scholarly journals Impact of Inflammatory Bowel Disease upon Growth in Children and Adolescents

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
V. Moeeni ◽  
A. S. Day
Keyword(s):  
Inflammatory Bowel Disease ◽  
Weight Loss ◽  
Gastrointestinal Tract ◽  
Children And Adolescents ◽  
Linear Growth ◽  
Delayed Puberty ◽  
Childhood And Adolescence ◽  
Bowel Diseases ◽  
Inflammatory Processes ◽  
Inflammatory Bowel

The inflammatory bowel diseases (IBDs) are chronic inflammatory processes affecting the gastrointestinal tract. When diagnosed in childhood and adolescence, IBD almost always impacts adversely upon the nutritional state of the patient. Weight loss and impaired linear growth may be present at diagnosis or subsequently. Further potential nutritional consequences in childhood IBD include malnutrition, anaemia, osteopaenia, and delayed puberty. Understanding the nutritional aspects of IBD is paramount in growing children, especially those entering and advancing through puberty. This paper focuses upon the nutritional impacts of IBD in children and adolescents.

scholarly journals Nutritional impact of inflammatory bowel diseases on children and adolescents

2014 ◽  
Vol 32 (4) ◽  
pp. 403-411 ◽  
Author(s):  
Gilton Marques dos Santos ◽  
Luciana Rodrigues Silva ◽  
Genoile Oliveira Santana
Keyword(s):  
Inflammatory Bowel Disease ◽  
Children And Adolescents ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Pubertal Development ◽  
Overweight And Obesity ◽  
Delayed Puberty ◽  
Vitamin Deficiencies ◽  
Bowel Diseases ◽  
Inflammatory Bowel

OBJECTIVE: To perform a sistematiy review of the literature about the nutritional impact of inflammatory bowel diseases in children and adolescents.DATA SOURCES: A systematic review was performed using PubMed/MEDLINE, LILACS and SciELO databases, with inclusion of articles in Portuguese and in English with original data, that analyzed nutritional aspects of inflammatory bowel diseases in children and adolescents. The initial search used the terms "inflammatory bowel diseases" and "children" or "adolescents" and "nutritional evaluation" or "nutrition deficiency". The selection of studies was initially performed by reading the titles and abstracts. Review studies and those withouth data for pediatric patients were excluded. Subsequently, the full reading of the articles considered relevant was performed.RESULTS: 237 studies were identified, and 12 of them were selected according to the inclusion criteria. None of them was performed in South America. During the analysis of the studies, it was observed that nutritional characteristics of patients with inflammatory bowel disease may be altered; the main reports were related to malnutrition, growth stunting, delayed puberty and vitamin D deficiency.CONCLUSION: There are nutritional consequences of inflammatory bowel diseases in children and adolescents, mainly growth stunting, slower pubertal development, underweight and vitamin deficiencies. Nutritional impairments were more significant in patients with Crohn's disease; overweight and obesity were more common in patients with ulcerative rectocolitis. A detailed nutritional assessment should be performed periodically in children and adolescents with inflammatory bowel disease.

scholarly journals The Influence of Probiotics on the Firmicutes/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease

2020 ◽  
Vol 8 (11) ◽  
pp. 1715
Author(s):  
Spase Stojanov ◽  
Aleš Berlec ◽  
Borut Štrukelj
Keyword(s):  
Inflammatory Bowel Disease ◽  
Weight Loss ◽  
Gastrointestinal Tract ◽  
Bowel Disease ◽  
Important Influence ◽  
Considerable Evidence ◽  
Bacterial Phyla ◽  
Genus Lactobacillus ◽  
Inflammatory Bowel ◽  
Treatment Of Obesity

The two most important bacterial phyla in the gastrointestinal tract, Firmicutes and Bacteroidetes, have gained much attention in recent years. The Firmicutes/Bacteroidetes (F/B) ratio is widely accepted to have an important influence in maintaining normal intestinal homeostasis. Increased or decreased F/B ratio is regarded as dysbiosis, whereby the former is usually observed with obesity, and the latter with inflammatory bowel disease (IBD). Probiotics as live microorganisms can confer health benefits to the host when administered in adequate amounts. There is considerable evidence of their nutritional and immunosuppressive properties including reports that elucidate the association of probiotics with the F/B ratio, obesity, and IBD. Orally administered probiotics can contribute to the restoration of dysbiotic microbiota and to the prevention of obesity or IBD. However, as the effects of different probiotics on the F/B ratio differ, selecting the appropriate species or mixture is crucial. The most commonly tested probiotics for modifying the F/B ratio and treating obesity and IBD are from the genus Lactobacillus. In this paper, we review the effects of probiotics on the F/B ratio that lead to weight loss or immunosuppression.

Accurate and rapid microfluidic ELISA to monitor Infliximab titers in patients with inflammatory bowel diseases

The Analyst ◽  
2022 ◽  
Author(s):  
Inês Iria ◽  
Ruben R.G. Soares ◽  
Eduardo Brás ◽  
Virginia Chu ◽  
João Gonçalves ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Gastrointestinal Tract ◽  
Chronic Inflammation ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Inflammatory bowel disease (IBD) is a term used to describe disorders that involve chronic inflammation in the gastrointestinal tract, affecting more than 6.8 million people worldwide.1 Biological therapy is used...

Crohn’s disease

2018 ◽  
Vol 11 (8) ◽  
pp. 435-442
Author(s):  
James Franklin
Keyword(s):  
Inflammatory Bowel Disease ◽  
Weight Loss ◽  
Crohn’S Disease ◽  
Abdominal Pain ◽  
Gastrointestinal Tract ◽  
Crohn's Disease ◽  
Terminal Ileum ◽  
Bowel Disease ◽  
Rare Condition ◽  
Inflammatory Bowel

Crohn’s disease is a chronic relapsing gastrointestinal condition. It is an inflammatory bowel disease that can affect any part of the gastrointestinal tract from mouth to anus, but most commonly affects the terminal ileum and colon. Individuals can present with a wide variety of symptoms, but diarrhoea, abdominal pain and weight loss are the most common. It is a rare condition, but GPs play an important role in recognising Crohn’s disease and supporting patients through their lifelong treatment.

scholarly journals Uso de probióticos na nutrição de cães com Doença Inflamatória Intestinal (DII) – uma atualização

2021 ◽  
Vol 4 (5) ◽  
pp. 75-87
Author(s):  
Cláudio Marcos Rocha-de-Souza ◽  
◽  
Ana Carolina Aor Zaqueu ◽  
Lívia Rodrigues da Cruz ◽  
Marcelo Gomes de Souza ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Weight Loss ◽  
Antibiotic Therapy ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Immunosuppressive Drugs ◽  
Intestinal Diseases ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Digestive Disorders

Canine Inflammatory Bowel Disease (IBD) is the term used to designate a group of chronic intestinal diseases, manifested by persistent or recurrent gastrointestinal signs. Known symptoms are vomiting, diarrhea, changes in appetite and weight loss. Treatment consists of a diet combined with antibiotic therapy and immunosuppressive drugs. It is currently known that changes in the microbiota profile can be used as way to prevent digestive disorders, since some probiotics offer benefits to patients with IBD, reducing symptoms and improving their immunity, however, can say that there is still no consensus regarding the recommendation of the use probiotics in inflammatory bowel diseases.

scholarly journals Pathogenetic Aspects of Oral Cavity Lesions in Inflammatory Gastrointestinal Tract Diseases

2019 ◽  
Vol 29 (4) ◽  
pp. 15-21
Author(s):  
N. S. Robakidze ◽  
O. B. Shchukina
Keyword(s):  
Inflammatory Bowel Disease ◽  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Bowel Disease ◽  
Pathological Process ◽  
Digestive Tube ◽  
Close Relationship ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Immunohistochemical Studies

Despite the similarity of many pathogenetic lesions of the gastrointestinal tract and the oral cavity, there remain unresolved issues related to the etiology and pathogenesis of dental diseases associated with inflammatory bowel diseases.Aim. Analysis and systematization of literature data on the problem of combined diseases of the oral cavity and the gastrointestinal tract.Key findings. Severe recurrent inflammatory bowel disease and the close relationship of all levels of the digestive tube create prerequisites for the development of pathological processes in the oral cavity. Despite the extensive symptoms of oral manifestations of inflammatory bowel disease, aphthous stomatitis is considered more often than other diseases. There are different opinions about the involvement of the oral mucosa in the pathological process in inflammatory bowel disease. Some authors consider the defeat of the mouth in terms of the specific localization of Crohn’s disease, others see in it only extraintestinal manifestations of the disease, along with changes in the skin, joints and eyes. Immunohistochemical studies allow you to answer individual questions of pathogenesis.Conclusion. The presented analysis of publications confirms the morphofunctional unity of various parts of the digestive system, which determines the complex mechanisms of the development of combined diseases.

Surgery

2021 ◽  
pp. 473-506
Author(s):  
Jennie Burch ◽  
Brigitte Collins
Keyword(s):  
Bariatric Surgery ◽  
Inflammatory Bowel Disease ◽  
Rectal Cancer ◽  
Weight Loss ◽  
Nursing Care ◽  
Enhanced Recovery ◽  
Gastrointestinal Surgery ◽  
Surgical Patients ◽  
Bowel Diseases ◽  
Inflammatory Bowel

The surgery chapter discusses surgical treatment for bowel diseases. There are many surgical procedures that are explored with inclusion of the indication for surgery, such as cancer or inflammatory bowel disease, and any common surgical complications so that the nurse is aware of observations to undertake. Nursing advice is added where appropriate to ensure that the nurse knows what advice might be necessary to give to the patient. Operations discussed include anterior resection to remove part of the rectum for a rectal cancer and bariatric surgery to help weight loss. Diagrams help to explain what the operation entails. Nursing care of surgical patients on the enhanced recovery pathway is included with details on preoperative, intraoperative, and postoperative care. Concise exploration of gastrointestinal surgery within this chapter can be used within clinical practice by the nurse.

scholarly journals Growth, puberty, and bone health in children and adolescents with inflammatory bowel disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hye-Young Jin ◽  
Jae-Sang Lim ◽  
Yena Lee ◽  
Yunha Choi ◽  
Seak-Hee Oh ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Bone Health ◽  
Bowel Disease ◽  
Delayed Puberty ◽  
Testosterone Levels ◽  
Inflammatory Bowel ◽  
Endocrine Complications

Abstract Background Endocrine complications such as impaired growth, delayed puberty, and low bone mineral density (BMD) can be associated with inflammatory bowel disease (IBD) in children and adolescents. This study was performed to investigate the frequency, characteristics, and outcomes of endocrine complications of IBD in children and adolescents. Methods This study included 127 patients with IBD diagnosed before 18 years of age [117 with Crohn disease (CD) and 10 with ulcerative colitis (UC)]. Growth profiles, pubertal status, 25-hydroxyvitamin D3 [25(OH)D3] levels, and BMD were reviewed retrospectively. Results Short stature was observed in 14 of 127 (11.0 %) with a mean height-SDS of -2.31 ± 0.72. During a 2-year follow-up period, height-SDS did not significantly improve, while weight-SDS significantly improved. Among 109 patients who were older than 13 (girls) or 14 (boys) years of age during the study period, 11 patients (10.1 %) showed delayed puberty, which was associated with low weight-SDS. Vitamin D deficiency was documented in 81.7 % (94/115) with the average 25(OH)D3 level of 14.5 ± 7.0 ng/mL. Lumbar BMD Z-score was below − 2 SDS in 25 of 119 patients (21.0 %). Height-SDS, weight-SDS, and body mass index (BMI)-SDS were lower in patients with osteoporosis than those without osteoporosis. When pediatric CD activity index scores were high (≥ 30), weight-SDS, BMI-SDS, insulin-like growth factor 1 (IGF-1)-SDS, and testosterone levels were significantly decreased. Conclusions Vitamin D deficiency and osteoporosis are common in pediatric IBD patients. As disease severity deteriorates, weight-SDS, IGF-1-SDS, and testosterone levels were decreased. Optimal pubertal development is necessary for bone health.

Localization and Activity of Inflammatory Bowel Disease Using 111ln Leukocyte Imaging

1988 ◽  
Vol 27 (03) ◽  
pp. 83-86 ◽  
Author(s):  
B. Briele ◽  
F. Wolf ◽  
H. J. Biersack ◽  
F. F. Knapp ◽  
A. Hotze
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Bowel Disease ◽  
Cell Uptake ◽  
Disease Extent ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Leukocyte Imaging

A prospective study was initiated to compare the clinically proven results concerning localization/extent and activity of inflammatory bowel diseases with those of 111ln-oxine leukocyte imaging. All patients studied were completely examined with barium enema x-ray, clinical and laboratory investigations, and endoscopy with histopathology. A total of 31 leukocyte scans were performed in 15 patients (12 with Crohn’s disease, 3 with ulcerative colitis). The scans were graded by comparing the cell uptake of a lesion (when present) and a bone marrow area providing a count ratio (CR). The inflammatory lesions were correctly localized on 26 leukocyte scans, and in 21 scans the scintigraphically estimated extent of disease was identical to endoscopy. In 5 cases the disease extent was underestimated, 4 scans in patients with relapse of Crohn’s disease were falsely negative, and in one patient with remission truly negative. The scintigraphically assessed disease activity was also in a good agreement with clinical disease activity based on histopathology in all cases. We conclude that leukocyte imaging provides valuable information about localization and activity of inflammatory bowel disease.

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