The Relationship Between Maternal Serum Visfatin Level And Hypertensive Disorders of Pregnancy

10.5580/1fcc ◽  
2011 ◽  
Vol 15 (1) ◽  
Keyword(s):  
Maternal Serum ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Visfatin Level ◽  
The Relationship

The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women

1998 ◽  
Vol 179 (4) ◽  
pp. 1032-1037 ◽  
Author(s):  
Gary M. Joffe ◽  
Joy R. Esterlitz ◽  
Richard J. Levine ◽  
John D. Clemens ◽  
Marian G. Ewell ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Abnormal Glucose Tolerance ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Nulliparous Women ◽  
The Relationship

The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women

1997 ◽  
Vol 176 (1) ◽  
pp. S104
Author(s):  
R.M. Catalano ◽  
B.M. Sibai ◽  
J. Clemens ◽  
G.M. Joffe ◽  
J. Esterlitz ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Abnormal Glucose Tolerance ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Nulliparous Women ◽  
The Relationship

scholarly journals Study of the serum uric acid level as a prognostic indicator in hypertensive disorders of pregnancy

2021 ◽  
Vol 10 (9) ◽  
pp. 3441
Author(s):  
Smitha Krishnegowda ◽  
G. Nita
Keyword(s):  
Uric Acid ◽  
Disease Severity ◽  
Serum Uric Acid ◽  
Mode Of Delivery ◽  
Prognostic Indicator ◽  
Maternal Serum ◽  
P Value ◽  
Chronic Hypertension ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders

Background: Abnormal uric acid levels in patients with preeclampsia and eclampsia affect both maternal and fetal outcome negatively. This study was done to know the alterations in these serum levels in comparison to normal pregnancy and also among various hypertensive disorders of pregnancies.Methods: Maternal serum uric acid levels were compared among cases and controls in relation to disease severity, mode of delivery, maternal outcome.Results: In group A (cases), 10 patients had raised uric acid levels, of which 5 were severe preeclampsia, 3 were eclampsia and 2 cases of chronic hypertension superimposed preeclampsia. P value is 0.001 (highly significant). Also serum uric acid is significantly elevated in hypertensive disorders of pregnancy compared with controls with a P value of 0.001.Conclusions: Significant correlation was observed between maternal serum uric acid, disease severity and maternal outcome. Our study concludes that uric acid can be considered as a sensitive prognostic indicator of severity in hypertensive disorders of pregnancy.

scholarly journals Sequential measurement of the neurosensory retina in hypertensive disorders of pregnancy: a model of microvascular injury in hypertensive emergency

2021 ◽  
Author(s):  
Robert J. Herman ◽  
Anshula Ambasta ◽  
R. Geoff Williams ◽  
Kelly B. Zarnke ◽  
Fiona E. Costello ◽  
...  
Keyword(s):  
De Novo ◽  
Clinical Laboratory ◽  
Normal Pregnancy ◽  
Macular Thickness ◽  
Chronic Hypertension ◽  
Hypertensive Disorders Of Pregnancy ◽  
Laboratory Findings ◽  
Response Data ◽  
Hypertensive Disorders ◽  
The Relationship

AbstractOptical coherence tomography of the eye suggests the retina thins in normal pregnancy. Our objectives were to confirm and extend these observations to women with hypertensive disorders of pregnancy (HDP). Maternal demographics, clinical/laboratory findings and measurements of macular thickness were repeatedly collected at gestational ages <20 weeks, 20-weeks to delivery, at delivery and postpartum. The primary outcome was the change in macular thickness from non-pregnant dimensions in women with incident HDP compared to non-hypertensive pregnant controls. Secondary outcomes were the relationship(s) between mean arterial pressure (MAP) and macular response. Data show macular thicknesses diminished at <20 weeks gestation in each of 27 pregnancies ending in HDP (mean 3.94 µm; 95% CI 4.66, 3.21) and 11 controls (mean 3.92 µm; 5.05, 2.79; P < 0.001 versus non-pregnant dimensions in both; P = 0.983 HDP versus controls). This thinning response continued to delivery in all controls and in 7 women with HDP superimposed on chronic hypertension. Macular thinning was lost after 20 weeks gestation in the other 20 women with HDP. MAP at loss of macular thinning in women without prior hypertension (n = 12) was identical to MAP at enrollment. However, mean MAP subsequently rose 19 mmHg (15, 22) leading to de novo HDP in all 12 women. Loss of thinning leading to a rise in MAP was also observed in 8 of 15 women with HDP superimposed on chronic hypertension. We conclude the macula thins in most women in early pregnancy. Those who lose this early macular thinning response often develop blood pressure elevations leading to HDP.

Depression, Antidepressants and Hypertensive Disorders of Pregnancy: A Systematic Review

2019 ◽  
Vol 14 (2) ◽  
pp. 102-108 ◽  
Author(s):  
Sabrina Youash ◽  
Verinder Sharma
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Gestational Hypertension ◽  
Research Question ◽  
Current Evidence ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertension In Pregnancy ◽  
Hypertensive Disorders ◽  
The Relationship ◽  
In Pregnancy

Background: Hypertensive disorders of pregnancy including gestational hypertension, preeclampsia and eclampsia are conditions that cause significant perinatal and maternal morbidity and mortality. </P><P> Objective: This is a systematic review of the current evidence examining the relationship between both depression and antidepressants on pregnancy-related hypertensive conditions. </P><P> Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, six databases were searched for articles published between January 1990 and December 2017 (PubMed, Embase, PsycINFO, Cochrane Database of Systematic Reviews, MEDLINE and ClinicalTrials. gov). Randomized control trials, cohort studies and case-control studies were included in this review. Studies that measured the following exposures were included: Antidepressant exposure or diagnosis of depression. Studies that measured the following outcomes were included: Gestational hypertension, preeclampsia or eclampsia. A combination of keywords, as well as Medical Subject Headings (MeSH) index terms, was used for three general categories: antidepressants, depression and hypertensive disorders of pregnancy. A total of 743 studies were identified and 711 were excluded based on relevance to the research question. Twenty studies were included in the final systematic review. </P><P> Results: Of the twenty relevant studies, ten specifically examined the relationship between depression and hypertension in pregnancy. Only two of these did not find a significant association. Of the ten studies that concentrated on antidepressant medications, all except one found an association with hypertension in pregnancy to varying degrees. </P><P> Conclusion: Review of the literature suggests a possible association between depression and antihypertensive medications with pregnancy-related hypertension, but further studies are needed.</P>

Maternal serum angiopoietin-2 at 11 to 13 weeks of gestation in hypertensive disorders of pregnancy

2009 ◽  
Vol 29 (9) ◽  
pp. 847-851 ◽  
Author(s):  
Ranjit Akolekar ◽  
Davide Casagrandi ◽  
Evdoxia Skyfta ◽  
Abubaker Abdalla Ahmed ◽  
Kypros H. Nicolaides
Keyword(s):  
Maternal Serum ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Angiopoietin 2

scholarly journals Frequent Placental SARS-CoV-2 in Patients with COVID-19-Associated Hypertensive Disorders of Pregnancy

2021 ◽  
pp. 1-11
Author(s):  
Marta Fabre ◽  
Pilar Calvo ◽  
Sara Ruiz-Martinez ◽  
Maria Peran ◽  
Daniel Oros ◽  
...  
Keyword(s):  
Viral Load ◽  
Gestational Hypertension ◽  
Group Versus ◽  
Control Group ◽  
Hypertensive Disorders Of Pregnancy ◽  
Rt Pcr ◽  
Third Trimester ◽  
Hypertensive Disorders ◽  
The Moment ◽  
The Relationship

<b><i>Introduction:</i></b> Studies described an increased frequency of hypertensive disorders of pregnancy (HDP) after a COVID-19 episode. There is limited evidence about SARS-CoV-2 viral load in placenta. This study aimed to investigate the relationship between SARS-CoV-2 viral load in the placenta and clinical development of HDP after COVID-19 throughout different periods of gestation. <b><i>Methods:</i></b> This is a case-control study in women with and without gestational hypertensive disorders after SARS-CoV-2 infection diagnosed by RT-PCR during pregnancy. Patients were matched by gestational age at the moment of COVID-19 diagnosis. We performed an analysis of SARS-CoV-2 RNA levels in placenta. <b><i>Results:</i></b> A total of 28 women were enrolled. Sixteen patients were diagnosed with COVID-19 during the third trimester and the remaining 12 patients in the other trimesters. Ten placentas (35.7%) were positive for SARS-CoV-2, 9 of them (9/14, 64.3%) belonged to the HDP group versus 1 (1/14, 7.2%) in the control group (<i>p</i> = 0.009). Those cases with the highest loads of viral RNA developed severe preeclampsia (PE). <b><i>Conclusion:</i></b> Among women diagnosed with COVID-19 during pregnancy, the presence of SARS-CoV-2 in the placenta was more frequent among women suffering from PE or gestational hypertension. Furthermore, the most severe cases of HDP were associated with high placental viral load, not necessarily associated with a positive nasopharyngeal RT-PCR at delivery. Our data suggest that SARS-CoV-2 infection during pregnancy could trigger gestational hypertensive disorders through persistent placental infection and resulting placental damage.

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