The Effects of Caffeic Acid Phenethyl Ester (CAPE), Royal Jelly, and Curcumin on Gene Expression of ADAMTS-1, -5, and -9 in OUMS-27 Chondrosarcoma Cells: A Preliminary Study

2013 ◽  
Vol 2 (1) ◽  
pp. 27 ◽  
Author(s):  
Sumeyya Akyol ◽  
Muradiye Acar ◽  
Zahide nal ◽  
Rukiye Hasgul ◽  
Serpil Erdogan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Caffeic Acid ◽  
Royal Jelly ◽  
Caffeic Acid Phenethyl Ester ◽  
Preliminary Study

Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity

2002 ◽  
Vol 175 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Yun Seon Song ◽  
Eun-Hee Park ◽  
Gang Min Hur ◽  
Young Sue Ryu ◽  
Yong Sup Lee ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nitric Oxide ◽  
Enzyme Activity ◽  
Nitric Oxide Synthase ◽  
Caffeic Acid ◽  
Caffeic Acid Phenethyl Ester ◽  
Oxide Synthase

scholarly journals The impact of caffeic acid phenethyl ester, chrysin and ethanolic extracts of propolis on PLD1 gene expression in AGS cell line

2019 ◽  
Vol 8 (4) ◽  
pp. 308-313 ◽  
Author(s):  
Hamideh Jafari-Ghahfarokhi ◽  
Ali Jazaeri ◽  
Nematallah Amini-Sarteshnizi ◽  
Hossein Teimori
Keyword(s):  
Gene Expression ◽  
Cell Line ◽  
Caffeic Acid ◽  
Mrna Level ◽  
Caffeic Acid Phenethyl Ester ◽  
Control Group ◽  
Dependent Manner ◽  
Ags Cells ◽  
Ags Cell Line ◽  
The Impact

Introduction: Up-regulation of phospholipase D (PLD) is functionally related to tumorigenesis and oncogenic signals. Chrysin, caffeic acid phenethyl ester (CAPE) and ethanolic extract of propolis (EEP) are three safe compounds which have been shown to possess antiproliferative, antioxidant, anti-inflammatory and antineoplastic properties. In this study, the effects of these three compounds on PLD1 gene expression were examined in AGS cell line. Methods: After determining the appropriate concentrations of EEP, CAPE, and chrysin, AGS cells were cultured in mediums with proper ratios of the compounds. AGS cells were maintained in exponential growth and the culture mediums refreshed every other day. Finally, after extracting total RNA from AGS cells, real-time PCR was performed to evaluate the mRNA expression of PLD1 in the presence of each compound. Results: CAPE decreased the mRNA level of PLD1 gene in a dose-dependent manner. A solution with 30 μM concentration of CAPE was the effective dose in comparison to control group as well as 15 and 20 μM concentrations of the compound, whereas no changes were observed in the presence of EEP and chrysin. Conclusion: Taken together, the results of the study indicated that CAPE might exert its anti-neoplastic effect by targeting PLD1 expression in AGS cell line.

Cytotoxic activities of 4 natural products – carnosic acid, xanthohumol, caffeic acid phenethyl ester and (-) eburnamonine

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
DT Nga ◽  
QH Juan ◽  
KE Kyung ◽  
T Batmunkh ◽  
SJ Yeon ◽  
...  
Keyword(s):  
Natural Products ◽  
Caffeic Acid ◽  
Caffeic Acid Phenethyl Ester ◽  
Carnosic Acid ◽  
Cytotoxic Activities

Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1

2017 ◽  
Vol 23 (18) ◽  
Author(s):  
Valeria Pittala ◽  
Luca Vanella ◽  
Loredana Salerno ◽  
Claudia Di Giacomo ◽  
Rosaria Acquaviva ◽  
...  
Keyword(s):  
Caffeic Acid ◽  
Heme Oxygenase ◽  
Caffeic Acid Phenethyl Ester ◽  
Heme Oxygenase 1

scholarly journals Determination of antioxidant activity and phenolic compounds for basic standardization of Turkish propolis

2021 ◽  
Vol 64 (1) ◽  
Author(s):  
Aslı Özkök ◽  
Merve Keskin ◽  
Aslı Elif Tanuğur Samancı ◽  
Elif Yorulmaz Önder ◽  
Çiğdem Takma
Keyword(s):  
Antioxidant Capacity ◽  
Caffeic Acid ◽  
Caffeic Acid Phenethyl Ester ◽  
Total Phenolic ◽  
Scaling Analysis ◽  
Flavonoid Content ◽  
Multidimensional Scaling Analysis ◽  
Flavonoid Quercetin ◽  
Phenolic And Flavonoid

AbstractThis study aimed to determine the standard amount of antioxidant content and compounds of the propolis for the standardization of propolis. For this purpose, the total flavonoids, total phenolic, CUPRAC antioxidant capacity content and the diversity of phenolic and flavonoid components of these propolis samples were found by HPLC determined at the 23 propolis samples which were collected different regions of Turkey. Beside that, the similarities and differences of these 23 provinces to each other according to their antioxidant capacities were investigated by multidimensional scaling analysis. The total flavonoid content in the propolis samples were determined between 21.28 and 152.56 mg CE/g. The total phenolic content in the propolis samples was found between 34.53 mg and 259.4 mg GAE/g. CUPRAC antioxidant capacity of the propolis samples and antioxidant range was found from 95.35 to 710.43 mg TE/g. Also, 4 flavonoid [Quercetin (min.1.12–max.4.14 mg/g), Galangin (min.0.72–max.40.79 mg/g), Apigenin (min.1.07–max.17.35 mg/g), Pinocembrin (min.1.32–max.39.92 mg/g] and 6 phenolic acid [Caffeic acid (min.1.20–max.7.6 mg/g), p-Coumaric acid (min.1.26–max.4.47 mg/g), trans-Ferulic acid (min.1.28–max.4.92 mg/g), Protocatechuic acid (1.78 mg/g), trans-Cinnamic acid (min.1.05–max.3.83 mg/g), Caffeic Acid Phenethyl Ester (CAPE) (min.1.41–max.30.15 mg/g)] components were detected as mg/g, in different ratios in propolis samples collected from different regions. The feature of this study, so far, is to have the maximum number of samples representing the Turkish propolis, and so is thought to help to national and international propolis standard workings.

Royal jelly may improve sperm characteristics during preservation of rooster semen: Gene expression of antioxidant enzymes

2021 ◽  
Author(s):  
Atefeh Hadavand Mirzaei ◽  
Hamid Deldar ◽  
Zarbakht Ansari Pirsaraei ◽  
Bahram Shohreh
Keyword(s):  
Gene Expression ◽  
Antioxidant Enzymes ◽  
Royal Jelly ◽  
Sperm Characteristics

Root Cementum May Modulate Gene Expression During Periodontal Regeneration: A Preliminary Study in Humans

2008 ◽  
Vol 79 (2) ◽  
pp. 323-331 ◽  
Author(s):  
Patricia F. Gonçalves ◽  
Liana L. Lima ◽  
Enilson A. Sallum ◽  
Márcio Z. Casati ◽  
Francisco H. Nociti
Keyword(s):  
Gene Expression ◽  
Periodontal Regeneration ◽  
Preliminary Study
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