scholarly journals Investigation of SARS-CoV-2 Ability to Pass Through the Placenta

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Fahimeh Ghotbizadeh ◽  
Farzaneh Nazari ◽  
Sedigheh Hantoushzadeh ◽  
Zahra Panahi ◽  
Zahra Naeiji
Keyword(s):  
Life Cycle ◽  
High Risk ◽  
Global Health ◽  
Web Of Science ◽  
Virus Entry ◽  
Risk Groups ◽  
Health Crisis ◽  
Pass Through ◽  
Immune Barriers ◽  
Maternal Fetal Interface

Context: Recently, a new coronavirus (SARS-CoV-2) as the cause of COVID-19 has made a global health crisis and a great challenge. Pregnant women and fetuses are among the high-risk groups for COVID-19. In this review, we summarize studies regarding SARS-CoV-2 virus-placenta interactions at the maternal-fetal interface by demonstrating the pathogenicity of the virus and defense methods of the placenta. Evidence Acquisition: In the present study, a search was done in domestic and international databases including Google Scholar, Web of Science, PubMed, and Scopus using specific keywords (“Coronavirus” OR “COVID-19” OR “SARS-CoV-2”) AND (“Fetus” OR “Placenta”) AND (“Pregnancy”), limited until August 2020. Finally, we reviewed 250 articles. Results: Generally, the pathogenicity and the life cycle of SARS-CoV-2 and virus entry and replication methods allow the virus to pass through the placenta, although there are hormonal and immune barriers in the placenta against SARS-CoV-2, such as placental type interferons. Conclusions: The SARS-CoV-2 can pass through the placenta, but there are defense methods against it.

scholarly journals Oesophageal tuberculosis with concomitant candidiasis: a rare cause of dysphagia

2019 ◽  
Vol 12 (11) ◽  
pp. e231435
Author(s):  
Nolitha Makapi Tisetso Morare ◽  
David Morris Rose ◽  
Olivia Appels
Keyword(s):  
Developing Countries ◽  
High Risk ◽  
Global Health ◽  
Antiretroviral Treatment ◽  
Systemic Infection ◽  
Risk Groups ◽  
Newly Diagnosed ◽  
Health Crisis ◽  
The World ◽  
High Index Of Suspicion

We present a case of a 23-year-old woman with dysphagia. She was reportedly newly diagnosed with HIV and had been initiated on antiretroviral treatment and tuberculosis (TB) prophylaxis. Oesophagogastroduodenoscopy revealed an irregular, ulcerative oesophageal lesion. Subsequent histopathology revealed Mycobacterium tuberculosis as well as Candida albicans. A CT scan demonstrated widespread disease with miliary TB. She was subsequently initiated on antituberculous and antifungal medications. TB is one of the most common and deadly infectious diseases in the world, with the highest rates seen in the developing countries. It commonly occurs as an opportunistic infection of HIV. Despite its potential for systemic infection, infection of the oesophagus is incredibly rare, more so as a co-infection with candida. This case highlights the need to have a high index of suspicion in high risk groups, as early treatment is crucial in addressing this global health crisis.

scholarly journals A Global Perspective on Psychologists' and Their Organizations' Response to a World Crisis

2021 ◽  
Vol 55 (2) ◽  
pp. e1713
Author(s):  
Germán Gutiérrez ◽  
Oscar Barbarin ◽  
Martina Klicperová-Baker ◽  
Prakash Padakannaya ◽  
Ava Thompson ◽  
...  
Keyword(s):  
Public Health ◽  
High Risk ◽  
Health Care Providers ◽  
General Public ◽  
Risk Groups ◽  
Global Perspective ◽  
Care Providers ◽  
Health Crisis ◽  
Social And Emotional ◽  
World Crisis

Around the world, individual psychologists have stepped up to deliver essential services to address the social and emotional sequelae of the COVID-19 pandemic. Many psychological organizations have also responded to this public health crisis, though their efforts may be less widely recognized. Psychological organizations engaged in preventive and mitigation efforts targeted, among others, the general public, local communities, and high-risk groups such as health care providers. They disseminated mental health information to the general public, trained laypersons to provide psychological first aid, and used research to design and evaluate public health responses to the pandemic. In some countries, psychological organizations contributed to the design and implementation of public health policies and practices. The nature of these involvements changed throughout the pandemic and evolved from reactive to proactive, from local to international. Several qualities appear key to the value, impact, and success of these efforts. These include organizational agility and adaptability, the ability to overcome their political inertia and manage conflict, recognizing the need to address cultural differences, and allocating limited resources to high-risk and resource-depleted constituencies where it was needed most.

Suicide in Nógrád County, Hungary, 1970-1994

Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 64-70 ◽  
Author(s):  
Tamás Zonda
Keyword(s):  
High Risk ◽  
Psychiatric Disorders ◽  
Suicide Rate ◽  
Risk Groups ◽  
The Elderly ◽  
Female Ratio ◽  
Suicide Notes ◽  
Suicidal Intention ◽  
Male Female Ratio

The author examined completed suicides occurring over a period of 25 years in a county of Hungary with a traditionally low (relatively speaking) suicide rate of 25.8. The rates are clearly higher in villages than in the towns. The male/female ratio was close to 4:1, among elderly though only 1.5:1. The high risk groups are the elderly, divorced, and widowed. Violent methods are chosen in 66.4% of the cases. The rates are particularly high in the period April-July. Prior communication of suicidal intention was revealed in 16.3% of all cases. Previous attempts had been undertaken by 17%, which in turn means that 83% of suicides were first attempts. In our material 10% the victims left suicide notes. Psychiatric disorders were present in 60.1% of the cases, and severe, multiple somatic illnesses (including malignomas) were present in 8.8%. The majority of the data resemble those found in the literature.

A(H1N1)v cases of the 2009/2010 and 2010/2011 influenza seasons in the Medical and Health Sciences Centre of Debrecen University

2012 ◽  
Vol 153 (17) ◽  
pp. 649-654
Author(s):  
Piroska Orosi ◽  
Judit Szidor ◽  
Tünde Tóthné Tóth ◽  
József Kónya
Keyword(s):  
High Risk ◽  
Influenza Season ◽  
National Level ◽  
Organ Transplant ◽  
High Risk Patient ◽  
Risk Groups ◽  
Health Sciences ◽  
World Health ◽  
Transplant Patients ◽  
Health Organization

The swine-origin new influenza variant A(H1N1) emerged in 2009 and changed the epidemiology of the 2009/2010 influenza season globally and at national level. Aims: The aim of the authors was to analyse the cases of two influenza seasons. Methods: The Medical and Health Sciences Centre of Debrecen University has 1690 beds with 85 000 patients admitted per year. The diagnosis of influenza was conducted using real-time polymerase chain reaction in the microbiological laboratories of the University and the National Epidemiological Centre, according to the recommendation of the World Health Organization. Results: The incidence of influenza was not higher than that observed in the previous season, but two high-risk patient groups were identified: pregnant women and patients with immunodeficiency (oncohematological and organ transplant patients). The influenza vaccine, which is free for high-risk groups and health care workers in Hungary, appeared to be effective for prevention, because in the 2010/2011 influenza season none of the 58 patients who were administered the vaccination developed influenza. Conclusion: It is an important task to protect oncohematological and organ transplant patients. Orv. Hetil., 2012, 153, 649–654.

Obesity – a global health crisis

2014 ◽  
pp. 9-10
Author(s):  
Hannah Brinsden
Keyword(s):  
Global Health ◽  
Health Crisis

ON THE ROLE OF BIOMONITORING IN THE ASSESSMENT OF THE HEALTH OF THE POPULATION EXPOSED TO MERCURY

2017 ◽  
pp. 2-7
Author(s):  
L. V. Lukovnikova ◽  
G. I. Sidorin ◽  
L. A. Alikbaeva ◽  
A. V. Galochina
Keyword(s):  
High Risk ◽  
Biological Monitoring ◽  
Clinical Examination ◽  
Inorganic Compounds ◽  
Risk Groups ◽  
Comprehensive Approach ◽  
Chemical Monitoring ◽  
Environmental Objects

When examining the population exposed to organic and inorganic compounds of mercury, a comprehensive approach is proposed, including chemical monitoring of environmental objects, biological monitoring, clinical examination of persons exposed to mercury, identification of high-risk groups.

scholarly journals A Peri-Implant Disease Risk Score for Patients with Dental Implants: Validation and the Influence of the Interval between Maintenance Appointments

2019 ◽  
Vol 8 (2) ◽  
pp. 252 ◽  
Author(s):  
Miguel de Araújo Nobre ◽  
Francisco Salvado ◽  
Paulo Nogueira ◽  
Evangelista Rocha ◽  
Peter Ilg ◽  
...  
Keyword(s):  
High Risk ◽  
Risk Score ◽  
Disease Risk ◽  
Disease Incidence ◽  
Risk Groups ◽  
Risk Profile ◽  
Moderate Risk ◽  
C Statistic ◽  
Disease Risk Score ◽  
Very High

Background: There is a need for tools that provide prediction of peri-implant disease. The purpose of this study was to validate a risk score for peri-implant disease and to assess the influence of the recall regimen in disease incidence based on a five-year retrospective cohort. Methods: Three hundred and fifty-three patients with 1238 implants were observed. A risk score was calculated from eight predictors and risk groups were established. Relative risk (RR) was estimated using logistic regression, and the c-statistic was calculated. The effect/impact of the recall regimen (≤ six months; > six months) on the incidence of peri-implant disease was evaluated for a subset of cases and matched controls. The RR and the proportional attributable risk (PAR) were estimated. Results: At baseline, patients fell into the following risk profiles: low-risk (n = 102, 28.9%), moderate-risk (n = 68, 19.3%), high-risk (n = 77, 21.8%), and very high-risk (n = 106, 30%). The incidence of peri-implant disease over five years was 24.1% (n = 85 patients). The RR for the risk groups was 5.52 (c-statistic = 0.858). The RR for a longer recall regimen was 1.06, corresponding to a PAR of 5.87%. Conclusions: The risk score for estimating peri-implant disease was validated and showed very good performance. Maintenance appointments of < six months or > six months did not influence the incidence of peri-implant disease when considering the matching of cases and controls by risk profile.

scholarly journals SEROPREVALENCE OF LEPTOSPIROSIS IN HIGH RISK GROUPS IN CALICUT, NORTH KERALA, INDIA

2006 ◽  
Vol 24 (4) ◽  
pp. 349-352
Author(s):  
RN Swapna ◽  
U Tuteja ◽  
L Nair ◽  
J Sudarsana
Keyword(s):  
High Risk ◽  
Risk Groups
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