scholarly journals Identification of TB space-time clusters and hotspots in Ouest département, Haiti, 2011–2016

2021 ◽  
Vol 11 (2) ◽  
pp. 101-107
Author(s):  
A. M. Dismer ◽  
M. Charles ◽  
N. Dear ◽  
J. M. Louis-Jean ◽  
N. Barthelemy ◽  
...  

BACKGROUND: Haiti has the highest incidence rate of TB in the Western Hemisphere, with an estimated 170 cases per 100,000 in 2019. Since 2010, control efforts have focused on targeted case-finding activities in urban areas, implementation of rapid molecular diagnostics at high-volume TB centers, and improved reporting. TB analyses are rarely focused on lower geographic units; thus, the major goal was to determine if there were focal areas of TB transmission from 2011 to 2016 at operational geographic levels useful for the National TB Control Program (PNLT).METHODS: We created a geocoder to locate TB cases at the smallest geographic level. Kulldorff’s space-time permutation scan, Anselin Moran’s I, and Getis-Ord Gi* statistics were used to determine the spatial distribution and clusters of TB.RESULTS: With 91% of cases linked using the geocoder, TB clusters were identified each year. Getis-Ord Gi* analysis revealed 14 distinct spatial clusters of high incidences in the Port-au-Prince metropolitan area. One hundred retrospective space-time clusters were detected.CONCLUSION: Our study confirms the presence of TB hotspots in the Ouest département, with most clusters in the Port-au-Prince metropolitan area. Results will help the PNLT and its partners better design case-finding strategies for these areas.

Author(s):  
Kinley Wangdi ◽  
Kinley Penjor ◽  
Tobgyal ◽  
Saranath Lawpoolsri ◽  
Ric N. Price ◽  
...  

Malaria in Bhutan has fallen significantly over the last decade. As Bhutan attempts to eliminate malaria in 2022, this study aimed to characterize the space–time clustering of malaria from 2010 to 2019. Malaria data were obtained from the Bhutan Vector-Borne Disease Control Program data repository. Spatial and space–time cluster analyses of Plasmodium falciparum and Plasmodium vivax cases were conducted at the sub-district level from 2010 to 2019 using Kulldorff’s space–time scan statistic. A total of 768 confirmed malaria cases, including 454 (59%) P. vivax cases, were reported in Bhutan during the study period. Significant temporal clusters of cases caused by both species were identified between April and September. The most likely spatial clusters were detected in the central part of Bhutan throughout the study period. The most likely space–time cluster was in Sarpang District and neighboring districts between January 2010 to June 2012 for cases of infection with both species. The most likely cluster for P. falciparum infection had a radius of 50.4 km and included 26 sub-districts with a relative risk (RR) of 32.7. The most likely cluster for P. vivax infection had a radius of 33.6 km with 11 sub-districts and RR of 27.7. Three secondary space–time clusters were detected in other parts of Bhutan. Spatial and space–time cluster analysis identified high-risk areas and periods for both P. vivax and P. falciparum malaria. Both malaria types showed significant spatial and spatiotemporal variations. Operational research to understand the drivers of residual transmission in hotspot sub-districts will help to overcome the final challenges of malaria elimination in Bhutan.


Mediscope ◽  
2018 ◽  
Vol 5 (2) ◽  
pp. 12-15
Author(s):  
MS Mallick

The aim of this descriptive type of study on diagnosed tuberculosis (TB) cases was to evaluate the incidence of TB in Narail district to have a situational analysis with the achievement of National TB Control Program. Related data were collected from the Civil Surgeon Office, Narail district. The data of 3 upazilas- Narail Sadar, Kalia, and Lohagora were used. The study period was from January 1, 2016 to December 31, 2016. The overall TB case rate was 156.6 per 100000 population and separately 170.9 per 100000 population in Narail Sadar, 142.2 per 100000 population in Kalia and 156.6 per 100000 population in Lohagora. Of the cases, 56.4% were male and 43.6% female. Overall, 89.7% of the TB cases had pulmonary TB and 10.3% had extra-pulmonary TB. The population with higher age had higher proportion having TB. The highest number of patients were referred for diagnosis by sastha sebika (nurse) and non-government field staff. The TB incidence in Narail district was considered to be lower than the National situation. However, it seems that TB will remain as a continuous concern for many years in future for the country as well as Narail district. The activities of National TB Control Program of the Government of Bangladesh needs to be strengthened further to combat TB in BangladeshMediscope Vol. 5, No. 2: Jul 2018, Page 12-15


2019 ◽  
Vol 43 ◽  
pp. 1
Author(s):  
Cindy Córdoba ◽  
Lucy Luna ◽  
Diana M. Triana ◽  
Freddy Perez ◽  
Lucelly López

Objective.To determine factors associated with delays in pulmonary tuberculosis diagnosis and treatment initiation in the city of Cali, Colombia.Methods.This was a retrospective cohort study of cases of tuberculosis (TB) reported in the TB control program of Cali between January and December 2016. The information was collected from the databases of the TB control program, individual treatment cards, and clinical histories. The variables considered were sociodemographic factors, clinical factors, substance use, and performance of the health service.Results.A total of 623 cases were identified, of which 57.0% were male. The median age was 42 years (interquartile range (IQR): 27–60). The median time from onset of symptoms to TB diagnosis was 57 days (IQR: 21–117), and from onset of symptoms to TB treatment initiation was 72 days (IQR: 35–145). A factor associated with longer time from the onset of symptoms to TB treatment was being a previously treated TB patient (coefficient: 123.8 days, 95% confidence interval (CI): 48.3 to 199.3). In contrast, being incarcerated was a protective factor for earlier TB treatment initiation (coefficient: -57.3 days; 95% CI: -92.4 to -22.3).Conclusions.Our results provide important information concerning risk factors that are associated with delays in the diagnosis and treatment of tuberculosis, and that are subject to future interventions. Health insurance program managers must work together with health care providers on issues that include patient care, health promotion, and updating TB protocols and standards.


2021 ◽  
Vol 10 (1) ◽  
pp. 83
Author(s):  
Mawaddah Marahmah ◽  
Rapotan Hasibuan

TB cases in Southeast Asia contribute 40% of the world's TB cases and causes the highest mortality in Indonesia. Panyabungan Jae Health Center (PJHC) itself has the highest number of TB cases in Mandailing Natal Regency. This study, therefore, aimed to determine the implementation of the TB Control Program with the Directly Observed Treatment Shortcourse Strategy (DOTS) at PJHC.Qualitative methods with descriptive approach was used for this research. In-depth interviews was conducted with 5 informants in July 2020. The data were analyzed using data reduction, data presentation, and conclusion drawing.The research found that communication between the TB program officer and the DOTS strategy worked well in the PJHC as well as the disposition, resources and bureaucratic structures. Political commitment in the DOTS strategy with cross-sectoral cooperation has an important influence in the handling of TB cases,however village authorities have not played a role in efforts to reduce for number of TB cases. The patients had lack of understanding about TB and some localshad views TB as a disease caused by poison becomes an obstacle in treating patients. TB prevention with the DOTS strategy at the PJHC runs according to standard guidelines, and complemented by the Puskesmas innovation "Tor Tor Libas TB".The MNDHO officersare advised to collaborate with entire stakeholders in overcoming TB by strengthening education in the form of routine counseling to increase public knowledge about TB


Author(s):  
Khairunnisa B ◽  
Azizah Nasution

Objectives: to assess the pharmacists' perception about their roles in tuberculosis (TB) control program in Medan, Indonesia. Methods: A cross-sectional study was conducted to assess the pharmacists' perception about their roles in TB control program in Medan, Indonesia using a validated questionnaire. The pharmacists involved in this study (n=117) were asked to choose answering yes, no or do not know for their perception on their roles in TB control program. The collected data consisted of demographics (gender, age, place of practice, and working experience) and the pharmacists’ perception on their roles in TB control program were organized and analyzed by applying descriptive and Chi-square analyses using Statistical Package for the Social Sciences (SPSS, version 19, Chicago, IL, USA) (p value <0.05 was considered significant). Results: Mean age of the participants was 38.6 (standard deviation=11.7) years. Most of them (76.1%) were female. Distribution of the participants by place of practice:  pharmacy, 78.6%; hospital, 20.5%. Most of them (63.2%) have heard about directly observed treatment short-course (DOTS) program. More than 90% of them realized that they could play their roles as providers, managers of anti-TB drugs, drug informans, ensurers for adherence to the TB treatment, educators for patients and publics on TB and its treatment. Only 26.5% of them knew that they could also play their role as inventors of early suspected TB in the community.Conclusion: The study proved that the pharmacists’ roles could be utilized and enhanced to optimize TB control programs in Indonesia.Keywords: Pharmacists’ role, Tuberculosis, DOTS Program


Author(s):  
Sami Ullah ◽  
Hanita Daud ◽  
Sarat C. Dass ◽  
Hadi Fanaee-T ◽  
Husnul Kausarian ◽  
...  

The number of tuberculosis (TB) cases in Pakistan ranks fifth in the world. The National TB Control Program (NTP) has recently reported more than 462,920 TB patients in Khyber Pakhtunkhwa province, Pakistan from 2002 to 2017. This study aims to identify spatial and space-time clusters of TB cases in Khyber Pakhtunkhwa province Pakistan during 2015–2019 to design effective interventions. The spatial and space-time cluster analyses were conducted at the district-level based on the reported TB cases from January 2015 to April 2019 using space-time scan statistics (SaTScan). The most likely spatial and space-time clusters were detected in the northern rural part of the province. Additionally, two districts in the west were detected as the secondary space-time clusters. The most likely space-time cluster shows a tendency of spread toward the neighboring districts in the central part, and the most likely spatial cluster shows a tendency of spread toward the neighboring districts in the south. Most of the space-time clusters were detected at the start of the study period 2015–2016. The potential TB clusters in the remote rural part might be associated to the dry–cool climate and lack of access to the healthcare centers in the remote areas.


CHEST Journal ◽  
2012 ◽  
Vol 142 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Kimberlee S. Fong ◽  
J. Walton Tomford ◽  
Lucileia Teixeira ◽  
Thomas G. Fraser ◽  
David van Duin ◽  
...  

2021 ◽  
Vol 317 ◽  
pp. 04018
Author(s):  
Ro’isah ◽  
Anies ◽  
Mateus Sakundarno ◽  
Nur Jazuli

Indonesia Indonesia is in the third rank of countries with the highest tuberculosis (TB) globally, with TB case detection still below 70%. The strategy in the TB control program to increase TB case detection is community partnership through the TB community. However, the role of this community in detecting TB suspects has never been reported. This study aimed to determine the role of the TB community in detecting TB suspects in the Probolinggo Regency. This research is descriptive qualitative research. The population was all TB community members is 130 people. The sample was a purposive sampling method, consideration until it met the data saturation, namely 29 respondents. The data were collected employing interviewed sheets, then analyzed with thematic content. Data triangulation by Head of Infectious Diseases, the Probolinggo Regency Health and five people from each TB community at Puskesmas. From the interviews, it was found that 23 people (79%) could not invite TB suspects to undergo examination, and 25 people (86%) had conducted counselling but were still unable to explain and convince the community of the importance of medical examinations for TB suspects. It is necessary to increase the capacity of TB community members to improve their roles in detecting TB cases.


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