scholarly journals Brief communication (Original). Correlation of glycated albumin with self blood glucose monitoring in diabetic patients on hemodialysis taking erythropoietin

2014 ◽  
Vol 8 (3) ◽  
pp. 387-392
Author(s):  
Khalidah M. Bador ◽  
Sharifah K.A. Kamaruddin ◽  
Norita T. Yazid
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Glycated Albumin ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Bromocresol Green ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Albumin Ratio ◽  
Significant Difference

AbstractBackground: Serum glycated albumin (GA) is a marker of glycemic control in diabetic renal patients, but studies were limited by the use of few random glucose values to define glycemic control.Objectives: To determine whether GA correlated with self blood glucose monitoring is better than HbA1c in hemodialyzed diabetic patients taking erythropoietin.Methods: This was a cross-sectional study of diabetic patients on hemodialysis with and without erythropoietin. GA was measured by ELISA and HbA1c by ion-exchange HPLC. GA was reported as the GA/albumin ratio where albumin was measured using bromocresol green. The average capillary blood glucose level over the preceding three months (CBG) was calculated from self-reported daily prebreakfast, prelunch, and prebed glucose meter readings.Results: Thirty-four patients were recruited; 18 were taking erythropoietin (6000 units per week) and 16 had never received erythropoietin. HbA1c correlated poorly with CBG in patients taking erythropoietin (r = -0.014, P = 0.96) compared with patients without erythropoietin (r = 0.579, P = 0.02). The correlation of GA/albumin ratio with CBG in the erythropoietin group (r = 0.612, P = 0.007) was similar to the nonerythropoietin group (r = 0.854, P < 0.001). The slope for HbA1c versus CBG was 2.8-fold greater in patients without erythropoietin compared with those taking erythropoietin. There was no significant difference in the slopes for GA/albumin ratio versus CBG between the two patient groups (P > 0.05).Conclusion: In diabetic patients on hemodialysis and taking low doses of erythropoietin, GA/albumin is a better marker of glycemic control than HbA1c.

scholarly journals Blood Glucose Monitoring and Its Determinants in Diabetic Patients: A Cross-Sectional Study in Shandong, China

2018 ◽  
Vol 9 (5) ◽  
pp. 2055-2066 ◽  
Author(s):  
Abdul Marouf Raoufi ◽  
Xue Tang ◽  
Zhengyue Jing ◽  
Xinyi Zhang ◽  
Qiongqiong Xu ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glucose Monitoring ◽  
Cross Sectional Study ◽  
Blood Glucose Monitoring ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals MO651DIABETES CARE IN HAEMODIALYSIS TREATMENT : ADVANCES IN 2020

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Clementine Dillmann ◽  
Clemence Tollard ◽  
Yoann-Francois Chantrel ◽  
Hanane Mountassir ◽  
Sophie Brokhes-Lecalvez ◽  
...  
Keyword(s):  
Blood Glucose ◽  
High Risk ◽  
Glycemic Control ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Diabetic Patients ◽  
Dialysis Unit ◽  
Foot Injury

Abstract Background and Aims Management of diabetes and follow-up of haemodialysis patients are still poorly standardized. The objective of this study is to establish a descriptive inventory of all routine parameters for monitoring diabetes and glycemic control by Continuous Glucose Monitoring (CGM). Method The study recruited 32 diabetic patients in a medical dialysis unit. Glycemic control was assessed using CGM (FreeStyle Free Pro®) over at least 11 days with measurement of: mean blood glucose level, percentage of blood glucose level: &lt; 70 mg/dl (TBR), between 70 and 180 mg/dl (TIR), and &gt; 180 mg/dl (TAR). The results are expressed in average or median [25-75 percentiles]. SPSS® statistical analyses compared extra and per dialytic periods. Results Patients’ mean age was 71±8 years, diabetes duration was 21±6.5 years (87.5% T2DM), mean weight was 77±13kg, HbA1c was 7±0.98%, 98% had a high risk of foot injury (Grade 2 and 3) . Only 46.8% of the patients were followed by a diabetes specialist and 84.3% were treated with insulin and 18.75% received oral medication while only 50% performed self blood glucose-monitoring. The average blood glucose level was 133±13 mg/dl (∼1000 measurements). CGM results for 32 patients over the total period were: TIR at 70% [58-76], TAR at 15% [4.6-29], and TBR at 9.6% [3.7-20].Per-dialytic TIR (84%; [76-93]) was significantly higher (p=0.02) than extra-dialytic TIR (68%; [56-75]). Per-dialytic TAR (5.5%; [0.0-10.7]) was significantly lower (p&lt;0.01) than extra-dialytic TAR (14%; [3.6-29]). TBR did not vary significantly. Conclusion The majority of patients were treated with insulin but only 50% performed self- of blood glucose. Hypoglycaemia was lower during dialysis period. 98% of patients had a high risk of foot injury. CGM could be a usefull tool for the evaluation of glycemic profile of haemodialysis patients, and allows a better adjustment of their treatment.

scholarly journals Role of free style Libre-Flash Glucose Monitoring: Glycemic control of Type-1 Diabetes

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Imad Mohamed ◽  
Iman M. Talaat ◽  
Hamed A. Alghamdi ◽  
Gamal Allam
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Military Hospital ◽  
Diabetic Patients ◽  
Flash Glucose Monitoring ◽  
Significant Difference

Background & Objective: Type-1 diabetics (T1D) usually do not meet guidelines for glycaemic control. This study aimed to determine the benefit of free style libre-flash glucose monitoring system (FSL-FGM) in lowering glycated hemoglobin (HbA1c) in poorly controlled T1D patients. Methods: This prospective two single arm clinical study included 273 T1D patients, and data collected at one, six and 18 months with concomitant extraction of samples for HbA1c basal and at six and 18 months. The study was conducted in Prince Mansour Military Hospital at Taif, Saudi Arabia from June 2017 to November 2018. Results: HbA1c % was significantly diminished in patients used FSL-FGM at 6 and 18 months. The median percentage difference in HbA1c at 6 and 18 months versus basal was significantly decreased in those using FSL-FGM. Within diabetics using FSL-FGM, the median difference in HbA1c after 18 months was significantly decreased in patients with HbA1c >10% compared to those with HbA1c <10%. Estimated HbA1c by FSL showed a significant correlation with HbA1C assayed in the blood. The snapshot information showed a highly significant difference in average glucose with low significant difference in hypoglycemia parameters. The FSL-FGM provides significant changes in HbA1c in diabetic patients without observed risk for hypoglycemia. Conclusions: The dynamic way of blood glucose monitoring using FSL-FGM provides improvement in HbA1c in diabetic patients without observed risk for hypoglycemia. doi: https://doi.org/10.12669/pjms.37.7.4114 How to cite this:Mohamed IAA, Talaat IM, Alghamdi HA, Allam G. Role of free style Libre–Flash Glucose Monitoring: Glycemic control of Type-1 Diabetes. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4114 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Knowledge, Attitude and Practice of Blood Glucose Monitoring in Rural Area among Diabetic Patients

2018 ◽  
Vol 5 (3) ◽  
pp. 225-230
Author(s):  
Saima Shabnum ◽  
Hajra Sarwar
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Glucose Monitoring ◽  
Diabetic Control ◽  
Blood Glucose Monitoring ◽  
Diabetic Patients ◽  
Adult Males ◽  
Cross Sectional ◽  
Low Level

Background: Diabetes is main and growing health issue affecting more than 171 million peoples worldwide and the number is expected to rise to 366 million by 2030. Type 2 Diabetes will keep on accounting for 90% of all the cases. According to the WHO, Pakistan positioned seventh in pervasiveness of Diabetes. In 2011, the assessed pervasiveness of diabetes in Pakistan was generally in excess of 350 million and it is depended upon to be in excess of 550 million by year 2030. In Pakistan 9.5% of urban and 9.4% of the provincial population experience the bad effects of type 2 diabetes.  Objective: The reason for this investigation was to survey learning, conduct in regards to blood glucose observing among diabetic in rural group, Lahore. Descriptive cross sectional investigation configuration was led to evaluate learning, disposition and routine with regards to blood glucose monitoring and a sample size of 100 participants was selected for this study through convenient sampling. Data was collected from the adult males and females of Husain Abad community. Result: The result show that there was low level of knowledge, somewhat positive attitudes but very low level of practices regarding the diabetic control and glucose monitoring among the participants. Conclusion: In conclusion, it is stated that this research study the knowledge of participants towards the diabetes was not good except the definition of diabetes. The attitude was comparatively positive and good for following different blood sugar controlling measures. The practices were very poor. No one was following regular exercises, dietary modifications etcetera.Int. J. Soc. Sc. Manage. Vol. 5, Issue-3: 225-230

941-P: Frequency of Blood Glucose Monitoring in Relation to Medical Cost and Glycemic Control in Hospitalized Patients with Type 2 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 941-P
Author(s):  
LEI ZHANG ◽  
YAN GU ◽  
YUXIU YANG ◽  
NA WANG ◽  
WEIGUO GAO ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Glycemic Control ◽  
Medical Cost ◽  
Glucose Monitoring ◽  
Hospitalized Patients ◽  
Blood Glucose Monitoring

Characteristics of monitored diabetic patients by glycated haemoglobin (HbA1c)

2016 ◽  
Vol 5 (05) ◽  
pp. 4563
Author(s):  
Tariq A. Zafar
Keyword(s):  
Blood Glucose ◽  
Glycemic Control ◽  
Glycated Haemoglobin ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
Age Group ◽  
Hba1c Test ◽  
Significant Difference ◽  
Tract Infections ◽  
The Impact

Glycated haemoglobin (HbA1c) test indicates the blood glucose levels for the previous two to three months. Using HbA1c test may overcome many of the practical issues and prevent infections such as urinary tract infections (UTIs). The study aimed to evaluate the impact of glycemic control using HbA1c test to understand patient characteristics and UTIs prevalence. Glycemic control was evaluated by measuring HbA1c for a total of 208 diabetes patients who were regularly attending diabetes center in Al-Noor specialist hospital in Makkah.  The results showed that good and moderate glycemic controlled patients were 14.9% and 16.9% respectively while the poor glycemic patients were 68.3%. Among the good improved glycemic control, 83.9% were females, 48.4% were from age group (15-44y). Among the moderately improved glycemic control, 68.4% were females, 54.3% were from age group (45-64 y) with no significant difference. The total number of the patients with positive UTIs was 55 (26.4%) while the total number of patients with negative was UTIs 153 (73.6%). Among the positive UTIs, 76.3% were with poor glycemic control while only 12.3% and 11% were moderate and good improved glycemic control respectively. Among the negative UTIs, 65.3% were with poor glycemic control while only 19% and 15.7% were with moderate and good improved glycemic control respectively.  Prevalence of UTIs among diabetic patients was not significant (p > 0.05). It was concluded that HbA1c was useful monitoring tool for diabetes mellitus and may lead to improved outcomes. Using a HbA1c test may overcome many of the practical issues that affect the blood glucose tests.

Indole as a new tentative marker in exhaled breath for non-invasive blood glucose monitoring of diabetic subjects

2021 ◽  
Author(s):  
Herbert Fink ◽  
Tim Maihöfer ◽  
Jeffrey Bender ◽  
Jochen Schulat
Keyword(s):  
Blood Glucose ◽  
Diabetes Management ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Glucose Measurement ◽  
Diabetic Patients ◽  
Exhaled Breath ◽  
Invasive Approach ◽  
Test Strips ◽  
Non Invasive

Abstract Blood glucose monitoring (BGM) is the most important part of diabetes management. In classical BGM, glucose measurement by test strips involves invasive finger pricking. We present results of a clinical study that focused on a non-invasive approach based on volatile organic compounds (VOCs) in exhaled breath. Main objective was the discovery of markers for prediction of blood glucose levels (BGL) in diabetic patients. Exhaled breath was measured repeatedly in 60 diabetic patients (30 type 1, 30 type 2) in fasting state and after a standardized meal. Proton Transfer Reaction Time of Flight Mass Spectrometry (PTR-ToF-MS) was used to sample breath every 15 minutes for a total of six hours. BGLs were tested in parallel via BGM test strips. VOC signals were plotted against glucose trends for each subject to identify correlations. Exhaled indole (a bacterial metabolite of tryptophan) showed significant mean correlation to BGL (with negative trend) and significant individual correlation in 36 patients. The type of diabetes did not affect this result. Additional experiments of one healthy male subject by ingestion of lactulose and 13C-labeled glucose (n=3) revealed that exhaled indole does not directly originate from food digestion by intestinal microbiota. As indole has been linked to human glucose metabolism, it might be a tentative marker in breath for non-invasive BGM. Clinical studies with greater diversity are required for confirmation of such results and further investigation of metabolic pathways.

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