Clinicopathological feature of follicular pancreatitis

PurposeThe prognostic value of caveolin-1 in prostate cancer remains uncertain. Hence, this meta-analysis was performed to evaluate the prognostic value of caveolin-1 in prostate cancer, as well as ascertain the relationship between caveolin-1 expression and clinicopathological characteristics of prostate cancer patients.MethodsThe PubMed, Embase, Chinese National Knowledge Infrastructure and Chinese Biology Medicine databases were electronically searched to retrieve published studies on caveolin-1 expression in prostate cancer. After study selection and data extraction, the meta-analysis was conducted using Review manager 5.3 software. Odds ratio (OR) with 95% confidence interval (CI) was used to estimate the pooled effect. Funnel plot was used to assess publication bias.ResultsA total of ten studies were enrolled, which included 3976 cases of prostate cancer, 72 cases of high-grade intraepithelial neoplasia (HGPIN), and 157 normal controls. Results of the meta-analysis showed that the positive rate of caveolin-1 expression in prostate cancer was 18.28 times higher than that in normal control (OR= 18.28, 95% CI: 9.02–37.04, p<0.01), and 4.73 times higher than that in HGPIN (OR= 4.73, 95% CI: 2.38–9.42, p<0.01). The relationship between caveolin-1 and clinicopathological characteristics of prostate cancer showed that the differences in caveolin-1 expression in patients with prostate-specific antigen (PSA) >10 vs. ≤ 10 (OR=2.09, 95% CI: 1.35–3.22, p<0.01), differentiation degree low vs. medium/high (OR=2.74, 95% CI: 1.84–4.08, p<0.01), TNM stage T3+T4 vs. T1+T2 (OR=2.77, 95% CI: 1.78–4.29, p<0.01), and lymph node metastasis present vs. absent (OR=2.61, 95% CI: 1.84–3.69, p<0.01) were statistically significant. The correlation analysis between caveolin-1 and the survival time of patients with prostate cancer demonstrated that caveolin-1 was closely related to the prognosis of prostate cancer patients (HR=1.50, 95% CI: 1.28–1.76, p<0.01).ConclusionCaveolin-1 is overexpressed in prostate cancer, which can serve as a risk factor and adverse clinicopathological feature of prostate cancer. Caveolin-1 can also predict poor survival in prostate cancer patients after radical prostatectomy.

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Clinicopathological Feature of Colorectal Cancer Detected by Fecal Occult Blood Test.

The Japanese Journal of Gastroenterological Surgery ◽

10.5833/jjgs.32.1184 ◽

1999 ◽

Vol 32 (5) ◽

pp. 1184-1191 ◽

Cited By ~ 1

Author(s):

Shiro Nakae ◽

Yoshio Ishikawa ◽

Tetsuya Kuniyasu ◽

Muneharu Konishi ◽

Kunihiko Kaneda ◽

...

Keyword(s):

Colorectal Cancer ◽

Blood Test ◽

Fecal Occult Blood Test ◽

Occult Blood ◽

Fecal Occult Blood ◽

Clinicopathological Feature ◽

Occult Blood Test ◽

Fecal Occult

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CLINICOPATHOLOGICAL FEATURE AND PROGNOSIS OF AGED PATIENTS OVER 75 YEARS WITH COLORECTAL CANCER

The journal of the Japanese Practical Surgeon Society ◽

10.3919/ringe1963.51.1418 ◽

1990 ◽

Vol 51 (7) ◽

pp. 1418-1425

Author(s):

Yoichi SAKURAI ◽

Akahito AOKI ◽

Shigeo OKAZERI ◽

Toshio KANAI ◽

Hideo SHIMADA ◽

...

Keyword(s):

Colorectal Cancer ◽

Clinicopathological Feature ◽

Aged Patients

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Triple-negative invasive breast carcinoma: the association between the sonographic appearances with clinicopathological feature

Scientific Reports ◽

10.1038/s41598-018-27222-6 ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 3

Author(s):

Jia-wei Li ◽

Kai Zhang ◽

Zhao-ting Shi ◽

Xun Zhang ◽

Juan Xie ◽

...

Keyword(s):

Breast Carcinoma ◽

Triple Negative ◽

Invasive Breast Carcinoma ◽

Clinicopathological Feature

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Infleunce of Body Mass Index (BMI) on Outcome of Colon Cancer in Relationships with Other Clinicopathological Factors

Diyala Journal of Medicine ◽

10.26505/djm.21026060526 ◽

2021 ◽

Vol 21 (2) ◽

pp. 52-63

Author(s):

Ahmad A Mubarak ◽

◽

Alaa H Mustaf

Keyword(s):

Body Mass Index ◽

Colon Cancer ◽

Body Mass ◽

Cancer Recurrence ◽

Clinicopathological Feature ◽

Clinicopathological Factors ◽

Primary Tumors ◽

Female Ratio ◽

Oncology Center ◽

Colon Cancer Recurrence

Background: Colon cancer is the third most common cancer. High (BMI) contributes hazardously for several types of malignancies including colon cancer while the effect of BMI as a prognostic factor is poorly defined. Objective: Demonstrating the influence of increasing (BMI) on colon cancer recurrence. Patients and Methods: Case-control study involved a sample of 312 patients and 131 patients were excluded from this study and only 181 patients of colon cancer are included in the study with stage 2 and 3 who did underwent a surgical operation and received adjuvant chemotherapy recruited from an oncology teaching hospital, Al Jawad oncology center (Alkadhemiya hospital) and Babylon Oncology center. Results: The study involved 181 patients of colon cancer patients with mean age of 56.25 ±11.74years the highest proportion of study patients (90.6%) were aged more than 40yrs with a male to female ratio (1.2:1). Overweight patients constituted 39.2% and obese 23.8% and normal body weight 37%. In this study majority of tumors are ulcerating for about 72.5% and sigmoid and left side colon was the most common site of the tumor in about 53% with stage three is a most common type. Regarding recurrence, 54.1% of study patients have recurrence, and the majority of the 41.8% occurs between 1-3years after primary tumors diagnoses and treatment with a high prevalence of recurrence was seen in obese patients (74.4%) with a significant association between prevalence of recurrence and increasing BMI. In this study, 61.2% of patients with lymphovascular invasion have recurrences of malignancy with significant associations between recurrences and LVIe. Also more than 50% of patient older than 40years got recurrences with significant associations between recurrences with age of patients. In this study we take the effect of each clinicopathological feature on the outcome of colon cancer and then to excluded its effect by logistic regression to see the effect of only BMI on the outcome of colon cancer. Conclusion: Increase body mass index is associated with increase recurrence of colon cancer Keywords: Colon cancer recurrence, body mass index, Clinicopathological Factors

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Clinicopathological Feature of Japanese Breast Cancer Patients with a History of Gynecological Hormone Therapy

Annals of Oncology ◽

10.1093/annonc/mdu435.46 ◽

2014 ◽

Vol 25 ◽

pp. v54

Author(s):

Akemi Kataoka ◽

Miho Ichida ◽

Rie Kurabayashi ◽

Sachiyo Nomura ◽

Sadako Akashi ◽

...

Keyword(s):

Breast Cancer ◽

Hormone Therapy ◽

Cancer Patients ◽

Clinicopathological Feature ◽

Breast Cancer Patients ◽

History Of

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Upregulation of miR-21 Expression in Gastric Cancer and Its Clinicopathological Feature Association

Journal of Gastrointestinal Cancer ◽

10.1007/s12029-021-00691-1 ◽

2021 ◽

Author(s):

Fatima Ezzahra Rihane ◽

Driss Erguibi ◽

Maryame Lamsisi ◽

Farid Chehab ◽

Moulay Mustapha Ennaji

Keyword(s):

Gastric Cancer ◽

Clinicopathological Feature ◽

Feature Association

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Clinicopathological feature and long-term prognosis of apocrine carcinoma of the breast in Japanese women

Breast Cancer Research and Treatment ◽

10.1007/s10549-004-9495-z ◽

2004 ◽

Vol 88 (1) ◽

pp. 49-54 ◽

Cited By ~ 24

Author(s):

Hideya Takeuchi ◽

Kohichi Tsuji ◽

Hiroaki Ueo ◽

Tadashi Kano ◽

Yoshihiko Maehara

Keyword(s):

Japanese Women ◽

Clinicopathological Feature ◽

Apocrine Carcinoma ◽

Carcinoma Of The Breast ◽

Long Term Prognosis

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Comparison of the Clinical and Immunohistochemical Features, Including Anaplastic Lymphoma Kinase (ALK) and p53, in Inflammatory Myofibroblastic Tumours

Journal of International Medical Research ◽

10.1177/147323000903700332 ◽

2009 ◽

Vol 37 (3) ◽

pp. 867-877 ◽

Cited By ~ 20

Author(s):

You-Hua Jiang ◽

Bo Cheng ◽

Ming-Hua Ge ◽

Ye Cheng ◽

Gu Zhang

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Recurrent Disease ◽

Prognostic Indicators ◽

Clinicopathological Feature ◽

Negative Group ◽

P53 Expression ◽

Anaplastic Lymphoma ◽

Additional Surgery ◽

Alk Positive

This retrospective study evaluated 15 cases of inflammatory myofibroblastic tumours (IMTs) to determine histological atypicality, clinicopathological features, outcomes, and expression of anaplastic lymphoma kinase-1 (ALK1) and p53, to assess potential pathological prognostic indicators. Nine patients with complete follow-up had no evidence of recurrence, including two with recurrent disease who were treated with additional surgery. Six patients had local recurrence and distant metastasis. Six (40.0%) tumours showed cellular atypicality. Significant correlations were found between histological atypicality and recurrence and metastasis. Recurrence was documented in 25.0% of ALK-positive and 63.6% ALK-negative IMTs, whereas metastasis was confined to the ALK-negative group. Recurrence and metastasis were documented in 50.0% and 25.0% of p53-positive IMTs, respectively, and in 57.1% and 57.1%, respectively, of the p53-negative IMTs. The IMT cases had high recurrence and metastasis and there were significant correlations between histological atypicality and recurrence and metastases, and between absence of ALK reactivity and recurrence. No correlation was found between p53 expression and any clinicopathological feature of IMT.

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