scholarly journals Non-HDL Cholesterol as a Predictor of Carotid Atherosclerosis in the Elderly

2005 ◽  
Vol 12 (3) ◽  
pp. 143-148 ◽  
Author(s):  
Ryuichi Kawamoto ◽  
Yuichiro Oka ◽  
Hitomi Tomita ◽  
Akihiro Kodama
Keyword(s):  
Carotid Atherosclerosis ◽  
Hdl Cholesterol ◽  
The Elderly

Association between triglyceride/HDL cholesterol ratio and carotid atherosclerosis in postmenopausal middle-aged women

2016 ◽  
Vol 63 (7) ◽  
pp. 327-332
Author(s):  
Walter Masson ◽  
Daniel Siniawski ◽  
Martín Lobo ◽  
Graciela Molinero ◽  
Melina Huerín
Keyword(s):  
Carotid Atherosclerosis ◽  
Hdl Cholesterol ◽  
Middle Aged ◽  
Cholesterol Ratio

Correlation between sarcopenia and atherosclerosis/cardiovascular risk factors in the elderly

2020 ◽  
Vol 30 (Supplement_2) ◽  
Author(s):  
A Sousa-Coelho ◽  
M Botelho ◽  
C Guerreiro ◽  
S Pais
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Muscle Strength ◽  
Total Cholesterol ◽  
Muscle Function ◽  
Hdl Cholesterol ◽  
The Elderly ◽  
Cholesterol Ratio ◽  
Cholesterol Levels ◽  
Risk Of Falls

Abstract Introduction Sarcopenia is the age-related loss of skeletal muscle mass, strength and function. Uncontrolled diabetes, obesity, chronic inflammation and lipid abnormalities, cause decreases in muscle strength, which contributes to disease-related morbidity. Objectives The main goal of this study was to correlate the prevalence of sarcopenia with atherosclerosis and cardiovascular risk factors, mainly estimated by cholesterol, triglycerides, C-reactive protein (CRP) and HbA1c levels, in the elderly. Methodology A quantitative observational cross-sectional study was performed in a convenience sample of individuals aged over 60 years old recruited non-randomly. Main study variables were body composition (seca® mBCA515), muscle strength (peak torque, Humac NORM isokinetic dynamometer), risk of falls (TUG test), muscle function (LEFS) and lipids, inflammation and glycaemic profile (cobas b101-Roche®). Results Total cholesterol levels fully correlated with LDL and non-HDL cholesterol, and partially with triglycerides, but not with HDL-cholesterol levels, HbA1c, or BMI. LDL-cholesterol levels did not correlate with muscle mass (free-fat mass (%)), strength, function, or risk of falls. Similarly, HDL-cholesterol levels did not correlate with muscle function or falls risk. Cholesterol ratio, obtained by dividing total cholesterol by HDL-cholesterol levels, was significantly higher in individuals with CRP levels above 3 mg/L. Interestingly, when compared to normal values, individuals with triglycerides above 150 mg/dL showed a statistically significant decrease in muscle strength. Conclusion From the biochemical measured parameters, our data showed that only high triglycerides levels positively correlated with sarcopenia risk, demonstrated by reduced muscle strength. While cholesterol ratio positively correlated with increased inflammation, blood cholesterol levels seem to be independent factors regarding sarcopenia prevalence.

PREVALENCE AND CHARACTERISTICS OF METABOLIC SYNDROME PATIENTS IN CIBEBER VILLAGE CIMAHI INDONESIA

2021 ◽  
Vol 1 (Volume 1 No 1) ◽  
pp. 27-37
Author(s):  
Iis Inayati Rakhmat ◽  
Hadi Jusuf ◽  
Sinta Rachmanita
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Pap Test ◽  
Serum Triglyceride ◽  
Hdl Cholesterol ◽  
The Elderly ◽  
Cross Sectional ◽  
Descriptive Research ◽  
Cholesterol Levels ◽  
Cross Sectional Design

Metabolic syndrome is a health problem that often occurs among populations in Indonesia. Data on the characteristics of patients with metabolic syndrome is still very limited, despite the importance of cardiovascular disease prevention. The study aims to explain the prevalence and characteristics of patients with metabolic syndrome in Indonesia. The research methodology used descriptive research using a cross-sectional design. The number of respondents was seven men and 34 women, counted by consecutive sampling. The data was collected from the SQ-FFQ questionnaire and calculating the DQI-I score, analyzing physical activity through the GPAQ questionnaire converted into METs, measuring blood pressure, taking blood, measuring waist circumference, measuring fasting blood sugar. Through enzymatic tests, Serum triglyceride levels through the enzymatic colorimetric GPO-PAP test and HDL cholesterol levels were measured by the CHODPAP method. The results showed that the prevalence of SM was 20.45%, and the majority were women. The largest age group were the elderly. Most cases of metabolic syndrome have three components, with the largest components being central obesity (100%) and blood pressure (88.89%). Most categories of activity were moderate, and diet quality was low. All metabolic syndrome patients in this study were found not to smoke and not to consume alcohol. Based on these results, it can be concluded that SM incidence was high. Further research is needed regarding the relationship between acquired risk factors and metabolic syndrome.

scholarly journals New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains

2013 ◽  
Vol 45 (8) ◽  
pp. 332-342 ◽  
Author(s):  
Jessica S. Rowlan ◽  
Zhimin Zhang ◽  
Qian Wang ◽  
Yan Fang ◽  
Weibin Shi
Keyword(s):  
Apolipoprotein E ◽  
Quantitative Trait ◽  
Carotid Atherosclerosis ◽  
Plasma Lipid ◽  
Hdl Cholesterol ◽  
Carotid Bifurcation ◽  
Mouse Strains ◽  
Entire Genome ◽  
Significant Qtls ◽  
Trait Locus

Carotid atherosclerosis is the primary cause of ischemic stroke. To identify genetic factors contributing to carotid atherosclerosis, we performed quantitative trait locus (QTL) analysis using female mice derived from an intercross between C57BL/6J (B6) and BALB/cJ (BALB) apolipoprotein E ( Apoe−/−) mice. We started 266 F2 mice on a Western diet at 6 wk of age and fed them the diet for 12 wk. Atherosclerotic lesions in the left carotid bifurcation and plasma lipid levels were measured. We genotyped 130 microsatellite markers across the entire genome. Three significant QTLs, Cath1 on chromosome (Chr) 12, Cath2 on Chr5, and Cath3 on Chr13, and four suggestive QTLs on Chr6, Chr9, Chr17, and Chr18 were identified for carotid lesions. The Chr6 locus replicated a suggestive QTL and was named Cath4. Six QTLs for HDL, three QTLs for non-HDL cholesterol, and three QTLs for triglyceride were found. Of these, a significant QTL for non-HDL on Chr1 at 60.3 cM, named Nhdl13, and a suggestive QTL for HDL on ChrX were new. A significant locus for HDL ( Hdlq5) was overlapping with a suggestive locus for carotid lesions on Chr9. A significant correlation between carotid lesion sizes and HDL cholesterol levels was observed in the F2 population ( R = −0.153, P = 0.0133). Thus, we have identified several new QTLs for carotid atherosclerosis and the locus on Chr9 may exert effect through interactions with HDL.

The relationship between nonalcoholic hepatic steatosis and carotid atherosclerosis at the elderly

2016 ◽  
Vol 252 ◽  
pp. e195
Author(s):  
A. Capisizu ◽  
A. Zamfirescu ◽  
R. Dascalescu ◽  
O. Stanciu ◽  
S.M. Aurelian
Keyword(s):  
Hepatic Steatosis ◽  
Carotid Atherosclerosis ◽  
The Elderly ◽  
Nonalcoholic Hepatic Steatosis ◽  
The Relationship

SOCIAL LINKAGES TO BIOLOGICAL MARKERS OF HEALTH AMONG THE ELDERLY

2003 ◽  
Vol 35 (3) ◽  
pp. 433-453 ◽  
Author(s):  
MAXINE WEINSTEIN ◽  
NOREEN GOLDMAN ◽  
ALLISON HEDLEY ◽  
LIN YU-HSUAN ◽  
TERESA SEEMAN
Keyword(s):  
Biological Markers ◽  
Lower Risk ◽  
Allostatic Load ◽  
Cumulative Risk ◽  
Hdl Cholesterol ◽  
Well Being ◽  
The Elderly ◽  
The United States ◽  
Population Based ◽  
Life Challenge

The social environment and exposure to life challenge affect a person's physical and emotional well-being. The present research uses a population-based study of the elderly in Taiwan to elaborate the cumulative physiological costs – as reflected in biological markers of risk factors known to have adverse consequences for health – of challenge and unfavourable position in social hierarchies and networks. Overall, biological markers of risk among the elderly are similar in Taiwan and the United States. However, male and female Taiwanese elderly are at lower risk for illness associated with indicators of DHEA-S, while women are at higher risk for illness associated with elevated blood pressure, and men at lower risk for illness associated with total/HDL cholesterol, and glycosylated haemoglobin. There are strong and statistically significant effects of position in social hierarchy (education) and challenge (recent widowhood and a perception of high demands) on an index of cumulative risk (allostatic load). Membership in social networks and participation in social activities have expected, but not statistically discernible, effects.

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