scholarly journals The Fascio Effect: Biotin and Sleep

2016 ◽  
Vol 8 (3) ◽  
pp. 22
Author(s):  
Kou Hayakawa ◽  
Takeaki Nagamine
Keyword(s):  
Breast Milk ◽  
Lipoic Acid ◽  
Hormone Receptors ◽  
Bovine Milk ◽  
Human Breast Milk ◽  
Thioctic Acid ◽  
Human Breast ◽  
Membrane Biosynthesis

<p class="1Body">An Italian maxim says “I bambini che dormono tanto crescono bene”, and the English maxim also says that “All children need to sleep in order to grow and develop”. In this review, we would like to demonstrate the truth of this proverb about sleep together with biotin (vitamin H) and lipoic acid (thioctic acid). Recently, we have found that D-biotin regulates the membrane biosynthesis in the cells. Previously, we have found that purified biotin-recycling enzyme biotinidase is also able to hydrolyze enkephalin and neuro-peptides. Thus, biotin state and sleep should be strongly linked to each other. In this report, we have investigated the expression of hormone receptors in some diseases using the new proteomics of protein-direct-microsequencing-deciphering (PDMD) method, and have indicated that having adequate sleep and nutrition is important to for healthy immunological and mental conditions in humans. It is also summarized that human breast milk is superior to bovine milk for human healthy babies to sleep and grow well.</p>

scholarly journals Nano-HPLC-HRMS Analysis to Evaluate Leptin Level in Milk Samples: A Pilot Study

2020 ◽  
Vol 10 (17) ◽  
pp. 6135
Author(s):  
Federica Dal Bello ◽  
Enrica Mecarelli ◽  
Daniela Gastaldi ◽  
Francesco Savino ◽  
Claudio Medana
Keyword(s):  
Pilot Study ◽  
Breast Milk ◽  
Infant Formula ◽  
Analytical Method ◽  
Critical Role ◽  
Bovine Milk ◽  
Human Breast Milk ◽  
Human Breast ◽  
Milk Samples ◽  
Limit Of Quantitation

Leptin is a 16 kDa lipophilic protein hormone secreted by adipocytes and its most significant function is to inform the brain with negative feedback that regulates food intake. Recently the protein found in human breast milk was related to breast feeding and onset of obesity, and the evidence of a low probability to develop pediatric obesity in children fed with breast milk was also confirmed. Since leptin could have a critical role, its quantitation both in human breast, bovine milk and in infant formula products is interesting. For this reason, we developed an analytical method based on immunoaffinity purification followed by an analysis with nano-High Pressure Liquid Chromatography coupled with High Resolution Mass Spectrometry analyzer (nano-HPLC-HRMS) to identify and quantify leptin in milk samples and performed a pilot study using samples of human breast milk, bovine milk and infant formulas. With an obtained lower limit of quantitation (LLOQ) of 100 ng mL−1 we quantified leptin in human breast milk finding an average of 6.70 ng mL−1. Our results show that leptin was under LLOQ both in bovine milk and in infant formula products. In conclusion, the developed analytical method here described was suitable to quantify leptin in milk samples with a good sensitivity and selectivity, and without the use of radioactive reagents.

Comparative Studies of Manganese Binding in Human Breast Milk, Bovine Milk and Infant Formula

1982 ◽  
Vol 112 (4) ◽  
pp. 642-651 ◽  
Author(s):  
Wai-Yee Chan ◽  
James M. Bates ◽  
Owen M. Rennert
Keyword(s):  
Breast Milk ◽  
Infant Formula ◽  
Comparative Studies ◽  
Bovine Milk ◽  
Human Breast Milk ◽  
Human Breast

scholarly journals Metabolomic Approaches to Explore Chemical Diversity of Human Breast-Milk, Formula Milk and Bovine Milk

2016 ◽  
Vol 17 (12) ◽  
pp. 2128 ◽  
Author(s):  
Linxi Qian ◽  
Aihua Zhao ◽  
Yinan Zhang ◽  
Tianlu Chen ◽  
Steven Zeisel ◽  
...  
Keyword(s):  
Breast Milk ◽  
Bovine Milk ◽  
Chemical Diversity ◽  
Milk Formula ◽  
Human Breast Milk ◽  
Human Breast ◽  
Formula Milk

Cariogenicity and Acidogenicity of Human Milk, Plain and Sweetened Bovine Milk: An In Vitro Study

2010 ◽  
Vol 34 (3) ◽  
pp. 239-247 ◽  
Author(s):  
A Prabhakar ◽  
Ameet Kurthukoti ◽  
Pranjali Gupta
Keyword(s):  
Breast Milk ◽  
Buffer Capacity ◽  
Bovine Milk ◽  
In Vitro Study ◽  
Human Breast Milk ◽  
Human Breast ◽  
Carious Lesions ◽  
Caries Model ◽  
Natural Milk

The objective of the present study was to determine the acidogenicity and cariogenicity of human breast milk and plain and sweetened packaged bovine milk. Study Design: First all milk specimens were inoculated with a cariogenic strain of Streptococcus mutans(SM). The culture pH and number of colony forming units (cfus) was assessed. Second, the buffer capacity of all milk specimens was evaluated by mixing with acid. Finally, enamel windows were created on extracted primary maxillary incisors and colonized with SM. Enamel demineralization and caries progression were assessed visually, histologically, and radiographically at the end of twelve weeks. Results: Plain and sweetened packaged bovine milk (BM) supported greater bacterial growth and caused more fermentation than human breast milk (HBM). The buffer capacity values for plain and sweetened bovine milk were highest;HBM, however, had poor buffering capacity. The progression of the carious lesions into the dentin was most severe for the sweetened bovine milk. Conclusions: HBM and plain bovine milk are relatively cariogenic in an in vitro caries model in the absence of saliva. However, supplementation with sugar exponentially enhances the cariogenic potential of the natural milk.

Organohalogen compounds in human breast milk from Republic of Buryatia, Russia

2007 ◽  
Vol 146 (1) ◽  
pp. 225-232 ◽  
Author(s):  
Oyuna V. Tsydenova ◽  
Agus Sudaryanto ◽  
Natsuko Kajiwara ◽  
Tatsuya Kunisue ◽  
Valeriy B. Batoev ◽  
...  
Keyword(s):  
Breast Milk ◽  
Human Breast Milk ◽  
Human Breast ◽  
Organohalogen Compounds
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