scholarly journals Prevalence and Comorbidity of Anxiety and Depressive Disorders in Studies of PRIME-MD and PHQ (Patient Health Questionnaire) in Japan

2021 ◽  
Author(s):  
Kumiko Muramatsu ◽  
Hitoshi Miyaoka ◽  
Kunitoshi Kamijima ◽  
Yoshiyuki Muramatsu ◽  
Katsuya Fuse ◽  
...  

We examine two studies on the prevalence and comorbidity of anxiety and depressive disorders in Japanese patients in primary care settings. The PRIME-MD study (Primary Care Evaluation of Mental Disorders) in Japan was conducted in seven primary care sites. The sample group included 601 adult patients (249 males, 352 females, mean age = 58.9 years, SD = 16.5). Of the 12.5% of patients diagnosed with mood disorders, 5.0% (n = 29) were major depressive disorder, and 6.7% (n = 40) were minor depressive disorder. The odds ratio for co-occurrence of major depressive disorder with generalized anxiety disorders and major depressive disorder with anxiety disorders (NOS) was 11.5 (95% CI: 2.17–18.45) and 8.00 (95% CI: 3.19–20.07), respectively. The PHQ (Patient Health Questionnaire) study in Japan was conducted in eleven primary care sites. A total of 1409 adult patients (611 males, 797 females; mean age: 56.2 years, SD: ±20.4) completed the PHQ in full. The prevalence of diagnosis of any mood disorder or any anxiety disorder was 25.0%. Of the 15.8% of patients diagnosed with mood disorders, 5.3% were for major depression and 8.4% for other depressive disorders. The odds ratio for co-occurrence of major depressive disorder with other anxiety disorders was 30.4 (95% CI: 13.19–70.28).

2001 ◽  
Vol 89 (2) ◽  
pp. 274-278 ◽  
Author(s):  
Geetha Kumar ◽  
Anne H. Kim ◽  
David Krefetz ◽  
Robert A. Steer

The mood modules from the Primary Care Evaluation of Mental Disorders (PRIME-MD) and the Patient Health Questionnaire (PHQ) were administered to 17 (52%) female and 16 (48%) male adolescent (13–17 years old) psychiatric inpatients. The internal consistencies of both were good (KR-20 for PRIME-MD = .80, Cronbach coefficient α for Patient Health Questionnaire = .85). The correlation between the PRIME-MD and Patient Health Questionnaire total scores was .87 ( p < .001) and the point-biserial correlation of both questionnaires' total scores with being diagnosed with a Major Depressive Disorder was .54 ( p < .001). Both mood modules appeared to be equally effective in screening for a Major Depressive Disorder.


2015 ◽  
Vol 2 (1) ◽  
pp. e8 ◽  
Author(s):  
John Torous ◽  
Patrick Staples ◽  
Meghan Shanahan ◽  
Charlie Lin ◽  
Pamela Peck ◽  
...  

Background Accurate reporting of patient symptoms is critical for diagnosis and therapeutic monitoring in psychiatry. Smartphones offer an accessible, low-cost means to collect patient symptoms in real time and aid in care. Objective To investigate adherence among psychiatric outpatients diagnosed with major depressive disorder in utilizing their personal smartphones to run a custom app to monitor Patient Health Questionnaire-9 (PHQ-9) depression symptoms, as well as to examine the correlation of these scores to traditionally administered (paper-and-pencil) PHQ-9 scores. Methods A total of 13 patients with major depressive disorder, referred by their clinicians, received standard outpatient treatment and, in addition, utilized their personal smartphones to run the study app to monitor their symptoms. Subjects downloaded and used the Mindful Moods app on their personal smartphone to complete up to three survey sessions per day, during which a randomized subset of PHQ-9 symptoms of major depressive disorder were assessed on a Likert scale. The study lasted 29 or 30 days without additional follow-up. Outcome measures included adherence, measured by the percentage of completed survey sessions, and estimates of daily PHQ-9 scores collected from the smartphone app, as well as from the traditionally administered PHQ-9. Results Overall adherence was 77.78% (903/1161) and varied with time of day. PHQ-9 estimates collected from the app strongly correlated (r=.84) with traditionally administered PHQ-9 scores, but app-collected scores were 3.02 (SD 2.25) points higher on average. More subjects reported suicidal ideation using the app than they did on the traditionally administered PHQ-9. Conclusions Patients with major depressive disorder are able to utilize an app on their personal smartphones to self-assess their symptoms of major depressive disorder with high levels of adherence. These app-collected results correlate with the traditionally administered PHQ-9. Scores recorded from the app may potentially be more sensitive and better able to capture suicidality than the traditional PHQ-9.


2021 ◽  
Author(s):  
Patricia A Ganz ◽  
Julienne E Bower ◽  
Ann H Partridge ◽  
Antonio C Wolff ◽  
Elissa D Thorner ◽  
...  

Abstract Background Major cancer organizations recommend depression screening in patients and survivors. The Patient Health Questionnaire-9 (PHQ-9) is often suggested, with limited information about its use. Methods Enrollment data collected from younger breast cancer survivors participating in a behavioral intervention trial were used to examine the relationship between PHQ-9 scores (range = 0-27), patient characteristics and responses to standardized psychosocial assessment tools. Major depressive disorder criterion was met if responses to the first two PHQ-9 items (range = 0-6) were &gt;3. The sample was categorized by total PHQ-9 scores: &lt;5 (minimal depressive symptoms), 5-9 (mild to moderate depressive symptoms) and &gt;10 (moderate to severe depression). PHQ-9 category associations with medical, demographic, psychosocial and behavioral characteristics were examined using ANOVA for continuous variables and chi-square tests for categorical variables. Results 231 women met the study pre-screening eligibility criterion of mild depressive symptoms and enrolled in the study. On average, they were 45.2 years old and 2.6 years since diagnosis. At enrollment, 22.1% met the screening criterion for possible major depressive disorder; among those with PHQ-9 scores &gt;10, 58.3% met this criterion. Anxiety, fatigue, insomnia, and intrusive thoughts about cancer were frequent and were associated with depressive symptom severity (all Ps &lt;.001). In contrast, neither demographic nor cancer treatment characteristics were associated with depressive symptoms. Conclusions Depressive symptoms in this selected sample of younger breast cancer survivors were independent of demographic characteristics or cancer treatment history, suggesting that depression screening is necessary to detect uncontrolled depressive symptoms.


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