scholarly journals Hydroxyapatite-Based Coating on Biomedical Implant

Author(s):  
Wan Sharuzi Wan Harun ◽  
Rahil Izzati Mohd Asri ◽  
Abu Bakar Sulong ◽  
Saiful Anwar Che Ghani ◽  
Zakri Ghazalli
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Author(s):  
Torsten Lehmann ◽  
André van Schaik

The chapter Implantable hearing interfaces describes the fundamental operation of a commonly available biohybrid system, the cochlear implant, or bionic ear. This neuro-stimulating biomedical implant is very successful in restoring hearing function to people with profound hearing loss. The fundamental operation of the biological cochlea is described and parallels are drawn between key aspects of the biological system and the biohybrid implementation: dynamic range compression, translation of sound to neural activity, and tonotopic mapping. Critical considerations are discussed for simultaneously meeting biological, surgical, and engineering restrictions in successful biohybrid systems design. Finally, challenges in present and future cochlear implants are outlined and directions of current research given.



Author(s):  
Jon Andrade del Olmo ◽  
Leyre Pérez-Álvarez ◽  
Miguel Ángel Pacha-Olivenza ◽  
Leire Ruiz-Rubio ◽  
Oihane Gartziandia ◽  
...  


Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 748
Author(s):  
Katayoon Kalantari ◽  
Bahram Saleh ◽  
Thomas J. Webster

Metallic materials are widely used for fabricating medical implants due to their high specific strength, biocompatibility, good corrosion properties, and fatigue resistance. Recently, titanium (Ti) and its alloys, as well as stainless steel (SS), have attracted attention from researchers because of their biocompatibility properties within the human body; however, improvements in mechanical properties while keeping other beneficial properties unchanged are still required. Severe plastic deformation (SPD) is a unique process for fabricating an ultra-fine-grained (UFG) metal with micrometer- to nanometer-level grain structures. SPD methods can substantially refine grain size and represent a promising strategy for improving biological functionality and mechanical properties. This present review paper provides an overview of different SPD techniques developed to create nano-/ultra-fine-grain-structured Ti and stainless steel for improved biomedical implant applications. Furthermore, studies will be covered that have used SPD techniques to improve bone cell proliferation and function while decreasing bacterial colonization when cultured on such nano-grained metals (without resorting to antibiotic use).



2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ramesh K. Pokharel ◽  
Adel Barakat ◽  
Shimaa Alshhawy ◽  
Kuniaki Yoshitomi ◽  
Costas Sarris

AbstractConventional resonant inductive coupling wireless power transfer (WPT) systems encounter performance degradation while energizing biomedical implants. This degradation results from the dielectric and conductive characteristics of the tissue, which cause increased radiation and conduction losses, respectively. Moreover, the proximity of a resonator to the high permittivity tissue causes a change in its operating frequency if misalignment occurs. In this report, we propose a metamaterial inspired geometry with near-zero permeability property to overcome these mentioned problems. This metamaterial inspired geometry is stacked split ring resonator metamaterial fed by a driving inductive loop and acts as a WPT transmitter for an in-tissue implanted WPT receiver. The presented demonstrations have confirmed that the proposed metamaterial inspired WPT system outperforms the conventional one. Also, the resonance frequency of the proposed metamaterial inspired TX is negligibly affected by the tissue characteristics, which is of great interest from the design and operation prospects. Furthermore, the proposed WPT system can be used with more than twice the input power of the conventional one while complying with the safety regulations of electromagnetic waves exposure.



Author(s):  
Abdelali El Boutahiri ◽  
Mounir Ouremchi ◽  
Ahmed Rahali ◽  
Mustapha El Alaoui ◽  
Fouad Farah ◽  
...  

<p>In this work a 2 MHz on-off keying (OOK) transmitter/receiver for inductive power and data transmission for biomedical implant system is presented. Inductive link, driven by a Class E power amplifier (PA) is the most PA used to transfer data and power to the internal part of biomedical implant system. Proposed transmitter consists of a digital control oscillator (DCO) and a class E PA which uses OOK modulation to transfer both data and power to a biomedical implant. In proposing OOK transmitter when the transmitter sends binary value “0” the DCO and PA are turned off. With this architecture and 2 MHz carrier wave we have implemented a wireless data and power transfer link which can transmit data with data rate 1Mbps and bit error rate (BER) of 10-5. The efficiency of power transfer is 42% with a 12.7 uH transmitter coil and a 2.4 uH receiver coil and the power delivered to the load is about 104.7 mW. Proposed transmitter is designed for output power 4.1V. OOK receiver consists of an OOK demodulator, powered by rectified and regulated 5V p-p RF signal across the receiver coil. The supply voltage of proposed voltage regulator is 5 V with 9mV/V line regulation of. All circuits proposed in this paper were designed and simulated using Cadence in 0.18 um CMOS process.</p>



Crystals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 693 ◽  
Author(s):  
Myoungjae Lee ◽  
In-Su Kim ◽  
Young Hoon Moon ◽  
Hyun Sik Yoon ◽  
Chan Hee Park ◽  
...  

Metals for biomedical implant applications require a simultaneous achievement of high strength and low Young’s modulus from the viewpoints of mechanical properties. The American Society for Testing and Materials (ASTM) standards suggest two types of processing methods to confer such a mechanical performance to Ti-13Nb-13Zr alloy: solution treatment (ST) and capability aging (CA). This study elucidated the kinetics of CA process in Ti-13Nb-13Zr alloy. Microstructural evolution and mechanical change were investigated depending on the CA duration from 10 min to 6 h. The initial ST alloy possessed the full α′-martensitic structure, leading to a low strength, low Young’s modulus, and high ductility. Increasing CA duration increased mechanical strength and Young’s modulus in exchange for the reduction of ductility. Such a tendency is attributed to the decomposition of α′ martensite into (α+β) structure, particularly hard α precipitates. Mechanical compatibility (i.e., Young’s modulus compensated with a mechanical strength) of Ti-13Nb-13Zr alloy rarely increased by changing CA duration, suggestive of the intrinsic limit of static heat treatment.





2004 ◽  
Author(s):  
Robert N. Dean, Jr. ◽  
Jenny Weller ◽  
Michael Bozack ◽  
Brian Farrell ◽  
Linas Jauniskis ◽  
...  
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