scholarly journals PEMERIKSAAN IVA TEST PADA WANITA USIA SUBUR DI DESA PANGKALAN LADA

2021 ◽  
Vol 4 (2) ◽  
pp. 171-174
Author(s):  
Angela Ditauli Lubis
Keyword(s):  
Human Papillomavirus ◽  
Pap Smear

Jumlah penderita kanker serviks di Indonesia semakin tinggi. Promosi kesehatan dan deteksi dini menjadi prioritas untuk mencegah dan menangani penyakit. Organisasi Kesehatan Dunia (WHO) mencatat, tiap tahun sekitar 15.000 kasus kanker serviks (leher rahim) ditemukan di Indonesia. Indonesia menjadi negara dengan jumlah kasus kanker serviks tertinggi di dunia. Kanker serviks ditandai dengan tumbuhnya sel-sel tidak normal pada leher rahim. Diperkirakan 90 persen kanker leher rahim disebabkan human papillomavirus (HPV). Insiden kanker serviks sebenarnya dapat ditekan dengan melakukan upaya pencegahan primer seperti meningkatkan atau intensifikasi kegiatan penyuluhan kepada masyarakat untuk menjalankan pola hidup sehat, menghindari faktor risiko terkena kanker, melakukan immunisasi dengan vaksin HPV dan diikuti dengan deteksi dini kanker serviks tersebut melalui pemeriksaan pap smear atau IVA (inspeksi visual dengan menggunakan asam acetat).  Saat ini cakupan “screening” deteksi dini kanker serviks di Indonesia melalui pap smear dan IVA masih sangat rendah (sekitar 5%), padahal cakupan “screening” yang efektif dalam menurunkan angka kesakitan dan angka kematian karena kanker serviks adalah 85 %. Sasaran dalam kegiatan penyuluhan ini adalah seluruh perempuan yang telah menikah di Desa Pangkalan Lada. Metode yang dilakukan dalam kegiatan ini adalah penyuluhan dan pemeriksaan IVA gratis. Kegiatan pemeriksaan IVA Test pada wanita usia subur di desa Pangkalan Lada berjalan dengan baik. Antusias dari para peserta cukup baik. Jumlah peserta yang mengikuti pemeriksaan IVA sebanyak 45 orang. Berdasarkan hasil pemeriksaan IVA yang dilakukan pada wanita usia subur di desa Pangkalan Lada, dari 40 peserta yang dilakukan pemeriksaan 10 diantaranya mengalami erosi dan 5 orang diberikan tutul albothyl dan selanjutnya disarankan untuk melakukan pap smear. Pemeriksaan IVA Test tujuan kegiatan ini adalah untuk mendeteksi dini kanker leher rahim pada wanita usia subur. Agar kegiatan pemeriksaan seperti ini dapat dilakukan secara rutin sehingga derajat kesehatan warga khususnya pada wanita-wanita di desa ini dapat meningkat dan terpantau. Kata kunci      : IVA Test, Wanita Usia Subur

Evaluation of Cervical Cancer Screening Tools; INNO-LiPA® HPV Genotyping Extra-II Assay versus E7/E6 oncoproteins, How is reliable and practical?

2021 ◽  
Vol 15 (5) ◽  
pp. 1276-1281
Author(s):  
R. Bahramabadi ◽  
M. K. Arababadi ◽  
M. Iranpour ◽  
E. Mohebbi ◽  
Z. Honarvar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Western Blot ◽  
Pap Smear ◽  
Diagnostic Methods ◽  
Screening Tools ◽  
Hpv Dna ◽  
Hpv Genotyping ◽  
Hpv E7 ◽  
Diagnostic Values

Background: High-Risk Human papillomavirus (HR-HPV) has been well established as the cervical cancer (CC) risk factor. In recent years, various diagnostic methods of human papillomaviruses (HPV) have been developed to promote sensitivity and specificity of CC screening which leads to a low mortality rate. This study aimed to compare diagnostic test metrics of two HPV diagnostic techniques, including Western blot and INNO-LiPA HPV Genotyping Extra II assay methods in asymptomatic or subclinical patients, among the South-Eastern Iranian women. Methods: 323 women were referred to the Pathology and Stem Cell Research Center, from February 2018 to January 2020. HPV-DNA with the INNO-LiPA HPV Genotyping Extra-II Assay kit and the western blot assays for HPV E7 and E6 assessment were employed. Results: Overall, 163 (50.4%) samples were dysplastic pap smear, the specificity of the HPV DNA test by INNO-LiPA HPV Genotyping Extra-II Assay test was significantly higher than the E7/E6 oncoproteins finding (67.3 vs. 49.9%), and the sensitivity was lower (96.6 vs. 74.8%), respectively. Conclusions: HR-HPV E7/E6 oncoproteins expression was evaluated as a possible novel biomarker for CC screening in pap smear as the preliminary test with satisfactory diagnostic values for HR-HPV types 16 and 18. The corresponding diagnostic values may be further improved by combining HPV DNA tests with the INNO-LiPA HPV Genotyping Extra-II test. Also, they may prove helpful for HR-HPV infection diagnosis in cases that the patients are asymptomatic or subclinical. Keywords: Cervical Cancer; Human Papillomavirus (HPV); Diagnostic Screening Programs; Oncogene Proteins

Relationship Between Pelvic Organ Prolapse and Non–Human Papillomavirus Pap Smear Abnormalities

2018 ◽  
Vol 24 (4) ◽  
pp. 315-318
Author(s):  
Kimia Menhaji ◽  
Heidi S. Harvie ◽  
Emily Cheston ◽  
Pamela J. Levin ◽  
Lily A. Arya ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Pelvic Organ Prolapse ◽  
Pap Smear ◽  
Pelvic Organ

Prevalence of Human Papillomavirus Genotypes in Routine Pap Smear of 2,562 Korean Women Determined by PCR-DNA Sequencing

2009 ◽  
Vol 39 (4) ◽  
pp. 337 ◽  
Author(s):  
Kyung-Ok Lee ◽  
Su-Jin Jeong ◽  
Min-Young Park ◽  
Hye-Soon Seong ◽  
Eun-Sim Shin ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Dna Sequencing ◽  
Pap Smear ◽  
Korean Women

scholarly journals Perception of the Saudi Community towards Human Papilloma Virus Vaccination in Jeddah, Saudi Arabia

2017 ◽  
Vol 9 (9) ◽  
pp. 158
Author(s):  
Ahlam A. Alzahrani ◽  
Nebras AlGhanaim ◽  
Samia Abdulmageed
Keyword(s):  
Cervical Cancer ◽  
Saudi Arabia ◽  
Human Papillomavirus ◽  
Pap Smear ◽  
Hpv Vaccination ◽  
Cross Sectional Study ◽  
Community Perception ◽  
Human Papillomavirus Vaccination ◽  
Cross Sectional ◽  
Males And Females

To examine the awareness and perception of Saudi community towards Human Papillomavirus Vaccination. A cross-sectional study has examined the perception and awareness of Saudi individuals towards Human Papillomavirus HPV vaccination. A sample of 278 Saudi individuals were included. A close-ended survey questionnaire was employed to collect the data of Papillomavirus HPV vaccination. Around, 78.30% female and male participants were unaware of the availability of HPV vaccination against cervical cancer. 90.06% of females supported cervical cancer screening Pap smear by gynecologist after enduring vaccination. Only, 40.66% visited the gynecologist for screening. Results demonstrated 85.77% female agreed on receiving expensive vaccination. Conversely, 97.48% supported on HPV vaccination free of charge. A lack of knowledge about HPV, Pap smear, and cervical cancer. The data obtained can be used as a standard to devise effective awareness programs. Data was collected particularly from Saudi Arabia for evaluating Saudi community perception. Both males and females were observed to be interested in taking vaccination and prevention initiatives against the cervical cancer, whereas, there is a lack of awareness observed among the males and females included in the study.

Human papillomavirus (HPV) test and PAP smear as predictors of outcome in conservatively treated adenocarcinoma in situ (AIS) of the uterine cervix

2007 ◽  
Vol 106 (1) ◽  
pp. 170-176 ◽  
Author(s):  
Silvano Costa ◽  
Giovanni Negri ◽  
Mario Sideri ◽  
Donatella Santini ◽  
Giuseppe Martinelli ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Uterine Cervix ◽  
Pap Smear ◽  
Adenocarcinoma In Situ ◽  
Predictors Of Outcome ◽  
Hpv Test

scholarly journals The Relationship between Cocaine Use and Human Papillomavirus Infections in HIV-Seropositive and HIV-Seronegative Women

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Howard Minkoff ◽  
Ye Zhong ◽  
Howard D. Strickler ◽  
D. Heather Watts ◽  
Joel M. Palefsky ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Pap Smear ◽  
Crack Cocaine ◽  
Hpv Infection ◽  
Cocaine Use ◽  
Hpv Dna ◽  
Increased Risk ◽  
Hiv Seropositive ◽  
Oncogenic Hpv

Objective. Animal data suggest that cocaine has an immunosuppressive effect, but no human studies have been conducted to assess the relation of cocaine use with human papillomavirus (HPV) infection, the viral cause of cervical cancer. Since both cocaine use and HPV infection are common among HIV-positive women, we sought to determine whether use of cocaine and/or crack influences the natural history of HPV among women with or at high risk of HIV.Methods. Women enrolled in the Women's Interagency HIV Study (2278 HIV-seropositive and 826 high-risk seronegative women) were examined every six months for up to 9.5 years with Pap smear, collection of cervicovaginal lavage (CVL) samples, and detailed questionnaires regarding health and behavior, including use of crack and cocaine (crack/cocaine). CVLs were tested for HPV DNA by PCR, with genotyping for over forty HPV types.Results. In multivariate logistic regression models, censoring women treated for cervical neoplasia, crack/cocaine use within the last six months was associated with prevalent detection of oncogenic HPV DNA (odds ratio [OR] = 1.30 (1.09–1.55)), and with oncogenic HPV-positive squamous intraepithelial lesions (SIL) (OR = 1.70 (1.27–2.27)), following adjustment for age, race, HIV-serostatus, and CD4+ T-cell count, the number of sexual partners in the past six months, and smoking. In multivariate Cox models crack/cocaine use was also associated with a trend that approached significance in regard to incident detection of oncogenic HPV-positive SIL (HR = 1.51, 95% CI 0.99–2.30), and while the rate of oncogenic HPV clearance was not related to cocaine use, the clearance of any SIL was significantly lower in those with versus those without recent crack/cocaine use (HR = 0.57, 95% CI 0.34–0.97).Conclusions. Cocaine use is associated with an increased risk of detection of both prevalent and incident oncogenic HPV infection, as well as an increased risk of HPV-positive SIL over time.

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