scholarly journals Effectiveness and Stability of Treatment with Orthodontics Clear Aligners: What Evidence?

2021 ◽  
Author(s):  
Soukaina Sahim ◽  
Farid El Quars
Keyword(s):  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Level Of Evidence ◽  
Vertical Movements ◽  
Fixed Appliance ◽  
Specific Protocol ◽  
The Stability ◽  
Almost All ◽  
Removable Appliance ◽  
Clear Aligner

Clear aligners, as a transparent and removable appliance, offer an alternative to conventional fixed appliance to patients with high demands for esthetics and comfort. Only a few investigations have focused on the efficacy of clear aligner therapy in controlling orthodontic tooth movement. Furthermore, the stability after treatment has not been thoroughly investigated. The purpose of this chapter was to update the knowledge of the available evidence about effectiveness and stability of clear aligners in non-growing subjects. Searches was made in different databases from January 2015 to January 2021. Relevant articles that met the inclusion criteria were selected. The level of evidence of the studies was moderate. The vertical movements of tooth were difficult to accomplish. Mesiodistal tipping showed the most predictability (82.5%) followed by vestibulolingual tipping. Molar distalization was also recorded as the highest accuracy. Derotation was difficult to accomplish with aligners especially of rounded teeth. The effectiveness of aligners in achieving the simulated transverse goals was 45%. The stability of clear aligner therapy was assessed by only two studies. Refinements are likely needed in almost all cases and to ensure treatment stability a retention period using a specific protocol is necessary.

scholarly journals Dynamics of Alloplastic Bone Grafts on an Early Stage of Corticotomy-Facilitated Orthodontic Tooth Movement in Beagle Dogs

2014 ◽  
Vol 2014 ◽  
pp. 1-13
Author(s):  
Hyung-Joo Choi ◽  
Dong-Yeol Lee ◽  
Tae-Woo Kim
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Early Stage ◽  
Orthodontic Tooth Movement ◽  
Bone Grafts ◽  
Periodontal Tissue ◽  
Histological Findings ◽  
Beagle Dogs ◽  
The Stability ◽  
Short Time

Alveolar augmented corticotomy is effective in accelerating orthodontic tooth movement, but the effect only lasts for a relatively short time. Therefore, the purpose of this study was to investigate the underlying biology of the immediate periodontal response to orthodontic tooth movement after a corticotomy with alloplastic bone grafts. The results demonstrated that measurable tooth movement began as early as 3 days after the intervention in beagle dogs. Based on the results and histological findings, augmented corticotomy-facilitated orthodontic tooth movement might enhance the condition of the periodontal tissue and the stability of the outcomes of orthodontic treatment.

scholarly journals Proteomic Analysis of Saliva Identifies Potential Biomarkers for Orthodontic Tooth Movement

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Mohd Faiz Ellias ◽  
Shahrul Hisham Zainal Ariffin ◽  
Saiful Anuar Karsani ◽  
Mariati Abdul Rahman ◽  
Shahidan Senafi ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Differentially Expressed ◽  
Salivary Proteins ◽  
Niti Wire ◽  
Two Dimensional Gel Electrophoresis ◽  
Fixed Appliance ◽  
Maldi Tof ◽  
Whole Saliva

Orthodontic treatment has been shown to induce inflammation, followed by bone remodelling in the periodontium. These processes trigger the secretion of various proteins and enzymes into the saliva. This study aims to identify salivary proteins that change in expression during orthodontic tooth movement. These differentially expressed proteins can potentially serve as protein biomarkers for the monitoring of orthodontic treatment and tooth movement. Whole saliva from three healthy female subjects were collected before force application using fixed appliance and at 14 days after 0.014′′ Niti wire was applied. Salivary proteins were resolved using two-dimensional gel electrophoresis (2DE) over a pH range of 3–10, and the resulting proteome profiles were compared. Differentially expressed protein spots were then identified by MALDI-TOF/TOF tandem mass spectrometry. Nine proteins were found to be differentially expressed; however, only eight were identified by MALDI-TOF/TOF. Four of these proteins—Protein S100-A9, immunoglobulin J chain, Ig alpha-1 chain C region, and CRISP-3—have known roles in inflammation and bone resorption.

scholarly journals Salivary leptin levels in normal weight and overweight individuals and their correlation with orthodontic tooth movement

2017 ◽  
Vol 87 (5) ◽  
pp. 739-744 ◽  
Author(s):  
Tamizhmani Jayachandran ◽  
Bhadrinath Srinivasan ◽  
Sridevi Padmanabhan
Keyword(s):  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Normal Weight ◽  
Time Intervals ◽  
Fixed Appliance ◽  
Premolar Extraction ◽  
Force Application ◽  
Overweight Group ◽  
Baseline Values ◽  
The Mean

ABSTRACT Objectives: To assess and compare the concentration of leptin in saliva between normal weight and overweight individuals and to evaluate the rate of orthodontic tooth movement. Materials and Methods: Thirty female subjects were divided into two groups: I (normal weight) and II (overweight group) based on their body mass index. All subjects underwent fixed appliance therapy requiring upper first premolar extraction and distal movement of the canine. Distal force was applied to the maxillary right canine using active lacebacks. Salivary samples were collected just before force application (T0), 1 hour (T1), and 1 month (T2) after force application. The rate of tooth movement was evaluated over 3 months and was measured on study models. Results: At all three time intervals, mean leptin concentration was greater in overweight individuals than normal weight individuals. In both groups at T1, the mean leptin concentration was found to increase significantly compared with the baseline value (T0), but at T2, the leptin concentration declined to values lesser than the baseline values (T0). Conclusions: Overweight individuals had greater salivary leptin concentration. There was a positive correlation between salivary leptin concentration and rate of tooth movement in both normal and overweight individuals. The rate of tooth movement is decreased in overweight individuals as compared with normal weight individuals.

scholarly journals Effects of Different Parameters of Diode Laser on Acceleration of Orthodontic Tooth Movement and Its Effect on Relapse: An Experimental Animal Study

2019 ◽  
Vol 7 (3) ◽  
pp. 412-420 ◽  
Author(s):  
Aya Ehab Elkattan ◽  
Mostafa Gheith ◽  
Mona Salah Fayed ◽  
M. Abo El Yazeed ◽  
Abdel-Razik H. Farrag ◽  
...  
Keyword(s):  
Diode Laser ◽  
Low Dose ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Low Level Laser Therapy ◽  
Control Group ◽  
High Dose ◽  
Orthodontic Appliance ◽  
Dose Irradiation ◽  
Specific Protocol

AIM: Recent studies have demonstrated that low-level laser therapy (LLLT) can accelerate orthodontic tooth movement. However, there is still controversy about the optimum parameters that can cause acceleration. The present study was designed to examine two different doses of LLLT in the acceleration of orthodontic tooth movement and their effect on relapse. METHODS: An orthodontic appliance was designed to induce tooth movement on lower incisors of rabbits. The in-al-as diode laser was used to radiate different groups of rabbits according to a specific protocol. The amount of tooth movement was measured for 21 days, and then the orthodontic appliance was removed, and the relapse was measured till day 28. RESULTS: The amount of tooth movement was significantly greater in the group with irradiation of low dose in comparison with the high dose group and the control group. The relapse was greatest in the group of low dose irradiation and least in the control group. CONCLUSION: The findings suggest that LLLT with a low dose accelerate the orthodontic tooth movement while LLLT with a high dose was not able to have the same effect. LLLT had a reverse effect on relapse tendency; an increase in the relapse tendency was seen with low dose irradiation.

Inferior alveolar nerve anaesthesia: A rare complication of orthodontic tooth movement

2019 ◽  
Vol 46 (4) ◽  
pp. 374-377 ◽  
Author(s):  
Hanya Mahmood ◽  
Melanie Stern ◽  
Simon Atkins
Keyword(s):  
High Risk ◽  
Tooth Movement ◽  
Rare Complication ◽  
Inferior Alveolar Nerve ◽  
Third Molar ◽  
Orthodontic Tooth Movement ◽  
High Strength ◽  
Third Molar Surgery ◽  
Fixed Appliance ◽  
Dental Procedures

Inferior alveolar nerve (IAN) damage is a rare but recognised complication of dental procedures including third molar surgery, implant surgery, endodontic treatment and local anaesthetic injections. However, it is rarely caused by orthodontic tooth movement. This report highlights a case of temporary IAN anaesthesia to the right mental region, which was likely to have occurred secondary to the orthodontic uprighting of a lingually tilted molar using a high strength arch wire. Immediate deactivation of the appliance and an acute reducing dose of systemic steroids resulted in complete resolution of symptoms. To the best of the author’s knowledge, there have been seven previously described cases of IAN paraesthesia but no cases reporting IAN anaesthesia secondary to orthodontic fixed-appliance treatment. This case highlights the importance of dentists practising orthodontics to have an awareness of the clinical and radiographic signs that may indicate a high-risk case requiring appropriate referral for cone beam imaging and careful orthodontic planning. Furthermore, this case emphasises the need to warn high-risk patients of the symptoms of this rare complication and how it may be managed. This will ultimately help to minimise the risk of litigation and optimise patient experience and care.

Biomarkers of orthodontic tooth movement with fixed appliances and vibration appliance therapy: a pilot study

2020 ◽  
Vol 42 (4) ◽  
pp. 378-386 ◽  
Author(s):  
Stacey Reiss ◽  
Marie Claude Chouinard ◽  
Dasha Frias Landa ◽  
Ravindra Nanda ◽  
Taranpreet Chandhoke ◽  
...  
Keyword(s):  
Tooth Movement ◽  
Bone Remodelling ◽  
Orthodontic Tooth Movement ◽  
Small Sample ◽  
Fixed Appliance ◽  
Time Points ◽  
Salivary Biomarkers ◽  
Anterior Teeth ◽  
Fixed Appliances ◽  
Time Point

Summary Introduction The aim of this study was to investigate the effect of supplemental vibratory force on biomarkers of bone remodelling during orthodontic tooth movement, the rate of mandibular anterior alignment (RMAA), and compliance with a vibration device. Design, settings, and participants Forty patients between the ages 15–35 undergoing fixed appliance treatment that presented to a university orthodontic clinic were randomly allocated to supplemental use of an intraoral vibrational device (n = 20, AcceleDent®) or fixed appliance only (n = 20). Salivary multiplex assay was completed to analyse the concentration of selected biomarkers of bone remodelling before treatment (T0) and at three following time points (T1, T2, T3), 4–6 weeks apart. Irregularity of the mandibular anterior teeth and compliance was assessed at the same trial time points. Data were analysed blindly on an intention-to-treat basis with descriptive statistics, Mann–Whitney U-test, Wilcoxon signed-rank test, and linear mixed effects regression modelling. Results No difference in the changes in salivary biomarkers of bone remodelling and RMAA between groups at any time point over the trial duration was observed. No correlation was found between changes in irregularity and biomarker level from baseline to another time point. Lastly, there was no association between RMAA and compliance with the AcceleDent® device. Conclusions Supplemental vibratory force during orthodontic treatment with fixed appliances does not affect biomarkers of bone remodelling or the RMAA. Limitations The main limitation of the study was the small sample size and the large variability in the salivary biomarkers. Harms No harms were observed during the duration of the trial. Protocol The protocol was not published prior to trial commencement. Registration The study was registered in Clinical Trials.gov (NCT02119455) first posted on April 2014.

scholarly journals CLINICAL SIGNIFICANCE OF THE LEVELS OF THE GINGIVAL CREVICULAR FLUID VOLUME AND LEPTIN DURING ORTHODONTIC TOOTH MOVEMENT

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Kumari Upasana ◽  
Dr. Shivendra Choudhary
Keyword(s):  
Immune System ◽  
Periodontal Disease ◽  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Orthodontic Tooth Movement ◽  
Keywords Leptin ◽  
Niti Wire ◽  
Fixed Appliance ◽  
Periodontal Tissues

It is assumed that leptin has a role in protecting gingival tissues, leptin stimulates the immune system and enhances bone formation by acting directly on osteoblasts. As periodontal disease progresses, the protective role of leptin on the gingiva is lost owing to a decrease in the leptin level. During orthodontic tooth movement, the early response of periodontal tissues to mechanical stress is an acute infammatory reaction. Study of leptin therefore is a useful guide to determine its relationship with tooth movement in both tension and pressure sites and the role of this cytokine in controlling the local infammation around the tooth. Detection of the leptin level in GCF at sites under orthodontic movement had been tested and it was found that the concentration of leptin in GCF is decreased by orthodontic tooth movement. The present study was planned in Department of Periodontology, Manipal College of Dental Sciences Manipal. Total 20 cases were evaluated in the present study. The 10 cases were enrolled in Group A as study cases and 10 cases were enrolled in control cases. The selected 10 patients were bonded with fixed appliance 0.022" PEA bracket slot, MBT prescription. The maxillary right canines (control tooth, CT) were not bonded with the bracket. The initial wire will be 0.016" NiTi wire. The distalisation force were applied on the left canine (test tooth, TT) using 0.010 SS lace backs. Significantly decreased levels of leptin concentration might result from the presence of inflammation adjacent to the teeth undergoing movement. It has been shown previously that orthodontic tooth movement may therefore show local traits of a damage/ repair process with inflammation-like reactions: high vascular activity, many leukocytes and macrophages, and involvement of the immune system. Keywords: Leptin levels, periodontal disease activity, orthodontic tooth movement, ininflammatory  markers

scholarly journals Effect of Drugs on Orthodontic Tooth Movement in Human Beings: A Systematic Review of Randomized Clinical Trials

2019 ◽  
Vol 13 (1) ◽  
pp. 22-32
Author(s):  
Khaled Khalaf ◽  
Mahmoud Mando
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Tooth Movement ◽  
Treatment Time ◽  
Orthodontic Tooth Movement ◽  
Final Analysis ◽  
Human Beings ◽  
Level Of Evidence ◽  
Hand Search ◽  
The Impact

Background:Orthodontic tooth movement represents a series of events at both cellular and molecular levels which in turn stimulates inflammatory pathway to induce tooth movement. Some drugs taken by patients have a negative effect which can block this pathway, on the other hand, others may influence these events and reduce treatment time.Search Methods:A search strategy was implemented using both manual hand search and electronic databases, including Cochrane database of clinical trials, PubMed, ScienceDirect and Scopus. The risk of biased eligible studies to be included in the final analysis was assessed independently by two authors using Cochrane risk of bias tool.Results:A total of 491 articles were identified in both manual and electronic searches as well as by checking the reference lists of articles to be included in the study. After reviewing the titles, abstracts and full-text articles, only 8 RCTs met the inclusion criteria, and thus, were included in the final analysis. Six out of the 8 RCTs were assessed as of low quality. No statistical methods were employed to combine the studies due to the heterogeneities of the studies and the low level of evidence.Conclusion:Acetylsalicylic acid and ibuprofen reduced orthodontic tooth movement whereas paracetamol, Rofecoxib and tenoxicam had no impact on orthodontic tooth movement. Due to the low quality of the studies included, therefore to base our practice on scientific evidence, better-controlled RCTs are needed to investigate the impact of common medications on orthodontic tooth movement.

Sign in / Sign up

Export Citation Format

Share Document