Factors affecting D-dimer levels in patients with uncomplicated primary varicose veins

2021 ◽  
Vol 93 (5) ◽  
pp. 1-5
Author(s):  
Paweł Zawadzki ◽  
Anita Nowak ◽  
Lukasz Dzieciuchowicz
Keyword(s):  
Varicose Veins ◽  
Diagnostic Value ◽  
Descriptive Statistics ◽  
Bivariate Analysis ◽  
Spearman Correlation ◽  
Clinical Factors ◽  
Factors Affecting ◽  
Primary Varicose Veins ◽  
Overweight Subjects ◽  
D Dimer

Objectives The diagnosis of deep venous thrombosis (DVT) is hampered in patients with primary varicose veins due to similarity of symptoms of DVT and PVV and elevated levels of D-dimers. The purpose of this study was to analyze factors that influence the D-dimer concentration in patients with PVV in order to redefine its diagnostic value. Methods Forty- one patients with non-complicated PVV were enrolled in the study, in whom D-dimer level was determined by immunoturbidimetric assay. The influence of selected clinical factors on the concentration of D-dimers was determined with univariate and bivariate analysis. Besides descriptive statistics the D-dimers levels were compared to the age -adjusted cutoff values. Results The median concentration of D-dimer was 630.0 ng/ml (440.0-1140.0 ng/ml) and was above the age-adjusted level in 21 (52%) of patients. There was a positive correlation between the patient’s age and and D-dimer concentration (p = 0.035, Spearman correlation coefficient rs=0,33. The bivariate analysis showed a significant interaction between age and weight p=0,02. Conclusions In patients with PVV the diagnostic value of D-dimers is limited especially in older and overweight subjects.

Diagnostic Value of Plasma Thrombin-Antithrombin III Complex and D-Dimer Concentration in Patients with Varicose Veins for Exclusion of Deep-Vein Thrombosis

1998 ◽  
Vol 91 (2) ◽  
pp. 101-104 ◽  
Author(s):  
Tomio Kawasaki ◽  
Nobutoshi Shinoki ◽  
Shin-ichi Iwamoto ◽  
Hironobu Fujimura ◽  
Norihide Yoshikawa ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Antithrombin Iii ◽  
Varicose Veins ◽  
Diagnostic Value ◽  
Vein Thrombosis ◽  
Deep Vein ◽  
Thrombin Antithrombin Iii Complex ◽  
D Dimer

scholarly journals Oral Clinical Factors Affecting Self-Perception of Oral Health

2015 ◽  
Vol 62 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Dajana Nogo-Živanović ◽  
Ljiljana Kulić ◽  
Aleksandra Žuža ◽  
Brankica Davidović ◽  
Igor Radović
Keyword(s):  
Oral Health ◽  
Clinical Examination ◽  
Cost Effective ◽  
Bivariate Analysis ◽  
Clinical Factors ◽  
Self Perception ◽  
Missing Teeth ◽  
Self Assessment ◽  
Aged Patients ◽  
Factors Affecting

Abstract Introduction Self- assessment of oral health is simple, non-invasive and cost-effective method of collecting data that takes into account psychosocial aspects of oral health. The aim of this study was to investigate the effect of clinical factors on the self-perception of oral health in middle-aged patients in Republika Srpska (Bosnia and Herzegovina). Material and Methods The study included 126 subjects of both genders (34.1% male and 65.9% female) aged 24-54 years. Data were collected through questionnaires and clinical examination. Anonymous questionnaire contained questions related to socio-demographic characteristics of respondents. Clinical examination included teeth condition and the presence of prosthetic restorations. Self-perception of oral health was determined by one question. Results Bivariate analysis indicated significant effect of carious (p<0.001), missing (p<0.001) and filled teeth (p=0.022) but not the prosthetic status on self-perception of oral health. Correlation between the number of carious and missing teeth with self-perception of oral health was significant in regression analysis. Conclusion The number of carious and missing teeth had significant impact on self-assessment of oral health in studied population. Knowledge of effects of oral clinical variables on self-perception of oral health is very important to obtain clearer insight into the association between objectively and subjectively assessed oral health.

scholarly journals The factors affecting the illness perception in patients staying in a state hospital

2019 ◽  
pp. 1-17
Author(s):  
Nida Kiyici ◽  
Zeliha Koc ◽  
Zeynep Saglam ◽  
Sevil Masat
Keyword(s):  
Side Effects ◽  
State Hospital ◽  
Illness Perception ◽  
Descriptive Statistics ◽  
Spearman Correlation ◽  
Factors Affecting ◽  
Correlation Test ◽  
Illness Perception Questionnaire ◽  
Spearman Correlation Test ◽  
Questionnaire Form

This study was conducted as descriptive with an aim to determine the factors affecting the illness perception in patients. The study was conducted with the participation of 130 patients receiving treatment in a state hospital between March 25 and May 11, 2018. The data were collected using a questionnaire form consisting of 20 questions and the Illness Perception Questionnaire. Kruskal–Wallis test, Spearman Correlation test in addition to descriptive statistics were used for the evaluation of the data. The item that the patients received the highest score from the Illness Perception Questionnaire was ‘My treatment would be effective in healing my disease’ (3.83 ± 1.21) and the lowest score was from the item ‘Nothing can improve my condition’ (1.93 ± 1.12). It is recommended to organise training in order to strengthen the patients to deal with the side effects of their diseases. Keywords: Illness perception, behaviour, opinion.

Primary varicose veins

Phlebologie ◽  
2010 ◽  
Vol 39 (03) ◽  
pp. 133-137
Author(s):  
H. Partsch
Keyword(s):  
Varicose Veins ◽  
Compression Therapy ◽  
Daily Practice ◽  
Clinical Severity ◽  
Compression Stockings ◽  
Primary Varicose Veins ◽  
The Cost ◽  
Convincing Data ◽  
Long Term Studies

SummaryBackground: Compression stockings are widely used in patients with varicose veins. Methods: Based on published literature three main points are discussed: 1. the rationale of compression therapy in primary varicose veins, 2. the prescription of compression stockings in daily practice, 3. studies required in the future. Results: The main objective of prescribing compression stockings for patients with varicose veins is to improve subjective leg complaints and to prevent swelling after sitting and standing. No convincing data are available concerning prevention of progression or of complications. In daily practice varicose veins are the most common indication to prescribe compression stockings. The compliance depends on the severity of the disorder and is rather poor in less severe stages. Long-term studies are needed to proof the cost-effectiveness of compression stockings concerning subjective symptoms and objective signs of varicose veins adjusted to their clinical severity. Conclusion: Compression stockings in primary varicose veins are able to improve leg complaints and to prevent swelling.

D-Dimers, Thrombin Antithrombin III Complexes and Prothrombin Fragments 1 + 2: Diagnostic value in Clinically Suspected Deep Vein Thrombosis

1991 ◽  
Vol 65 (01) ◽  
pp. 028-032 ◽  
Author(s):  
B Boneu ◽  
G Bes ◽  
H Pelzer ◽  
P Sié ◽  
H Boccalon
Keyword(s):  
Deep Vein Thrombosis ◽  
Antithrombin Iii ◽  
High Sensitivity ◽  
Diagnostic Value ◽  
Predictive Values ◽  
Vein Thrombosis ◽  
High Negative Predictive Value ◽  
Deep Vein ◽  
D Dimer ◽  
Mercury Strain Gauge

SummaryThis study was performed to determine the accuracy of D-Dimer fibrin derivatives, thrombin-antithrombin III (TAT) complexes and prothrombin fragments 1 + 2 (F 1 + 2) determinations for the diagnosis of deep vein thrombosis (DVT). One hundred and sixteen consecutive patients referred to the angiology unit of our hospital for a clinically suspected DVT were investigated. They were submitted to mercury strain gauge plethysmography and to ultrasonic duplex scanning examination; in cases of inconclusive results or of proximal DVT (n = 35), an ascending phlebography was performed. After these investigations were completed, the diagnosis of DVT was confirmed in 34 and excluded in 82. One half of the patients were already under anticoagulant therapy at the time of investigation. The 3 biological markers were assayed using commercially available ELISA techniques and the D-Dimer was also assayed with a fast latex method. The normal distribution of these markers was established in 40 healthy blood donors. The most accurate assay for the diagnosis of DVT was the D-Dimer ELISA which had both a high sensitivity (94%) and a high negative predictive value (95%). The D-Dirner latex, TAT complexes and F 1 + 2 were far less sensitive and provided negative predictive values which ranged between 78 and 85%. In spite of positive and significant correlations between the levels of ihe 3 markers, their association did not improve their overall accuracy for detecting D\/L Therefore, with the exception of the D-Dimer ELISA, these markers were of little value for the diagnosis of DVT in this specific population.

scholarly journals The Assessment of Early Complications and Risk Factors Affecting Their Occurrence in Breast Reconstructive Procedures

2021 ◽  
Author(s):  
Justyna Jończyk ◽  
Jerzy Jankau
Keyword(s):  
Risk Factors ◽  
Postoperative Complications ◽  
Breast Reconstruction ◽  
Complication Rate ◽  
Clinical Factors ◽  
Early Complications ◽  
Reconstructive Procedures ◽  
Factors Affecting ◽  
Rehospitalization Rate ◽  
Early Postoperative Complications

AbstractThe presence of postoperative complications may have a significant impact on the outcome of the breast reconstruction. The aim of this study was to investigate early postoperative complications and the risk factors for their occurrence. A prospective analysis was carried out to evaluate surgical outcomes after breast reconstructive surgeries performed over a 2-year period. Procedures included expander/implant (TE/IMP), pedicle transverse rectus abdominis musculocutaneous (pTRAM), and latissimus dorsi (LD) techniques. All adverse events which occurred within 6 weeks of surgery were ranked according to severity based on the contracted Accordion grading system. Outcomes were assessed for their association with surgical, demographic, and clinical variables. Sixty-one consecutive breast reconstruction procedures were analyzed. The overall complication rate was 60.7% (n = 37), and 8 patients (13.1%) required reoperation. The lowest complication rate was observed in implant-based reconstructions (TE/IMP, 18.8%; pTRAM, 72.7%; LD, 78.3%; p = 0.008). Mild complications occurred significantly more often after LD reconstructions (LD, 60.9%; pTRAM, 22.7%; TE/IMP, 12.5%; p = 0.031), while severe complications were significantly more frequent after the pTRAM procedures (pTRAM, 27.3%; TE/IMP, 6.2%; LD, 8.7%; p = 0.047). Severe complications were associated with higher rehospitalization rate (p = 0.010) and longer hospital stay. Study revealed a significant impact of the operative method on the incidence and severity of early complications after breast reconstruction procedures with little effect from other demographic and clinical factors.

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