scholarly journals Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review

2017 ◽  
Vol 24 (3) ◽  
pp. 208-226 ◽  
Author(s):  
Muhammad Aziz ◽  
Shozab S. Ali ◽  
Sankalp Das ◽  
Adnan Younus ◽  
Rehan Malik ◽  
...  
2020 ◽  
Author(s):  
ling wang ◽  
Feng Jin

Abstract Background : To assess the association of sleep duration and quality with the risk of preterm birth. Methods : Relevant studies were retrieved from the PubMed and Web of Science databases up to September 30, 2018. The reference lists of the retrieved articles were reviewed. Random effects models were applied to estimate summarized relative risks (RRs) and 95% confidence intervals (CIs). Results : Ten identified studies (nine cohort studies and one case-controlled study) examined the associations of sleep duration and quality with the risk of preterm birth. As compared with women with the longest sleep duration, the summary RR was 1.23 (95% CI = 1.01–1.50) for women with the shortest sleep duration, with moderate between-study heterogeneity ( I 2 = 57.4%). Additionally, as compared with women with good sleep quality, the summary RR was 1.54 (95% CI = 1.18–2.01) for women with poor sleep quality (Pittsburgh Sleep Quality Index > 5), with high between-study heterogeneity ( I 2 = 76.7%). Funnel plots as well as the Egger’s and Begg’s tests revealed no evidence of publication bias. Conclusions : This systematic review and meta-analysis revealed that short sleep duration and poor sleep quality may be associated with an increased risk of preterm birth. Further subgroup analyses are warranted to test the robustness of these findings as well as to identify potential sources of heterogeneity.


2018 ◽  
Vol 56 (9) ◽  
pp. 1432-1442 ◽  
Author(s):  
Vishal Gohel ◽  
Judith A. Jones ◽  
Carolyn J. Wehler

Abstract Background: The purpose of this systematic review is to summarize the literature examining associations between salivary biomarkers and cardiovascular disease (CVD) status. Contents: An advanced search was conducted using MeSH terms related to salivary biomarkers and CVD, and entered into the PubMed, Web of Science, and Google Scholar search databases. Four hundred and thirty-three records were narrowed to 22 accepted articles. Included titles were assessed for quality using the Newcastle-Ottawa scale, and ranked into categories of low, moderate, or high. Summary: A total of 40 salivary biomarkers were analyzed among accepted articles. The most studied markers were salivary creatine kinase isoform MB, C-reactive protein (CRP), matrix metalloproteinase-9, troponin I, myeloperoxidase, myoglobin, and brain natriuretic peptide. Salivary CRP provided the most consistent trends. Statistically significant increases of salivary CRP were present with CVD in every study that analyzed it. The remaining six markers demonstrated varying patterns. Outlook: Existing studies provide insufficient data to draw definitive conclusions. Current research shows that there is an association between some salivary biomarkers and CVD, but the details of existing studies are conflicting. Despite inconclusive results, the diagnostic potential of saliva shows promise as a non-invasive means of cardiovascular risk assessment.


2019 ◽  
Vol 8 (12) ◽  
pp. 2156 ◽  
Author(s):  
Jacobo Á. Rubio-Arias ◽  
Raquel Rodríguez-Fernández ◽  
Luis Andreu ◽  
Luis M. Martínez-Aranda ◽  
Alejandro Martínez-Rodriguez ◽  
...  

Sarcopenia is an age-related condition. However, the prevalence of sarcopenia may increase due to a range of other factors, such as sleep quality/duration. Therefore, the aim of the study is to conduct a systematic review with meta-analysis to determine the prevalence of sarcopenia in older adults based on their self-reported sleep duration. Methods: Three electronic databases were used—PubMed-Medline, Web of Science, and Cochrane Library. We included studies that measured the prevalence of sarcopenia, divided according to sleep quality and excluded studies (a) involving populations with neuromuscular pathologies, (b) not showing prevalence values (cases/control) on sarcopenia, and (c) not including classificatory models to determine sleep quality. Results: high prevalence values in older adults with both long and short sleep duration were shown. However, prevalence values were higher in those with inadequate sleep (<6–8 h or low efficiency) (OR 0.76; 95% CI (0.70–0.83); Q = 1.446; p = 0.695; test for overall effect, Z = 6.01, p < 0.00001). Likewise, higher prevalence levels were shown in men (OR 1.61; 95% CI (0.82–3.16); Q = 11.80; p = 0.0189) compared to women (OR 0.77; 95% CI (0.29–2.03); Q = 21.35; p = 0.0003). Therefore, the prevalence of sarcopenia appears to be associated with sleep quality, with higher prevalence values in older adults who have inadequate sleep.


BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e039655
Author(s):  
Christopher Gerdung ◽  
Sara Rodriguez-Lopez ◽  
Stefan Palkowski ◽  
Diana Keto-Lambert ◽  
Meghan Sebastianski ◽  
...  

IntroductionObstructive sleep apnoea (OSA) is not only common within paediatrics but is associated with critical childhood metabolic morbidity such as obesity, cardiovascular disease and glucose tolerance impairment. Increasing evidence suggests an association between childhood OSA and metabolic syndrome such as markers of cardiovascular disease, systemic hypertension, glucose intoleranceand increased lipid profile. Recent studies have targeted changes in metabolic markers in children using non-invasive ventilation (NIV) but no systematic reviews are available to summarise this emerging evidence. The purpose of this systematic review is to provide systematic synthesis of the evidence on the effect of NIV use on metabolic markers in children with OSA.Methods and analysisA systematic search of electronic databases and grey literature will include paediatric interventional studies (random controlled trials, cohort studies) with and without a comparison group. Two reviewers will independently undertake the two step process of title/abstract and full-text screening. Data will be extracted and assessed, with aggregate data being reported. When the data allow, meta-analysis will be performed.Ethics and disseminationThere are no ethical concerns with this systematic review, as data have previously been published. This review will inform clinicians taking care of children with OSA and obesity/metabolic syndrome about the potential effects of NIV therapies on metabolic markers and has the potential to change the approach to childhood OSA and obesity. Results of this systematic review will be submitted for dissemination in abstract and manuscript form.


BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e018585 ◽  
Author(s):  
Marlot Kruisbrink ◽  
Wendy Robertson ◽  
Chen Ji ◽  
Michelle A Miller ◽  
Johanna M Geleijnse ◽  
...  

ObjectivesTo assess the longitudinal evidence of the relationships between sleep disturbances (of quantity and quality) and dyslipidaemia in the general population and to quantify such relationships.SettingSystematic review and meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.MethodsWe performed a systematic search of PubMed and Embase (up to 9 September 2017), complemented with manual searches, of prospective population studies describing the association between sleep duration and quality and the incidence of dyslipidaemias. Relative risks (95% CIs) were extracted and pooled using a random effects model. Subgroup analyses by lipid type were performed. Heterogeneity and publication bias were also assessed. Quality was assessed with Downs and Black score.ParticipantsStudies were included if they were prospective, had measured sleep quantity and/or quality at baseline and either incident cases of dyslipidaemia or changes in blood lipid fractions assessed prospectively.Primary outcome measuresIncidence of dyslipidaemia and changes in lipid fractions. Dyslipidaemia was defined as a high total cholesterol, triglycerides, low-density lipoprotein cholesterol or low high-density lipoprotein cholesterol compared with the reference group.ResultsThirteen studies were identified (eight using sleep duration, four sleep quality and one both). There was heterogeneity in the sleep quality aspects and types of lipids assessed. Classification of sleep duration (per hour/groups) also varied widely. In the pooled analysis of sleep duration (6 studies, 16 cohort samples; 30 033 participants; follow-up 2.6–10 years), short sleep was associated with a risk of 1.01 (95% CI 0.93 to 1.10) of developing dyslipidaemia, with moderate heterogeneity (I2=56%, P=0.003) and publication bias (P=0.035). Long sleep was associated with a risk of 0.98 (95% CI 0.87 to 1.10) for dyslipidaemia, with heterogeneity (I2=63%, P<0.001) and no significant publication bias (P=0.248).ConclusionThe present analysis was unable to find supportive evidence of a significant relationship between sleep duration and the development of dyslipidaemia. However, heterogeneity and small number of studies limit the interpretation.PROSPERO registration numberCRD42016045242.


2009 ◽  
Vol 49 (2-3) ◽  
pp. 135-141 ◽  
Author(s):  
Etsuji Suzuki ◽  
Takashi Yorifuji ◽  
Kazumune Ueshima ◽  
Soshi Takao ◽  
Masumi Sugiyama ◽  
...  

2021 ◽  
Vol 10 (Supplement_1) ◽  
Author(s):  
PN Fountoulakis ◽  
A Terzoudi ◽  
D Tsiptsios ◽  
AS Triantafyllis ◽  
A Matziridis ◽  
...  

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Sleep disorders are an emerging and modifiable risk factor for cardiovascular disease (CVD). Purpose The aim of our study was to investigate potential associations between sleep insufficiency and incident CVD. Methods In this cross-sectional study, 957 participants, (mean age 49.62 ± 14.79) from the region of Thrace, Greece were enrolled and classified into three groups [short (&lt;6 h), normal (6-8 h) and long (&gt;8 h) sleep duration]. CVD was assessed by a positive response to the following questions: "Have you been told by a doctor that you have had a heart attack or angina (chest pain or exertion that is relieved by medication)?" or "Have you been told by a doctor that you have had a stroke?". Participants’ sleep quality was estimated with the Epworth Sleepiness Scale, Athens Insomnia Scale, Pittsburgh Sleep Quality Index, and Berlin Questionnaire. Results The overall prevalence of CVD was 9.5%. The population with CVD exhibited reduced sleep duration and efficiency reduced by 33 min and 10%, respectively. After adjusting for all possible cofounders, short sleep duration was 3.07-times more frequent in patients with CVD and sleep duration of less than 5:33 hours could be a potential risk factor for CVD, especially among females. Additionally, CVD was significantly associated with excessive increased daytime sleepiness, insomnia, poor sleep quality and increased risk of obstructive sleep apnea. Conclusion(s): Our study depicts a strong correlation of sleep insufficiency with CVD and promotes early pharmacological or cognitive behavioral interventions in order to protect cardiovascular health. Abstract Figure. Results


2020 ◽  
Author(s):  
Teresa Arora ◽  
Asma Alamoodi ◽  
Ian Grey ◽  
Linda Östlundh ◽  
Omar M. Omar ◽  
...  

Abstract Background: Mental resilience has emerged as a recent focus within the context of positive psychology. Resilience is a potentially modifiable construct. Some preliminary evidence from experimental studies as well as clinical populations has indicated that sleep may be related to mental resilience, but little is known about this relationship in healthy populations. Sleep is a complex with multi-factorial outcome, although the majority of research effort has focused on sleep duration and sleep quality. Our systematic review and meta-analysis will identify original research data from observational studies to assess if sleep duration and/or sleep quality is associated with levels of psychological resilience amongst healthy children, adolescents and adults. We hypothesize that there will be a positive association between sleep duration/quality and mental resilience across all age groups. Methods: A comprehensive, systematic search for literature will be conducted in June 2020 (LÖ), covering a total of eight academic databases (PubMed, Embase, PsycInfo, PsycArticles, CINAHL, Scopus, Web of Science and Academic Search Complete). Sources for grey materials will also be included and experts in the field will also be contacted for inclusion of unpublished data. PubMed and PubMed’s MeSH terms were used to develop the search strategy and systematically identify relevant search terms. Two authors (IG & AA) will screen the articles independently, and a third researcher (TA) will resolve discrepancies. The primary outcome is mental/psychological resilience. The systematic review will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Discussion: The results of our systematic review and meta-analysis are intended to be published in an appropriate scientific peer-reviewed journal and will be made publicly available. The findings from our project are envisioned to inform and educate the public as well as healthcare and education systems, globally. Our systematic review protocol has been peer-reviewed and is currently registered in the international database, PROSPERO.Systematic review registration: CRD42020191119 (submitted on 2 July 2020).


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