Evaluation of Properties, Pathogens, and Mortality-Related Risk Factors of Nosocomial Infections in Pediatric Cardiovascular Surgery Intensive Care Unit

Objectives: Healthcare-associated infections are the most common problem in intensive care unit worldwide. Children with congenital heart diseases have many complications such as developmental problems, respiratory tract infections, endocarditis,pneumonia and after long-term hospital and intensive care stays and surgeries patients become vulnerable to healthcare-associated infections. Patients and Methods: The study presents the frequency of infection, microorganisms in patients hospitalized at SBÜ Koşuyolu High Spesialization Research and Training Hospital pediatric cardiovascular surgery intensive care unit between 2016-2020. Results: One hundred-eight HAI episodes were seen in 83 of 1920 patients hospitalized in pediatric cardiovascular surgery intensive care unit between 2016-2020.HAI rates varied between 4.8% and 7.77%. In the 5-year period,a total of 118 different microorganisms were detected.Among all microorganisms, Candida species (n: 43, 36.4%) ranked first. central line-associated bloodstream infections (CLABSI) 53 (49%), ventilator-associated pneumonia (VAP)40 (37%), surgical site infection (SSI) 8 (6.5%), catheter -associated urinary tract infection (CAUTI) 7 (6%) Conclusion: Healthcare-associated infections are require special attention in pediatric cardiovascular intensive care units. In order to prevent, innovations such as bundle applications should be implemented as well as personnel training.

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Clinical characteristics, evolution, and treatment-related risk factors for mortality among immunosuppressed patients with influenza A (H1N1) virus admitted to the intensive care unit

Journal of Critical Care ◽

10.1016/j.jcrc.2018.08.017 ◽

2018 ◽

Vol 48 ◽

pp. 172-177 ◽

Cited By ~ 8

Author(s):

José Garnacho-Montero ◽

Cristina León-Moya ◽

Antonio Gutiérrez-Pizarraya ◽

Angel Arenzana-Seisdedos ◽

Loreto Vidaur ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Influenza A ◽

Clinical Characteristics ◽

H1n1 Virus ◽

Related Risk ◽

Influenza A H1n1 ◽

Immunosuppressed Patients

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Effect of Nosocomial Infections Due to Antibiotic-Resistant Organisms on Length of Stay and Mortality in the Pediatric Intensive Care Unit

Infection Control and Hospital Epidemiology ◽

10.1086/512628 ◽

2007 ◽

Vol 28 (3) ◽

pp. 299-306 ◽

Cited By ~ 33

Author(s):

Elizabeth E. Foglia ◽

Victoria J. Fraser ◽

Alexis M. Elward

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Nosocomial Infections ◽

Univariate Analysis ◽

Pediatric Intensive Care ◽

Resistant Bacteria ◽

Antibiotic Resistant ◽

Risk Of Mortality ◽

The Mean

Objective.To determine the prevalence, risk factors, and outcomes of nosocomial infection due to antimicrobial resistant bacteria in patients treated in the pediatric intensive care unit (PICU).Design.Nested case-cohort study. Patient data were collected prospectively, and antimicrobial susceptibility data were abstracted retrospectively.Setting.A large pediatric teaching hospital.Patients.All PICU patients admitted from September 1, 1999, to September 1, 2001, unless they died within 24 hours after PICU admission, were 18 years old or older, or were neonatal intensive care unit patients receiving extracorporeal membrane oxygenation.Results.A total of 135 patients with more than 1 nosocomial bacterial infection were analyzed; 52% were male, 75% were white, the mean Pediatric Risk of Mortality score was 10.5, and the mean age was 3.5 years. Of these patients, 37 (27%) had nosocomial infections due to antibiotic-resistant organisms. In univariate analysis, transplantation (odds ratio [OR], 2.83 [95% confidence interval (CI), 1.05-7.66]) and preexisting lung disease (OR, 2.63 [95% CI, 1.18-5.88]) were associated with nosocomial infections due to antibiotic-resistant organisms. Age, Pediatric Risk of Mortality score at admission, length of hospital stay before infection, and other underlying conditions were not associated with infections due to antibiotic-resistant organisms. Patients infected with antibiotic-resistant organisms had greater mean PICU lengths of stay after infection, compared with patients infected with antibiotic-susceptible organisms (22.9 vs 12.8 days;P= .004), and higher crude mortality rates (OR, 2.40 [95% CI, 1.03-5.61]).Conclusions.Identifiable risk factors exist for nosocomial infections due to antibiotic-resistant organisms. In univariate analysis, infections due to antibiotic-resistant bacteria are associated with increased length of stay in the PICU after onset of infection and increased mortality.

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Nosocomial infections in the intensive care unit: Incidence, risk factors, outcome and associated pathogens in a public tertiary teaching hospital of Eastern India

Indian Journal of Critical Care Medicine ◽

10.4103/0972-5229.148633 ◽

2015 ◽

Vol 19 (1) ◽

pp. 14-20 ◽

Cited By ~ 42

Author(s):

Avijit Hazra ◽

Sugata Dasgupta ◽

Soumi Das ◽

Neeraj S. Chawan

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Teaching Hospital ◽

Nosocomial Infections ◽

Eastern India ◽

Tertiary Teaching ◽

Incidence Risk ◽

Tertiary Teaching Hospital

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Patients with Primary Immunodeficiencies in Pediatric Intensive Care Unit: Outcomes and Mortality-Related Risk Factors

Journal of Clinical Immunology ◽

10.1007/s10875-014-9994-6 ◽

2014 ◽

Vol 34 (3) ◽

pp. 309-315 ◽

Cited By ~ 7

Author(s):

Çağlar Ödek ◽

Tanıl Kendirli ◽

Figen Doğu ◽

Ayhan Yaman ◽

Göksel Vatansever ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Pediatric Intensive Care ◽

Primary Immunodeficiencies ◽

Related Risk

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Nosocomial infections and risk factors in intensive care unit of a university hospital

Journal of Clinical and Experimental Investigations ◽

10.5799/ahinjs.01.2015.03.0525 ◽

2015 ◽

Vol 6 (3) ◽

Cited By ~ 1

Author(s):

Zuhal Yesilbag ◽

Aslı Karadeniz ◽

Seniha Basaran ◽

Fatih Oner Kaya

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Nosocomial Infections ◽

University Hospital

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Nosocomial Infections in Neonatal Intensive Care Unit In Pediatric Assiut University Hospital: Incidence and Risk Factors

Journal of High Institute of Public Health ◽

10.21608/jhiph.2008.22498 ◽

2008 ◽

Vol 38 (Proceedings) ◽

pp. 33-48

Author(s):

Asmaa Soliman ◽

Eman Mohamed ◽

Kawthar Fadel ◽

Samia Mohamed ◽

Enas Daef

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Nosocomial Infections ◽

Neonatal Intensive Care ◽

University Hospital

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Catheter-associated urinary tract infection in a surgical intensive care unit

Vojnosanitetski pregled ◽

10.2298/vsp140624078m ◽

2015 ◽

Vol 72 (10) ◽

pp. 883-888 ◽

Cited By ~ 5

Author(s):

Jovan Mladenovic ◽

Milic Veljovic ◽

Ivo Udovicic ◽

Srdjan Lazic ◽

Zeljko Jadranin ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Urinary Tract Infection ◽

Intensive Care ◽

Urinary Tract ◽

Tract Infection ◽

Nosocomial Infections ◽

Surgical Intensive Care Unit ◽

Control Group ◽

Surgical Intensive Care

Background/Aim. Because patients in intensive care units usually have an urinary catheter, the risk of urinary tract infection for these patients is higher than in other patients. The aim of this study was to identify risk factors and causative microrganisms in patients with catheter-associated urinary tract infection (CAUTI) in the Surgical Intensive Care Unit (SICU) during a 6-year period. Methods. All data were collected during prospective surveillance conducted from 2006 to 2011 in the SICU, Military Medical Academy, Belgrade, Serbia. This case control study was performed in patients with nosocomial infections recorded during surveillance. The cases with CAUTIs were identified using the definition of the Center for Disease Control and Prevention. The control group consisted of patients with other nosocomial infections who did not fulfill criteria for CAUTIs according to case definition. Results. We surveyed 1,369 patients representing 13,761 patient days. There were a total of 226 patients with nosocomial infections in the SICU. Of these patients, 64 had CAUTIs as defined in this study, and 162 met the criteria for the control group. Multivariate logistic regression analysis identified two risk factors independently associated to CAUTIs: the duration of having an indwelling catheter (OR = 1.014; 95% CI 1.005-1.024; p = 0.003) and female gender (OR = 2.377; 95%CI 1.278-4.421; p = 0.006). Overall 71 pathogens were isolated from the urine culture of 64 patients with CAUTIs. Candida spp. (28.2%), Pseudomonas aeruginosa (18.3%) and Klebsiella spp. (15.5%) were the most frequently isolated microorganisms. Conclusions. The risk factors and causative microrganisms considering CAUTIs in the SICU must be considered in of planning CAUTIs prevention in this setting.

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