected. Conclusion: We conclude that an adequate intake of Se must be indicated in order to maintain the brain function. In summary, the articles discussed in the presente study show a high relation of Se consumption and the improvement of cognitive performance, both in humans and in animals.