scholarly journals Amniotic fluid NF-kB concentration in pregnant women with a high risk of prenatal screening test results

2018 ◽  
Vol 89 (10) ◽  
pp. 577-580
Author(s):  
Haldun Arpacı ◽  
Omer Erkan Yapca
Keyword(s):  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Screening Test ◽  
Prenatal Screening ◽  
Test Results

scholarly journals The Presence of Mycotoxins in Human Amniotic Fluid

Toxins ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 409
Author(s):  
Karolina Gromadzka ◽  
Jakub Pankiewicz ◽  
Monika Beszterda ◽  
Magdalena Paczkowska ◽  
Beata Nowakowska ◽  
...  
Keyword(s):  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Prenatal Screening ◽  
Genetic Defects ◽  
Chromosomal Anomalies ◽  
Risk Characterization ◽  
Fusarium Mycotoxins ◽  
Human Amniotic Fluid ◽  
Toxic Metabolites

Mycotoxin exposure assessments through biomonitoring studies, based on the analysis of amniotic fluid, provides useful information about potential exposure of mothers and fetuses to ubiquitous toxic metabolites that are routinely found in food and the environment. In this study, amniotic fluid samples (n = 86) were collected via abdominal amniocentesis at 15–22 weeks of gestation from pregnant women with a high risk of chromosomal anomalies or genetic fetal defects detected during 1st trimester prenatal screening. These samples were analyzed for the presence of the most typical Aspergillus, Penicillium and Fusarium mycotoxins, with a focus on aflatoxins, ochratoxins and trichothecenes, using the LC-FLD/DAD method. The results showed that the toxin was present in over 75% of all the tested samples and in 73% of amniotic fluid samples from fetuses with genetic defects. The most frequently identified toxins were nivalenol (33.7%) ranging from <LOQ to 4037.6 ng/mL, and aflatoxins (31.4%), including aflatoxin G1, ranging from <LOQ to 0.4 ng/mL. Ochratoxin A and deoxynivalenol were identified in 26.7% and 27.9% of samples, respectively. Bearing in mind the above, the detection of mycotoxin levels in amniotic fluid is useful for the estimation of overall risk characterization with an attempt to link the occurrence of fetal abnormalities with exposure to mycotoxins in utero.

scholarly journals Efficiency of non-invasive prenatal screening in pregnant women at advanced maternal age

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui Zhu ◽  
Xiaoxiao Jin ◽  
Yuqing Xu ◽  
Weihua Zhang ◽  
Xiaodan Liu ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Predictive Value ◽  
Trisomy 21 ◽  
Maternal Age ◽  
Prenatal Screening ◽  
Advanced Maternal Age ◽  
Youden Index ◽  
Non Invasive ◽  
Sensitivity Specificity

Abstract Background Non-invasive prenatal screening (NIPS) is widely used as the alternative choice for pregnant women at high-risk of fetal aneuploidy. However, whether NIPS has a good detective efficiency for pregnant women at advanced maternal age (AMA) has not been fully studied especially in Chinese women. Methods Twenty-nine thousand three hundred forty-three pregnant women at AMA with singleton pregnancy who received NIPS and followed-up were recruited. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), receiver operating characteristic (ROC) curves and the Youden Index for detecting fetal chromosomal aneuploidies were analyzed. The relationship between maternal age and common fetal chromosomal aneuploidy was observed. Results The sensitivity, specificity, PPV, NPV of NIPS for detecting fetal trisomy 21 were 99.11, 99.96, 90.98, and 100%, respectively. These same parameters for detecting fetal trisomy 18 were 100, 99.94, 67.92, and 100%, respectively. Finally, these parameters for detecting trisomy 13 were 100, 99.96, 27.78, and 100%, respectively. The prevalence of fetal trisomy 21 increased exponentially with maternal age. The high-risk percentage incidence rate of fetal trisomy 21 was significantly higher in the pregnant women at 37 years old or above than that in pregnant women at 35 to 37 years old. (Youden index = 37). Conclusion It is indicated that NIPS is an effective prenatal screening method for pregnant women at AMA.

Amniotic fluid composition in pregnant women at high risk of preterm birth

2020 ◽  
Vol 8_2020 ◽  
pp. 82-87
Author(s):  
Khodzhaeva Z.S. Khodzhaeva ◽  
Gorina K.A. Gorina ◽  
Muminova K.T. Muminova ◽  
Ivanets T.Yu. Ivanets ◽  
Kessler Yu.V. Kessler ◽  
...  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Fluid Composition

Copper and Zinc in the Amniotic Fluid and Serum from High-Risk Pregnant Women

1979 ◽  
Vol 161 (3) ◽  
pp. 382-385 ◽  
Author(s):  
T. R. Shearer ◽  
E. W. Lis ◽  
K. S. Johnson ◽  
J. R. Johnson ◽  
G. H. Prescott
Keyword(s):  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Copper And Zinc

The Effect of Inhibin A on Prenatal Screening Results for Down Syndrome in the High Risk Czech Pregnant Women

2019 ◽  
Vol 65 (05/2019) ◽  
Author(s):  
Jaroslav Loucký ◽  
Silvie Bělášková ◽  
Richard Průša ◽  
Karel Kotaška
Keyword(s):  
Down Syndrome ◽  
High Risk ◽  
Pregnant Women ◽  
Prenatal Screening ◽  
Inhibin A

scholarly journals Screening of gestational diabetes mellitus using one-step versus two-step method: a comparative study

2020 ◽  
Vol 9 (8) ◽  
pp. 3372
Author(s):  
Deepti Khenwar ◽  
Juhi Agarwal ◽  
Sushruta Shriastava
Keyword(s):  
Diabetes Mellitus ◽  
High Risk ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Screening Test ◽  
Step Method ◽  
Group I ◽  
One Step ◽  
Group Ii

Background: Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable severity with onset or first recognition during the present pregnancy. It affects 7% of all pregnancies worldwide and in India it ranges from 6 to 9% in rural and 12 to 21% in urban area. The aim of this study was to compare the DIPSI criteria with the two-step method (Carpenter and Couston criteria.) and to study merits and demerits of one step and two step tests for GDM.Methods: A total 400 pregnant women of gestational age between 24-28 weeks attending antenatal clinic at this study tertiary care center were enrolled in this study. 200 pregnant women were enrolled in each of the study group (Group I OGTT and Group II DIPSI).Results: In Group I (OGTT) screening 47 (23.5%) were tested positive. In Group II cases, screening test results were found positive among 44 (22%). Out of 95 high-risk pregnant women 38 (40%) were positive for GDM by OGTT and 34 (35.78%) were positive by DIPSI. Out of 305 non high-risk pregnant women, 9 (2.95%) were positive for GDM by OGTT and 10 (3.27%) were positive by DIPSI.Conclusions: Present study concludes that DIPSI is the test which can predict GDM in population comparable to another test like OGTT. Also, India’s major population reside in rural areas, ANC are mostly conducted by ANM, therefore screening test should be easy to perform and interpret.

Association of abnormal fetal echocardiography with some obstetric records

2021 ◽  
Vol 29 (8) ◽  
pp. 448-452
Author(s):  
Mahin Najafian ◽  
Mojgan Barati ◽  
Sareh Aberumand ◽  
Nahal Nasehi ◽  
Abdolrahman Emami-moghaddam
Keyword(s):  
Down Syndrome ◽  
Retrospective Study ◽  
High Risk ◽  
Pregnant Women ◽  
Significant Relationship ◽  
Screening Test ◽  
Fetal Echocardiography ◽  
Aneuploidy Screening ◽  
Previous Child ◽  
History Of

Background To evaluate the history of some obstetrical records of pregnant women who were referred for fetal echocardiography for any reason. Methods This was a retrospective study on 1772 documents of referred pregnant women, which was conducted in Narges diagnostic clinic staff (Ahvaz city, Iran) from 2017-2020. In this study, all document data of pregnant women who referred for fetal echocardiography for any reason have been reviewed. Results Our study showed that there is a significant relationship between abnormal fetal echocardiography with history of miscarriage, stillbirth and a previous child with Down syndrome. Conclusion Although our study showed that abnormal fetal echocardiography was associated with stillbirth, miscarriage, and a history of having a previous child with Down syndrome, but many cases had abnormal echocardiography didn't have a history of having a previous child with CHD, increased NT and high-risk aneuploidy screening test.

Hearing Screening Test Results Of Newborns at High Risk for Developmentel Delay

2011 ◽  
Vol 1 (1) ◽  
pp. 1-6
Author(s):  
Erhan Ozbek ◽  
Fusun Atlihan ◽  
Ferah Genel ◽  
Sebnem Calkavur ◽  
Bilgin Bayar ◽  
...  
Keyword(s):  
High Risk ◽  
Screening Test ◽  
Hearing Screening ◽  
Test Results

scholarly journals Private Community Assistance in Antenatal Care at High Risk Pregnant Women in Public Health Center of Jelakombo Jombang

2020 ◽  
Vol 6 (1) ◽  
pp. 14-20
Author(s):  
Dewi Taurisiawati Rahayu ◽  
Askabulaikhah Askabulaikhah
Keyword(s):  
High Risk ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Health Center ◽  
Simple Random Sampling ◽  
Statistical Test ◽  
Test Results ◽  
Cross Sectional ◽  
Live Births ◽  
Independent Variable

  Maternal Mortality Rate (MMR) in 2012 was 359 per 100,000 live births. In 2015, based on 2015 SUPAS data, both MMR and IMR showed a decrease (MMR 305 / 100,000 KH; IMR 22.23 / 1000 KH). The purpose of this study was to determine the effect of the implementation of cadre assistance on antenatal care (ANC) visits of high-risk pregnant women in Jelakombo Jombang.This type of research is correlational with the Cross Sectional approach. Population 63 high risk pregnant women, sample 54 high risk pregnant women. The study was conducted from 03 to 17 July 2019. The independent variable was the implementation of cadre mentoring and the dependent variable was the ANC visit. The side technique used is simple random sampling. Data obtained from ANC questionnaire and MCH Book Checklist. Data analysis using the Mann Whitney test.The results of the implementation of cadre mentoring were quite good as many as 32 respondents (59.3%). ANC visits were mostly active in visiting ANC, namely 40 respondents (74.1%). Implementation of pregnant women by good cadres 32 respondents, most respondents 32 high risk mothers (93.8%) actively visited ANC. Statistical test results using the Mann-Whitney U test obtained r = 0,000 (r<0.05) so that Ho was rejected means that it was concluded there was a correlation between the Implementation of Cadre Assistance with ANC Visit of Risti Pregnant Women at Jelakombo Health Center in Jombang Regency.

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